MidgeBase gene description page [Pn.16857]
Outline
| Gene ID | Pn.16857 |
| Type | Protein coding gene |
| Scaffold | PnScaf44635 |
| Start | 3222 |
| End | 7293 |
| Direction | + |
Sequence
Transcript: 3024 (bp)
ATGAAGGTCAATCATTCTTCGCTAGCCTGCAATTTGAATACAAATGTTATTCCTGAACCCGACATTCAAATGCTGAAAACTTTAAATAAACTCTCTTTCAGTAATACCGATGGAGGAGTTTGGAAACAAGGTTTCAACATAACTTATGATTCAAATTTATGGAATTCATCACGAAAATTAAAAGTGTTTATTGTTCTTCATAGTCATAATGATCCAGGATGGATTTACACTTTCGATGAATACTACAGACAGCAAACGATAAACATTTTTAAAAATATGCTCAAATATTTGAGTAAGAATTCAAAATTAAAGTTCATATGGGCTGAAATTGTATATTTCTCAAAATGGTATGAAGGCCTACCAGAAAGTGTAAGACAAGAAGTTCAGAAGATTGTAAGCAATGGACAACTTGAGTTTGTGACTGGTGGCTGGGTAATGCCTGACGAGGCAGCTTCGCACTGGTACTCAGTACTTCTTTCACTAACCGAAGGGCAGACCTGGTTAAAAGAAAATCTTAACGTTACAAACATTAAATCGTCGTGGGCTATTGATCCCTTTGGACATTCATCCTCGTTTCCTTTCATTCTAAAGCAAGCTGGCTTTGAAAACCTGCTCATCCAAAGAACCCACTATTCTATTAAAAAGTATCTTGCCAAGCGTAAACAGTTAGAGTTCAGGTGGCAGCAACTTTGGGATTTTAAAGGAAATAGCGAAATATTTACTCACATGATGCCATTTTATAGCTACGATATTCCACACACATGTGGTCCAGATCCAAAAGTTTGCTGCCAATTCGACTTTAGACGTTCGTTTTGTCCCTGGAACGTGAATCCTGTAGAAATCGATGATACAAATATACTTCAAAAAAGTAAGCTGTTGGTTGATCAGTGGAAGAAAAAGTCACAGCTTTTCAGAAGCAAATCACTGTTAACTCCTGTCGGTGACGATTTTACTTATCAATCCGATTGGGAATGGAAGGTTCAAACAACAAACTTTGAAAAACTCATCAATTTTATAAACAAAAATGTAGAATTTAATGTTGAAGTGAAGTTTGCAACACTTCAGGAATATTTTGATTCAGTAAAGAATGAAACAATTGATTTTCCGTCTTTGAGCGGTGACTTTTTCACATATGCTGATAGAGATAGTCATTATTGGTCTGGTTATTTTACATCTCGCCCTTTCTACAAACAAACCGATCGCATTCTTCTCAACTACCTTAGAACAGCGGAAATTTTTAGCACACTTGCAAATTTTAGAAGCATTCAAACATTGAATTCCTATCTTAAATATGCACGAAGAGCTCTTTCAATTTTTCAACATCATGATGGGGTATCCGGAACGGCAAGAGACAATGTTATGCAAGACTATAATAATATGATGATACAGGGCATCGAAAAGAGCAAGTTTGTTATACAACAAGCGGTTTATAAACTGATGACCGATGCATTCAATTATATACCCGACCATACAATCAAATACTTTGACTTTGATGATACACATAGTGCTGGTGATAATAACATAGAAGAGCGCAGAACAATTATTATCGATACTCTCGAAAAGTTCATCATTATTCAGAACTCGCAAGCATACGACCGGGAGGAGATTGTCGAATTTATTATTGATAGCCAGCATGCGTGCATTACGGATGTAAAGGGAAAATCAGTCGATGCACAAATCAGTCCGATGTGGAATTTTATCGGCAATAATTCATTTATTGAGTTTGAAAATCGTAAGTTTAGACTGATTTTTAAAGCAAAAGTTTCAGCGTTTGGCATAACCGTATATAAAGTATACAAATGCAAAGACTGTGGGTCAGTAAAGTACGCCCAAGTAAAAATTTATTCAAATTCTAACTACGAAATTTCATTTGACTATGCGGGCCGCATCCAGGTCTTGAAGCCTACACAATTTAGTCTGAAAGTAGCCGACAGCTCCTTGAATTTTCAAGGAAATGGGCTTATGCAATCAGCATTGATTAGCGGTGTATTTACATCACTTAACATTGAATTTATGACTTACGGCACCAATTATACAAAAGACCAATGGAGTGGCGCTTATATATTCCTGCCAGATGGACCAGCCAAAGCTATTAATGTTTCTTCAATAACAAGTCCTGTCGTTGTGATTGAAGGGCCGTTGGAGTCGTCAATGACAACTAACCTGACGTTTATTAATCACACAATAATACTGAGGAGCCATAGCAAGGCTATTGAAATTCGAAATATTGTTGATATTCGTAACATGAACAACACTGAAATAATTATGCGAGTAAATACGATGAAAATAAAGAACTACAATGTTTTTTATACTGATCTTAATGGCCTACAATATGTAAAGAGAAAGATACTTGGACTTGTGCCATTACAAGGTAATTATTATCCGGTGAATTCAGGCATCTTCATTGAGGACAAAAAATTTCGTTTATCATTATTTACGGCTACACCACTTGGCGGTTCTTCACTGGATTCTGGACAAATTGAAGTTATGCAAGACAGGCGACATAGTCACGACGATAACAGAGGTCTTGGTCAAGGTGTTCTTGATAATCGTCCAGTACTCAACATCTTTAAATTACTGATTGAGAACCGGTCAGAGTGCAAACAATTGGATGAAAAGTATCAAATGGCTTTTCTTTCGAGGGAAGCATATCGAGAACAGAAAGGGCTTCTTCATCCGCTTCATAAATTGATTTTTACACGTGGAGAAAATTGGAACGGAGTAAAGGACACCTACGGAGCTCAACACGAGAACTACGATGATATTGAGATCGTATCAATGAAAATGCTGCAATATAACGATGAAAATGCACTTGGAATCGTAGTTCATCGAACAAACTTTGACAGTTGTACAATCAGTAAGTTCAAGTCACTAAGCATTAAAAAGCTGTTAGGACTTTTTGGGAACGTCACAATTTTTGAATCAACAGCAACACTTTTAGAAGTTAAGAAACAAATTAGAGATGAAGACATTCATCTGTGTCCAATGGACGTTAAAGGCTTTGTTGTTAAGACATTTGAACTT
Protein: 1008 (aa)
MKVNHSSLACNLNTNVIPEPDIQMLKTLNKLSFSNTDGGVWKQGFNITYDSNLWNSSRKLKVFIVLHSHNDPGWIYTFDEYYRQQTINIFKNMLKYLSKNSKLKFIWAEIVYFSKWYEGLPESVRQEVQKIVSNGQLEFVTGGWVMPDEAASHWYSVLLSLTEGQTWLKENLNVTNIKSSWAIDPFGHSSSFPFILKQAGFENLLIQRTHYSIKKYLAKRKQLEFRWQQLWDFKGNSEIFTHMMPFYSYDIPHTCGPDPKVCCQFDFRRSFCPWNVNPVEIDDTNILQKSKLLVDQWKKKSQLFRSKSLLTPVGDDFTYQSDWEWKVQTTNFEKLINFINKNVEFNVEVKFATLQEYFDSVKNETIDFPSLSGDFFTYADRDSHYWSGYFTSRPFYKQTDRILLNYLRTAEIFSTLANFRSIQTLNSYLKYARRALSIFQHHDGVSGTARDNVMQDYNNMMIQGIEKSKFVIQQAVYKLMTDAFNYIPDHTIKYFDFDDTHSAGDNNIEERRTIIIDTLEKFIIIQNSQAYDREEIVEFIIDSQHACITDVKGKSVDAQISPMWNFIGNNSFIEFENRKFRLIFKAKVSAFGITVYKVYKCKDCGSVKYAQVKIYSNSNYEISFDYAGRIQVLKPTQFSLKVADSSLNFQGNGLMQSALISGVFTSLNIEFMTYGTNYTKDQWSGAYIFLPDGPAKAINVSSITSPVVVIEGPLESSMTTNLTFINHTIILRSHSKAIEIRNIVDIRNMNNTEIIMRVNTMKIKNYNVFYTDLNGLQYVKRKILGLVPLQGNYYPVNSGIFIEDKKFRLSLFTATPLGGSSLDSGQIEVMQDRRHSHDDNRGLGQGVLDNRPVLNIFKLLIENRSECKQLDEKYQMAFLSREAYREQKGLLHPLHKLIFTRGENWNGVKDTYGAQHENYDDIEIVSMKMLQYNDENALGIVVHRTNFDSCTISKFKSLSIKKLLGLFGNVTIFESTATLLEVKKQIRDEDIHLCPMDVKGFVVKTFEL
| Type | Start | End | Length |
| CDS |
3222 |
3351 |
130 |
| CDS |
3413 |
3671 |
259 |
| CDS |
4522 |
4957 |
436 |
| CDS |
5017 |
5348 |
332 |
| CDS |
5424 |
7290 |
1867 |
| intron |
3352 |
3412 |
61 |
| intron |
3672 |
4521 |
850 |
| intron |
4958 |
5016 |
59 |
| intron |
5349 |
5423 |
75 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001655799 |
mannosidase alpha class 2a [Aedes aegypti] gb|EAT35901.1| mannosidase alpha class 2a [Aedes aegypti] |
0.0 |
| InterPro |
IPR011013 |
Glycoside hydrolase-type carbohydrate-binding |
|
| InterPro |
IPR011330 |
Glycoside hydrolase/deacetylase, beta/alpha-barrel |
|
| InterPro |
IPR013780 |
Glycosyl hydrolase, family 13, all-beta |
|
| InterPro |
IPR015341 |
Glycoside hydrolase, family 38, central domain |
|
| InterPro |
IPR011682 |
Glycosyl hydrolases 38, C-terminal |
|
| InterPro |
IPR000602 |
Glycoside hydrolase, family 38, core |
|
| Gene Ontology(BP) |
GO:0006013 |
mannose metabolic process |
|
| Gene Ontology(BP) |
GO:0005975 |
carbohydrate metabolic process |
|
| Gene Ontology(MF) |
GO:0043169 |
cation binding |
|
| Gene Ontology(MF) |
GO:0030246 |
carbohydrate binding |
|
| Gene Ontology(MF) |
GO:0004553 |
hydrolase activity, hydrolyzing O-glycosyl compounds |
|
| Gene Ontology(MF) |
GO:0015923 |
mannosidase activity |
|
| Gene Ontology(MF) |
GO:0008270 |
zinc ion binding |
|
| Gene Ontology(MF) |
GO:0003824 |
catalytic activity |
|
| Gene Ontology(MF) |
GO:0004559 |
alpha-mannosidase activity |
|
| Pfam |
PF07748.8 |
Glycosyl hydrolases family 38 C-terminal domain |
1.4e-47 |
| Pfam |
PF01074.17 |
Glycosyl hydrolases family 38 N-terminal domain |
3.9e-86 |
| Pfam |
PF09261.6 |
Alpha mannosidase, middle domain |
9.8e-21 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
| Gene ID |
| Pn.05350 |
| Pn.10333 |
| Pn.11002 |
| Pn.02242 |
Orthologous genes
| Species |
Gene ID |
| P. vanderplanki |
Pv.16127 |
| D. plexippus |
DPOGS214574PA |
| D. plexippus |
DPOGS202980PA |
| H. sapiens |
ENSP00000453140 |
| H. melpomene |
HMEL005692-PA |
| H. sapiens |
ENSP00000261483 |
| P. humanus |
PHUM025610-PA |
| P. vanderplanki |
Pv.12022 |
| H. sapiens |
ENSP00000452866 |
| A. aegypti |
AAEL004389 |
| P. vanderplanki |
Pv.02758 |
| H. melpomene |
HMEL009536-PA |
| D. plexippus |
DPOGS203031PA |
| P. humanus |
PHUM459490-PA |
| P. vanderplanki |
Pv.07248 |
| H. sapiens |
ENSP00000453341 |
| B. mori |
BGIBMGA012324-TA |
| N. vitripennis |
NV15211-PA |
| H. sapiens |
ENSP00000388221 |
| H. sapiens |
ENSP00000452813 |
| N. vitripennis |
NV15396-PA |
| T. castaneum |
TC009186 |
| A. mellifera |
GB10547-PA |
| A. gambiae |
AGAP004020 |
| P. vanderplanki |
Pv.14333 |
| H. sapiens |
ENSP00000452948 |
| H. sapiens |
ENSP00000453999 |
| A. gambiae |
AGAP004032 |
| H. sapiens |
ENSP00000353655 |
| A. aegypti |
AAEL011978 |
| P. vanderplanki |
Pv.05797 |
| T. castaneum |
TC014283 |
| D. melanogaster |
FBgn0011740 |
| S. invicta |
SI2.2.0_13340 |
| H. melpomene |
HMEL009534-PA |
| H. sapiens |
ENSP00000452631 |
| B. mori |
BGIBMGA012267-TA |
| D. melanogaster |
FBgn0026616 |
| P. vanderplanki |
Pv.07247 |
| H. sapiens |
ENSP00000394372 |
| C. quinquefasciatus |
CPIJ009720 |
| C. quinquefasciatus |
CPIJ003442 |
| A. mellifera |
GB19751-PA |
| M. musculus |
ENSMUSG00000038886 |
| B. mori |
BGIBMGA005142-TA |