MidgeBase gene description page [Pn.16427]

Outline

Link to gbrowse

Gene ID Pn.16427
Type Protein coding gene
Scaffold PnScaf38446
Start 6564
End 8152
Direction +

Sequence

Transcript: 1464 (bp)

 ATGGAAGACACACAAGTTTATGAAACGCAAAGCCAGGATATTTTCTATAGCTTGCCGGTTCAGGAAGAGCCAGCTATTTGGGCCAATTTGAGGCTTTTGAAAAAGTCAAACAAAATTTATTTTCTAACCGCTGATAATGTGCATATTGGCCGACGTATCGGCGAGAATACTGTGATCGATCAATTCATTACCATCGTAGAAAATGATTTTGAAAAGCAAGACGAATTTATGCGCATATCCAGCAATCACTTCGCTATCAAAAAAATGAGCCAAGATAGCACTGCAGTTGGATATCAAAATGTTAAGCCGCATGAACCTGCCTACATTGAGTGCATTGGACGGAATGGAGTCGTGGTAAATGGAGTCAAATTGCGCAGCGGTCAAATGATGCTTTTGAAAAACAACAGTATCATAGGATTTTCAAGCAGAAAACCTTTCTGCTGCTTCAAGTATGAGAACTCAAACGACAAAATCCTTCCTGAAAAATCCTACTTCTCCTGTAAGTATTCGGTCGGCAGAATGCTAGGCAAAGGCGGTTGTGGCGAGGTATATATCCTATACGACCTTGCAATCACTGATCGAGCGCAGTTCAAAACATATGCCTTAAAAACCATCGAATATTCAGATTCGAAAACGGTCCTGGACGGCGACGATGAGAATGAGACGTATTCGCAAGTTGTTAATGAAGTGAACCTTATGAAAAATTTGAATAATCATCATGTGATGAGAATTTTGGACCAAGATCGAAGCGATCGCTATCTCTTTATCGTCCTTGAATACATGTCAGGTGGCGACTTGCTTGGACGTATCATACAGCATTATCCGAAACAAAAGTTCATGCCAGAAAAAGACGCAAAATTCTTCTTTTATCAAATTCTCCTCGGCGTTAACTACATTCACTCTCAGAATGTCACTCATCGTGACATAAAACCGGAGAATATCATCCTTTCACACCGAGGAGATTCGCCTCTTGTAAAGCTTTGTGATTTCGGCTTGAGCAAGGGAAAGTCTGTTATGAAAACTGTCTGTGGAACTTTAATCTACTGTGCACCAGAAATAGTACTGGCCGAACCTCACTATACATACAAAGTTGACAACTGGTCTTTAGGCTGCCTTCTCTATGCCATGCTTAGCGGAAAAGTTCCATTTGGTGACGATGGAAACGTACGAAACAAGATAGTGAACGCTAATTACAACTTTAAATATCGGGAATTCAAAACGGTCTCTACCGCTGCCATTTCAATCATTCGCTTACTTCTCCAAAGAAGTCCCAAACATCGATGTGAAATCGATGAAATCTTAGCAAATAAGTGGATAACCGAGGACAGTTCAATCAAGGAAAGATTGAGTCAAGTTTACGACGAACACAATCTTGTGAACGATCTTGCAGACGATATGGAAAAGACTTTAATTCTAGACGACGACACCGAAATCCAACATGTTTCAAAAAGACCACGTGTGGGT 

Protein: 488 (aa)

 MEDTQVYETQSQDIFYSLPVQEEPAIWANLRLLKKSNKIYFLTADNVHIGRRIGENTVIDQFITIVENDFEKQDEFMRISSNHFAIKKMSQDSTAVGYQNVKPHEPAYIECIGRNGVVVNGVKLRSGQMMLLKNNSIIGFSSRKPFCCFKYENSNDKILPEKSYFSCKYSVGRMLGKGGCGEVYILYDLAITDRAQFKTYALKTIEYSDSKTVLDGDDENETYSQVVNEVNLMKNLNNHHVMRILDQDRSDRYLFIVLEYMSGGDLLGRIIQHYPKQKFMPEKDAKFFFYQILLGVNYIHSQNVTHRDIKPENIILSHRGDSPLVKLCDFGLSKGKSVMKTVCGTLIYCAPEIVLAEPHYTYKVDNWSLGCLLYAMLSGKVPFGDDGNVRNKIVNANYNFKYREFKTVSTAAISIIRLLLQRSPKHRCEIDEILANKWITEDSSIKERLSQVYDEHNLVNDLADDMEKTLILDDDTEIQHVSKRPRVG 
Type Start End Length
CDS 6564 6715 152
CDS 6777 7845 1069
CDS 7907 8149 243
intron 6716 6776 61
intron 7846 7906 61

Auto annotation result

Program/Analysis Accession Description Score/Expectation
BLASTP/NCBI-nr XP_001658430 serine/threonine-protein kinase chk2 (cds1) [Aedes aegypti] gb|EAT40742.1| serine/threonine-protein kinase chk2 (cds1) [Aedes aegypti] 2e-60
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR008984 SMAD/FHA domain
InterPro IPR002290 Serine/threonine- / dual-specificity protein kinase, catalytic domain
InterPro IPR020635 Tyrosine-protein kinase, catalytic domain
InterPro IPR000253 Forkhead-associated (FHA) domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
InterPro IPR011009 Protein kinase-like domain
Gene Ontology(BP) GO:0006468 protein phosphorylation
Gene Ontology(MF) GO:0004713 protein tyrosine kinase activity
Gene Ontology(MF) GO:0004674 protein serine/threonine kinase activity
Gene Ontology(MF) GO:0005524 ATP binding
Gene Ontology(MF) GO:0005515 protein binding
Gene Ontology(MF) GO:0004672 protein kinase activity
Gene Ontology(MF) GO:0016772 transferase activity, transferring phosphorus-containing groups
Pfam PF00069.20 Protein kinase domain 7.9e-61
Pfam PF06293.9 Lipopolysaccharide kinase (Kdo/WaaP) family 0.029
Pfam PF01636.18 Phosphotransferase enzyme family 0.023
Pfam PF07714.12 Protein tyrosine kinase 6.8e-30
Pfam PF00498.21 FHA domain 4.7e-07

Expression level (RPKM)

Paralog/Ortholog genes

Paralogous genes

Gene ID
Pn.04091

Orthologous genes

Species Gene ID
H. sapiens ENSP00000329012
B. mori BGIBMGA005370-TA
A. gambiae AGAP008341
T. castaneum TC015484
H. sapiens ENSP00000408065
H. sapiens ENSP00000372007
H. sapiens ENSP00000442458
A. aegypti AAEL007544
D. plexippus DPOGS211250PA
D. melanogaster FBgn0019686
H. sapiens ENSP00000329178
M. musculus ENSMUSG00000029521
H. sapiens ENSP00000404400
H. sapiens ENSP00000384835
H. melpomene HMEL012696-PA
S. invicta SI2.2.0_00480
H. sapiens ENSP00000372023
N. vitripennis NV12140-PA
P. humanus PHUM016570-PA
P. vanderplanki Pv.04697
A. mellifera GB14096-PA
H. sapiens ENSP00000384919
A. gambiae AGAP009784
H. sapiens ENSP00000385747
H. sapiens ENSP00000416721
C. quinquefasciatus CPIJ009147
H. sapiens ENSP00000386087
H. sapiens ENSP00000372021