MidgeBase gene description page [Pn.16418]
Outline
| Gene ID | Pn.16418 |
| Type | Protein coding gene |
| Scaffold | PnScaf38420 |
| Start | 7398 |
| End | 26440 |
| Direction | + |
Sequence
Transcript: 4311 (bp)
ATGGGCAATCAACAATCGGTTAAATCAAATGAGCCCAAAACAATTCCAAATCTTTCAATTCAAGGCCCAGTTCCATCTTCAATTCGGTCGAGCCGCTCTTCGAAATCTAGAGTCCCCAAAGATCCGAGGATATTAGGATCAAATATTTTCACTGAACACAATGAGGCATTATTACAATCTCGACCGCTGCCCCATGTGCCGCACAATCCAGTAGACGTTCTATGCCAAGAGAGTTCAGACCACAGCGGAACTTTACTATCGCAAGGAAGCAACACGAGCAACACACAGTCAACATTTGAAACAGCCAACAGATGGACATCCAAAGAGAATTTATTAACACCGGCACCGGAGGACGACGATCCGCAGTTGTTTGTGGCACTTTACGACTTCAAGGCTGGCGGAGAGAACCAACTGAGTCTGAGGAAGGGAGAGCAAGTTAGGATTCTTTCGTACAACAAGTCGGGCGAGTGGTGCGAAGCGCATTCCGACTCGGGACATGTCGGCTGGGTGCCCTCGAACTACGTTACGCCTCTGAACTCGTTGGAAAAGCACTCGTGGTATCACGGACCGATTTCGCGCAATGCGGCCGAGTATTTGCTGAGTTCGGGAATCAACGGGAGTTTTCTGGTGCGAGAGTCCGAGAGTTCGCCGGGTCAAAGATCAATAAGCTTGCGCTACGAGGGCCGAGTGTATCATTATCGCATCCAAGAGGATAACGATGGAAAGGTCTTCGTAACGGCAGAATACAAGTTCAACACGCTTGCCGAACTCGTTCACCATCACAGTGTTCTTCACGAGGGCCACGGACTAATTACGCCATTACTCTACCCGGCACCGAAGCAAAATAAACCCACAGTGTTTCCTCTCAGTCCAGAGCCAGATGAGTGGGAAATCAGCCGAACGGATATTGTTATGAAACATAAATTGGGCGGTGGACAATATGGGGAAGTTTACGAGGCAATTTGGAAGAGATATGGCAATACTGTCGCGGTAAAGACACTCAAAGAAGAGACGATGCCGTTTAAAGACTTCTTGGAGGAAGCGGCAATCATGAAGGAAATGAAGCATCCAAATCTAGTGCAATTGATTGGTGTGTGCACGCGAGAGCCACCTTTCTACATCATCACCGAGTTTATGAGTCACGGAAATCTCCTTGACTTTCTCCGCTCGGCCGGCCGCGAGACTTTGGATGCCGTAGCTCTCTTGTACATGGCGACGCAAATTGCTTCCGGCATGAGCTATTTGGAGAGTAGAAATTTCATACATCGCGATCTGGCGGCCAGAAATTGCCTCGTCGGCGAAAATAATCTCGTCAAAGTGGCCGATTTCGGGCTTGCACGCTTGATGCGCGACGACACGTACACCGCTCATGCCGGCGCGAAGTTTCCAATCAAATGGACCGCGCCCGAGGGACTGGCCTACAATAAATTTTCAACAAAGTCAGATGTGTGGGCTTTCGGCGTGCTTCTGTGGGAAATCGCAACATACGGAATGAGTCCTTATCCGGCCATCGATTTGACAGATGTTTACCATCGACTCGAGTCGGGCTACAGGATGGAGCGACCGCAAGGATGTCCCACCGAGGTTTATGAATTAATGAGGAAATGTTGGCAGTGGAATGCGGCAGATCGGCCAACATTCAAGAGCATCCATCACGATCTGGAGCACATGTTTCAAGAATCTTCAATCATTGAGGCTGTAGAGAAGCAGCTTCAAGGTACCGTGCCGCAGCAACCTAGTCTAACTCCTCAGATGAGTAAAAAGCCCCAAATGGGAACGCACGTCGTTCAACAGCACCAACAGCAACAACAACAGCAACAGCACGACCAGCAGGCAATTACACCACTGTCAGAAACTGGTTCATCATCAAAATTGAGCACTTTTTCATCCACTGGAAAAACAGGTTCGGCAGTGCAAATGAGAAGAACAACCAACAAGAAAGGAAAAACGGCACCGGCACCACCAAAGCGAACATCGCTGCTTTCGTCTAGTCGTGATTCTCAGTACCGAGAGGATGATGCAAGAAATATTGATGAGCTAAACGGTATGGGCTTTTCACGAGAAATTGCCAACTTAGCTTCGCGAGCTGATTCTGAAAATGAAAATCACGAGATAACGCCAGACACGGACACTGACAGCCAAGAGCATTTAGCAAAACACCAGATGATGCCGCCACCGCATACATCACAAACGGCTTTCAAACGAGCCCCAGTCATGGGAACGCGACTGGACGCTCGCAACAGCAAATCGAGATCGAGTCAACGAAAAACACCACTAGGAAATGCACCATTGAATCAGCAGCAACTGCAATCATCACAGCTGCAGCAACAGCAGCAGCAACAACAGCAACAGCAGACAGTCGTAGGAGCGCTCGAGGTTCAGAACGTGAAGCGTGCGATTAATCGCTATGGCACGTTGCCAAAATCGAGTCGCATTGGCGCTTATCTCGAGTCGTTACGACAAAACGGCGAGAATGAGTCACCGCAAATTGCTCAACAGCAGCAATTGAATACGGCCCAGGCGAACATTCTGGGCATTCCGACAGTCGAACAGTTGCCATCAACCCACTCGCCTCGTACTGCGCTAAAGATCCAACCGCAGATGATTCGTAGTAACTCATCGGGCGGTGTTACCATGACAAACTCTGCCACTGCTAGTCTCACAAAGCTGCAGCGACACCGAACGGCCACCGACGGCACAATGATGACCACATTCTCCAGCTTCAGAAGCACCGGAAGCAACAACAGTCCAAAGCGAACTATTCCAGTCTCCCTTGCCGAGTTGGAGTTCCCACCGCCGCCACCGCCAGAAGAGTTCGATGTCGTCAGCAATCAGCTTCACTCGTCAGACATTCCGATCAAAAGCCAGATCAACAACAATAACGACGTATCAAACACGGCGCCGAGCGTCGAAGAAGCCAGCACTCGCTTCGGCGTGAGTTTGCGAAAGCGCGAGCCATCGACTGACTCGTGCAGCTCACTCGGCAGTCCCGCAAACGACCTGAACGAATCATCACAAAAGTCACCATTCATGAGCAACAACAACAGCAGTGATTCTGTGCCAAAGTGCATCGATCCGGCCGCCATGCTCGTGTCGGAGTTGGCCGAGACCATGCACATTCCGAAACCAGATGCGCCCCTCAAGCCCTCCGAGCTGGCCAAGAAGCCAACCACGCCGAAACCAATTCTTCCAGCATCCGCGGCGTCCAGCGAGTCCAACGGCATTCCCTTCAAAGCACAACTGAAGAAGGTCGAGCCGAAGAAGGTGGCGAAGGAACAGCCAAAGGATGACATTACTACGAGTATAATTGATTTTAAGTCGCGACTACGCAAAGTCGAACACGCCGATGCCGAAAACACTTCCGATGACATTAATAAGCTTAACAACAAAAGTGATAGTAAAATAAGTGATGAATTAACATGCAACAGTAACAGCAACAACAACAACATCAACAACAGCAACAGCAAAATGAAACCAAATAATAATAACAATAATAGTGTTAGTAATAGTAATGCTACTAATAATACGAGCAGTAAAAAGACTGAAATCAAGATAGACGTAGCTGACGAGAAGAAGAGCAAGGAGAGCAATGGCGACAGCAAGCCACCACTGTCGTCGAGCGATGAGGATGATAAGCGAAAGAGCACCGGAAGCATAAGTAGCCTGAAGAAACTGTGGGAGGCGAAACCGTCCTCGAATGCTGCCAACGAGCACGCGAATCAACTGAGTCCAAAAATGGGGAGTGCAATCAAGAAGAAGGATGATTGCGACGACAACCACAACATTAGTACGTCGCCGAATGGCATGCACCAGCACGAAAGCAGCATGGAGCCGCCAGTCGCGAAGAAACCCGCCGTTCCGGTGAAACCATCGAAATTCACAATCTACGCGACTCCAATTCAACAGCAACAGCAGCAGAGCGTGAAGGCCGTCGAAAATAACAACCTCAACAGTGCGCTATCGAACGTCATGGCATCGGCCAATTCGGCATCGCCGGCGAGCCGCGAAAACATTCTCGAGCTCGTGCAGATGGTGGAGTGCAATTTAAAAATCCCAGTGAACTTGATAACTGCGACGCAGTGGCTTCAGTTGAGCGATAAATTGAACATTATACAGTCGTCGTGCGTCACATATGCCGACACGGAGACGATGCCTCCACACACAAAATTTCAATTTCGCGAGTTAGTCACCAGAGTCGAAAATCAATCAAACTGTTTGCGAACGGCCGGCCAGAAAAACGTTCAAGACAATGAGAAGTTGCTAATTGAAGTTGGTCAGTCGCTCAAACAGCTGTCGAATGCCTTACACAGG
Protein: 1437 (aa)
MGNQQSVKSNEPKTIPNLSIQGPVPSSIRSSRSSKSRVPKDPRILGSNIFTEHNEALLQSRPLPHVPHNPVDVLCQESSDHSGTLLSQGSNTSNTQSTFETANRWTSKENLLTPAPEDDDPQLFVALYDFKAGGENQLSLRKGEQVRILSYNKSGEWCEAHSDSGHVGWVPSNYVTPLNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRIQEDNDGKVFVTAEYKFNTLAELVHHHSVLHEGHGLITPLLYPAPKQNKPTVFPLSPEPDEWEISRTDIVMKHKLGGGQYGEVYEAIWKRYGNTVAVKTLKEETMPFKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNFIHRDLAARNCLVGENNLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHRLESGYRMERPQGCPTEVYELMRKCWQWNAADRPTFKSIHHDLEHMFQESSIIEAVEKQLQGTVPQQPSLTPQMSKKPQMGTHVVQQHQQQQQQQQHDQQAITPLSETGSSSKLSTFSSTGKTGSAVQMRRTTNKKGKTAPAPPKRTSLLSSSRDSQYREDDARNIDELNGMGFSREIANLASRADSENENHEITPDTDTDSQEHLAKHQMMPPPHTSQTAFKRAPVMGTRLDARNSKSRSSQRKTPLGNAPLNQQQLQSSQLQQQQQQQQQQQTVVGALEVQNVKRAINRYGTLPKSSRIGAYLESLRQNGENESPQIAQQQQLNTAQANILGIPTVEQLPSTHSPRTALKIQPQMIRSNSSGGVTMTNSATASLTKLQRHRTATDGTMMTTFSSFRSTGSNNSPKRTIPVSLAELEFPPPPPPEEFDVVSNQLHSSDIPIKSQINNNNDVSNTAPSVEEASTRFGVSLRKREPSTDSCSSLGSPANDLNESSQKSPFMSNNNSSDSVPKCIDPAAMLVSELAETMHIPKPDAPLKPSELAKKPTTPKPILPASAASSESNGIPFKAQLKKVEPKKVAKEQPKDDITTSIIDFKSRLRKVEHADAENTSDDINKLNNKSDSKISDELTCNSNSNNNNINNSNSKMKPNNNNNNSVSNSNATNNTSSKKTEIKIDVADEKKSKESNGDSKPPLSSSDEDDKRKSTGSISSLKKLWEAKPSSNAANEHANQLSPKMGSAIKKKDDCDDNHNISTSPNGMHQHESSMEPPVAKKPAVPVKPSKFTIYATPIQQQQQQSVKAVENNNLNSALSNVMASANSASPASRENILELVQMVECNLKIPVNLITATQWLQLSDKLNIIQSSCVTYADTETMPPHTKFQFRELVTRVENQSNCLRTAGQKNVQDNEKLLIEVGQSLKQLSNALHR
| Type | Start | End | Length |
| CDS |
7398 |
7560 |
163 |
| CDS |
21275 |
21984 |
710 |
| CDS |
22090 |
22227 |
138 |
| CDS |
22301 |
22748 |
448 |
| CDS |
22818 |
23035 |
218 |
| CDS |
23120 |
23294 |
175 |
| CDS |
23371 |
23494 |
124 |
| CDS |
23582 |
23655 |
74 |
| CDS |
24111 |
24869 |
759 |
| CDS |
24936 |
26437 |
1502 |
| intron |
7561 |
21274 |
13714 |
| intron |
21985 |
22089 |
105 |
| intron |
22228 |
22300 |
73 |
| intron |
22749 |
22817 |
69 |
| intron |
23036 |
23119 |
84 |
| intron |
23295 |
23370 |
76 |
| intron |
23495 |
23581 |
87 |
| intron |
23656 |
24110 |
455 |
| intron |
24870 |
24935 |
66 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001659488 |
proto-oncogene tyrosine-protein kinase abl1 [Aedes aegypti] gb|EAT39429.1| proto-oncogene tyrosine-protein kinase abl1 [Aedes aegypti] |
0.0 |
| InterPro |
IPR017441 |
Protein kinase, ATP binding site |
|
| InterPro |
IPR002290 |
Serine/threonine- / dual-specificity protein kinase, catalytic domain |
|
| InterPro |
IPR001245 |
Serine-threonine/tyrosine-protein kinase catalytic domain |
|
| InterPro |
IPR011009 |
Protein kinase-like domain |
|
| InterPro |
IPR015015 |
F-actin binding |
|
| InterPro |
IPR001452 |
Src homology-3 domain |
|
| InterPro |
IPR000980 |
SH2 domain |
|
| InterPro |
IPR000719 |
Protein kinase, catalytic domain |
|
| InterPro |
IPR008266 |
Tyrosine-protein kinase, active site |
|
| InterPro |
IPR020635 |
Tyrosine-protein kinase, catalytic domain |
|
| Gene Ontology(BP) |
GO:0006468 |
protein phosphorylation |
|
| Gene Ontology(MF) |
GO:0004713 |
protein tyrosine kinase activity |
|
| Gene Ontology(MF) |
GO:0004715 |
non-membrane spanning protein tyrosine kinase activity |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0004672 |
protein kinase activity |
|
| Gene Ontology(MF) |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
|
| Pfam |
PF00069.20 |
Protein kinase domain |
2.4e-51 |
| Pfam |
PF07653.12 |
Variant SH3 domain |
2.4e-09 |
| Pfam |
PF00017.19 |
SH2 domain |
2.2e-25 |
| Pfam |
PF01636.18 |
Phosphotransferase enzyme family |
0.12 |
| Pfam |
PF07714.12 |
Protein tyrosine kinase |
3.4e-99 |
| Pfam |
PF00018.23 |
SH3 domain |
8.1e-13 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000361423 |
| H. sapiens |
ENSP00000427562 |
| T. castaneum |
TC002481 |
| N. vitripennis |
NV17221-PA |
| H. sapiens |
ENSP00000323315 |
| H. sapiens |
ENSP00000426831 |
| H. melpomene |
HMEL015066-PA |
| C. quinquefasciatus |
CPIJ009602 |
| C. quinquefasciatus |
CPIJ003985 |
| H. sapiens |
ENSP00000356595 |
| D. melanogaster |
FBgn0000017 |
| P. vanderplanki |
Pv.00384 |
| A. aegypti |
AAEL008777 |
| H. sapiens |
ENSP00000386152 |
| H. sapiens |
ENSP00000423578 |
| M. musculus |
ENSMUSG00000026842 |
| M. musculus |
ENSMUSG00000026596 |
| A. gambiae |
AGAP004989 |
| H. sapiens |
ENSP00000424697 |
| A. mellifera |
GB11301-PA |
| P. humanus |
PHUM538010-PA |
| D. plexippus |
DPOGS200085PA |
| H. sapiens |
ENSP00000339209 |
| H. sapiens |
ENSP00000423413 |
| H. sapiens |
ENSP00000375897 |
| B. mori |
BGIBMGA002069-TA |