MidgeBase gene description page [Pn.15638]
Outline
| Gene ID | Pn.15638 |
| Type | Protein coding gene |
| Scaffold | PnScaf32145 |
| Start | 9282 |
| End | 14678 |
| Direction | + |
Sequence
Transcript: 4587 (bp)
ATGGATCATCACCATGTAATCAAGAACTTGACAGGCTATACTACAGTTTTGGATGATGATAACATTACCACAACGCGTCCAGATTTATATCAAAAGTGCAATCGAAATTCTCATTCAAGTTGTCATTCAAGCGATACGAGCTCCGCCTACAGTGGCTCAGACACAATGACATCCATTCACAGTTCATCAATCGATGCGGAGGAGGTTGATTTGTCGGGACTCATTGAGTCCGTGGTCGACAGCGATGAGGAGGACCTCGCCGAGTCGATGGAGAGCGCCAACATTCGTGACACAGTACGCGATTGCCTTGAAAAGGATCCCTCCGAGAGAAGCGAGAGTGACATTGAAGTGCTTCTCGGTTTCACGCAAAACCTGAAGGCATTTACTAATATGACGCTGACAGTGAGACGTGCTTTATGTTCTGTGATGGTCTTTGCTGTGGTTGAAAAAATGGGCACAGTTGTAATGAAAGATTGTGAAGAATTGGATTCGTGGAGTGTCCTTATAAATGGCGTAGTTGAGATCGAACATCCCGGTGGTGCTACACAACAGCTACATTATGGCGATTCATTTGGAATTGCTCCAACAATGGAAAAGTCATATCATAATGGTATCATGAGAACAAAAACAGATGACTGTCAATTTGTTTGCATTACACAAGCTGATTACTATCGTATCCTTCACGAAGGCGAAGGTAACATACGGAAGCACGAGCAAGACGGAAAGGTTGTTATTGTTACGGAGCTACGAAAGACCGATACGGCCGGAAAGCGTGAGCCCGTCGTCATTCAGGGCACGCCCGAGCGCTTGATGCTTCACTTGATCGAAGAAAACTCAATAAACGATCCCACATACGTTGAGGACTTTCTCTTGACGCATAGAACTTTCATCGATACACAAATTCGCGTAGCAAATCAGTTGCTCGAGTGGTTTCGCTCCGATGAGATTGTGGATGATCTCAAGCCGCCCATTTCGGAAGGCTCCTCTGCCGCTACGCCGTCCTACATCGACGTAAAATATCGTGTTGCACGCGTTGTTATCTTATGGGTGAACAATTACTTCACCGATTTCGAAACGGATGCTCAAATGATGGAGTTTCTTGAGGTTTTCGAGTCAGAATTGGAGAAGCACAGTATGTTGGAGGAACTCAAATTGCTGCATGTCGCGCACACACACAAGGCGCGTACGCGAACAATTACGCTAACGAGAAGTTCGCGCGACGAGAGCTTGCATTTTAAAATAATTGGCGGCTATGAGAAGGGCGGCGGAATTTTCATCTTCGAAATTGACAAGAACTCGAAGGCAAGTGATATGGGCTTGCGTCGAGGCGATCAAATACTCGAGGTTAATGGTCATAATTTCGAGCACGTTACACACGCGAGAGCAATGGAAATTTTAACTGGAACAACTCACTTGAGCATTGCAGTGAAAAGCAATTTGCTCGTGTTTCGTGAGCTCCTCCACTCGACGAACAAAAATTCGCCACGGCTCAAGACGAAAATGAAAATTGCCTCGGATCTGGCGAAGCTGCAGGCGACAGACACTCGAGTTCGACTCTCGTCGGTAGATCTGCTGACGTCCAGCCATGACGTCACAGACAACGTGATGGACCCGCTTCTCAAGTATTCGAATGCATTCTCGAAGCAACCGATGATGACACCAACAAAGTTCAGTAATAGCGAATCGGCGCACGGAAAAGTCGCGAGTCTCATGAACCATCACAAGAACAGCTTCCTCACGCTGGGACCAAAGAAAAAGATACAGAAGGCACTCCAGAAACTGAATCTATTACCAAAGAATAATTCACTCATGGATTCATCGAGTGGCGGTGGAAGTGCTGCAGCGGCTGCTGCTGCCGCCATCACAAACGACGAGGACGACGCAAGCAGCGGCTTTTTGACGGGCACAACAGTGTCATCGTCGTCGTCGTCTTCGTCGACGATCAGCAAGAATGTCGTCAATCAGCAGCAACACGGTGCAGAAAGTGGCACAACATGTGGCGCTGACACAGACTCGAATCTCGATGTGAACGCAGATGACGGCGAGTTGCTGTGCGATGATGAGAAAGAGGAGCACCACGAGCACGAATTCAATAATAATCGCCAATCGATTACTGCTTCGACCACAACAATTACGACCATGACATCTGTTTCGTCGAGCGGAAGTGCGGGAACGTCGGCGAGCACGAACACCAACTTTTACTCGCACCCCGACAGTCACCAGCAGCAAGAGATGGCCATGTTTTACGACGATATTCGAACGGCAGATTATCCGGAGCACGTATTGAAGGTCTTTAAGCCAGATCAGACCTACAAGTTTCTACTGATACACAAAGAAACAACGGCACATGAAGTCGTAATGCTGGCGCTGCAAGAGTTCGGCTCACATGAGCCAAGCAATAACTTTTCACTGTGCGAAGTTAGTGTTAGTGAAGGCGGCATGATAAAGCAAAGAAGATTGCCCGAGCAATTACAAAATCTCGCCGATCGCATCGGATTAAGCTCGCGTTATTATTTGAAAACGAATGGAATAACTGAAACGCTCGTGCCCGACGAAATGGCATCTGACTTGGTGCGCGAAAATATCGTTCATTTTCTTCAATTGAATCCCAATGAGATTGCCATTCAGCTCACACATCAAGACTTTCAAATTTTCCGTCAAATCGAGTCGACCGAGTACATTGATGACTTATTCATTATCAAAAGCAAATACGGTACGCCTATGTTGAACAAGTTCGCAGAGCTCGTTAATAACGAGATGTTTTGGGTGGTGAGCGAAATTTGCAAGGAGACGAATATCGTGCGGCGAATGAAGATAATTAAGCAGTTCATTAAGATTGCGCGCCACTGTAAAGACTGCAAGAACTTTAACTCGGTGTTCGCAATTATCTCGGGACTGGGTCACGCATCAGTTTCGCGTCTCCGACTGACGTGGGAAAAATTGCCGAGCAAATATCAAAAGCTGTTCAATGACTTGCAAGAGCTGATGGATCCGTCGAGAAACATGAGCAAATATCGTCAGTTGGTCGCAATGGAGATGTCGCAGAAGCGCTCGCTAATTCCCTTCTATCCCGTCGTGAAGAAAGATTTGACTTTCATACATCTCGGCAACGACACCCGCATCGAGGGTCTGATAAATTTCGAGAAGCTCCGCATGATATCGAAAGAAGTGCGAAACCTAATGGATATGTGCAGCTCGCCGACGCCATACATGGACAACATTCTCAACATGCTCGACATCAAGAACCAGCCGAACGCAGCTATATCTGCACTCAATCAAATCACGACCTCAATCGGCCACACGCTGGCTGCCAACATCATTCAGCACGGGTCGGCGACAGTCAAGAGACGAAAGAAGTCAGCGCAAGCACCAAATCCAAAGAAAATGTTCGAAGAGGCTCAAATGGTTCGTCGCGTCAAAGCGTACCTGAACAATATTCAAGTCATAAAGGACGAGGAGAAGCTCCACATTATGTCGCTCGAGTGCGAGCCCGCCATCGTCGTTTCGGCCCCGAACTCCGTAACGATTCGCAAGCGCCATCCATCGCCCACGCTCTCGACCACGAGCAGCACGAGCTCGAAGAGCGAGGGCATGAAAAATGTCGGACCGAAATTCGGCACAGCTTCGCCGCAGGCAGTGAAGAAGATTCTCTCGCTCGCCGAGAATTCAAAGACTCGACCGCATCAGTCGCGACATTTGGGCATGAATCTTCCGCACGGTGCTCTACCATACTCGCATAATCTTCAGCATGCAAATCTAAGTCCCTCACCTTCGCCGGGCTCGCATCGACGAATTGCTTCGGCAGCCGGTGGCTCAGCAGCTTGGCAGCCCACGCTGCATTGCTTTGCACCGCCAAACGTTGGAAAGTTTGTGCATGAACGCTCGCATTCTGATACGCCAAATCCACTACCGTTACCGTCAGTCGATCTATCAGCCGAAAGCAGTTCGGTGACATCACTCAGCAATTTGCCAATAAGAAAGACTACGCACGGCTCCATATCGTCAACCGATAGTGGGCACAGCGACGCGATGAGCTATTGCGATCCTCCGTCGAACGTTTATCACTTGCAGCAGACGCAATCGACAATGGCCGCTCCATTGCCGCCTCGAAGGCACTCAGCAGTGCAGCAAGGAACAAACAATACGAATTTATACCAATTCCAGCCAAATAACGTTAACAGTACAAGTACAAAGCAAGCAAACGGAGATTTAGCGTCGATGCCGCCACCTCCAAATCCACGAACACGTCCTCCTCCCTTTCAGCCGATAGGCATTCCCGTTCTGCCAAATGCAGGCATCAATGTCGGCGCAAATGTTGCGGGCTACAACATTTACACATCACAGCAGCAGCAATATCAGCAATTGAGGCACACTGGAATGATTCCGTCACCTCCGCCAAGAACAAATCAGCAGCAACAACAGCAGCGTTACCATCACCCACAATCTCACAATCTAACAGAAATGGCACGGCTACACCGAATCGGCAGAGCGTATTCGCACGAAGGTGTCATTGAATCATCGTTAGGCGATATTGACATTTATTATCCCGATGAAGATGATGATGACGAGACACAAGTGTCTGCTGTT
Protein: 1529 (aa)
MDHHHVIKNLTGYTTVLDDDNITTTRPDLYQKCNRNSHSSCHSSDTSSAYSGSDTMTSIHSSSIDAEEVDLSGLIESVVDSDEEDLAESMESANIRDTVRDCLEKDPSERSESDIEVLLGFTQNLKAFTNMTLTVRRALCSVMVFAVVEKMGTVVMKDCEELDSWSVLINGVVEIEHPGGATQQLHYGDSFGIAPTMEKSYHNGIMRTKTDDCQFVCITQADYYRILHEGEGNIRKHEQDGKVVIVTELRKTDTAGKREPVVIQGTPERLMLHLIEENSINDPTYVEDFLLTHRTFIDTQIRVANQLLEWFRSDEIVDDLKPPISEGSSAATPSYIDVKYRVARVVILWVNNYFTDFETDAQMMEFLEVFESELEKHSMLEELKLLHVAHTHKARTRTITLTRSSRDESLHFKIIGGYEKGGGIFIFEIDKNSKASDMGLRRGDQILEVNGHNFEHVTHARAMEILTGTTHLSIAVKSNLLVFRELLHSTNKNSPRLKTKMKIASDLAKLQATDTRVRLSSVDLLTSSHDVTDNVMDPLLKYSNAFSKQPMMTPTKFSNSESAHGKVASLMNHHKNSFLTLGPKKKIQKALQKLNLLPKNNSLMDSSSGGGSAAAAAAAAITNDEDDASSGFLTGTTVSSSSSSSSTISKNVVNQQQHGAESGTTCGADTDSNLDVNADDGELLCDDEKEEHHEHEFNNNRQSITASTTTITTMTSVSSSGSAGTSASTNTNFYSHPDSHQQQEMAMFYDDIRTADYPEHVLKVFKPDQTYKFLLIHKETTAHEVVMLALQEFGSHEPSNNFSLCEVSVSEGGMIKQRRLPEQLQNLADRIGLSSRYYLKTNGITETLVPDEMASDLVRENIVHFLQLNPNEIAIQLTHQDFQIFRQIESTEYIDDLFIIKSKYGTPMLNKFAELVNNEMFWVVSEICKETNIVRRMKIIKQFIKIARHCKDCKNFNSVFAIISGLGHASVSRLRLTWEKLPSKYQKLFNDLQELMDPSRNMSKYRQLVAMEMSQKRSLIPFYPVVKKDLTFIHLGNDTRIEGLINFEKLRMISKEVRNLMDMCSSPTPYMDNILNMLDIKNQPNAAISALNQITTSIGHTLAANIIQHGSATVKRRKKSAQAPNPKKMFEEAQMVRRVKAYLNNIQVIKDEEKLHIMSLECEPAIVVSAPNSVTIRKRHPSPTLSTTSSTSSKSEGMKNVGPKFGTASPQAVKKILSLAENSKTRPHQSRHLGMNLPHGALPYSHNLQHANLSPSPSPGSHRRIASAAGGSAAWQPTLHCFAPPNVGKFVHERSHSDTPNPLPLPSVDLSAESSSVTSLSNLPIRKTTHGSISSTDSGHSDAMSYCDPPSNVYHLQQTQSTMAAPLPPRRHSAVQQGTNNTNLYQFQPNNVNSTSTKQANGDLASMPPPPNPRTRPPPFQPIGIPVLPNAGINVGANVAGYNIYTSQQQQYQQLRHTGMIPSPPPRTNQQQQQQRYHHPQSHNLTEMARLHRIGRAYSHEGVIESSLGDIDIYYPDEDDDDETQVSAV
| Type | Start | End | Length |
| CDS |
9282 |
9344 |
63 |
| CDS |
9500 |
9911 |
412 |
| CDS |
10003 |
13338 |
3336 |
| CDS |
13452 |
13584 |
133 |
| CDS |
13726 |
14156 |
431 |
| CDS |
14302 |
14484 |
183 |
| CDS |
14647 |
14675 |
29 |
| intron |
9345 |
9499 |
155 |
| intron |
9912 |
10002 |
91 |
| intron |
13339 |
13451 |
113 |
| intron |
13585 |
13725 |
141 |
| intron |
14157 |
14301 |
145 |
| intron |
14485 |
14646 |
162 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001962294 |
GF14515 [Drosophila ananassae] gb|EDV31515.1| GF14515 [Drosophila ananassae] |
0.0 |
| InterPro |
IPR000595 |
Cyclic nucleotide-binding domain |
|
| InterPro |
IPR008937 |
Ras guanine nucleotide exchange factor |
|
| InterPro |
IPR001478 |
PDZ domain |
|
| InterPro |
IPR023578 |
Ras guanine nucleotide exchange factor, domain |
|
| InterPro |
IPR018490 |
Cyclic nucleotide-binding-like |
|
| InterPro |
IPR019804 |
Ras guanine-nucleotide exchange factor, conserved site |
|
| InterPro |
IPR014710 |
RmlC-like jelly roll fold |
|
| InterPro |
IPR001895 |
Guanine-nucleotide dissociation stimulator CDC25 |
|
| InterPro |
IPR000651 |
Ras-like guanine nucleotide exchange factor, N-terminal |
|
| InterPro |
IPR000159 |
Ras-association |
|
| Gene Ontology(BP) |
GO:0007165 |
signal transduction |
|
| Gene Ontology(BP) |
GO:0007264 |
small GTPase mediated signal transduction |
|
| Gene Ontology(BP) |
GO:0051056 |
regulation of small GTPase mediated signal transduction |
|
| Gene Ontology(CC) |
GO:0005622 |
intracellular |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
| Pfam |
PF00027.24 |
Cyclic nucleotide-binding domain |
0.00038 |
| Pfam |
PF00788.18 |
Ras association (RalGDS/AF-6) domain |
3.6e-10 |
| Pfam |
PF00617.14 |
RasGEF domain |
1.1e-62 |
| Pfam |
PF13180.1 |
PDZ domain |
0.0014 |
| Pfam |
PF09175.5 |
Domain of unknown function (DUF1944) |
0.0079 |
| Pfam |
PF00595.19 |
PDZ domain (Also known as DHR or GLGF) |
1.7e-10 |
| Pfam |
PF00618.15 |
RasGEF N-terminal motif |
1.7e-18 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| D. melanogaster |
FBgn0021873 |
| H. sapiens |
ENSP00000296859 |
| H. melpomene |
HMEL004725-PA |
| T. castaneum |
TC003942 |
| H. sapiens |
ENSP00000309298 |
| S. invicta |
SI2.2.0_13342 |
| C. quinquefasciatus |
CPIJ005470 |
| M. musculus |
ENSMUSG00000062232 |
| P. humanus |
PHUM596850-PA |
| A. aegypti |
AAEL005643 |
| H. sapiens |
ENSP00000425389 |
| A. mellifera |
GB20093-PA |
| D. plexippus |
DPOGS202280PA |
| B. mori |
BGIBMGA004936-TA |
| H. sapiens |
ENSP00000264431 |
| H. sapiens |
ENSP00000426910 |
| H. sapiens |
ENSP00000426948 |
| H. sapiens |
ENSP00000426081 |
| H. sapiens |
ENSP00000425772 |
| H. sapiens |
ENSP00000421684 |
| M. musculus |
ENSMUSG00000037533 |
| N. vitripennis |
NV15063-PA |
| H. sapiens |
ENSP00000311419 |
| A. gambiae |
AGAP009261 |
| P. vanderplanki |
Pv.17566 |