MidgeBase gene description page [Pn.14553]
Outline
| Gene ID | Pn.14553 |
| Type | Protein coding gene |
| Scaffold | PnScaf24815 |
| Start | 12443 |
| End | 14325 |
| Direction | + |
Sequence
Transcript: 1296 (bp)
ATGTCCAAGCCTGCCTACAAAGTCGCTGATATCAGTCTCGCCGACCTCGGTCGCAAAGAGATCATCATTGCGGAAAACGAGATGCCCGGTCTGATGGCCATCCGCAAGAAGTATGGACCGCTGAAGATCTTGAAGGGCGCTCGCATTGCTGGCTGCTTGCACATGACCGTTCAGACAGCCGTCCTCATCGAGACTCTCCTCGAGTTGGGCGCTGAGGTTCAATGGAGCAGCTGTAATATTTTCAGCACGCAAGACTCAGCTGCGGCTGCTATCGCAAAGCGCGGTGTCCCCGTTTACGCATGGAAGGGCGAGACGGAGGAGGAGTACTTGTGGTGCATCGAGCAGACGCTCGTCTTTCCCAACGGCGAGCCGCTCAACATGATCCTCGACGATGGCGGCGACCTCACGAATCTCGTGCACGAAAAATACCCGCAATACCTGACCGGCATCAAGGGCATCAGCGAGGAGACGACGACCGGTGTCCACAATCTCTACAACATGTTCAGAGAGGGCAAACTGAAAGTTCCCGCCATCAACGTCAACGACTCGGTCACCAAGAGCAAGTTTGACAACCTCTATGGCTGCCGCGAGTCGCTCATCGACGGCATCAAGCGCGCCACGGACGTCATGATTGCAGGAAAGGTCTGCGTCGTTGCCGGCTACGGAGATGTTGGCAAAGGCTGCGCTCAGGCACTTCGATCGTTCGGCGGTCGAGTGATCGTCACTGAGATCGATCCGATCAATGCACTGCAAGCCGCCATGGAGGGCTACGAAGTCACGACCATGGACGAGGCAGCTAGCGAGGGAAACGTCTTCGTCACCACCACCGGATGCACAGACATCATCATGGGCGAGCACTTTTTGAAGATGAAAGACGACTCGATTGTGTGCAACATCGGGCACTTTGATTGCGAAGTCAACGTCGCGTGGCTCGATCAGAACGCAAAGGAAAAGATCAACATCAAGCCTCAGGTGGACCGATTTTTGCTCAACAACGGACATCACATTATTCTGTTGGCTGAGGGCAGACTCGTCAATCTCGGTTGCGCAAAGGGCCATCCCTCGTTCGTCATGTCAAACTCTTTCTCGAACCAGACTTTGGCTCAGATCGAGTTGTGGACAAAAGGCGACAAGTACCCGGTCGGAGTTCACATGCTGCCGAAGAAGCTCGACGAGGAAGTTGCCGCTCTTCACCTCGAAAAACTCGGAGTCAAACTCACGAAGCTGTCGGAGAAGCAGGCCAAGTACCTCGGCTTGTGCGCCGATGGCCCGTTCAAGCCCGACTACTACCGCTAC
Protein: 432 (aa)
MSKPAYKVADISLADLGRKEIIIAENEMPGLMAIRKKYGPLKILKGARIAGCLHMTVQTAVLIETLLELGAEVQWSSCNIFSTQDSAAAAIAKRGVPVYAWKGETEEEYLWCIEQTLVFPNGEPLNMILDDGGDLTNLVHEKYPQYLTGIKGISEETTTGVHNLYNMFREGKLKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVCVVAGYGDVGKGCAQALRSFGGRVIVTEIDPINALQAAMEGYEVTTMDEAASEGNVFVTTTGCTDIIMGEHFLKMKDDSIVCNIGHFDCEVNVAWLDQNAKEKINIKPQVDRFLLNNGHHIILLAEGRLVNLGCAKGHPSFVMSNSFSNQTLAQIELWTKGDKYPVGVHMLPKKLDEEVAALHLEKLGVKLTKLSEKQAKYLGLCADGPFKPDYYRY
| Type | Start | End | Length |
| CDS |
12443 |
12467 |
25 |
| CDS |
12725 |
12915 |
191 |
| CDS |
13243 |
14322 |
1080 |
| intron |
12468 |
12724 |
257 |
| intron |
12916 |
13242 |
327 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001659155 |
adenosylhomocysteinase [Aedes aegypti] gb|ABF18417.1| S-adenosyl-L-homocysteine hydrolase [Aedes aegypti] gb|EAT39891.1| adenosylhomocysteinase [Aedes aegypti] |
0.0 |
| InterPro |
IPR020082 |
S-adenosyl-L-homocysteine hydrolase, conserved site |
|
| InterPro |
IPR000043 |
Adenosylhomocysteinase |
|
| InterPro |
IPR015878 |
S-adenosyl-L-homocysteine hydrolase, NAD binding domain |
|
| Gene Ontology(BP) |
GO:0006730 |
one-carbon metabolic process |
|
| Gene Ontology(MF) |
GO:0004013 |
adenosylhomocysteinase activity |
|
| Pfam |
PF00670.16 |
S-adenosyl-L-homocysteine hydrolase, NAD binding domain |
9.1e-86 |
| Pfam |
PF05221.12 |
S-adenosyl-L-homocysteine hydrolase |
4.1e-229 |
| Pfam |
PF02826.14 |
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
3.7e-08 |
| Pfam |
PF07991.7 |
Acetohydroxy acid isomeroreductase, catalytic domain |
3.7e-05 |
| Pfam |
PF02254.13 |
TrkA-N domain |
0.00017 |
| Pfam |
PF00389.25 |
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain |
0.0068 |
| Pfam |
PF00208.16 |
Glutamate/Leucine/Phenylalanine/Valine dehydrogenase |
0.01 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| S. invicta |
SI2.2.0_11592 |
| A. aegypti |
AAEL008341 |
| A. mellifera |
GB14324-PA |
| C. quinquefasciatus |
CPIJ008116 |
| T. castaneum |
TC014564 |
| D. plexippus |
DPOGS211094PA |
| D. melanogaster |
FBgn0014455 |
| H. sapiens |
ENSP00000442820 |
| H. sapiens |
ENSP00000217426 |
| A. gambiae |
AGAP000719 |
| B. mori |
BGIBMGA011168-TA |
| P. humanus |
PHUM137320-PA |
| M. musculus |
ENSMUSG00000048087 |
| H. melpomene |
HMEL012478-PA |
| P. vanderplanki |
Pv.14725 |