MidgeBase gene description page [Pn.13580]
Outline
| Gene ID | Pn.13580 |
| Type | Protein coding gene |
| Scaffold | PnScaf20367 |
| Start | 173 |
| End | 12208 |
| Direction | - |
Sequence
Transcript: 3318 (bp)
ATGAATCAGCACATAAGCTCGATGCTCGAGCACTTCTCGTCATTAAGACGAAAGAACTCGGAAAGTGCACAGACATCGTCGAGTGATAAGCAAAATGCCACTGCCACGGCTCATCGTGAAATTGACCAGAAGGACGTGGGCGCCGACGTTGAGACGATGAGCAGCAAGACGAAGAGTATCCTGAAGGACCTCATGAGCGAGAACGGAGCCACCAATATCCTCCAGAATCTGAACATTTTAAAGTGCAACACTCCGTCGTCGCCGGCCTCAACGAATGGCACATGCAAGAAGCAACAGACGAGCAACAACAACGGCCATCAGCGAGCGACAAATTTTCTGCTTCCGACCACGAACGAGACCGAAAATGTTCACAACAAAAAGAGAAACAGCATCGCTGCGGTGACAGCGAACGGCGGTTGCGATTTGAACGTTCTAAGAGAAATGTCGCCGTCTCCGCAGCGCATGCATCGGAAATCATCGCACGACATTCGATTGCTGCGAAATCATATGCAGGACGGTGAGAAATCTACAGCTGTGCGACCGCTCAAAACGAAGAACATTTTAACGAAAAACGAAACGTTCGATACACTTCATTATCGTGGAATGGATGCTTTAGGATGCTCACCGCAAGTGTGCATGGGAAGTGTGATGTTCGGCAATGTCATGTCGACGGAAGTGCGGAAGCCAACAGTCATTAGAGAACACGCCATAGACTTCATCAGTCAGTATTATACGTCGATTAGGAGATTCAATTCGCCGGCACATCAAACGAGAATACAACAAATTGAGAAGGAAATTCAAGAGACGGGAGCATATCAATTAAGCGACTCGGAACTAATCTTCGGCGCGAAGACTGCATGGCGAAACTCCGCCCGATGCATCGGCAGAATCCAGTGGTCCAAGCTGCAGGTATTCGATTGCCGACATCTTCTGACGCCGTCGCAAATGTTCGAGGCATTGTGCAATCACATTAAGTACAGCACGAACAAGGGAAATTTGAGGTCGGCAATCACAATATTTCCGCAGAGAGTAGCAAACAGGCCAGATTTCCGCATTTGGAATTCACAGCTGATATCATATGCCGGCTATCTCAATGCAGACGGAACGATCACCGGCGACCCTTTGAACGTCGAAATAACAGATGTCTGCATAAAGCTGGGATGGACGAGTCCGAGGGGAGAGTTTGACATCTTGCCATTAGTGCTGTCGGCAAATGGACACGATCCCGAAATGTTTGAGTTTCCACCTGGCTTAGTATTGGAAGTTCCACTGACACATCCCCAGTTCACCTGGTTCGCTGAGATGAATCTGAAGTGGTACGGTGTTCCGGCTGTTTCAAGTATGCTCTTCGATTGCGGTGGGATTGTGTTTCCCAGCGTCGCCTTCTCAGGATGGTACATGTCGACTGAAATCGCATGTCGTGACCTGTGCGACTCGAATAGGCGAAATTTAATTGAGCCAATTGCAATCAAAATGGGTTTAGACGTCCGAAATCCAAGCTCATTATGGAAGGATAAGGCACTTGTCGAAATCAATATTGCAGTGCTGCACTCATACCAGACGCACAACATCACCATTGTGGACCATCATACGGCCAGCGAGAGCTTCATGAAGCACTACGAAAACGAGTGCAAAGTGAGGGGCGGCTGTCCGGCCGATTGGGTGTGGATTGTGCCACCGATGTCAGCCTCAATTCTGCAAGTCTTTCACCAAGAAATGGCAACATACTATCTCCGACCGTCGTTCGAGTATCAAGAGCCAGCAATGAAGACACATGTTTGGAGCAAGGGACGAGATTCGTCGAAGAATAAGTTGCCACGGAGGAAATTTCATTTTAAACAGATTGCGAGAGCCGTGAAGTTTACAAGCAAACTGTTTGGCCGTGCACTGAGCAGAAGAATAAAAGCGACTGTTCTGTACGCCACCGAGACGGGAAAGTCGGAGCAATACGCGAAGCAACTTGTTGAGCTACTTAGTCACGCGTTCAATGCACAGTTGTACGATATGGCCGAGTACGATATTTCATCAATTGAGCACGAGGCGCTGTTGCTAATTGTGGCATCGACCTTCGGTAACGGTGATCCGCCCGAAAATGGCGAGCAATTTGCACAGGGACTCTATGCGATGAAGCTGCACGAAGCCGAGGAGATGGAGGTTAATAACACGAATATTGCGGCATCATCAAAATCATTCATAAAAGTGAACTCTCGAACGGAGAGGAAGAAGAGTCAGCCGAAAATCGATAGATTAGACTCGTTGAGAGGCTCTTGCTCGGATTCGCTTTTTAATGAGACGTTTGGCAAATTGTCCAATGTTAGATTTGCAGTGTTCGCTCTTGGCTCATCGGCATACCCGAACTTCTGCTCGTTCGGGAAGTTTGTCGATAATCTCCTGGGCGAATTGGGCGGCGAAAGACTTATGAAAATCGTTCTCGGTGATGATTTGTGTGGTCAAGAGCACGAGTTTCGGAAATGGGCTTGTGATGTTTACAAAAAGTCTTGTGAAGTGTTTTGCCTCGATCTCAACGACGTTTGCGAGATGTCTTTAAAAGGCGAAGCATTGACGAAGGAGAATACGCGATTTCAAGCTGTTCGCGATGCCAACACGCCTCTCAACGTTCTGCTGAGCAAATACCACAATAAGAAGGTTCACGCGTGCAGAGCGAAAAGCAAGCCGATAAATTTACATGGCATGGCGGAGAAAAATACGATTCTTTTGGAAATTTTAATAGACGACCTTGTAAATTACGAGCCCGGCGACCACGTTGGTGTTTGTGCGATGAACCGGAAAGAGTACGTTGACGGAATTCTGGAAAAGCTGACGGGTGTGAGTGACTTCGATGAACCCCTGCAGCTGCAAGTCCTGAACGAGCAGCACACGGCCAACGGTCTCATAAAGACGTGGGAAAATCACGAGAAAATTCCAGTGTGCTCCCTCCGGACGCTGTTGACACGCTTTCTCGACATCACCAGTCCGCCGTCGCGACAATTTCTGACGTTTCTTCTGGCCCATTGCGAGGACTTTAAGGACAAGGAGCGGATGCGGACTCTCGTCAATGATTCGGCCGCCTACGAGGACTGGCGTCACAACAAGTTGCCTCACCTGCTCGAGGTCTTCGAGGAGTTTACGTCGTGCCGGCCACCAGCGTCGCTCTTCGTTCCAAACCTGATGGCCCTGCAGCCGCGCTTCTACTCAATCTCGTCGTCGCAGAAAAAGTTTCCGAACGAAGTTCACATAACGGTGGCAGTTGTAAAGTACCGGGCAAATGGTAAACGACCGAGTCTTTTGAACCAGAATAATATTTCGAAAGTTAAAATT
Protein: 1106 (aa)
MNQHISSMLEHFSSLRRKNSESAQTSSSDKQNATATAHREIDQKDVGADVETMSSKTKSILKDLMSENGATNILQNLNILKCNTPSSPASTNGTCKKQQTSNNNGHQRATNFLLPTTNETENVHNKKRNSIAAVTANGGCDLNVLREMSPSPQRMHRKSSHDIRLLRNHMQDGEKSTAVRPLKTKNILTKNETFDTLHYRGMDALGCSPQVCMGSVMFGNVMSTEVRKPTVIREHAIDFISQYYTSIRRFNSPAHQTRIQQIEKEIQETGAYQLSDSELIFGAKTAWRNSARCIGRIQWSKLQVFDCRHLLTPSQMFEALCNHIKYSTNKGNLRSAITIFPQRVANRPDFRIWNSQLISYAGYLNADGTITGDPLNVEITDVCIKLGWTSPRGEFDILPLVLSANGHDPEMFEFPPGLVLEVPLTHPQFTWFAEMNLKWYGVPAVSSMLFDCGGIVFPSVAFSGWYMSTEIACRDLCDSNRRNLIEPIAIKMGLDVRNPSSLWKDKALVEINIAVLHSYQTHNITIVDHHTASESFMKHYENECKVRGGCPADWVWIVPPMSASILQVFHQEMATYYLRPSFEYQEPAMKTHVWSKGRDSSKNKLPRRKFHFKQIARAVKFTSKLFGRALSRRIKATVLYATETGKSEQYAKQLVELLSHAFNAQLYDMAEYDISSIEHEALLLIVASTFGNGDPPENGEQFAQGLYAMKLHEAEEMEVNNTNIAASSKSFIKVNSRTERKKSQPKIDRLDSLRGSCSDSLFNETFGKLSNVRFAVFALGSSAYPNFCSFGKFVDNLLGELGGERLMKIVLGDDLCGQEHEFRKWACDVYKKSCEVFCLDLNDVCEMSLKGEALTKENTRFQAVRDANTPLNVLLSKYHNKKVHACRAKSKPINLHGMAEKNTILLEILIDDLVNYEPGDHVGVCAMNRKEYVDGILEKLTGVSDFDEPLQLQVLNEQHTANGLIKTWENHEKIPVCSLRTLLTRFLDITSPPSRQFLTFLLAHCEDFKDKERMRTLVNDSAAYEDWRHNKLPHLLEVFEEFTSCRPPASLFVPNLMALQPRFYSISSSQKKFPNEVHITVAVVKYRANGKRPSLLNQNNISKVKI
| Type | Start | End | Length |
| CDS |
176 |
198 |
23 |
| CDS |
295 |
702 |
408 |
| CDS |
765 |
915 |
151 |
| CDS |
1129 |
1546 |
418 |
| CDS |
1972 |
2121 |
150 |
| CDS |
2212 |
2384 |
173 |
| CDS |
2490 |
2634 |
145 |
| CDS |
3021 |
3105 |
85 |
| CDS |
3236 |
3324 |
89 |
| CDS |
3404 |
3621 |
218 |
| CDS |
3969 |
4018 |
50 |
| CDS |
4098 |
4175 |
78 |
| CDS |
4266 |
4312 |
47 |
| CDS |
4419 |
4478 |
60 |
| CDS |
4562 |
4641 |
80 |
| CDS |
4977 |
5051 |
75 |
| CDS |
5118 |
5184 |
67 |
| CDS |
5425 |
5516 |
92 |
| CDS |
5682 |
5844 |
163 |
| CDS |
7011 |
7147 |
137 |
| CDS |
11600 |
12208 |
609 |
| intron |
199 |
294 |
96 |
| intron |
703 |
764 |
62 |
| intron |
916 |
1128 |
213 |
| intron |
1547 |
1971 |
425 |
| intron |
2122 |
2211 |
90 |
| intron |
2385 |
2489 |
105 |
| intron |
2635 |
3020 |
386 |
| intron |
3106 |
3235 |
130 |
| intron |
3325 |
3403 |
79 |
| intron |
3622 |
3968 |
347 |
| intron |
4019 |
4097 |
79 |
| intron |
4176 |
4265 |
90 |
| intron |
4313 |
4418 |
106 |
| intron |
4479 |
4561 |
83 |
| intron |
4642 |
4976 |
335 |
| intron |
5052 |
5117 |
66 |
| intron |
5185 |
5424 |
240 |
| intron |
5517 |
5681 |
165 |
| intron |
5845 |
7010 |
1166 |
| intron |
7148 |
11599 |
4452 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
O61608 |
RecName: Full=Nitric oxide synthase; Short=NOS gb|AAC68577.1| nitric oxide synthase [Anopheles stephensi] |
0.0 |
| InterPro |
IPR026009 |
Nitric-oxide synthase |
|
| InterPro |
IPR017927 |
Ferredoxin reductase-type FAD-binding domain |
|
| InterPro |
IPR001094 |
Flavodoxin |
|
| InterPro |
IPR008254 |
Flavodoxin/nitric oxide synthase |
|
| InterPro |
IPR012144 |
Nitric-oxide synthase, metazoa |
|
| InterPro |
IPR004030 |
Nitric oxide synthase, oxygenase domain |
|
| InterPro |
IPR017938 |
Riboflavin synthase-like beta-barrel |
|
| InterPro |
IPR003097 |
FAD-binding, type 1 |
|
| InterPro |
IPR023173 |
NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 |
|
| Gene Ontology(BP) |
GO:0055114 |
oxidation-reduction process |
|
| Gene Ontology(BP) |
GO:0006809 |
nitric oxide biosynthetic process |
|
| Gene Ontology(MF) |
GO:0050661 |
NADP binding |
|
| Gene Ontology(MF) |
GO:0020037 |
heme binding |
|
| Gene Ontology(MF) |
GO:0005506 |
iron ion binding |
|
| Gene Ontology(MF) |
GO:0010181 |
FMN binding |
|
| Gene Ontology(MF) |
GO:0050660 |
flavin adenine dinucleotide binding |
|
| Gene Ontology(MF) |
GO:0005516 |
calmodulin binding |
|
| Gene Ontology(MF) |
GO:0004517 |
nitric-oxide synthase activity |
|
| Gene Ontology(MF) |
GO:0016491 |
oxidoreductase activity |
|
| Pfam |
PF00667.15 |
FAD binding domain |
6.1e-52 |
| Pfam |
PF00258.20 |
Flavodoxin |
9.6e-54 |
| Pfam |
PF07037.6 |
Putative transcription regulator (DUF1323) |
0.015 |
| Pfam |
PF02898.10 |
Nitric oxide synthase, oxygenase domain |
5.1e-200 |
| Pfam |
PF12724.2 |
Flavodoxin domain |
0.021 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000418245 |
| H. sapiens |
ENSP00000297494 |
| N. vitripennis |
NV18532-PA |
| H. sapiens |
ENSP00000420215 |
| H. melpomene |
HMEL005427-PA |
| H. sapiens |
ENSP00000320758 |
| H. sapiens |
ENSP00000417143 |
| C. quinquefasciatus |
CPIJ019871 |
| D. melanogaster |
FBgn0011676 |
| M. musculus |
ENSMUSG00000020826 |
| A. aegypti |
AAEL009745 |
| D. plexippus |
DPOGS202093PA |
| B. mori |
BGIBMGA002937-TA |
| H. sapiens |
ENSP00000327251 |
| D. plexippus |
DPOGS202094PA |
| H. sapiens |
ENSP00000339862 |
| B. mori |
BGIBMGA002938-TA |
| A. mellifera |
GB18010-PA |
| P. humanus |
PHUM176630-PA |
| S. invicta |
SI2.2.0_03517 |
| H. sapiens |
ENSP00000420551 |
| C. quinquefasciatus |
CPIJ000366 |
| A. gambiae |
AGAP008255 |
| H. sapiens |
ENSP00000337459 |
| T. castaneum |
TC012639 |
| M. musculus |
ENSMUSG00000028978 |
| P. vanderplanki |
Pv.10853 |
| H. melpomene |
HMEL005049-PA |
| M. musculus |
ENSMUSG00000029361 |
| A. gambiae |
AGAP008257 |