MidgeBase gene description page [Pn.13088]
Outline
| Gene ID | Pn.13088 |
| Type | Protein coding gene |
| Scaffold | PnScaf18385 |
| Start | 23437 |
| End | 24691 |
| Direction | + |
Sequence
Transcript: 1185 (bp)
ATGAAAAAGTTCCAAGTATCGGCTCCTGGGAAAATCATTCTCCATGGCGAACACTCTGTCGTTTACAACAAGGCAGCGATTGCCGGACCAATTGGATTAAAAACTTATTTTAGATTTGAGGAAACCACCAATGACTTCATTGTGCTTCAGTATAACCGCTTGAATCTCACTGCTCGCTTAACGCTTGTCAGCGCAAATCTCCTACTCACCGAGCTCGATTGCAACGAATCTCTTCAGCCAACGGAATTTTTGCAGAAGTTTCGTCAATCAAAGGACTTCATATTGAAGTACATCGAGCATAATTTCGACGAGAGAAAGCTCAATGACAAGGAAGAGATGGCTCTCGGTGCGACTCTTTACATACTCAATCGCATTCTGAAATGCGAAAAAGTGAAGATTATAAAGCAGGGATTTAATGTTACAATCGACTCTGACATGAGCATTGGGGCTGGTGTGGGCAGCTCTGCAAGCTACGGAGTCTGCCTTGCTGCCGGCTTCTATATTTACTCTCAGATCGTCGCCGGTAAGCTAAGTGATCAGCAGCTGAAAGAGTTTTCTTTCGAGAGGAACGACACCCTTCTCGAGCGCATTTCCAACTGGTCCTTCGACTCCGAGATCATCATGCATGAAAAGCCGTCAGGCATCGACAACACCATCTGCACTTACGGACAGTTGATAAAGTTCGTTCGAGGCCAAACGCCAGAGTCGATCAAAATGAATGGAAAAGTCGACATTTTGCTGGTCGATACGGGCGTTTCTAGAAGCACAAGCCACATCGTTGCAAAAGTGGCAAACTTCAAAAACAAGTACTCAAACGTCGCCAACTCAATTTTTGACGCAATGGGCTCTCTTGTCGATGACGTCATAAAAATTTTCGCAAGTCAAAAGTCGAGCGACGAAAAGTATCAGGAATTGAGCTTGCTCGTTGCTGTCAACAACAATCTCTTGCGTGCAATCGGCGTTTCGCATCCTCGTCTCGAGAAAGTCTTTCAAACTGCTGAGTCTTATGGATTTCAAGCTAAACTCACTGGTGCTGGTGGCGGTGGCTGCTCATTTGTCCTGCTGCCTTCAAACTACAAGGATCTGAAGGCGTACGAAAATCTTTGCGAAGATTTGAGAGCCAACAATTATCAAATCATGGCGACCGACATAGTCAACGGCAGCGGTGTTGAATTTAAATTTCTC
Protein: 395 (aa)
MKKFQVSAPGKIILHGEHSVVYNKAAIAGPIGLKTYFRFEETTNDFIVLQYNRLNLTARLTLVSANLLLTELDCNESLQPTEFLQKFRQSKDFILKYIEHNFDERKLNDKEEMALGATLYILNRILKCEKVKIIKQGFNVTIDSDMSIGAGVGSSASYGVCLAAGFYIYSQIVAGKLSDQQLKEFSFERNDTLLERISNWSFDSEIIMHEKPSGIDNTICTYGQLIKFVRGQTPESIKMNGKVDILLVDTGVSRSTSHIVAKVANFKNKYSNVANSIFDAMGSLVDDVIKIFASQKSSDEKYQELSLLVAVNNNLLRAIGVSHPRLEKVFQTAESYGFQAKLTGAGGGGCSFVLLPSNYKDLKAYENLCEDLRANNYQIMATDIVNGSGVEFKFL
| Type | Start | End | Length |
| CDS |
23437 |
24076 |
640 |
| CDS |
24144 |
24688 |
545 |
| intron |
24077 |
24143 |
67 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001657825 |
mevalonate kinase [Aedes aegypti] gb|EAT41980.1| mevalonate kinase [Aedes aegypti] |
1e-109 |
| InterPro |
IPR006205 |
Mevalonate kinase |
|
| InterPro |
IPR006206 |
Mevalonate/galactokinase |
|
| InterPro |
IPR020568 |
Ribosomal protein S5 domain 2-type fold |
|
| InterPro |
IPR006204 |
GHMP kinase N-terminal domain |
|
| InterPro |
IPR014721 |
Ribosomal protein S5 domain 2-type fold, subgroup |
|
| InterPro |
IPR013750 |
GHMP kinase, C-terminal domain |
|
| Gene Ontology(BP) |
GO:0008299 |
isoprenoid biosynthetic process |
|
| Gene Ontology(BP) |
GO:0008152 |
metabolic process |
|
| Gene Ontology(CC) |
GO:0005737 |
cytoplasm |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0016301 |
kinase activity |
|
| Gene Ontology(MF) |
GO:0016773 |
phosphotransferase activity, alcohol group as acceptor |
|
| Gene Ontology(MF) |
GO:0004496 |
mevalonate kinase activity |
|
| Pfam |
PF00288.21 |
GHMP kinases N terminal domain |
3.1e-13 |
| Pfam |
PF08544.8 |
GHMP kinases C terminal |
2.2e-08 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000443551 |
| B. mori |
BGIBMGA013075-TA |
| A. aegypti |
AAEL006435 |
| P. vanderplanki |
Pv.10061 |
| M. musculus |
ENSMUSG00000041939 |
| P. humanus |
PHUM448520-PA |
| D. melanogaster |
FBgn0061359 |
| H. sapiens |
ENSP00000228510 |
| T. castaneum |
TC015408 |
| A. gambiae |
AGAP008947 |
| A. mellifera |
GB14701-PA |
| C. quinquefasciatus |
CPIJ004201 |
| N. vitripennis |
NV10452-PA |
| D. plexippus |
DPOGS207113PA |
| H. sapiens |
ENSP00000376487 |