MidgeBase gene description page [Pn.12528]

Outline

Link to gbrowse

Gene ID Pn.12528
Type Protein coding gene
Scaffold PnScaf16823
Start 2275
End 4375
Direction +

Sequence

Transcript: 1803 (bp)

 ATGCCCGTAGTCAACAGCAGCAGCGGTGGCAACAATAATGACTCGTCGACGCTTGCAAATGACGTTAAAGTGAAAATCGCCTACAATGGCGAGGTGCTCATCTTTTACATCGACGAGAACATCACGTACGAGGAGCTGTGCAAGGAAATCCGCGGCATTTGTCGCTTTGCGCCCGACCAAGTCTTCACGATGAAGTGGATCGACGAGGAGAACGACCCGTGCACGATAAGCTGTCAGATGGAGCTGAACGAGGCGATTCGTTTGTACGAGGTGAATCGCGACTCGGAGCTCTTCATACACGTCTTTCCTAATGCGCCCGCCGCGCCCGGGCTCTCGTGCATCGGCGAGGACAAGAGCATCTACAGACGCGGCGCAAGACGGTGGCGCAAGCTCTACCGCATCAACGGACACATCTTTCAGGCTAAGCGCTTCAATCGGCGCGCGTTCTGCGCCTTCTGTCACGATCGCATTTGGGGCCTCGGACGGCAGGGCTTCAAGTGCATCCAGTGCAAGCTACTGGTACATAAGAAGTGCCACAAGCTACTTCAGAAGCCCTGCAACGAGCAGATGGAACCGCTCGACCGAATCGACCGGAATGGCGAGAGTGAGCCGAAACTGGCACCCGGAGCCGAAGTTTCATCGACAACAATAGTCGAGTACCAGCCCGGCGAGGGCGACCAGGTGGCGGTCGAGTCACCGGCACAGCCGCACGCGGACGAGCCGCTCGAGCCGGGCTCGCAGCGGCAGTACTCGCTGTTGGACTTCGAACTGATTCGCGTGATTGGCCGCGGCAGCTACGCAAAGGTGCTAATGGTGGAGCTCAAGCGCACCAAACGAATTTACGCGATGAAGGTCATTAAGAAGGCGCTGGTGACAGACGACGAGGACATCGATTGGGTGCAAACCGAGAAGCACGTGTTCGAGACGGCCTCTAATCATCCGTTCCTCGTGGGCCTGCACTCGTGCTTCCAAACACCCTCGCGGCTCTTCTTCGTCATCGAGTTCGTGCGAGGTGGCGACCTGATGTTCCACATGCAGCGGCAGCGACGGCTGCCTGAGGAGCATGCGCGATTTTATGCGGCCGAGATCAGTTTAGCACTCAACTTTCTCCATGAGAAGGGCATCATTTATCGTGACCTCAAGCTCGACAACGTCCTCCTCGATCACGAGGGCCACATCAAGCTCACCGACTACGGCATGTGCAAAGAGGGCATCAAGACGGGCGACACGACCGCTACCTTCTGCGGAACGCCCAATTATATCGCTCCTGAAATTCTGCGTGGCGAGGATTATGGATTTAGCGTCGACTGGTGGGCGCTCGGCGTGCTTCTCTACGAAATGCTCGCAGGACGATCGCCCTTCGACATCGCCGGCGCCTCGGAAAATCCCGATCAAAACACGGAGGACTATCTCTTCCAAGTGATTCTCGAAAAGACAATTCGCATTCCGCGGTCGCTGAGCGTAAAGGCAGCTTCCGTTCTCAAGGGTTTCCTCAACAAGAACCCGGCGGACCGGTTGGGTTGTAGTCGAGAGGGCGCCTTCATGGACATCGTGAATCATCCGTTCTTCAAGCAAATCGATTGGAACATGCTCGAACAGAAACAGGTTACGCCGCCGTTCAAGCCGCGATTAGATAATGAGAGAGACATAAGAGATGACCTAGCCAATTTCCCTCCTGAATTCACCGATGAGCCGGTCCATTTGACACCTGACGATGAAAAAATCATCGAGAAAATCGATCAATCGGAGTTCGAGGGATTCGAATATGTTAATCCCCTGCTGATGTCGCTCGAAGACTGCGTT 

Protein: 601 (aa)

 MPVVNSSSGGNNNDSSTLANDVKVKIAYNGEVLIFYIDENITYEELCKEIRGICRFAPDQVFTMKWIDEENDPCTISCQMELNEAIRLYEVNRDSELFIHVFPNAPAAPGLSCIGEDKSIYRRGARRWRKLYRINGHIFQAKRFNRRAFCAFCHDRIWGLGRQGFKCIQCKLLVHKKCHKLLQKPCNEQMEPLDRIDRNGESEPKLAPGAEVSSTTIVEYQPGEGDQVAVESPAQPHADEPLEPGSQRQYSLLDFELIRVIGRGSYAKVLMVELKRTKRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMFHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIKTGDTTATFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCSREGAFMDIVNHPFFKQIDWNMLEQKQVTPPFKPRLDNERDIRDDLANFPPEFTDEPVHLTPDDEKIIEKIDQSEFEGFEYVNPLLMSLEDCV 
Type Start End Length
CDS 2275 3538 1264
CDS 3769 4156 388
CDS 4222 4372 151
intron 3539 3768 230
intron 4157 4221 65

Auto annotation result

Program/Analysis Accession Description Score/Expectation
BLASTP/NCBI-nr XP_001361462 GA10200 [Drosophila pseudoobscura pseudoobscura] gb|EAL26040.1| GA10200 [Drosophila pseudoobscura pseudoobscura] 0.0
InterPro IPR000270 Phox/Bem1p
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR012233 Protein kinase C, zeta/iota
InterPro IPR002290 Serine/threonine- / dual-specificity protein kinase, catalytic domain
InterPro IPR020454 Diacylglycerol/phorbol-ester binding
InterPro IPR011009 Protein kinase-like domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
InterPro IPR000961 AGC-kinase, C-terminal
InterPro IPR017892 Protein kinase, C-terminal
InterPro IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR020635 Tyrosine-protein kinase, catalytic domain
Gene Ontology(BP) GO:0006468 protein phosphorylation
Gene Ontology(BP) GO:0035556 intracellular signal transduction
Gene Ontology(MF) GO:0004713 protein tyrosine kinase activity
Gene Ontology(MF) GO:0004674 protein serine/threonine kinase activity
Gene Ontology(MF) GO:0005515 protein binding
Gene Ontology(MF) GO:0005524 ATP binding
Gene Ontology(MF) GO:0004672 protein kinase activity
Gene Ontology(MF) GO:0008270 zinc ion binding
Gene Ontology(MF) GO:0016772 transferase activity, transferring phosphorus-containing groups
Pfam PF07649.7 C1-like domain 0.2
Pfam PF00628.24 PHD-finger 0.5
Pfam PF00564.19 PB1 domain 6e-14
Pfam PF01636.18 Phosphotransferase enzyme family 0.068
Pfam PF07714.12 Protein tyrosine kinase 5.7e-33
Pfam PF00069.20 Protein kinase domain 1.2e-63
Pfam PF06293.9 Lipopolysaccharide kinase (Kdo/WaaP) family 0.095
Pfam PF00130.17 Phorbol esters/diacylglycerol binding domain (C1 domain) 3.3e-12
Pfam PF00433.19 Protein kinase C terminal domain 2.3e-10
Pfam PF14446.1 Prokaryotic RING finger family 1 0.19
Pfam PF13901.1 Domain of unknown function (DUF4206) 0.046

Expression level (RPKM)

Paralog/Ortholog genes

Paralogous genes

Gene ID
Pn.16338

Orthologous genes

Species Gene ID
A. aegypti AAEL002885
S. invicta SI2.2.0_06688
T. castaneum TC005980
P. humanus PHUM529700-PA
P. vanderplanki Pv.02261
H. sapiens ENSP00000424398
H. sapiens ENSP00000383711
H. sapiens ENSP00000295797
P. vanderplanki Pv.02525
H. sapiens ENSP00000426412
A. mellifera GB19525-PA
D. plexippus DPOGS209483PA
C. quinquefasciatus CPIJ013835
H. sapiens ENSP00000383712
D. melanogaster FBgn0261854
H. sapiens ENSP00000367830
N. vitripennis NV14702-PA