MidgeBase gene description page [Pn.12288]
Outline
| Gene ID | Pn.12288 |
| Type | Protein coding gene |
| Scaffold | PnScaf16028 |
| Start | 12174 |
| End | 15014 |
| Direction | - |
Sequence
Transcript: 1650 (bp)
ATGGCAGAGAGCAAAGAAAGTGCAGTGAATGGTCATCACAAGGCGACCACTTGTTTGACTCATCTCAAGTATAAATCGCTCGAAATGCCCGAAACCCTCCAGACCGACTTTGTGTATCCGGACATGCCGTCGAAGTGTACGTGGGTGCGCGAAAAGTCCGATCAGCCCGCGACTCCGCACACCGTTCGACCCTTTCACGAGCGTCCCAAGACAATTCCGCACATTCTCGATGCAATCGGGATGACGCCGCTCGTGAGACTCAACAAGATCCCGCAGTCGATGGGCGTCAAGTGTCAAGTTTTTGCGAAATGCGAGTTCCTTAACCCAGGCGGTTCAGTCAAGGACAGAATCGGCTACCGGATGGTGCTCGATGCCGAAGAAAAAGGCCTCCTCAAGCCGGGCTACACCGTCATCGAGCCGACTTCGGGCAACACGGGAATCGGCCTGGCCATGGCGAGCGCCGTGCGCGGCTATCGCTGCATCATCGTCCTGCCTGAGAAGAACTCCGACGAGAAGGTGAACACGCTGAAGGCGCTCGGCGCCGAAATCATTCGCACGCGCACCGAAGCGAAATTCGATGAGCCCGACTCGCTCGTGGCCGTCGCGCAGCGTCTGCAGAAGGAGATCCCGAACTCGGTCATCCTCAACCAGTACACGAACGCCGGCAACCCGCTCGCCCACTACGACGGCACCGGCAGCGAAATTCTCTACCAACTCAACGGCAAGGTCGACATGGTGGTGCTCGGCGCTGGCACCGGCGGCACTGTCACCGGAGTCGGCCGCCGCATCAAGGAGGAGTGCCCGAACTGCAAAATTGTCGCCGTCGACCCCGAGGGCTCGATCCTCGCGCGACCAGAATCTCTCAACGAGTCGGACGTCGTGGTCTACGATGTCGAGGGCATCGGCTACGACTTCATTCCCACCGTCCTCGACCGCGACGTCGTCGACAAGTGGATGAAGACGAACGACCGGCTGGCGTTCCCGATGGCGAAGCGGCTGATTCGCGAGGAGGGCTTTTTGTGCGGCGGGTCGAGTGGCGCCGCGATGGCGGCTGCCATGGAAGCGGCGCGCGATCTGAGTGAGGACGACGTGTGCGTGGTCATTTGCCCCGACAACGTGCGCAACTACATGTCGAAGTTCCTCGTCGACAACTGGATGGAGGCGCGCGGTCACAAGGACTCGGTCAACGTCCACTGCCACACGTGGTGGAACGTCAAGATCTCCAACCTCATCGCCAACGACTCGCCCATGACCGTCACCGAGACGGTTGCGTGTCGCGAGGTGCTCGAGAAGTTGCGCGCGAGTCATCTTCAGCAGGTGGCCGTCACTGACTTACATGGCGGCATCAAGGGAATGGCGACCGTGAGCCACATCATGGGCAAGATTTTGGACCGCTCGCTCAACTTCGACGACCCGATTTCGCGCGGGCTCTTCACGAAGTTCATCAAGGTGCGCATGGACACGACCGTCGGACGACTGTCGCGCATCCTCGAGACGGAGCCGTACGTCGTCGTCGTTCAGAAGCGCGAAATTCACGACCGCACCGAGACGAAAAACATCGAGCACGTCATCGCTGTGCTCACGCAAAAAGATCTTCTCAACTACATCTCGACCCACACTGACTGCGGGCAGAACGGACAGAACGGTCAC
Protein: 550 (aa)
MAESKESAVNGHHKATTCLTHLKYKSLEMPETLQTDFVYPDMPSKCTWVREKSDQPATPHTVRPFHERPKTIPHILDAIGMTPLVRLNKIPQSMGVKCQVFAKCEFLNPGGSVKDRIGYRMVLDAEEKGLLKPGYTVIEPTSGNTGIGLAMASAVRGYRCIIVLPEKNSDEKVNTLKALGAEIIRTRTEAKFDEPDSLVAVAQRLQKEIPNSVILNQYTNAGNPLAHYDGTGSEILYQLNGKVDMVVLGAGTGGTVTGVGRRIKEECPNCKIVAVDPEGSILARPESLNESDVVVYDVEGIGYDFIPTVLDRDVVDKWMKTNDRLAFPMAKRLIREEGFLCGGSSGAAMAAAMEAARDLSEDDVCVVICPDNVRNYMSKFLVDNWMEARGHKDSVNVHCHTWWNVKISNLIANDSPMTVTETVACREVLEKLRASHLQQVAVTDLHGGIKGMATVSHIMGKILDRSLNFDDPISRGLFTKFIKVRMDTTVGRLSRILETEPYVVVVQKREIHDRTETKNIEHVIAVLTQKDLLNYISTHTDCGQNGQNGH
| Type | Start | End | Length |
| CDS |
12177 |
12292 |
116 |
| CDS |
12382 |
13614 |
1233 |
| CDS |
13693 |
13799 |
107 |
| CDS |
14821 |
15014 |
194 |
| intron |
12293 |
12381 |
89 |
| intron |
13615 |
13692 |
78 |
| intron |
13800 |
14820 |
1021 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001659242 |
cysteine synthase [Aedes aegypti] gb|EAT39750.1| cysteine synthase [Aedes aegypti] |
1e-170 |
| InterPro |
IPR001216 |
Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site |
|
| InterPro |
IPR005857 |
Cystathionine beta-synthase |
|
| InterPro |
IPR001926 |
Pyridoxal phosphate-dependent enzyme, beta subunit |
|
| InterPro |
IPR000644 |
Cystathionine beta-synthase, core |
|
| Gene Ontology(BP) |
GO:0019343 |
cysteine biosynthetic process via cystathionine |
|
| Gene Ontology(BP) |
GO:0008152 |
metabolic process |
|
| Gene Ontology(BP) |
GO:0006535 |
cysteine biosynthetic process from serine |
|
| Gene Ontology(CC) |
GO:0005737 |
cytoplasm |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0004122 |
cystathionine beta-synthase activity |
|
| Gene Ontology(MF) |
GO:0003824 |
catalytic activity |
|
| Gene Ontology(MF) |
GO:0030170 |
pyridoxal phosphate binding |
|
| Pfam |
PF00571.23 |
CBS domain |
6e-08 |
| Pfam |
PF00291.20 |
Pyridoxal-phosphate dependent enzyme |
7.5e-61 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
| Gene ID |
| Pn.03111 |
| Pn.02977 |
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000439332 |
| D. melanogaster |
FBgn0031148 |
| A. aegypti |
AAEL008467 |
| H. sapiens |
ENSP00000381234 |
| P. humanus |
PHUM607830-PA |
| H. sapiens |
ENSP00000352643 |
| D. plexippus |
DPOGS202279PA |
| C. quinquefasciatus |
CPIJ012752 |
| A. gambiae |
AGAP000162 |
| B. mori |
BGIBMGA005174-TA |
| D. plexippus |
DPOGS202278PA |
| H. sapiens |
ENSP00000344460 |
| B. mori |
BGIBMGA004935-TA |
| P. vanderplanki |
Pv.10384 |
| H. melpomene |
HMEL014964-PB |
| A. mellifera |
GB12529-PA |
| H. sapiens |
ENSP00000381225 |
| H. melpomene |
HMEL014964-PA |
| H. melpomene |
HMEL004722-PA |
| H. sapiens |
ENSP00000381231 |
| S. invicta |
SI2.2.0_06230 |
| P. humanus |
PHUM459670-PA |
| B. mori |
BGIBMGA000065-TA |
| C. quinquefasciatus |
CPIJ012753 |
| A. aegypti |
AAEL008468 |
| P. vanderplanki |
Pv.10385 |
| T. castaneum |
TC009131 |
| N. vitripennis |
NV17942-PA |