MidgeBase gene description page [Pn.12237]
Outline
| Gene ID | Pn.12237 |
| Type | Protein coding gene |
| Scaffold | PnScaf15869 |
| Start | 138549 |
| End | 142287 |
| Direction | + |
Sequence
Transcript: 3603 (bp)
ATGACGGAGGAAAAGGATTTTCTGGAGGATTCGGACAAACGTCTCGAAAATTATGTCACGAACCCGGACTTGCCAAAATTGCACGACCCAAAACCATCTTGTCCAACACATCAATCGTCATCGCTAGAAAAACTCCTTCACATTCCACCGTCGGCACAGAACACTCAGATTATAGCAAAACGCAATCAAGAAACGGGCAAAATTGAAGGATTTGTCGAAGTGGAAATAGAAAATGCCGGGTCAGATTCTAAAAATTCGTTTTCGATGAATCGAGCTCCAAATCAGCAGCAACAGGCGACTAGAGGATCTGCTTCGAATTTTCCTTTTTGGCCGGGGGGATTCGATAAACCGAACGAGGACATTGAAGCCTTGAAAGTCGATGACAATCACAACTTCTACGAAAATCTTCTCACTGTCGCGCCGGGATTCTCTACTGGATTGGACTTCAGTCATCTGGTGAATACCGACAAAAAGAAGGAGAAAGAGGCTGAAATCTCCACGGTTAATCTGCTTGCAGCTATCGAGAACCAAGACGGTGACATCTTCAGCATTTCTAGTGACAACAAAAATGAAGTGAAAGAGTCGGCAGTTGAAACTGAAAAGCGGCCACTCTTGAACATTTCCTTCGATGATTCATTGCTGGAAATTAAAAAGGATGATACACAGAGTGTCATTCAAATTACCGACTCGCAAAAGAAGCAGGATCAGAGCAGAGAGTGGGCCGAACTCATCGACATTACTCAACCGGTGAAGAATTTTTACGACAGAGTCGCCGACATGGCGCATCAGTATCCCTTCGAATTGGACAACTTCCAGAAGCAGGCGATTCTCAAGCTCGAGAGTCACGATCATGTTTTTGTGGCGGCACACACTTCGGCTGGAAAGACCGTCGTCGCCGAGTACTGCATTGCTCTGTCGATGAAGCACATGACCAAGTCAATCTACACGTCTCCCATCAAAGCACTCTCGAATCAAAAGTATCGAGACTTCAAGCAAACTTTCGGTGATGTCGGACTCATAACTGGCGACATTCAGATAAACCAGACAGCCAATTGCCTCATCATGACCACTGAAATTCTCCGCTCCATGCTCTACTGTGGCAGCGACGTAACTCGAGACTTGGAGTATGTGATTTTCGACGAGGTGCATTACATCGCAGACGCGGAGAGAGGACATGTTTGGGAGGAAGTCTTGATTTTGCTTCCCGATCACGTGTCGATTGTCATGCTCTCAGCAACCGTTCCCAACTATTTGGAATTTGCCAATTGGGTTGGAAGAACCAAGCGAAAGAAGGTGTACGTCATCAGCACTCTCAAGCGACCCGTTCCGCTGCAGCACTTTTTGTACACGGGCAACGGCGGAAAGTCGCGAGACGACATTTTCCTGCTCGTCGACGAAAACGGCAAATATCTCACAGACGGTTATGCGAAAGCGAAGGCCACAAAGACCGCTCGCCAAAAAGAGTATCAGAAGAATTTCGGCGCCAAAGTCTCCACCTTCCTGAATCCCAAGCAGGAGAAGACGATGTGGGAGGGGTTGATTGGGCATCTGAAGAAGAACGACCGGCTGCCGGTTGTCGCATTCACTCTATCGCGAAATCGCTGCGATGCCAATGCGGAGGCCTTAAAATCGTGCGACTTGACAACTGCCCGCGAGAAATTCAAAATCTCTTCCTTCTTCAAGATGTGCATTCAGAAGCTCAAGACCGAGGACAGAGAACTGCCGCAGGTGCTGACGATTCAGGATTGCCTCGAGCGCGGCATCGGAGTTCATCACTCGGGCATTTTGCCGATTCTCAAAGAGATTGTCGAGATGTGCTTTCAATGCGGGCTTGTCAAACTGCTCTTTGCGACCGAAACGTTTGCGATGGGAGTCAACATGCCGGCCAGAACCGTCATTTTTGATGCAATCACGAAATTCGACGGAAAAAATTCGCGCAATCTAGAATCAGCGGAGTACACGCAAATGGCAGGCAGAGCAGGCAGGCGAGGTCTCGATTCGACCGGCACCGTCATAATTCTGTGCAAAACCGACCTTCCACATCCCGAGGTGCTGAAGAAAATGATTTTGGGGAAGCCGATTCAGTTGGAGTCGAAATTCAAGCTGACGTACGCGATGATTCTCTCGCTGCTGCGCGTGGAGCGAGTCTCAGTCGAGGACATGATGCAGCACAGCTTCTGGGAGTTTAAGAAGCAACTCAAGGTGCCGGAAAACAAGAAGCAGCTGGAACTTGCTGAAAAGAAGTTGTCGGAATTGACTGAGATTTCCGAACATTTGGCTCCAATGTCCAACTTTTACATCGCATGCAGGGAGTTTCTGGCGGTTTTCGATGAGGCGATGCCCGAATTCATAGCGCAACCGAAAGTCTTTAACGAGATGAAGAGCGGTCGTGTGGTGATTGTGAGCACAGAAAATCACTACAACAAGTATGGAATTCTGCTGAAAGCAGACTTGGCGTCGCTGACTTTCAAAGTCTTGGTGCTGAATAGCGAGGAAAATTTGGACGAAATCTACCAAAAGAAGGGCTCGCTCTGGCACCGGATCATTGCTCTCTCGAGAAATTTCGACAACTCGAGCAACGATAGTGGCGAGCACACAATACTCACTTTAAAGGCCACGGACATCTTCGAGATAACGCGCACACTTTTAAAGTGCGACGGCGAGAAAATCATTCTTAATTGGGAGCAGCGGCAGATTCCGCGCTTCAAAGACAACCCGCCCGGTCCAAGTGTCGCGCAGGCTGTTCTCGACTTGAGCGCACTCATCAAGTCCAATCCGAAGCTTGAGTGCATGCCGCTGACGAGTCAGAACATTGAGCTCTTCGAGAAGCTGCAAAAACTCGCGGAGCTGCGCGAAAATATTGAACTTTATCGACCGTACACGAATGTGCCGAATTTCCTTGAAAAGTTCTCGCAAGTCTTCGACAGAAAAGTTCTCGAGGACAGAAAGGAAAGTTTGATATTCCAGCTGTCGAATAAGAACCTCTCGCTTTATCCCGACTACTGCAACAAGTTGCTCGTGCTGCAAGAGCTCAAGTACATCGATGAACTCAATCAGGTTGCGCTGAAGGGTCGTGTAGCTTGTGAAATGGGACAGAATGAGCTCATAATTACGGAGCTCGTGTTGCGCAACATCCTCACAAATCTCGAGCCTGCGGAAATCGCCGCTCTCCTCTCCAGCTTGGTGTTTCAAGCCAAAACGGACGTTGAGCCGAGCGTGTCTGACAAGATGAAGGCGCTGATGCAGAAAGTCGCCGAAGTCGATGAGTCCATTCGTGACGTCGAAGTTAAGTATAAAGTGGGAAGCGCGGACGACAGCGTCGAGAGAGATCGTCTCAATTTTGGCTTGGTCGAAGTCGTGTACGAATGGGCGAGGAACAAGCCGTTTGCCGAAATCATTCAACTGACTGACATAAAGGAGGGCGTCATTGTGAGATGCATTCAGCAGTTGCATGAGACACTGAGCGATGTGAAGGATGCGGCGAGAATCATTGGTGATCCTGTTTTGCATTCGAAGATGGAAGATGCTTCGAACGCCATCAAGCGCGACATCGTCTTTGCTGCCTCGCTTTACACGCTCAACGACACTCTCAGTCTCACTTCG
Protein: 1201 (aa)
MTEEKDFLEDSDKRLENYVTNPDLPKLHDPKPSCPTHQSSSLEKLLHIPPSAQNTQIIAKRNQETGKIEGFVEVEIENAGSDSKNSFSMNRAPNQQQQATRGSASNFPFWPGGFDKPNEDIEALKVDDNHNFYENLLTVAPGFSTGLDFSHLVNTDKKKEKEAEISTVNLLAAIENQDGDIFSISSDNKNEVKESAVETEKRPLLNISFDDSLLEIKKDDTQSVIQITDSQKKQDQSREWAELIDITQPVKNFYDRVADMAHQYPFELDNFQKQAILKLESHDHVFVAAHTSAGKTVVAEYCIALSMKHMTKSIYTSPIKALSNQKYRDFKQTFGDVGLITGDIQINQTANCLIMTTEILRSMLYCGSDVTRDLEYVIFDEVHYIADAERGHVWEEVLILLPDHVSIVMLSATVPNYLEFANWVGRTKRKKVYVISTLKRPVPLQHFLYTGNGGKSRDDIFLLVDENGKYLTDGYAKAKATKTARQKEYQKNFGAKVSTFLNPKQEKTMWEGLIGHLKKNDRLPVVAFTLSRNRCDANAEALKSCDLTTAREKFKISSFFKMCIQKLKTEDRELPQVLTIQDCLERGIGVHHSGILPILKEIVEMCFQCGLVKLLFATETFAMGVNMPARTVIFDAITKFDGKNSRNLESAEYTQMAGRAGRRGLDSTGTVIILCKTDLPHPEVLKKMILGKPIQLESKFKLTYAMILSLLRVERVSVEDMMQHSFWEFKKQLKVPENKKQLELAEKKLSELTEISEHLAPMSNFYIACREFLAVFDEAMPEFIAQPKVFNEMKSGRVVIVSTENHYNKYGILLKADLASLTFKVLVLNSEENLDEIYQKKGSLWHRIIALSRNFDNSSNDSGEHTILTLKATDIFEITRTLLKCDGEKIILNWEQRQIPRFKDNPPGPSVAQAVLDLSALIKSNPKLECMPLTSQNIELFEKLQKLAELRENIELYRPYTNVPNFLEKFSQVFDRKVLEDRKESLIFQLSNKNLSLYPDYCNKLLVLQELKYIDELNQVALKGRVACEMGQNELIITELVLRNILTNLEPAEIAALLSSLVFQAKTDVEPSVSDKMKALMQKVAEVDESIRDVEVKYKVGSADDSVERDRLNFGLVEVVYEWARNKPFAEIIQLTDIKEGVIVRCIQQLHETLSDVKDAARIIGDPVLHSKMEDASNAIKRDIVFAASLYTLNDTLSLTS
| Type | Start | End | Length |
| CDS |
138549 |
138557 |
9 |
| CDS |
138629 |
142000 |
3372 |
| CDS |
142063 |
142284 |
222 |
| intron |
138558 |
138628 |
71 |
| intron |
142001 |
142062 |
62 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001845019 |
antiviral helicase SKI2 [Culex quinquefasciatus] gb|EDS39035.1| antiviral helicase SKI2 [Culex quinquefasciatus] |
0.0 |
| InterPro |
IPR011545 |
DNA/RNA helicase, DEAD/DEAH box type, N-terminal |
|
| InterPro |
IPR012961 |
DSH, C-terminal |
|
| InterPro |
IPR014001 |
Helicase, superfamily 1/2, ATP-binding domain |
|
| InterPro |
IPR025696 |
rRNA-processing arch domain |
|
| InterPro |
IPR016438 |
RNA helicase, ATP-dependent, SK12/DOB1 |
|
| InterPro |
IPR001650 |
Helicase, C-terminal |
|
| Gene Ontology(MF) |
GO:0016817 |
hydrolase activity, acting on acid anhydrides |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0016818 |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
|
| Gene Ontology(MF) |
GO:0004386 |
helicase activity |
|
| Gene Ontology(MF) |
GO:0008026 |
ATP-dependent helicase activity |
|
| Gene Ontology(MF) |
GO:0003676 |
nucleic acid binding |
|
| Pfam |
PF00270.24 |
DEAD/DEAH box helicase |
3.2e-20 |
| Pfam |
PF13234.1 |
rRNA-processing arch domain |
1.2e-07 |
| Pfam |
PF08148.7 |
DSHCT (NUC185) domain |
2.6e-55 |
| Pfam |
PF00271.26 |
Helicase conserved C-terminal domain |
9.8e-06 |
| Pfam |
PF04851.10 |
Type III restriction enzyme, res subunit |
0.00078 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| A. aegypti |
AAEL009067 |
| A. gambiae |
AGAP003182 |
| H. sapiens |
ENSP00000448686 |
| A. mellifera |
GB14198-PA |
| T. castaneum |
TC010559 |
| H. sapiens |
ENSP00000447652 |
| S. invicta |
SI2.2.0_13431 |
| H. sapiens |
ENSP00000448582 |
| P. humanus |
PHUM420000-PA |
| H. sapiens |
ENSP00000448237 |
| T. castaneum |
TC009717 |
| P. vanderplanki |
Pv.02634 |
| C. quinquefasciatus |
CPIJ003293 |
| A. mellifera |
GB13548-PA |
| H. sapiens |
ENSP00000448401 |
| H. sapiens |
ENSP00000448135 |
| H. melpomene |
HMEL014101-PA |
| H. sapiens |
ENSP00000230640 |
| H. sapiens |
ENSP00000372827 |
| H. sapiens |
ENSP00000446557 |
| H. sapiens |
ENSP00000412310 |
| H. sapiens |
ENSP00000448717 |
| A. aegypti |
AAEL013825 |
| A. gambiae |
AGAP009600 |
| S. invicta |
SI2.2.0_80448 |
| H. sapiens |
ENSP00000449802 |
| D. melanogaster |
FBgn0001986 |
| H. sapiens |
ENSP00000442583 |
| M. musculus |
ENSMUSG00000016018 |
| B. mori |
BGIBMGA003539-TA |
| H. sapiens |
ENSP00000448265 |
| N. vitripennis |
NV17547-PA |
| P. humanus |
PHUM218140-PA |
| H. sapiens |
ENSP00000448094 |
| P. vanderplanki |
Pv.03556 |
| H. melpomene |
HMEL003445-PA |
| B. mori |
BGIBMGA005168-TA |
| N. vitripennis |
NV18659-PA |
| D. plexippus |
DPOGS215771PA |
| H. sapiens |
ENSP00000449929 |
| D. plexippus |
DPOGS211231PA |
| H. sapiens |
ENSP00000447626 |
| D. melanogaster |
FBgn0039117 |
| H. sapiens |
ENSP00000400626 |
| C. quinquefasciatus |
CPIJ801392 |
| H. sapiens |
ENSP00000364543 |
| H. sapiens |
ENSP00000394400 |
| H. sapiens |
ENSP00000447619 |
| H. sapiens |
ENSP00000448695 |
| H. sapiens |
ENSP00000442645 |
| H. sapiens |
ENSP00000399530 |