MidgeBase gene description page [Pn.12184]
Outline
| Gene ID | Pn.12184 |
| Type | Protein coding gene |
| Scaffold | PnScaf15721 |
| Start | 16829 |
| End | 18226 |
| Direction | - |
Sequence
Transcript: 996 (bp)
ATGCCGGCAATCGAGGCAGAGTTATTCATTAAAGATAGCGCGAACGCCGCAGTTAAGCCGCGCAATAAAGTCACAGTTATCGGCGCCGGTCAAGTCGGAACCGCTACTGCCTTCTCTATTCTGCTCCAGAATGTCTCCAGCGACATCGCCCTCGTCGATATCGACGAGAACAAGTTGAAGGGCGAGCTCATGGACTTCTTGCACGGCTCGAGCTTCTTCGATGCCAACATCACGGCCAGTTCCGATTTGAAGGTGTCGGCGGGTTCGAGTCTCATCATAATCGCGGCAGGCGTTCGCCAGAAGGAGGGCGAGTCGCGCCTCGCACTCCTCGAGCGCAACGTCGAGACAATCAAGAGCATCGTGCCGAAGGTGCTCGAGTTCAGCCCGGACGCAACCCTTCTCATCATGACCAACCCATGCGACGTCATGAGCTATGTTGCGTGGAAGCTCAGTGGCTTGCCCAAGAACCGCGTCTTCGGCTCGGGCAACAATCTCGACTCGTCGCGCTTCCGCTTCGCACTCTCGCAGAAACTCGGCGTCGGCGCGACTAGCACGCATGGCTGGGTCATCGGCGAGCACGGCGACTCCTCGGTGCCGGTTTGGTCGGAGGTCAACGTAGCCGGCGTTCCGCTGCAAAAGTACTGCCCGAGCGCGGGTCAGGAGGGCGATCCCGATAACTGGAACCAGTGTCACAAGGACGTTGTGAGCGCGGCCTACGAGGTCATCAGCCTGAAGGGCTACACGTCGTGGGCCGGCGCCCTCAGCACGGCCGACATCGCCTCGGCCTTCCTGAACAACGACAACTCGGTGAAAGCCGTATCGACACTCGTGAAGGGCGTGCACGGCATTGATAAAGAAGTCTTCTTATCGCTTCCTTGCGTAATCAATGCTAATGGCGTTTCGTCGATCGTCAAGCAGACGCTCAGCGCGGACGAAGTGAAGAAATTGCAGGCGTCCGCGAATATCATTGATGAAGTTCAAAAGAAAATTTCCTTC
Protein: 332 (aa)
MPAIEAELFIKDSANAAVKPRNKVTVIGAGQVGTATAFSILLQNVSSDIALVDIDENKLKGELMDFLHGSSFFDANITASSDLKVSAGSSLIIIAAGVRQKEGESRLALLERNVETIKSIVPKVLEFSPDATLLIMTNPCDVMSYVAWKLSGLPKNRVFGSGNNLDSSRFRFALSQKLGVGATSTHGWVIGEHGDSSVPVWSEVNVAGVPLQKYCPSAGQEGDPDNWNQCHKDVVSAAYEVISLKGYTSWAGALSTADIASAFLNNDNSVKAVSTLVKGVHGIDKEVFLSLPCVINANGVSSIVKQTLSADEVKKLQASANIIDEVQKKISF
| Type | Start | End | Length |
| CDS |
16832 |
17575 |
744 |
| CDS |
17975 |
18226 |
252 |
| intron |
17576 |
17974 |
399 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_002093920 |
GE20486 [Drosophila yakuba] ref|XP_002083857.1| GD13128 [Drosophila simulans] gb|EDW93632.1| GE20486 [Drosophila yakuba] gb|EDX09442.1| GD13128 [Drosophila simulans] |
1e-115 |
| InterPro |
IPR011304 |
L-lactate dehydrogenase |
|
| InterPro |
IPR022383 |
Lactate/malate dehydrogenase, C-terminal |
|
| InterPro |
IPR016040 |
NAD(P)-binding domain |
|
| InterPro |
IPR001236 |
Lactate/malate dehydrogenase, N-terminal |
|
| InterPro |
IPR001557 |
L-lactate/malate dehydrogenase |
|
| InterPro |
IPR015955 |
Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal |
|
| InterPro |
IPR018177 |
L-lactate dehydrogenase, active site |
|
| Gene Ontology(BP) |
GO:0005975 |
carbohydrate metabolic process |
|
| Gene Ontology(BP) |
GO:0006096 |
glycolysis |
|
| Gene Ontology(BP) |
GO:0044262 |
cellular carbohydrate metabolic process |
|
| Gene Ontology(BP) |
GO:0055114 |
oxidation-reduction process |
|
| Gene Ontology(CC) |
GO:0005737 |
cytoplasm |
|
| Gene Ontology(MF) |
GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
|
| Gene Ontology(MF) |
GO:0000166 |
nucleotide binding |
|
| Gene Ontology(MF) |
GO:0004459 |
L-lactate dehydrogenase activity |
|
| Gene Ontology(MF) |
GO:0003824 |
catalytic activity |
|
| Gene Ontology(MF) |
GO:0016491 |
oxidoreductase activity |
|
| Pfam |
PF00056.18 |
lactate/malate dehydrogenase, NAD binding domain |
1.4e-40 |
| Pfam |
PF02056.11 |
Family 4 glycosyl hydrolase |
7.4e-06 |
| Pfam |
PF11975.3 |
Family 4 glycosyl hydrolase C-terminal domain |
0.084 |
| Pfam |
PF03721.9 |
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain |
0.00033 |
| Pfam |
PF02254.13 |
TrkA-N domain |
0.072 |
| Pfam |
PF02737.13 |
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain |
0.017 |
| Pfam |
PF02866.13 |
lactate/malate dehydrogenase, alpha/beta C-terminal domain |
1.9e-30 |
| Pfam |
PF01210.18 |
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus |
0.0016 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. melpomene |
HMEL007279-PA |
| P. humanus |
PHUM581610-PA |
| P. vanderplanki |
Pv.07029 |
| C. quinquefasciatus |
CPIJ014454 |
| H. sapiens |
ENSP00000379385 |
| H. sapiens |
ENSP00000395337 |
| M. musculus |
ENSMUSG00000063229 |
| P. vanderplanki |
Pv.10074 |
| D. melanogaster |
FBgn0001258 |
| H. sapiens |
ENSP00000229319 |
| A. aegypti |
AAEL012014 |
| D. plexippus |
DPOGS202991PA |
| H. sapiens |
ENSP00000302393 |
| H. sapiens |
ENSP00000438241 |
| A. mellifera |
GB13882-PA |
| N. vitripennis |
NV16815-PA |
| H. sapiens |
ENSP00000379386 |
| H. sapiens |
ENSP00000437783 |
| H. sapiens |
ENSP00000280706 |
| H. sapiens |
ENSP00000445331 |
| H. sapiens |
ENSP00000379516 |
| H. sapiens |
ENSP00000368722 |
| S. invicta |
SI2.2.0_11768 |
| A. mellifera |
GB17148-PA |
| A. gambiae |
AGAP004880 |
| H. sapiens |
ENSP00000445175 |
| N. vitripennis |
NV16814-PA |
| H. sapiens |
ENSP00000406172 |
| M. musculus |
ENSMUSG00000030246 |
| C. quinquefasciatus |
CPIJ016131 |
| H. sapiens |
ENSP00000439555 |
| M. musculus |
ENSMUSG00000030851 |
| H. sapiens |
ENSP00000280704 |
| T. castaneum |
TC003922 |
| B. mori |
BGIBMGA012336-TA |