MidgeBase gene description page [Pn.12074]
Outline
| Gene ID | Pn.12074 |
| Type | Protein coding gene |
| Scaffold | PnScaf15449 |
| Start | 4217 |
| End | 9255 |
| Direction | + |
Sequence
Transcript: 2388 (bp)
ATGCCATTAGCTGGAAAAACATTAAATATATGGCCAACAAAACAAGAAGTCGCGAGCACATCTCAGCAATTACAAGGCTTAGAGATGGTCGTCGACGATGGATCTGTCATCAAATATCCACAGAATACGATCAATATTAATATTAATAACAATAACAATAATAACTCAATGGATAAGCTGCAAATTTCTGGACACGACGATGACTCCGACGACGTCGAGATGAAGTCCGATGACCTAGTCGTCGAGGTAAAGGATCTCGTCAAGGACGGTCACGAGAAGGCCGATCCCTCGCAGTTCGAGCTGCTCAAAGTGCTCGGCGAGGGCAGCTTCGGGAAGGTGTTTCTCGTGCGGAAGATTGTCGGCCTCGACGCCGGAACGTTGTACGCCATGAAGGTGCTGAAGAAGGCAACTCTCAAAGTCAAGGACCGCATGCGGTCGACCAACGAGCGGAACATCCTCGCCGACATCGCGGTGGGACACTCGTTTATCGTGAAGCTTCACTACGCCTTTCAAACGCCCGGCAAACTCTATCTCATTCTTGACTTCCTACGCGGCGGTGATTTGTTCACGCGATTGAGCAAGGAGGTCATGTTTACAGAGGAGGATGTCAAGTTTTACCTCGCCGAGCTTGCACTCGCTTTAAATCATCTTCACTCACTCGGAATTATTTATAGAGATTTAAAGCCGGAGAATATTCTACTGGACGCCGACGGTCACATTGCGCTGACGGACTTTGGGCTGTCGAAAATTCCGCTCGGAGACTCAAAAACCTACAGCTTCTGCGGAACAGTCGAATATATGGCGCCCGAAGTTGTCAATCGAAAAGGTCATACCTTCGCTGCAGATTGGTGGAGCTTCGGAGTGCTTATGTATGAGATGCTCACAGGAAATCTGCCGTTCCACGGAACAAACAGACAGGACACGATGAATCAAATTTTGAAGACAAAATTGGGCATGCCAGAGAACCTGTCGCCCGAGGCTCAGTCACTGCTGCGCGCTCTCTTCAAGAGAAATCCCCAGAACCGGCTCGGCGCCGGCTCGAATGGCATCGAGGACATTAAGCGGCACGAGTTCTTCGCGACAATCGATTGGGACGCGCTGCTGGCGAAGAAAGTGCGAGCGCCGTTCATCCCCAGTGTTTCGCGTGCCGACGACACATTCTACTTCGACTCGGACTACACGACACGCGATCCGCACGACTCGCCCAGCGTGCCGGTGTCGGCGAGTGCCCACGAAATTTTCCGAGGATTCTCCTTCGTCGCGCCGTGCCTGCTTGACGAGGGCGAAGACGAGGCCGGTGCCATGAACGTCAACAACAACGAGCGACAGTCGTCATTCCAGTCTTATGAAATTCCCGGCGTTCAGCCACATTCCATACACGACGAGTACCAGCTGAAGGAGGTCCTCGGCAGGGGCACGTTCTCGGTGTGTAAGCTTTGCGAGCACAAGACGACGAAGAAACAATATGCCGTGAAAATTATCGACAAATCGCGTCACGATTGCAGGGAGGAGGTTGATATTCTGCTGAGATACGGCAACCATCCGAACATCGTTACGCTCTATCGTGTCTTTGAGGATCCGCCATCTCGCTCCGTGTACTTAATTATGGAATATTTAAAAGGAGGAGAATTGCTCGATCGAATTTTGTCAATACAGTTTAGTGAGCAGGAGTCTGCAGCTGTCCTCAAGACTGTCGTCTCTGCCGTCTCATATCTCCATGACCACGGTGTCGTTCACAGGGATTTAAAGCCGTCAAACCTTCTCTATGCTTCCATTAATCATACGCCCGACTCGTTGCGACTGTGTGATCTGGGCTTCGCAAAGCAGCTGAGAGCCGACAACGGTCTACTGATGACTCCGTGCTACACGGCCAACTTCGTGGCGCCCGAGGTGCTGAAGAGGCAGGGCTACGATCAACTTTGTGATATCTGGTCATTGGGCGTCCTTCTCTACATCACGCTGAGTGGTCGCACGCCTTTCGCAAGCACGCCCAACGACGAGCCCGAAACGATCCTCAAGCGAATCGGAAGCGGTCAGATTGACTTGGAGAACGGCCGCTGGGCGTCGATTTCGATCGAGGCGAAGGAATTGATAAGTCACATGATGCACATCGTTCCATCGAAGCGTCCGACGGCGGCGCAAATCCTCAGACATCAGTGGACCGTGCGACAGTCGCACGCCTTCGAGTTGCGGTCGCAGCAAACGTCGTCACACTCGCTGCACCATGTGATGCAAAAGCCCACGACAAAGGACATCATCGAGATAAAGGGAGCTGTAAATGCGACATTCCGAGCGATAAACTCGCCGCAGGCCATGAACATCGTCGGCCCCGTCACCATGAGCGAGCTGGCACGTCGACGAAGACGAGGCGCCGAGAAAGGGCACAAC
Protein: 796 (aa)
MPLAGKTLNIWPTKQEVASTSQQLQGLEMVVDDGSVIKYPQNTINININNNNNNNSMDKLQISGHDDDSDDVEMKSDDLVVEVKDLVKDGHEKADPSQFELLKVLGEGSFGKVFLVRKIVGLDAGTLYAMKVLKKATLKVKDRMRSTNERNILADIAVGHSFIVKLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALNHLHSLGIIYRDLKPENILLDADGHIALTDFGLSKIPLGDSKTYSFCGTVEYMAPEVVNRKGHTFAADWWSFGVLMYEMLTGNLPFHGTNRQDTMNQILKTKLGMPENLSPEAQSLLRALFKRNPQNRLGAGSNGIEDIKRHEFFATIDWDALLAKKVRAPFIPSVSRADDTFYFDSDYTTRDPHDSPSVPVSASAHEIFRGFSFVAPCLLDEGEDEAGAMNVNNNERQSSFQSYEIPGVQPHSIHDEYQLKEVLGRGTFSVCKLCEHKTTKKQYAVKIIDKSRHDCREEVDILLRYGNHPNIVTLYRVFEDPPSRSVYLIMEYLKGGELLDRILSIQFSEQESAAVLKTVVSAVSYLHDHGVVHRDLKPSNLLYASINHTPDSLRLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDQLCDIWSLGVLLYITLSGRTPFASTPNDEPETILKRIGSGQIDLENGRWASISIEAKELISHMMHIVPSKRPTAAQILRHQWTVRQSHAFELRSQQTSSHSLHHVMQKPTTKDIIEIKGAVNATFRAINSPQAMNIVGPVTMSELARRRRRGAEKGHN
| Type | Start | End | Length |
| CDS |
4217 |
4270 |
54 |
| CDS |
6402 |
7050 |
649 |
| CDS |
7153 |
7319 |
167 |
| CDS |
7414 |
8055 |
642 |
| CDS |
8144 |
8252 |
109 |
| CDS |
8344 |
8461 |
118 |
| CDS |
8542 |
8857 |
316 |
| CDS |
8920 |
9252 |
333 |
| intron |
4271 |
6401 |
2131 |
| intron |
7051 |
7152 |
102 |
| intron |
7320 |
7413 |
94 |
| intron |
8056 |
8143 |
88 |
| intron |
8253 |
8343 |
91 |
| intron |
8462 |
8541 |
80 |
| intron |
8858 |
8919 |
62 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_311835 |
AGAP003040-PA [Anopheles gambiae str. PEST] gb|EAA07892.5| AGAP003040-PA [Anopheles gambiae str. PEST] |
0.0 |
| InterPro |
IPR017441 |
Protein kinase, ATP binding site |
|
| InterPro |
IPR002290 |
Serine/threonine- / dual-specificity protein kinase, catalytic domain |
|
| InterPro |
IPR017892 |
Protein kinase, C-terminal |
|
| InterPro |
IPR011009 |
Protein kinase-like domain |
|
| InterPro |
IPR000961 |
AGC-kinase, C-terminal |
|
| InterPro |
IPR008271 |
Serine/threonine-protein kinase, active site |
|
| InterPro |
IPR000719 |
Protein kinase, catalytic domain |
|
| InterPro |
IPR020635 |
Tyrosine-protein kinase, catalytic domain |
|
| Gene Ontology(BP) |
GO:0006468 |
protein phosphorylation |
|
| Gene Ontology(MF) |
GO:0004713 |
protein tyrosine kinase activity |
|
| Gene Ontology(MF) |
GO:0004674 |
protein serine/threonine kinase activity |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0004672 |
protein kinase activity |
|
| Gene Ontology(MF) |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
|
| Pfam |
PF00069.20 |
Protein kinase domain |
1.1e-138 |
| Pfam |
PF06293.9 |
Lipopolysaccharide kinase (Kdo/WaaP) family |
1.5e-08 |
| Pfam |
PF10707.4 |
PhoP regulatory network protein YrbL |
1.6e-05 |
| Pfam |
PF01163.17 |
RIO1 family |
0.0024 |
| Pfam |
PF01636.18 |
Phosphotransferase enzyme family |
5.1e-08 |
| Pfam |
PF00433.19 |
Protein kinase C terminal domain |
9.3e-07 |
| Pfam |
PF07714.12 |
Protein tyrosine kinase |
1.5e-71 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| D. melanogaster |
FBgn0262866 |
| H. sapiens |
ENSP00000432945 |
| H. sapiens |
ENSP00000363281 |
| H. sapiens |
ENSP00000262752 |
| M. musculus |
ENSMUSG00000003644 |
| H. sapiens |
ENSP00000368884 |
| A. mellifera |
GB13245-PA |
| A. gambiae |
AGAP003040 |
| H. sapiens |
ENSP00000427015 |
| N. vitripennis |
NV11974-PA |
| H. melpomene |
HMEL015753-PA |
| H. sapiens |
ENSP00000422435 |
| H. melpomene |
HMEL011296-PA |
| S. invicta |
SI2.2.0_12747 |
| H. sapiens |
ENSP00000333896 |
| C. quinquefasciatus |
CPIJ011936 |
| H. sapiens |
ENSP00000440830 |
| D. melanogaster |
FBgn0020412 |
| P. vanderplanki |
Pv.13045 |
| A. gambiae |
AGAP006094 |
| H. sapiens |
ENSP00000440220 |
| M. musculus |
ENSMUSG00000021180 |
| H. sapiens |
ENSP00000294261 |
| H. sapiens |
ENSP00000265678 |
| P. vanderplanki |
Pv.07625 |
| P. humanus |
PHUM599900-PA |
| H. sapiens |
ENSP00000368865 |
| M. musculus |
ENSMUSG00000025665 |
| P. humanus |
PHUM508900-PA |
| C. quinquefasciatus |
CPIJ012176 |
| M. musculus |
ENSMUSG00000023809 |
| C. quinquefasciatus |
CPIJ014359 |
| H. sapiens |
ENSP00000363277 |
| N. vitripennis |
NV16126-PA |
| H. sapiens |
ENSP00000442803 |
| A. aegypti |
AAEL004474 |
| H. sapiens |
ENSP00000363283 |
| H. sapiens |
ENSP00000431651 |
| D. plexippus |
DPOGS205511PA |
| M. musculus |
ENSMUSG00000024952 |
| D. plexippus |
DPOGS203202PA |
| H. sapiens |
ENSP00000432281 |
| T. castaneum |
TC001074 |
| H. sapiens |
ENSP00000402787 |
| H. sapiens |
ENSP00000386050 |
| H. sapiens |
ENSP00000422484 |
| A. mellifera |
GB12043-PA |
| H. sapiens |
ENSP00000444837 |
| H. sapiens |
ENSP00000435412 |
| H. sapiens |
ENSP00000435580 |
| T. castaneum |
TC000021 |
| A. aegypti |
AAEL011145 |
| B. mori |
BGIBMGA011088-TA |
| H. sapiens |
ENSP00000261991 |