MidgeBase gene description page [Pn.11881]
Outline
| Gene ID | Pn.11881 |
| Type | Protein coding gene |
| Scaffold | PnScaf14803 |
| Start | 31464 |
| End | 39586 |
| Direction | - |
Sequence
Transcript: 4920 (bp)
ATGAGGTTTCTACTGTTGCTGCTGCTCGTGATTACGACTCGAGCGCAACGTCCACTAAATACCACAAACACATCAGGCGTTCTCACGGAGCCATTTTTCATCAAGCCAACGAGCACATCCACTTCCAAGTACCATCCGGAGCAGCGCGGAGGTGGCAATAATCCCTACTTCACGTCGAACGACTCGCCAGGAAAGGGCCGAGGCAGCGGCGACCGTCTCCTCGCTGTGCAGCCACACTCAAATGCCGAAATCTTCATTCCGTCGCTGAACGGCATCGTAGGCGAGCATGGCAGTGCCCAGTCGCAAGTGCCGGCAGCCAATCGACTGCACAAGGTCGTCAAGTCGCGCCAGAACAAATTCACGCAGCTCTACCAGCTCACAAAGAATCCCAACTTCACGCTCAACAATCCGAACCGCGAGAAGAGCCAGAACTACTCGTATGGCGGCCACCGCGGCGACTATCAGCACGGCAACATCATCACGTCCAAGAAGGAGGCGCGACCCGAGAAATTCTTCAGCGGACCCAACGACAACTTCGACACGCAGAAGACGTCGTGGTCGGACGGCCGGGCTTTCCAGGAAGTGCACAAACACTTGAGCAACAAGAACCACATGCACACGCCGTCGCCGCCCTCGTACACCGTCGACGACATCGATTTTGACGAGAAGCTCGGCGTGAAGTGCACCTTCGAGAAGCCGTGCGCGTGGACCTATGACACTGACGTGGTCGGCACAAATTTCGAGGTGACCACCGGAGCGAATCTCACCAACGCCAACATCACAGGCGTCATGCCGGGACCGTCGGCCGATAATTTGAAGGACGCGAACGGACACTTCCTGCACTTGCCGCTGACGCCGAACACGACTACACGCATACTGCGATCGCCCGTGTTTAGCTCGACGCGCGAGCGCTGCTACCTCGAGGTCTTCATGCATCAGAGCTCGATGGCCTCTGGCTCGATAAAGGTCGTCATCGAGCCGGCGGCGTCGCGCGAAAACTCCTGGGTGCCCGCTGAAATTGTCGGTGACGACTTGAGGAAGTGGAAGTATCATCATTTTGAGGTTGACAGGATAACAAACGACTTCCGCATTCTCTTCGAGATTGTTCCGAACGGCTTGGGCGGTGCATTGCGCGGCCACGTGAGCATCGACAACCTCAAGATGAGCAATTGTTTTGCTGATCCGCCGCGCAAGGACTCGTGCAAGCTCTCGCAAATCAAGTGCAGTCAGAGCAAGATTCCGGTGTGCATCGAGAACAACCGCATTTGCGACTTGGTGCAGGATTGCGACGACGCTGAGGACGAAAATCTCAATTGCGACAAGATACCGTTCGGAGGACTGTGCGACTTCGAGAACGGCAACTGCGGCTGGCAGAACTCGGGCAAGGCGATCATGGACTGGAAACGACACCTCGGGCCGACACCGACCGAGAAGACCGGGCCCGAGTTCGACCACACGTTCCAGCACACTAACAAGTCCGGCCACTATATGTTTGTAAATATGAACCAGCACGCCGACGACCCCGAGCGCAAAAACCTTGCCGGCTTCGCGAGCAACGCCATCATTAATTCGGTCGTGTTTAACCCGCCGCCGCCCTGCCACTCGAACGTCTCGTCGCCATACCACAACACATGCATGGCACGCCTCTTCGTCCACCAGTTCGGCCACAATCCCGGCAGCTTCAACGTGTCCGTTGTGGAGATGAAGGCGAAGGAGAACATCACGACCACGCTGTGGTGGAGCTCGCGTTCGATCGGCGACAAATGGGAGCGCGTTGACGTGGTGCTGCCGAACATTACGTCCAAGTACTACTTCCAGATCGAGGCGCGCAAAGGCATGCGGATCTATAGCGACGTCGCCATCGATGACTTCTCGATGAGTCCCGAGTGCTTCGGCTTCAACATTCCGGCCGAGCACCTTAACAACTACAACTACTGGGACCCGAGAATCGGCATTCACAAGAAACCCCATAGCGATTTTGTAGATAAGAAATTTTATGAACTCTCAACATGTGGTTCGCGTGGAATATTCGGACCCACACCTGAAGCTTGCTCAACTCACTATAATAATACTGAAATAATGAATCATGTGCGTGTGTCTGACAAAGTACCTTTCAAAGGCGTGCAAGTGTGGAAGGTGCCGAGTGAAGGCTACTACACAATAATAGCGAAAGGCGCAAGCGGCGGACTCGGCAGCGGCGGAGTGTCGTCATCGCGCGGAGCGATTGTGAGCTCAGTCATGGAGCTCCACAAGGACGAGGAGATTTATATCCTGGTCGGTCAGAAGGGCGAGAATGCGTGCATCAAGTCGATGGGCATTTCCGACGAGGGCTGTTCCCCAAAATTTCCCAAATACAACGACCACCCGAAGGACTCCGTCTCAATTATCAATCAACTGCGCAATGGCCTCCTCGAAAACGGAGCCGGCGGCGGCGGAGGAGCATCGTTTGTGTTTCTGCTGAATCAAGTGAACAAAGCCGTGCCGCTGATTGTGGCAGGCGGAGGTGGCGGTTTGGGAATCGGCCGCTATCTGGACGAGGACATTCAACAGGCTAAGGGAATCGTAATCGAGCGCGGCGACGTCAGTGGCCAGGTGGAGTACGACAATGGCGACTCTCTTGTCGCAGGACCGGGAGGCGGTTGGCGTCCGCGTCAGGACTCGGCGCTCGACTCTCACCACGGCGCATCGCTGCTGGAAGGTGCGCGTGGCGGAATCGCCTGCTACCAGACAGTCGGCCAGGATCACGGCTACGGAAATGGAGCGTTTGGCGGTGGCGGTGGCTCTTGTCAGTCGGGCGGCGGAGGCGGCGGTTATGCTGGCGGCAACTCGATGCTCAACTACACGACTAACTCGTCGGCAAACCCGAATGCATTCTCCACCAACGGCGAGGGCGGCTCTTCCTATTTGGGCCTTACGCGCAGCATCCACGAGCTCTCTTTCGTCTATCCGGGCTCGAACAGCGGCCACGGCTCAGTCATTCTCATTCCGGCCATCGAGGGATGCGGCTGCGATTACCGGTGTGTGGCGCTCGACGAATATCGCTCGCTCGTCGCCTGCATCTGTCCCGAGGGGTGGCGTCTCAAGCCCGACAACCTCACCTCATGCGAAATAATCGAAGAGGTCAACAATGACAACATTATAATCTACATACTCGTAGTTGTATCAGTCTTTTTAATCATCTCTCTTGTACTATTGATGTTGATGTTATATAATCGTTTCCAAAGAAGACGACAAGCGGAGATGCGCCACAAGATGCTTCTTGAACAAGAAGTTCAATTAAGTCGATTGCGACACACAGACGACTCAGCTTTAACTAATTTTAATCCAAATTATGGTTGTGATGGTATCTTGAATGGTGGAAATGTTGATGTTAAAAGTTTACCCCAAGTTGCGCGCGAAAGCCTGCGACTCGTCAAAGCCCTCGGACAAGGGGCATTTGGTGAGGTGTACCAAGGCCTTTATCGCCACCGCGATGGCGATACCGTCGAGATGCCTGTCGCTGTCAAAACCCTGCCCGAATTGTCGACCGGCCAAGCGGAGTCGGACTTCCTCATGGAGGCGGCAATCATGGCGAAGTTCAATCACCCGAACATTGTCCATCTCATTGGCGTGTGCTTTGACCGCCATCCGCGATTCATCGTGCTCGAGCTGCTCGCGGGCGGCGACCTGAAGAACTTTTTGCGCGAGGGCCGCAACAAACCCGAACGACCGTCGCCGCTGACGATGAAGGACTTGATTTTCTGCGCACTGGACGTCGCCAAGGGATGCCGCTACATGGAGAGCAAGCGCTTCATTCATCGTGACATCGCCGCCAGAAATTGCCTCCTCAGCAGCAAGGGTCCCGGTCGCGTCGTCAAAATTGCAGACTTCGGCATGGCGCGCGACATTTACCGGTCCGATTACTATCGCAAGGGCGGCAAGGCAATGCTGCCGATAAAATGGATGCCACCTGAGGCATTCTTGGACGGAATCTTCACGTCGAAGACAGACATCTGGAGCTATGGCGTGCTGTTGTGGGAGGTGTTTTCGCTCGGTCTAATGCCTTACACAGGCCTACCGAATCGTGACGTCATGCAGCTCGTCACGGGAGGAGGACGACTCGATGCACCGCCCGGATGTCCGCCAGCGATCTACCGCATCATGGCCGAGTGCTGGAACCCGACTCCCGAAGCCCGTCCAACCTTCTCGGTACTGCTCGAGCGACTGACCGCGTGCACGCAAGACCCCGAAATCATGAATGCACCGCTGCCGAGTTTCTTCCGCCCACAGTCGATGGAGCGCGACGCCACGATCATGCGGCCATCGGGCAACGATGACTTCTGCCTGCAGGTACCAAACTCGTCCGACTACTTGATCCCGCTGCCCGACTCGCGCGCCATCGCTGAGCGCTTACTCAATGAGGCGACGTGCGTCACACTGCCCGACTCGCTGCCCACCTATACACTCACCAACTCGCTCAAGATGCCCGACACCAACTGCTGGGAGACGTCCTTCTCGAATCCCGCCAAGATGAGCAACTCCGACAGCCTCGACGACCGCTTGATAAGTCTGGACACGCCGACGACGATCCAGCCTCCGCAGGCCTTCTGCAACAGTCCCGTGCAGACGCTTTCTTCGAACGCCGCTAACAACAACAACAACAATGTTAGCGGAAAGAACAGCGCGATCACACTCGACCCGGCCGCCCTTCAGCAGGGCTACGCGAATGTGAAGATGATGAACGGCGGCACGGACAAGCTAGAGGGCGACATGTCAAAGTTCAACGGCGGCTCGACGATGGTGATGATGAACAATAACAACGGAACGATTCCGAATGGCAACGGCATGCTTCCGAAAGACAAGAACTCGAACCAGCCGTTCTCGATACCCATGCAGGGCTACAACGAGAGCTTCAAGGAAAACCACGCCGAGATCAGCTGC
Protein: 1640 (aa)
MRFLLLLLLVITTRAQRPLNTTNTSGVLTEPFFIKPTSTSTSKYHPEQRGGGNNPYFTSNDSPGKGRGSGDRLLAVQPHSNAEIFIPSLNGIVGEHGSAQSQVPAANRLHKVVKSRQNKFTQLYQLTKNPNFTLNNPNREKSQNYSYGGHRGDYQHGNIITSKKEARPEKFFSGPNDNFDTQKTSWSDGRAFQEVHKHLSNKNHMHTPSPPSYTVDDIDFDEKLGVKCTFEKPCAWTYDTDVVGTNFEVTTGANLTNANITGVMPGPSADNLKDANGHFLHLPLTPNTTTRILRSPVFSSTRERCYLEVFMHQSSMASGSIKVVIEPAASRENSWVPAEIVGDDLRKWKYHHFEVDRITNDFRILFEIVPNGLGGALRGHVSIDNLKMSNCFADPPRKDSCKLSQIKCSQSKIPVCIENNRICDLVQDCDDAEDENLNCDKIPFGGLCDFENGNCGWQNSGKAIMDWKRHLGPTPTEKTGPEFDHTFQHTNKSGHYMFVNMNQHADDPERKNLAGFASNAIINSVVFNPPPPCHSNVSSPYHNTCMARLFVHQFGHNPGSFNVSVVEMKAKENITTTLWWSSRSIGDKWERVDVVLPNITSKYYFQIEARKGMRIYSDVAIDDFSMSPECFGFNIPAEHLNNYNYWDPRIGIHKKPHSDFVDKKFYELSTCGSRGIFGPTPEACSTHYNNTEIMNHVRVSDKVPFKGVQVWKVPSEGYYTIIAKGASGGLGSGGVSSSRGAIVSSVMELHKDEEIYILVGQKGENACIKSMGISDEGCSPKFPKYNDHPKDSVSIINQLRNGLLENGAGGGGGASFVFLLNQVNKAVPLIVAGGGGGLGIGRYLDEDIQQAKGIVIERGDVSGQVEYDNGDSLVAGPGGGWRPRQDSALDSHHGASLLEGARGGIACYQTVGQDHGYGNGAFGGGGGSCQSGGGGGGYAGGNSMLNYTTNSSANPNAFSTNGEGGSSYLGLTRSIHELSFVYPGSNSGHGSVILIPAIEGCGCDYRCVALDEYRSLVACICPEGWRLKPDNLTSCEIIEEVNNDNIIIYILVVVSVFLIISLVLLMLMLYNRFQRRRQAEMRHKMLLEQEVQLSRLRHTDDSALTNFNPNYGCDGILNGGNVDVKSLPQVARESLRLVKALGQGAFGEVYQGLYRHRDGDTVEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHPNIVHLIGVCFDRHPRFIVLELLAGGDLKNFLREGRNKPERPSPLTMKDLIFCALDVAKGCRYMESKRFIHRDIAARNCLLSSKGPGRVVKIADFGMARDIYRSDYYRKGGKAMLPIKWMPPEAFLDGIFTSKTDIWSYGVLLWEVFSLGLMPYTGLPNRDVMQLVTGGGRLDAPPGCPPAIYRIMAECWNPTPEARPTFSVLLERLTACTQDPEIMNAPLPSFFRPQSMERDATIMRPSGNDDFCLQVPNSSDYLIPLPDSRAIAERLLNEATCVTLPDSLPTYTLTNSLKMPDTNCWETSFSNPAKMSNSDSLDDRLISLDTPTTIQPPQAFCNSPVQTLSSNAANNNNNNVSGKNSAITLDPAALQQGYANVKMMNGGTDKLEGDMSKFNGGSTMVMMNNNNGTIPNGNGMLPKDKNSNQPFSIPMQGYNESFKENHAEISC
| Type | Start | End | Length |
| CDS |
31467 |
31853 |
387 |
| CDS |
31974 |
32404 |
431 |
| CDS |
32502 |
32658 |
157 |
| CDS |
32774 |
32853 |
80 |
| CDS |
33004 |
33452 |
449 |
| CDS |
33708 |
33915 |
208 |
| CDS |
34014 |
34112 |
99 |
| CDS |
34184 |
34519 |
336 |
| CDS |
34953 |
35090 |
138 |
| CDS |
35173 |
35350 |
178 |
| CDS |
35703 |
36000 |
298 |
| CDS |
36090 |
36255 |
166 |
| CDS |
36904 |
37578 |
675 |
| CDS |
37956 |
38203 |
248 |
| CDS |
38517 |
39586 |
1070 |
| intron |
31854 |
31973 |
120 |
| intron |
32405 |
32501 |
97 |
| intron |
32659 |
32773 |
115 |
| intron |
32854 |
33003 |
150 |
| intron |
33453 |
33707 |
255 |
| intron |
33916 |
34013 |
98 |
| intron |
34113 |
34183 |
71 |
| intron |
34520 |
34952 |
433 |
| intron |
35091 |
35172 |
82 |
| intron |
35351 |
35702 |
352 |
| intron |
36001 |
36089 |
89 |
| intron |
36256 |
36903 |
648 |
| intron |
37579 |
37955 |
377 |
| intron |
38204 |
38516 |
313 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001648125 |
leukocyte receptor tyrosine protein kinase [Aedes aegypti] gb|EAT44705.1| leukocyte receptor tyrosine protein kinase [Aedes aegypti] |
0.0 |
| InterPro |
IPR002172 |
Low-density lipoprotein (LDL) receptor class A repeat |
|
| InterPro |
IPR017441 |
Protein kinase, ATP binding site |
|
| InterPro |
IPR002290 |
Serine/threonine- / dual-specificity protein kinase, catalytic domain |
|
| InterPro |
IPR000998 |
MAM domain |
|
| InterPro |
IPR023415 |
Low-density lipoprotein (LDL) receptor class A, conserved site |
|
| InterPro |
IPR001245 |
Serine-threonine/tyrosine-protein kinase catalytic domain |
|
| InterPro |
IPR011009 |
Protein kinase-like domain |
|
| InterPro |
IPR002011 |
Tyrosine-protein kinase, receptor class II, conserved site |
|
| InterPro |
IPR000719 |
Protein kinase, catalytic domain |
|
| InterPro |
IPR008266 |
Tyrosine-protein kinase, active site |
|
| InterPro |
IPR020635 |
Tyrosine-protein kinase, catalytic domain |
|
| InterPro |
IPR008985 |
Concanavalin A-like lectin/glucanase |
|
| Gene Ontology(BP) |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
|
| Gene Ontology(BP) |
GO:0006468 |
protein phosphorylation |
|
| Gene Ontology(CC) |
GO:0016020 |
membrane |
|
| Gene Ontology(MF) |
GO:0004713 |
protein tyrosine kinase activity |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0004672 |
protein kinase activity |
|
| Gene Ontology(MF) |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
|
| Gene Ontology(MF) |
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
|
| Pfam |
PF00069.20 |
Protein kinase domain |
3.5e-40 |
| Pfam |
PF12810.2 |
Glycine rich protein |
3.4e-16 |
| Pfam |
PF00629.18 |
MAM domain |
4.9e-60 |
| Pfam |
PF07714.12 |
Protein tyrosine kinase |
1.8e-91 |
| Pfam |
PF00057.13 |
Low-density lipoprotein receptor domain class A |
7.4e-05 |
| Pfam |
PF01484.12 |
Nematode cuticle collagen N-terminal domain |
0.017 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000263800 |
| H. melpomene |
HMEL003801-PA |
| P. humanus |
PHUM583770-PA |
| C. quinquefasciatus |
CPIJ019761 |
| D. melanogaster |
FBgn0040505 |
| H. sapiens |
ENSP00000347293 |
| A. mellifera |
GB14602-PA |
| C. quinquefasciatus |
CPIJ010280 |
| S. invicta |
SI2.2.0_07727 |
| H. sapiens |
ENSP00000392196 |
| H. sapiens |
ENSP00000373700 |
| M. musculus |
ENSMUSG00000027297 |
| A. aegypti |
AAEL003969 |
| B. mori |
BGIBMGA000152-TA |
| D. plexippus |
DPOGS205518PA |
| A. gambiae |
AGAP012070 |
| N. vitripennis |
NV14367-PA |
| T. castaneum |
TC002114 |
| M. musculus |
ENSMUSG00000055471 |
| P. vanderplanki |
Pv.04037 |
| H. sapiens |
ENSP00000458111 |