MidgeBase gene description page [Pn.11705]
Outline
| Gene ID | Pn.11705 |
| Type | Protein coding gene |
| Scaffold | PnScaf14314 |
| Start | 14380 |
| End | 18580 |
| Direction | - |
Sequence
Transcript: 3627 (bp)
ATGTCACTAAAATTAACGAAGGCTGACTTAGAACGCATTCCGGAGCACATTAATTTCTCGCAAGAGGAAGAAAACGTCCTCAAGTACTGGAACGAGGAGAAGGTCTTCGAGAATTGTCTCAAGCAGTCGAAGGGAAAACCTCGATATACCTTCTACGATGGACCTCCTTTTGCGACTGGATTGCCTCATTACGGTCACATTTTAGCCGGCACAATCAAAGACATTGTTACTAGGTATGCACATCAGCAGGGATATCACGTTGAGCGACGCTTTGGTTGGGATTGCCACGGACTTCCAGTCGAATTCGAAATTGACAAGACTCTCGGCATAAAAGGACCCGATGACGTCCTTAAAATGGGCATTGCCGCCTACAACAACGAGTGCCGGAAGATTGTCATGCGATATGCCAACGAATGGGAGCAAATTGTCGGCCGTTTGGGAAGATGGATTGATTTCAAGAACGACTACAAGACTCTCTATCCCTGGTTCATGGAGTCGGTGTGGTGGGTGTTTAAGCAGCTGTACACGAAGGGCCTCGTCTACCAAGGCGTCAAAGTCATGCCGTACAGTACTGCATGCACGACGCCGCTCTCGAATTTCGAGTCGGGTCAGAACTATAAGGACGTGCAGGATCCGATGGTTTTCGTCTCGATGCCTCTAGTCGGCGACAAGGACAAGGCTGCCTTGATCGTGTGGACCACAACGCCCTGGACACTGCCCTCAAACATGGCCTGCTGCGTCAATCCCGAACTTACGTACATAAAAGTGAAGGAGAAGACGACCGGCGCCGTTTACATCATAATGGAGTCGCGAACCGAGTACGTCTTTAAAACGGCCGACGCCGTGGAAGTGCTCGACAAGTTCCCCGGATCCAAGCTGAAGGGACTGTGTTACGAGCCGCCATTCGATTATTTCAAGAAATACAGCAACGTCGCGTTTCGCGTGTTGTGCGACGGCTACGTCACAGAAGGCTCCGGCACGGGTGTCGTCCATCAGGCACCGTACTTCGGCGAGGACGATTACCGCGTTTGCCTCGCGCACGACGTCATCAAGAGAGACCAGGAGGTCATTTGCCCGCTCGACGCAAACGGCCGCTTCACCAAGGAGGTGACCGACTTCGAGGGCCAGTACGTGAAGGACGCCGACAAGAACATCATCAAGCTGCTGAAGGAGAAAGGCCGCTTGGTGCGCTCGGGCCAGCACCTCCATAGCTACCCCTTCTGCTGGCGCTCGGACACGCCGCTCATCTACAAGGCGGTGCCGTCGTGGTTTGTGCGCGTGGAGCACATGACTAAGCAGCTGCTCGCGAGCTGCGCGCAAACCTACTGGGTGCCCGACAACGTCAAGGAGAAGCGCTTCGGCAACTGGCTGAAGGAGGCGCGCGACTGGGCCATCAGCCGCAACCGCTACTGGGGCACGCCCATCCCGCTGTGGATGTCGCCGTCGGGCGACGAGGTCGTGTGCATCGGCTCGATCGAGGAGCTCGAGAAGCTGTCGGGCGTGAAGGTCACGGACCTGCATCGCGAGTTCGTCGACGTCATTGAGATTCCGTCGAAAATTCCCGGAAATCCGCCGCTGCGACGCGTCCCCGAGGTCTTCGACTGCTGGTTCGAGTCGGGCTCGATGCCCTACGCTCAGCAGCACTATCCGTTCGAGAATCCGCAGGACTTCATCAACAACTTCCCCGCCGATTTCATCGCCGAGGGCATCGACCAGACCCGTGGCTGGTTCTACACGCTTCTCGTCATCTCGACCGCCCTTTTCAACAAACCGCCGTTCAAGAATTTGATCGCCAACGGCCTTGTGCTCGCCGCCGACGGCCAGAAGATGTCGAAGCGCAAGCAAAACTATCCCGATCCGAAGCTGCTGGTCGACAAATATGGCGCCGATGCGGTGCGCTTGTATCTCATAAACTCGCCCGTCGTCCGCGCCGAAAATCTCAAGTTCAAGGAGGAGGGCGTGCGGGACATCATCAAGGATGTCTTTCTGCCGTGGTTCAACGCCTACCGCTTTCTGTTCCAGAACATCGATCGGCTCGAGAAGGAGGAGAAGGTCGTGTACAAGTTCGATGCGAAGCGTCGGGAGCGCGAGGGATCCGACAACGTCATGGACGTGTGGATTGCGAGCTTCAAGGAGTCGCTGCTCGACTTTATTGCGCGCGAAATGAAGGCCTATCGACTCTATACGGTCGTGCCGCGTCTCACAAAGTTCATCGATCAGCTGACCAACTGGTACGTGCGCATGAACCGCCGTCGTCTGAAGGGAGAGGGCGGCTTGAAGGACTGCTACAACGCTCTCGACACGCTCTACGACGTCCTCATGGCGATGGTCAAAATGATGGCGCCCTTCACGCCCTTCCTCACCGAGTACATGTACCAGCGCTTGCGGCTGTTGGACGAGAAGGCCTCCAACGGAAGCGTCCACTACGAGATGATGCCGAGCGCAAACATGAGCTCGATCAACGTGAACATCGAGCGTGCCGTTGCTCGCATGCAGACAGTCGTCGAACTCGGCCGTGTGATGCGCGACCGCCGCACGGTGCCCATCAAATATCCGCTCACCGAGGTGGTCGTCATTCACCAGCAGCAGGAGTACCTCGACGACATCAACTCGCTGCAGCAGTTCATAACCGGCGAGCTCAACGTGCGCTCGATTGTGCTGAGCCAGGACAAAAAGAAGTACGGCATCACGCTGCGGGCCGAGGCCGACCACAAGCTGCTGGGCATTCGACTCAAAAACGAGGCGAAAGTGGTCGCGCAGAAAATCAAGGAGCTGACCGACGGCGAGATTCAGGAGCAGACGAAGCGCGGCTGGTTCGAAGTCGCCGGCCATCGCTTGGAGACGAACGAGGTTCGCGTCATTTATCAGTTTGGCGGCGACACGGCTGGAAAAGATGCGGACTACGAGGCGCACAGCGACAACGACGTGCTGGTCTTGCTGAACATGAAGCCGAACCAGGAGCTGGTCGACGAGGGCCTTGCGCGCGAAATCATCAATCGAGTGCAGAAGCTGAAGAAGAAGGCGAAGCTGATTCCGACCGATGCCGTCATCATCACTTTCAGCGTGTCGAATGAGAAAAGCGACGTGCTGAGAATCGCCAAGAGCCATCAAGCGTACATCGAAAATGTCATCAAGTCGAAGTTCGTGCAGCACGATGCGGCGGCCGAGAAGCGGGAAATCTTGATTGAGGAGACGCAGGAGTTGAAGGACGTGCAGTTGGTTCTCAAAATCACCGGCATGAGCGAGCGAGCGGTGCCGAAATTGCCGTGGATAAATATTGCGGTCGCTGACGATGTTGAGCTGCGATATGTTGAGAACAAGACGTTGCGCTCGGCGACCTTCAATCTCGTTGACTTCAATGGAAATCTGCTCACTTTTGATCGACTGAAGGAGGAAATTGAGAATGTTTTTGGAATTTATGGGACTGGCTACGAAGTCACGACGTCCGATAGGAAGCCGCTTGGCGGTGTGACGAAGGAGCTGGCTGGAAAGACGCTGTTTGTCGTTAGGAATGAAAAGAGCAAAGTAGGCGAGAATCTGCTCAACAAAAACTATCCGTTTAGCAAATTTACGAACAAAACCGTCAACGGAAAGGAGGTCACGGTTTATCTTGAGAATCCTTCGAAC
Protein: 1209 (aa)
MSLKLTKADLERIPEHINFSQEEENVLKYWNEEKVFENCLKQSKGKPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQQGYHVERRFGWDCHGLPVEFEIDKTLGIKGPDDVLKMGIAAYNNECRKIVMRYANEWEQIVGRLGRWIDFKNDYKTLYPWFMESVWWVFKQLYTKGLVYQGVKVMPYSTACTTPLSNFESGQNYKDVQDPMVFVSMPLVGDKDKAALIVWTTTPWTLPSNMACCVNPELTYIKVKEKTTGAVYIIMESRTEYVFKTADAVEVLDKFPGSKLKGLCYEPPFDYFKKYSNVAFRVLCDGYVTEGSGTGVVHQAPYFGEDDYRVCLAHDVIKRDQEVICPLDANGRFTKEVTDFEGQYVKDADKNIIKLLKEKGRLVRSGQHLHSYPFCWRSDTPLIYKAVPSWFVRVEHMTKQLLASCAQTYWVPDNVKEKRFGNWLKEARDWAISRNRYWGTPIPLWMSPSGDEVVCIGSIEELEKLSGVKVTDLHREFVDVIEIPSKIPGNPPLRRVPEVFDCWFESGSMPYAQQHYPFENPQDFINNFPADFIAEGIDQTRGWFYTLLVISTALFNKPPFKNLIANGLVLAADGQKMSKRKQNYPDPKLLVDKYGADAVRLYLINSPVVRAENLKFKEEGVRDIIKDVFLPWFNAYRFLFQNIDRLEKEEKVVYKFDAKRREREGSDNVMDVWIASFKESLLDFIAREMKAYRLYTVVPRLTKFIDQLTNWYVRMNRRRLKGEGGLKDCYNALDTLYDVLMAMVKMMAPFTPFLTEYMYQRLRLLDEKASNGSVHYEMMPSANMSSINVNIERAVARMQTVVELGRVMRDRRTVPIKYPLTEVVVIHQQQEYLDDINSLQQFITGELNVRSIVLSQDKKKYGITLRAEADHKLLGIRLKNEAKVVAQKIKELTDGEIQEQTKRGWFEVAGHRLETNEVRVIYQFGGDTAGKDADYEAHSDNDVLVLLNMKPNQELVDEGLAREIINRVQKLKKKAKLIPTDAVIITFSVSNEKSDVLRIAKSHQAYIENVIKSKFVQHDAAAEKREILIEETQELKDVQLVLKITGMSERAVPKLPWINIAVADDVELRYVENKTLRSATFNLVDFNGNLLTFDRLKEEIENVFGIYGTGYEVTTSDRKPLGGVTKELAGKTLFVVRNEKSKVGENLLNKNYPFSKFTNKTVNGKEVTVYLENPSN
| Type | Start | End | Length |
| CDS |
14383 |
15778 |
1396 |
| CDS |
16178 |
17957 |
1780 |
| CDS |
18055 |
18362 |
308 |
| CDS |
18438 |
18580 |
143 |
| intron |
15779 |
16177 |
399 |
| intron |
17958 |
18054 |
97 |
| intron |
18363 |
18437 |
75 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001656071 |
isoleucyl tRNA synthetase [Aedes aegypti] gb|EAT48591.1| isoleucyl tRNA synthetase [Aedes aegypti] |
0.0 |
| InterPro |
IPR014729 |
Rossmann-like alpha/beta/alpha sandwich fold |
|
| InterPro |
IPR001412 |
Aminoacyl-tRNA synthetase, class I, conserved site |
|
| InterPro |
IPR009008 |
Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing domain |
|
| InterPro |
IPR013155 |
Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding |
|
| InterPro |
IPR023586 |
Isoleucyl-tRNA synthetase, type 2 |
|
| InterPro |
IPR002300 |
Aminoacyl-tRNA synthetase, class Ia |
|
| InterPro |
IPR002301 |
Isoleucyl-tRNA synthetase |
|
| InterPro |
IPR009080 |
Aminoacyl-tRNA synthetase, class 1a, anticodon-binding |
|
| Gene Ontology(BP) |
GO:0006418 |
tRNA aminoacylation for protein translation |
|
| Gene Ontology(BP) |
GO:0006428 |
isoleucyl-tRNA aminoacylation |
|
| Gene Ontology(CC) |
GO:0005737 |
cytoplasm |
|
| Gene Ontology(MF) |
GO:0002161 |
aminoacyl-tRNA editing activity |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0000166 |
nucleotide binding |
|
| Gene Ontology(MF) |
GO:0004812 |
aminoacyl-tRNA ligase activity |
|
| Gene Ontology(MF) |
GO:0004822 |
isoleucine-tRNA ligase activity |
|
| Pfam |
PF00133.17 |
tRNA synthetases class I (I, L, M and V) |
1.6e-226 |
| Pfam |
PF08264.8 |
Anticodon-binding domain of tRNA |
2.1e-23 |
| Pfam |
PF01406.14 |
tRNA synthetases class I (C) catalytic domain |
0.00079 |
| Pfam |
PF09334.6 |
tRNA synthetases class I (M) |
6.4e-20 |
| Pfam |
PF09178.5 |
Domain of unknown function (DUF1945) |
0.052 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000364794 |
| P. humanus |
PHUM515270-PA |
| H. sapiens |
ENSP00000378922 |
| H. sapiens |
ENSP00000415020 |
| T. castaneum |
TC010772 |
| D. melanogaster |
FBgn0027086 |
| M. musculus |
ENSMUSG00000037851 |
| D. plexippus |
DPOGS204818PA |
| A. aegypti |
AAEL000388 |
| A. mellifera |
GB12270-PA |
| C. quinquefasciatus |
CPIJ016361 |
| A. gambiae |
AGAP002101 |
| P. vanderplanki |
Pv.09354 |
| H. sapiens |
ENSP00000406448 |
| P. vanderplanki |
Pv.12194 |
| P. vanderplanki |
Pv.09355 |
| N. vitripennis |
NV14307-PA |
| B. mori |
BGIBMGA001558-TA |
| H. melpomene |
HMEL007425-PA |
| S. invicta |
SI2.2.0_04230 |