MidgeBase gene description page [Pn.09459]
Outline
| Gene ID | Pn.09459 |
| Type | Protein coding gene |
| Scaffold | PnScaf9739 |
| Start | 13103 |
| End | 33396 |
| Direction | + |
Sequence
Transcript: 3834 (bp)
ATGAAGACGCAAAGTAGTCTCGAAGTACCTAAGCAGGTGCGCTCCGCGTCGTTCGACGAGATAAAGCTCGAGTCGCAGCGAGCCGCTCAGTTCCTCCTCACGAATCAGTCGTCGACGGACTCGCAGTCGACGCTGCTCACCGTTCCGAATAGCCAGCGATCGCGCAGCTTCGACTCGGCCGGCATCGAGCCGTCCGATGTGAATGCCTCGTTCCTGGACATCCCGCGACAGCGCTTTCGACGGAAGTCGAGCGCCAAGGCGCCCGTTTGCATTCACTGTCAGTATGTGGAGGAGCAGCGGAAGCGCGGCAGCACGGCCGGCTTCTACTTCGACGCGCAGGAGTTCCGCTCGCTCACCTACTCGAACTCGTCGTCGGACGAGTCGTCGACTTCGGAGAGCGAGGACACGACGACGGACGAGCCGCCCGACGGCGACGCCGACGACGACGACATCGACGTCGACTATTACTTTCAGAATCAAACGACCCTCCTTCTACCTTCGCCATGTAGCATTACGTTTACACTGTCGCCAACGAATTGTGATTATCCAGCCTTTCCCCTACCAGGCCTCGTGCCGCCCAGCATAAGTTCACCGCCAGCAATGCCTTCGACACCGCCCGTCTTTCCCACCTCGCCGACGATAGAGCTCACGCACGACGTCGACGAGATCGAGGTGCCCGGGCCGCGGCAGAGGCGCCGCTCCATTTCGCGCCAGGAGGCGATCTTCGTCGAGCCCACCGGCTCCTCGCTCGAGAATGTCTCCAACTCGTCCGACGTCGAGCAGGCGACGGTGACGGCGTCGGCGCCGCAACCGTCCTCAACGCCACCGCTGACGACGAAAGAAAGCGACGAGAGCGAGCGACGGCACTCGGACATTCCGAAGGCATCGGAGCCATTTGTTCGTGATATTTTCCTCACCGTGCCTGATCTGAAGCGGGATCGCGCGGCGTCCGTTGACTCGTGCTTCACGAAAGTCACGTCGGCCGCGAAGACGGAGGAGGTTCAGCCGCCCGAGGGCGACCTCAACCTGCTCACCGTGCCGAACAGCGGTGCCGTGCGATCTCGAAGCGTCGACATCGTTCTTCCGACCGAACAGCAAGCACGCTACAAAGCACTTGCTTTAGCGGGACCAGCTAGCAATATATACAATAAAGGAAAACCAGGCGACAACTCGGGAACGCGGCAAATAAGAAACACACCGGATTGGACGGAAAACGCTGTGTCAGGAGATCACTTGTGGGTGCCTACATCAGTATCTGGAGATTGTTGCTATATCGGTGATAATGACTGTACAAAACATGGACCAAGAATGAAATGTTCAGCATGCAAAATCATCGCGCACGCCAACTGCATATCGGTGCTAATGGAGCGCTCGCAGCTGGCATGCAAGCCGACGTTTCGCGACGTCGGCGTTCGTCAGTACCGCGAGCAGACGCGAACTCACCACCACTGGATACACCGACGCACCGAGAAGGGAAAATGCCGTCAATGTGGAAAGTCACTGCAAGCAAAATTATCATTTAGTTCAAAAGAGATTGTTGCTTTATCTTGTGCCTGGTGTAAATCGTCATATCACAATAAGGAGGCGTGCTTCAATCCGCAGCGCATCGGCGAGGAATGCTCGCTTGGCGCCCACTCGCGCATCATTGTGCCGCCGTCGTGGATCGTGAAATTGCCGCGGAGAGGAAGCTTCAAGTCGTCGCTGAGGAAGACGCCGAAAAAGAAGCCGGCCGGCAAGAAAAAGTCAAAGGAGAAGGAACTGCGAACGTTTGTGATAAAGCCAATTCCCACGCCCAACATTACGCCCGTGCTGGTCTTCATAAATCCGAAAAGTGGCGGCAATCAGGGCGCAAAACTGCTTCAGAAATTCCAATGGCTCTTGAATCCTCGTCAAGTGTTTGACTTGACGCAGGGCGGACCCAAAATGGGCTTGGAACTGTTCCGCAAGGTGCCAAATTTACGAGTGCTCGCATGTGGCGGCGATGGCACCGTGGGCTGGGTGCTCTCCGTGCTCGATCAAATCAATGTAACGCCACCGCCCGCTGTCGGCGTTCTGCCGCTCGGAACGGGCAACGATCTCGCACGTCATCTCGGATGGGGAGGCGGCTACACGGACGAGCCCATCGGCAAAATTCTCTCGAACATTGCAAATTCTGATACGGTTCTGTTGGACCGCTGGAATCTCAAAGTGACGCCCAACGAAAATGCCTCGGACTCCTCCGACGGCAAGGACACGCTGCCACTGAGCGTAGTCAACAACTATTTCTCGCTAGGCGTCGATGCTCACATTGCTCTCGAGTTCCACGAAGCCAGAGAGGCTCATCCGGAAAAGTTCAATTCACGATTGAGAAATAAAATGTTTTATGGACAGGCAGGCGGAAAGGATCTGCTCAAGCGCAAGTGGAAGAATCTCGCCGAGCTGGTAACGCTGGAGTGCGATGGCAAGGACATCACGCCAAAGCTCAAGGAGTTGCGTGTCCATGCGATAGTGTTCCTCAACATTGCGAGCTACGGCGGCGGCACGCATCCGTGGAACAAGTCGGGCGGGCAGTTCGAGCCGTGCACGGATGATGGATTAATTGAAGTTGTCGGTCTTACAACATATCAGCTGCCGCTTCTTCAAGCCGGCGGCCATGGAACGTGTATAACGCAGTGTCGCTCCGCGAAAATCGTAACGTCGAAAACAATCCCGATGCAGGTCGATGGCGAGGCGTGCAAAGTGAAGCCATCAATCATCGAATTGTCTCTGCTTAATAAGGCTGTGATGTTGGCGAAGAAGAAGCCAGGACGAACGAACGTTCCGCAAGCGACACTCGAGCCGATGAGCATCAGCATTTGCCGCATCAAAATGTCCGACTATGAACAACACCATTACGATAAGGAGTCGCTGAAGCAGAGCGCCGCGCCGCTCGGCTCAATCGAAGTCAATCCCACATCCGATCTCGAGGCCGTACGTGTTCTGATAAATAAAATGTCCGAGGAGTGCAGCGACGGTCCCAAGCTGACGGCCGACTGGTGCTTCATTGACTCCTGCACAGCCGAGCGATGCTTCCGCGTTGATAGAGCACAGGAGAATTTACACTATGTCACTGACATCGCGACCGACGTGATTTATGTGCTGGACCAGGAGTGTCCTACACTGCCGCAAACGCCCGAAACCGAGAGCCCCGCGAATCTCGTTAATCCCATCATCTCGAGCATGGAGTCGAGCGACAAGGACTCGCACGACGGAACGCCAATGACGCCCAGCAAGAAGTTCTTCAACCGATCTCTCAGCTCCGGACCGAATTCGGGCGGAACCTCGTCCTCGCGAAAGAGCTCGCAGGGATCGCAGGGCTCGAACGGCAGCGCGCGCAGTTCGCTGAATGCGTCGAAAGAGGACATTGAGAATGCCGGCAACTGCGAGTCGGCCAACTATAAAGCTACACTGCTTGAAAAGACAACTGATGCTGTGATAAAAGCTGCTAAAAATGGAGATCTCGCAATGCTTAAGGAACTTCATCAGCAAGGCTATTCACTGCTGTCGATAGACACGATGGGCAACACGGCGCTCCATCACGCAAGCCGTTACGGGCACAAGGACATCGTGAGGTTCTTGATTGCATACGCGCCCGACTCGATTGTCAATATGATTGATAACGAGAAGGGCCAAACGGCGCTCCACAAGGCGGCCGCAATGAAGCGACGGAGCATCAGCTACATGCTCGTGGCCGCCGGGTCGAATCTACTCATTCAAGACAACGCTGGGAAAACACCAAAAATACTCGCCCTCGAGGCCGACGATCACGATCTGGCAGCTTATCTCGAAAGTCAGGAGCAATTCCACTGCGCGGTT
Protein: 1278 (aa)
MKTQSSLEVPKQVRSASFDEIKLESQRAAQFLLTNQSSTDSQSTLLTVPNSQRSRSFDSAGIEPSDVNASFLDIPRQRFRRKSSAKAPVCIHCQYVEEQRKRGSTAGFYFDAQEFRSLTYSNSSSDESSTSESEDTTTDEPPDGDADDDDIDVDYYFQNQTTLLLPSPCSITFTLSPTNCDYPAFPLPGLVPPSISSPPAMPSTPPVFPTSPTIELTHDVDEIEVPGPRQRRRSISRQEAIFVEPTGSSLENVSNSSDVEQATVTASAPQPSSTPPLTTKESDESERRHSDIPKASEPFVRDIFLTVPDLKRDRAASVDSCFTKVTSAAKTEEVQPPEGDLNLLTVPNSGAVRSRSVDIVLPTEQQARYKALALAGPASNIYNKGKPGDNSGTRQIRNTPDWTENAVSGDHLWVPTSVSGDCCYIGDNDCTKHGPRMKCSACKIIAHANCISVLMERSQLACKPTFRDVGVRQYREQTRTHHHWIHRRTEKGKCRQCGKSLQAKLSFSSKEIVALSCAWCKSSYHNKEACFNPQRIGEECSLGAHSRIIVPPSWIVKLPRRGSFKSSLRKTPKKKPAGKKKSKEKELRTFVIKPIPTPNITPVLVFINPKSGGNQGAKLLQKFQWLLNPRQVFDLTQGGPKMGLELFRKVPNLRVLACGGDGTVGWVLSVLDQINVTPPPAVGVLPLGTGNDLARHLGWGGGYTDEPIGKILSNIANSDTVLLDRWNLKVTPNENASDSSDGKDTLPLSVVNNYFSLGVDAHIALEFHEAREAHPEKFNSRLRNKMFYGQAGGKDLLKRKWKNLAELVTLECDGKDITPKLKELRVHAIVFLNIASYGGGTHPWNKSGGQFEPCTDDGLIEVVGLTTYQLPLLQAGGHGTCITQCRSAKIVTSKTIPMQVDGEACKVKPSIIELSLLNKAVMLAKKKPGRTNVPQATLEPMSISICRIKMSDYEQHHYDKESLKQSAAPLGSIEVNPTSDLEAVRVLINKMSEECSDGPKLTADWCFIDSCTAERCFRVDRAQENLHYVTDIATDVIYVLDQECPTLPQTPETESPANLVNPIISSMESSDKDSHDGTPMTPSKKFFNRSLSSGPNSGGTSSSRKSSQGSQGSNGSARSSLNASKEDIENAGNCESANYKATLLEKTTDAVIKAAKNGDLAMLKELHQQGYSLLSIDTMGNTALHHASRYGHKDIVRFLIAYAPDSIVNMIDNEKGQTALHKAAAMKRRSISYMLVAAGSNLLIQDNAGKTPKILALEADDHDLAAYLESQEQFHCAV
| Type | Start | End | Length |
| CDS |
13103 |
13138 |
36 |
| CDS |
13220 |
14337 |
1118 |
| CDS |
19582 |
19720 |
139 |
| CDS |
20085 |
20288 |
204 |
| CDS |
24827 |
24956 |
130 |
| CDS |
25013 |
25313 |
301 |
| CDS |
25652 |
25826 |
175 |
| CDS |
27594 |
27762 |
169 |
| CDS |
27859 |
27900 |
42 |
| CDS |
28107 |
28166 |
60 |
| CDS |
28616 |
28851 |
236 |
| CDS |
28938 |
29128 |
191 |
| CDS |
29218 |
29444 |
227 |
| CDS |
29893 |
30286 |
394 |
| CDS |
32523 |
32586 |
64 |
| CDS |
32687 |
33008 |
322 |
| CDS |
33368 |
33393 |
26 |
| intron |
13139 |
13219 |
81 |
| intron |
14338 |
19581 |
5244 |
| intron |
19721 |
20084 |
364 |
| intron |
20289 |
24826 |
4538 |
| intron |
24957 |
25012 |
56 |
| intron |
25314 |
25651 |
338 |
| intron |
25827 |
27593 |
1767 |
| intron |
27763 |
27858 |
96 |
| intron |
27901 |
28106 |
206 |
| intron |
28167 |
28615 |
449 |
| intron |
28852 |
28937 |
86 |
| intron |
29129 |
29217 |
89 |
| intron |
29445 |
29892 |
448 |
| intron |
30287 |
32522 |
2236 |
| intron |
32587 |
32686 |
100 |
| intron |
33009 |
33367 |
359 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_310575 |
AGAP000519-PA [Anopheles gambiae str. PEST] gb|EAA06452.5| AGAP000519-PA [Anopheles gambiae str. PEST] |
0.0 |
| InterPro |
IPR002219 |
Protein kinase C-like, phorbol ester/diacylglycerol binding |
|
| InterPro |
IPR001206 |
Diacylglycerol kinase, catalytic domain |
|
| InterPro |
IPR000756 |
Diacylglycerol kinase, accessory domain |
|
| InterPro |
IPR020683 |
Ankyrin repeat-containing domain |
|
| InterPro |
IPR002110 |
Ankyrin repeat |
|
| Gene Ontology(BP) |
GO:0007205 |
activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway |
|
| Gene Ontology(BP) |
GO:0035556 |
intracellular signal transduction |
|
| Gene Ontology(MF) |
GO:0004143 |
diacylglycerol kinase activity |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Pfam |
PF12796.2 |
Ankyrin repeats (3 copies) |
1.3e-15 |
| Pfam |
PF13857.1 |
Ankyrin repeats (many copies) |
5.2e-12 |
| Pfam |
PF13606.1 |
Ankyrin repeat |
3.7e-08 |
| Pfam |
PF00781.19 |
Diacylglycerol kinase catalytic domain |
9.8e-34 |
| Pfam |
PF00609.14 |
Diacylglycerol kinase accessory domain |
1.5e-46 |
| Pfam |
PF00130.17 |
Phorbol esters/diacylglycerol binding domain (C1 domain) |
3.3e-11 |
| Pfam |
PF13637.1 |
Ankyrin repeats (many copies) |
3.1e-17 |
| Pfam |
PF11815.3 |
Domain of unknown function (DUF3336) |
0.13 |
| Pfam |
PF00023.25 |
Ankyrin repeat |
1.6e-13 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000395684 |
| H. sapiens |
ENSP00000320340 |
| A. aegypti |
AAEL013849 |
| H. sapiens |
ENSP00000399131 |
| D. plexippus |
DPOGS207466PA |
| H. sapiens |
ENSP00000434719 |
| H. sapiens |
ENSP00000436273 |
| H. sapiens |
ENSP00000436291 |
| N. vitripennis |
NV14336-PA |
| S. invicta |
SI2.2.0_11956 |
| H. sapiens |
ENSP00000396078 |
| H. sapiens |
ENSP00000392161 |
| T. castaneum |
TC000797 |
| D. melanogaster |
FBgn0261549 |
| H. sapiens |
ENSP00000343065 |
| H. sapiens |
ENSP00000391021 |
| A. gambiae |
AGAP000519 |
| C. quinquefasciatus |
CPIJ018790 |
| H. sapiens |
ENSP00000288490 |
| M. musculus |
ENSMUSG00000040479 |
| H. sapiens |
ENSP00000412178 |
| P. vanderplanki |
Pv.01286 |
| A. mellifera |
GB11009-PA |
| M. musculus |
ENSMUSG00000038665 |
| P. humanus |
PHUM178430-PA |
| A. aegypti |
AAEL013847 |
| H. sapiens |
ENSP00000378941 |
| H. melpomene |
HMEL016686-PA |
| B. mori |
BGIBMGA001172-TA |