MidgeBase gene description page [Pn.08610]
Outline
| Gene ID | Pn.08610 |
| Type | Protein coding gene |
| Scaffold | PnScaf8304 |
| Start | 2252 |
| End | 4453 |
| Direction | + |
Sequence
Transcript: 2052 (bp)
ATGGCTTCTTCGCAAAGGGAAGCTCTTGTGATTTTGATGGATATTGGACGAGCATCATGGAGCAATGATTATGAAACAGGAAGCATTTCATATTTCGATCGCGCTAAGAGCTGCATCAAGAAAATTATAATGAGAAAGATTCTCTGCAATCCAGATGATGAAATTGGAATCGTACTTTTTGGATGTAATCACACGAAAAATGATCTCAACACATCGCTTTCTGGTTTCGACAATGTCTATGAGATGAATTCAATGCAAAACGGAACATGGGAACTCGTAAGAAAGATCGAAACTTTAGAAAAAGGAGACGTCGAAGGAAATTGGGTTGAAGGAATGCTGGTGGCCATCAATTACATGAAAAATGAGACTGAAGCAAAAAAAATCGGCAGCCATCGCATAATTTTGTTCACGAACTTTTTAACTCATGTTGAAGAGGATGATGATCTCAACGTCATAATCGACCAAATTATGCAGAACGATATCCAATTGATTGCCGCCTCAAGCAAACTCGAAAGCAGTTCCCAGCCGAAAGTTTTAAGCAAAAGTGAAGAGTTGTTTCAAGTAATTGGGGAAAAAACGGAAAATGTGATTCCGTGCAGCATGGACACTATCGAGTCTGGATTGACTTACTACACTAAAGGACATGGTCGATCAGTACCCTGGAATTGTGCCTTGACCATAGGCGAAATATCCATAAATACGAGCGCTTTCGTGTATGTTCAACACGAAAAAATGTTTCCCGGTTTCAAAACTGAGTGCATTGAGCACAACACAGCTACAAAACTAACCACCGAGTATTTCCAGAACAACAAACAGATCGACAAGCCAAGCGCTGATGATATTGTAAAGGCGTACATGTACGGCTCTAAATTGGTCGCAATCGATGACCCAGATATTGCACTCGACGGCGGCAGCAAGTGCCTAGCCTGCTTGGCCTTCTGTAAACGCTCTCAGATTTTGCCAGACTACTTAATTGGAAAGGGCTGTCACATTGTAGTACCTCAGAAAGGATTTCAAAAGAGCGCCAATATTTTCGAAGCTCTCGTTGAAGCTATGAATAAGAGAAACTACGCTATGGTGGCGAGAAAGGTTTATCGTGAAGGAGCAAAGCCACACATTGTTGCCCTCATTCCAAAGATTGAAGACGAATCATTCTACCTTCTGATGTATGAGATAGCATTTGACGACGATATTGAGTATATTTATTTTCCGAAACTCGAAAGAAAAGACACACAGCCAAGCGGCGAGCAAATGGAAGCGATGAAAAAGTTGGTCGAACTGATGGAACTCACAAGTGAAAGCGACGAAGTGTTTCACCAAGATGCACTTTTCAATCCTGCATTTCAAAACATGTGTCAGTCGATAGCTTTCCGAGTACTCAACCCAGATCAACCGCTCCCGCCGGTGAATGAGGATGTTTTGAAGCTAATACAAACTCCCGACGGGATCAAAGCACGCATCAACAGCTTCATGGAAGAGTTTGATGCGGTCTTTCCCAAGGAAATCGTGGAACGTAAAGCAAAAAAGCCGCTGGGTCAAACACAAGATGTAGAAGGAGTGATTTCTTTGGACGATTCGGACATTTACGAGGAGCTGGAGGCAGATCAGCGAGCAACTGTTGCTGTGGGAAGTGTGACGCCTGCTGAGGATTTCTATTATCTCATCAAAAAGGGAGCTCTTCTCTTCAGTACACTGTGCGAGCAAATCGAAGGCATTATTTATGAGATGATCTTTAAATCGTGCGTCGATATGGAAGAAAAAGTCAAGGAGACTATCATGGCATATCGTGAGGCCGCAAAAATTCATGGTCCTTTCAACTACAACGAATGGATCAAGAACTTGAAGGCATCAATGATTAAGCGCGACAAAATTGATTTGTGGAACAAAATTGTTGTACGCGAAGGATTCGGTCTTATTTCGCAAACTGAGTCACTAATATCGACAGTCACCATCGATGATCAACTGACCTTTTATGATACTGTTTCGAAGGAGTCATCGCGAAATTTAACATCAACTCCAATGGATGAAGACGACAATCTAGAGGCATTGCTA
Protein: 684 (aa)
MASSQREALVILMDIGRASWSNDYETGSISYFDRAKSCIKKIIMRKILCNPDDEIGIVLFGCNHTKNDLNTSLSGFDNVYEMNSMQNGTWELVRKIETLEKGDVEGNWVEGMLVAINYMKNETEAKKIGSHRIILFTNFLTHVEEDDDLNVIIDQIMQNDIQLIAASSKLESSSQPKVLSKSEELFQVIGEKTENVIPCSMDTIESGLTYYTKGHGRSVPWNCALTIGEISINTSAFVYVQHEKMFPGFKTECIEHNTATKLTTEYFQNNKQIDKPSADDIVKAYMYGSKLVAIDDPDIALDGGSKCLACLAFCKRSQILPDYLIGKGCHIVVPQKGFQKSANIFEALVEAMNKRNYAMVARKVYREGAKPHIVALIPKIEDESFYLLMYEIAFDDDIEYIYFPKLERKDTQPSGEQMEAMKKLVELMELTSESDEVFHQDALFNPAFQNMCQSIAFRVLNPDQPLPPVNEDVLKLIQTPDGIKARINSFMEEFDAVFPKEIVERKAKKPLGQTQDVEGVISLDDSDIYEELEADQRATVAVGSVTPAEDFYYLIKKGALLFSTLCEQIEGIIYEMIFKSCVDMEEKVKETIMAYREAAKIHGPFNYNEWIKNLKASMIKRDKIDLWNKIVVREGFGLISQTESLISTVTIDDQLTFYDTVSKESSRNLTSTPMDEDDNLEALL
| Type | Start | End | Length |
| CDS |
2252 |
2269 |
18 |
| CDS |
2349 |
2701 |
353 |
| CDS |
2770 |
4450 |
1681 |
| intron |
2270 |
2348 |
79 |
| intron |
2702 |
2769 |
68 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001861497 |
ku P80 DNA helicase [Culex quinquefasciatus] gb|EDS35682.1| ku P80 DNA helicase [Culex quinquefasciatus] |
1e-115 |
| InterPro |
IPR005161 |
Ku70/Ku80, N-terminal alpha/beta |
|
| InterPro |
IPR006164 |
DNA helicase, ATP-dependent, Ku type |
|
| InterPro |
IPR016194 |
Spen Paralogue and Orthologue SPOC, C-terminal-like |
|
| InterPro |
IPR005160 |
Ku70/Ku80 C-terminal arm |
|
| InterPro |
IPR014893 |
Ku, C-terminal |
|
| Gene Ontology(BP) |
GO:0006303 |
double-strand break repair via nonhomologous end joining |
|
| Gene Ontology(MF) |
GO:0016817 |
hydrolase activity, acting on acid anhydrides |
|
| Gene Ontology(MF) |
GO:0003677 |
DNA binding |
|
| Gene Ontology(MF) |
GO:0004003 |
ATP-dependent DNA helicase activity |
|
| Pfam |
PF02735.11 |
Ku70/Ku80 beta-barrel domain |
1.1e-27 |
| Pfam |
PF03731.10 |
Ku70/Ku80 N-terminal alpha/beta domain |
2.2e-27 |
| Pfam |
PF08785.6 |
Ku C terminal domain like |
1e-21 |
| Pfam |
PF03730.9 |
Ku70/Ku80 C-terminal arm |
0.00019 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| A. aegypti |
AAEL003684 |
| S. invicta |
SI2.2.0_15786 |
| A. mellifera |
GB12351-PA |
| P. vanderplanki |
Pv.10272 |
| H. sapiens |
ENSP00000375977 |
| P. humanus |
PHUM529370-PA |
| N. vitripennis |
NV30285-PA |
| H. sapiens |
ENSP00000375978 |
| T. castaneum |
TC013478 |
| D. melanogaster |
FBgn0041627 |
| C. quinquefasciatus |
CPIJ801820 |
| H. melpomene |
HMEL008253-PA |
| D. plexippus |
DPOGS204693PA |
| A. gambiae |
AGAP009910 |
| M. musculus |
ENSMUSG00000026187 |