MidgeBase gene description page [Pn.08540]
Outline
| Gene ID | Pn.08540 |
| Type | Protein coding gene |
| Scaffold | PnScaf8192 |
| Start | 54138 |
| End | 58333 |
| Direction | + |
Sequence
Transcript: 3963 (bp)
ATGCAGGCAGATTTGGTTTTCTATGTGAATGGAAAGAAGATAAGCGAAAATAAGCCCGACCCTGAGGTAACTTTATTGCGTTATTTACGCGAAAAACTGCGATTGAGTGGCACGAAGTTGGGATGCGCGGAGGGCGGCTGCGGTGCATGCACCGTGATGGTCTCCAGCTACGACCGCACCACAGCAACTGTCAAGCATTTCTCGGCAAACGCCTGCTTGATGCCGGTGTGTGCACTGCACGGTCTCGCCGTGACAACAGTCGAAGGCATTGGCAGCACTCGAACCCGACTGCATCCCGTTCAGGAGAGAATCGCGAAGGCACATGGCTCGCAATGCGGCTTCTGCACGCCCGGCATTGTGATGTCGATGTACGCGCTGCTCCGAAACTCATCTCAGCCGTCGATGAAGCAGCTGGAGGAGGCGATGCAGGGCAACTTGTGCCGCTGCACCGGCTACCGGCCGATCATCGAGGGCTACCGAACTTTCACGAAGGAGTACGACTGCGGCATGGGCGACAGTTGCTGCAAGATGGTGGGCGCCAAATGCGGGCAACTTGTCGACAGCAAGCTCTTTGACACCAACGACTTTGTGCCCTACGATCCGTCGCAGGAGCCGATCTTTCCGCCGGATCTCAAGCTTACCGACGAGTACGAAAGGCAGAGCGTGGAGTTTCGCAACGATCGCGGCGTGGTTTGGCTGAGACCGACACAGCTGAGCGAGCTGCTGAGATTCAAGAAGCAGCATGGAGCGGCAGCGAAAATTGTCGTCGGCAACACGGAGCTTGGCGTCGAGGTGAAGTTCAAGCACTTTGACCACAAGTTCTACGCGCATCCGACGCAGATCCGAGAGATGAACGACCTGGAGGCGAACGACGATGGAGTCAGAGTCGGAGCTGCTGTCACGTTGACCGACCTTCAGAGTTTCCTGCAAAAGCAAATCGACGAGTGCAAGCACGAAGCTGGTTTGTACCGTTCGATCGTCGACATGCTTTTCTGGTTCGGCAATCTTCAAGTTCGCAATGTGGCGACGCTTGGCGGCAATCTCATGGCGTGCTCGCCCATTTCCGACCTGAATCCGCTTCTTCTCGCCGCTGGTGCTGAGGTTGAGGTCGAGAGCGTCGATGGCGGAAGAAGAAGAATCAAGATGGACGAGAATTTCTTCAAAGGCTACCGTCAGTGTGCTGTTGAAGACTCTGAAGTTCTTCTCTCCGTGTTGATCCCGAAAACCTGCAAAAATCAGCACTTTGCCGCTTACAAGCAGGCGAAACGTCGCGAAGACGATATGTCCTACGTCACGGCAGCCTTCAACGTGAAATTCATCGAAGGAACGAGCATTGTCGAGGACGCAAAAGTGGCGTTCGGTGGAATGTCGAGCACGACGCTAATGGCTGTAAAAACAGGCGAAATCATGAAAGGAAAGGCGTGGAATCGCGAGCTCATTGAGATCGTAAATCAGAGCCTCATCGACGAAATTCCGCTGCCAGCTGATGCACCGGGCGGTGCCGTTCTTTACCGCCGTTCGCTCACTCTGAGCCTCTTCTTCAGAGCATTCCTCAGCATCGGCCAGAAGCTCGAAGCGCAGCTGAATCTGAGCATTCTGGAGGAGCGAGAGAGAAGCGGCAGCGAAGGCTTTCAGGCGCTCACGCCGAAGAGTTCACAGCTCTTTGAGAAAGTTTCCTTCGATCAACCGCCGACCGATCCGATTCATCGCCCGATCGTGCACGCGTCAGCCTTCAAGCATGCCACTGGCGAAGCTATCTACTGCGACGACCTTCCCGAGCATACGAATGAGCTGTATCTCGCGCTGGTGCTGAGCTCGAGGGCTCACGCGAAAGTCGTTTCGATCGACGAAAGCGAGGCGCTCAAGCAGCCCGGCGTGCACGCCTTCTTCTCGGCCAAGGACGTCGACCAAAGTCTTTTTGGTGCCAGCCTGGCGTTTGGGGAGGAGCTGATCTTCGCGAAAGACACAGTGACGAGCGAAGGTCAAATTATCGGCGCCATTGCAGCGGACGACCAGCTGATTGCGCGACGAGCCGCTCGAATGGTGAAGGTCGAGTACGAAAACCTGTCGCCGGTCATTGTGACGATTGAGGACGCGCTCGAGCACAACTCCTTCTTCCCCGAGTACCCGATGGCCTTCAAAAATGGCGACATCGAGGAGGTTTTCGAGAGAGCCGATCGCGTCGTCGAGGGAGAAGTCCGAACGGGCGGCCAGGAGCACTTTTACCTCGAGACGCACTCAAATCTGGCGATTCCTCGAGACAGCGACGAAATCGAACTCTTCTCGTCGACTCAGCAGCCGTCCGAGTTGCAGCGTCACGTCGCAAACTTTCTGCGAATTCCGCAGCACAAAGTCGTTTGTCGTGCGAAGAGAGTCGGCGGCGGCTTTGGCGGAAAGGAGACGCGCGGTTTTCTTTCAGCCCTGCCTGTCGCCCTCGCTGCTTACAATCTCAAGCGACCAATCCGAATGGTGCTGGATCGCGACGAGGACATGATGATGACGGGCGGCCGAAACCCGATTTTGTTCAAGTACAAGGTGGCGTGCGACCACGAGGGAAAACTGCTCGGAATGTTCATCAGAGCTTTCCTAAACGCGGGCTACTCCCTCGACTACTCGCGCTATGTCATCGAGAGTGCCTACGCGAGCATCGTCAACGCTTACAACTTCAGTGTGGTTCACTTCGAGGCAAATGTTTTGAGAACAAACACACGCTCGAACACGGCTTTTCGTGGATTTGGTGCGCCGCAAGGCATGCTTGCCGCCGAGGCAATCATCCGCGATGTGGCGCGAGTCACTGGCAAAGATTATACCGAAATTATGGTGCTCAACATGTGCAAGACCGGCGACATCATGCACAACGGTCAGCTCCTCGAAAACTGCAACGTCTCGCGTTGCTACCAAGAAGTTCTAGCGAGCTCTGACTTTGAGAAGCGGAGATCGGCCGTCGCGAAATTCAATGCCGAAAATCGATGGAAGAAACGCGGAATCAGCGTAACCAACAACATGTTTGGCGTCGGCTTTCCGCCTGCCTTCATGAACCAGGGCGGCGCGCTCGTTCACGTCTACCTCGACGGAACGGTCCTGGTTTCGCATGGCGGCGTCGAAATGGGCCAGGGACTGCACACGAAGATGCTGCAGATCGCGTCTCGTGTCCTGGACATTCCAATATACAAGATTCACATTCAAGAGACGGCCACCGACAAGGTGCCGAACGCCATTTCCACAGCTGCGTCCGTGAGCTCTGACTTGTATGGTGGCGCCGTCATGAGTGCATGTCAAACCATTTACGATCGCTTGACTGTGTACCGTCGAGCAGCACCGAAGGCAGACTGGTGCGACTGGGTGCGGACGGCCTACTTGGATCGGGTGTCGCTCTCAGCGACCGGCTTCTTCGCCACGCCCGACATCGGCATCGAGATCAACAAGCCGAAGAACTACTTCACGCACGGCGCAGCAGTTTCGGAGGTCGAAATCGACTGCCTCACTGGCGATCACCAAGTGCTGAGAACGGACATCGTCATAGACGTCGGCAGCTCCTTGAATCCTGCCATCGACATCGGACAGATTGAGGGCGCCTTCATGCAGGGCTACGGCCTGTTTGTCATTGAAGAGCTGGTCTACTCGCCGACCGGTGCCTTGCTCTCGAAGGGCCCGGGCATGTACAAGCTGCCCGGCTTCGCCAGCATTCCCGCCGAGTTCAATGTGTCGCTTCTCACTGGAGCTCCGAATCCGAGGGCGGTTTATTCGTCACGTGCAGTTGGCGAGCCGCCACTGTTTCTCGCGTCTTCAGTTTTTTTCGCCATCAAGGAAGCCATCGGTGCAGCAAGGCAGGAGGAGGGACTTGGCGACCATTTTTACTTGCAATCGCCAGCCACATCGGAGAGAATCAGAATGGCGTGTCAGGATGGAATTACAAAGAAGTTCAGCGATGAAAAGACCACAAAGCCGTGGAGCATACATCTT
Protein: 1321 (aa)
MQADLVFYVNGKKISENKPDPEVTLLRYLREKLRLSGTKLGCAEGGCGACTVMVSSYDRTTATVKHFSANACLMPVCALHGLAVTTVEGIGSTRTRLHPVQERIAKAHGSQCGFCTPGIVMSMYALLRNSSQPSMKQLEEAMQGNLCRCTGYRPIIEGYRTFTKEYDCGMGDSCCKMVGAKCGQLVDSKLFDTNDFVPYDPSQEPIFPPDLKLTDEYERQSVEFRNDRGVVWLRPTQLSELLRFKKQHGAAAKIVVGNTELGVEVKFKHFDHKFYAHPTQIREMNDLEANDDGVRVGAAVTLTDLQSFLQKQIDECKHEAGLYRSIVDMLFWFGNLQVRNVATLGGNLMACSPISDLNPLLLAAGAEVEVESVDGGRRRIKMDENFFKGYRQCAVEDSEVLLSVLIPKTCKNQHFAAYKQAKRREDDMSYVTAAFNVKFIEGTSIVEDAKVAFGGMSSTTLMAVKTGEIMKGKAWNRELIEIVNQSLIDEIPLPADAPGGAVLYRRSLTLSLFFRAFLSIGQKLEAQLNLSILEERERSGSEGFQALTPKSSQLFEKVSFDQPPTDPIHRPIVHASAFKHATGEAIYCDDLPEHTNELYLALVLSSRAHAKVVSIDESEALKQPGVHAFFSAKDVDQSLFGASLAFGEELIFAKDTVTSEGQIIGAIAADDQLIARRAARMVKVEYENLSPVIVTIEDALEHNSFFPEYPMAFKNGDIEEVFERADRVVEGEVRTGGQEHFYLETHSNLAIPRDSDEIELFSSTQQPSELQRHVANFLRIPQHKVVCRAKRVGGGFGGKETRGFLSALPVALAAYNLKRPIRMVLDRDEDMMMTGGRNPILFKYKVACDHEGKLLGMFIRAFLNAGYSLDYSRYVIESAYASIVNAYNFSVVHFEANVLRTNTRSNTAFRGFGAPQGMLAAEAIIRDVARVTGKDYTEIMVLNMCKTGDIMHNGQLLENCNVSRCYQEVLASSDFEKRRSAVAKFNAENRWKKRGISVTNNMFGVGFPPAFMNQGGALVHVYLDGTVLVSHGGVEMGQGLHTKMLQIASRVLDIPIYKIHIQETATDKVPNAISTAASVSSDLYGGAVMSACQTIYDRLTVYRRAAPKADWCDWVRTAYLDRVSLSATGFFATPDIGIEINKPKNYFTHGAAVSEVEIDCLTGDHQVLRTDIVIDVGSSLNPAIDIGQIEGAFMQGYGLFVIEELVYSPTGALLSKGPGMYKLPGFASIPAEFNVSLLTGAPNPRAVYSSRAVGEPPLFLASSVFFAIKEAIGAARQEEGLGDHFYLQSPATSERIRMACQDGITKKFSDEKTTKPWSIHL
| Type | Start | End | Length |
| CDS |
54138 |
54176 |
39 |
| CDS |
54268 |
56920 |
2653 |
| CDS |
56987 |
58215 |
1229 |
| CDS |
58289 |
58330 |
42 |
| intron |
54177 |
54267 |
91 |
| intron |
56921 |
56986 |
66 |
| intron |
58216 |
58288 |
73 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001662131 |
aldehyde oxidase [Aedes aegypti] gb|EAT46105.1| aldehyde oxidase [Aedes aegypti] |
0.0 |
| InterPro |
IPR016208 |
Aldehyde oxidase/xanthine dehydrogenase |
|
| InterPro |
IPR001041 |
2Fe-2S ferredoxin-type domain |
|
| InterPro |
IPR002346 |
Molybdopterin dehydrogenase, FAD-binding |
|
| InterPro |
IPR014307 |
Xanthine dehydrogenase, small subunit |
|
| InterPro |
IPR012675 |
Beta-grasp domain |
|
| InterPro |
IPR016167 |
FAD-binding, type 2, subdomain 1 |
|
| InterPro |
IPR002888 |
[2Fe-2S]-binding |
|
| InterPro |
IPR016166 |
FAD-binding, type 2 |
|
| InterPro |
IPR005107 |
CO dehydrogenase flavoprotein, C-terminal |
|
| InterPro |
IPR006058 |
2Fe-2S ferredoxin, iron-sulphur binding site |
|
| InterPro |
IPR016169 |
CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 |
|
| InterPro |
IPR000674 |
Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead |
|
| InterPro |
IPR008274 |
Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding |
|
| Gene Ontology(BP) |
GO:0055114 |
oxidation-reduction process |
|
| Gene Ontology(MF) |
GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors |
|
| Gene Ontology(MF) |
GO:0009055 |
electron carrier activity |
|
| Gene Ontology(MF) |
GO:0008762 |
UDP-N-acetylmuramate dehydrogenase activity |
|
| Gene Ontology(MF) |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
|
| Gene Ontology(MF) |
GO:0004855 |
xanthine oxidase activity |
|
| Gene Ontology(MF) |
GO:0005506 |
iron ion binding |
|
| Gene Ontology(MF) |
GO:0050660 |
flavin adenine dinucleotide binding |
|
| Gene Ontology(MF) |
GO:0004854 |
xanthine dehydrogenase activity |
|
| Gene Ontology(MF) |
GO:0003824 |
catalytic activity |
|
| Gene Ontology(MF) |
GO:0051536 |
iron-sulfur cluster binding |
|
| Gene Ontology(MF) |
GO:0046872 |
metal ion binding |
|
| Gene Ontology(MF) |
GO:0016491 |
oxidoreductase activity |
|
| Pfam |
PF00941.16 |
FAD binding domain in molybdopterin dehydrogenase |
1.1e-47 |
| Pfam |
PF03450.12 |
CO dehydrogenase flavoprotein C-terminal domain |
3.1e-28 |
| Pfam |
PF01315.17 |
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain |
3.1e-34 |
| Pfam |
PF00111.22 |
2Fe-2S iron-sulfur cluster binding domain |
1.4e-08 |
| Pfam |
PF01799.15 |
[2Fe-2S] binding domain |
3e-29 |
| Pfam |
PF02738.13 |
Molybdopterin-binding domain of aldehyde dehydrogenase |
5.1e-187 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
| Gene ID |
| Pn.00988 |
| Pn.13874 |
| Pn.14146 |
| Pn.14305 |
| Pn.16491 |
| Pn.08772 |
Orthologous genes
| Species |
Gene ID |
| T. castaneum |
TC001978 |
| D. plexippus |
DPOGS205480PA |
| H. melpomene |
HMEL011575-PA |
| D. plexippus |
DPOGS204718PA |
| A. aegypti |
AAEL010380 |
| A. aegypti |
AAEL010370 |
| H. sapiens |
ENSP00000368727 |
| A. gambiae |
AGAP006221 |
| T. castaneum |
TC012131 |
| D. melanogaster |
FBgn0003308 |
| D. plexippus |
DPOGS208006PA |
| A. mellifera |
GB17045-PA |
| B. mori |
BGIBMGA008244-TA |
| A. aegypti |
AAEL002683 |
| P. vanderplanki |
Pv.05209 |
| P. vanderplanki |
Pv.00084 |
| N. vitripennis |
NV11547-PA |
| B. mori |
BGIBMGA008445-TA |
| A. aegypti |
AAEL010367 |
| D. plexippus |
DPOGS205813PA |
| A. gambiae |
AGAP006220 |
| D. plexippus |
DPOGS208007PA |
| D. plexippus |
DPOGS204714PA |
| M. musculus |
ENSMUSG00000024066 |
| N. vitripennis |
NV12674-PA |
| T. castaneum |
TC013628 |
| D. melanogaster |
FBgn0038347 |
| P. vanderplanki |
Pv.14266 |
| D. melanogaster |
FBgn0038349 |
| C. quinquefasciatus |
CPIJ013922 |
| P. vanderplanki |
Pv.15581 |
| A. aegypti |
AAEL010384 |
| D. melanogaster |
FBgn0038348 |
| C. quinquefasciatus |
CPIJ013934 |
| A. gambiae |
AGAP005638 |
| C. quinquefasciatus |
CPIJ017836 |
| D. plexippus |
DPOGS205814PA |
| H. sapiens |
ENSP00000363832 |
| N. vitripennis |
NV50063-PA |
| D. plexippus |
DPOGS200223PA |
| A. gambiae |
AGAP005636 |
| A. gambiae |
AGAP005637 |
| M. musculus |
ENSMUSG00000064294 |
| B. mori |
BGIBMGA010377-TA |
| C. quinquefasciatus |
CPIJ004121 |
| T. castaneum |
TC001977 |
| B. mori |
BGIBMGA008268-TA |
| H. melpomene |
HMEL017520-PA |
| C. quinquefasciatus |
CPIJ016888 |
| N. vitripennis |
NV12536-PA |
| N. vitripennis |
NV12673-PA |
| B. mori |
BGIBMGA008439-TA |
| A. aegypti |
AAEL010630 |
| A. mellifera |
GB16018-PA |
| P. humanus |
PHUM299090-PA |
| A. gambiae |
AGAP013758 |
| H. melpomene |
HMEL003020-PA |
| A. gambiae |
AGAP006226 |
| C. quinquefasciatus |
CPIJ802187 |
| N. vitripennis |
NV11546-PA |
| M. musculus |
ENSMUSG00000038242 |
| A. aegypti |
AAEL014493 |
| S. invicta |
SI2.2.0_11360 |
| A. gambiae |
AGAP007918 |
| C. quinquefasciatus |
CPIJ013921 |
| H. melpomene |
HMEL003018-PA |
| D. plexippus |
DPOGS210883PA |
| S. invicta |
SI2.2.0_01859 |
| D. melanogaster |
FBgn0038350 |
| A. aegypti |
AAEL006163 |
| A. aegypti |
AAEL017311 |
| S. invicta |
SI2.2.0_07033 |
| C. quinquefasciatus |
CPIJ013920 |
| M. musculus |
ENSMUSG00000063558 |
| A. aegypti |
AAEL010382 |
| A. aegypti |
AAEL010391 |
| B. mori |
BGIBMGA008421-TA |
| A. gambiae |
AGAP006224 |
| H. melpomene |
HMEL003019-PA |
| P. vanderplanki |
Pv.14267 |
| M. musculus |
ENSMUSG00000079554 |
| H. melpomene |
HMEL003022-PA |
| H. melpomene |
HMEL002194-PA |
| P. vanderplanki |
Pv.00085 |
| B. mori |
BGIBMGA008418-TA |
| A. aegypti |
AAEL006157 |
| C. quinquefasciatus |
CPIJ013919 |
| B. mori |
BGIBMGA008440-TA |
| S. invicta |
SI2.2.0_05661 |
| C. quinquefasciatus |
CPIJ016889 |
| C. quinquefasciatus |
CPIJ017835 |
| H. melpomene |
HMEL017529-PA |
| A. aegypti |
AAEL010372 |
| A. gambiae |
AGAP006225 |
| P. vanderplanki |
Pv.01733 |
| H. melpomene |
HMEL011718-PA |