MidgeBase gene description page [Pn.08419]
Outline
| Gene ID | Pn.08419 |
| Type | Protein coding gene |
| Scaffold | PnScaf8080 |
| Start | 26330 |
| End | 31825 |
| Direction | - |
Sequence
Transcript: 5148 (bp)
ATGAGTAAAAACTTAGATAAACTGAAGCAATTTTTTCGAAGCAACAAGGTTAGTGGTGGGCAAGAGAGGGTTCACGTGCTAACTACGGAGCTAGAAAGGGAGCTGCGAAAAGATAATTCACTCGAAAAAAGATTGAAATTATTAAAAGACTTGAGCGATGTTGTTTCGACAAATAGACTAGAAGAGTTTGCAGTTCAAAAGCTGTGGTCTCTTACAAACGATTTGCTTGAACCGAATAAAGAACCATACGTCAGAGAGGCGACTCTCATGTTTTATACAAAACTGATTCAGGGTCAATACCGAGACTTGGCAATAATGCGAGCCCATTTCTTCAAATTGGTCCAAAACCACAAAATTTCTTCTGATCTTCCTGCATGTCTCCAAATGCTTAAGACTCTAACCGAAAATGGAAGAGATATTCAAAACTTTGAAGAAGAAATCGGATCCTTCATGCTCGGCTGGATGGATCAGATAGTGGAGGCTCAACTGACAGCATCGTATCTTGATTTATTTGTAAATCTCATCAAGTACAACACCGCCTATATTGATCGCGAAGTCATCATTAAGGTCGTCCAACGAGTTTGCAACGACATTTGCTTCAAGTTCCTCGATGATCGTGAAACCTTTCTCCAATGTCTCAACGTAATCGAGACGGTCATCTGCTATAGTGTATTTCCTAACGAAATTTTATCTGTTTGCATCATTGTTCTGTGCCGTGCTGTTAACTTTGAAATGTACGTCGAACCATCATACAAAATCATGAGGAATTTATTGGGCACCCAGTTGGGATATGCGTCACTTCTTATAATGTGCAACATGCTTAAGGAGCACGCATATTATCACGACGCATACGTATTGAGAGGCGGTGTTTTTCATACGAACATGAATCTATGGGGCGGTAACAATAGTTCGCTGCAAAATGGAGTCAAATATAGTTCGGTGGTACTGTCAAGTTACTGTGAAGTTCTAAAATCACGCTCCATAATTGTCACCTATGAAGTTATTTTGAGCTTGCAAACACTTATTGTTAAATGTGGCAGCAATTTAAGTGAACCCTCATGGGATATCATCATAGAAACTATCAATAGAATTCTAGACAATATTGAGTACGAAAATTTACCAGACCATTCGGACATAATGACTCGCTTGCATGCAATGTTCGATAGTCTTGAGACTCTCATCATTCAGCATGAATGCAATGTAAATGTAAATGTTGATAGGGTGTATGCAGTAATCGAGAGAATAAGCAACAAAAGACCGGAGTCTTCAGTCATAAACTTGATAAATCACAAAGCATCAAAGCTCAACACAATGTCCTCGGGATGGGTGAAGAACCTTAATTGCTTCATGGAAAGATTTTATCGCAACGAAAATAGCCAATCGATTCGTCTGGCAACCATTGATCATTTAAAGGAATTTATAAATTTAAATCGTACATGCTATGAGGAAGAAATTTTGGAGAAGGTCGTAATAGTTGTGTTCTCTGACATAGCACAAGAACCAGATGTAAAAATTCGAGTTTCAGTATGCAAACTTTTACTAGAAATTTGCTCCCATTGTGACACAAAGAGATGCATAGAATTACTGGATATTTTGGAAAAGGTCATGAATCACCCATTTGACATTTATTTGTTGAATAGTACAGCTCTAAAAAGCGAACACGACTTCGAAGACTCGATTGTAGTTGTCAATGGAATGATAGACTTATTCTTAGAAAAACTACATCAGCTGCCGACAAGTCATGCAATAAAAATTTATTACATTCTCATCGGTCATTTGGAAACGCACTATCAGCAGCCAAAAGTGTTTGAGCATGCTACTAAAATGCGTTACAGTATAATCAATTGGATGCTGAGAGTTCGTGCCAACTCTTCATTTCAAATAGGATACCCTTCTCCTCGGTTAATAAGCGAAAACATAAAATACAGTCACTATCTCGCTGTCGAAGGAGAATTTCAACATCCTCCACCTCAAACGCCAAACATTCAAGAAATTCAAAATACCGGCGAAGAGAAACAAGAAGGGCCTTTTAATTTCAATACTTTAACGACGCTTTCCATTAAAAGAGGCTGTAAAATAATCGTAAAGTGTCTTGATCAGGAAAAGGACTGGCATACTGTTCAACTGGTGCTTCGAGAACTTCCCAAGATAATGCAAAATAAGACTCTCATACAAGGAAACGACGTCGATATTCTAGCTCGATCTCTGTCAGAGCTTTTTCGCATAAGTTATGGAAAGGAGAAACTCATGGAGCGATTTTCAACATTGAACGAGCAGAAAGATTTTCGATCATTAGTCATGCCGGCTATAGCAAGTCTCATCACATACAATTCATTTCTTAGTCCTTTGACGAAAAAGAAAATCGTCGAGATACTAAAGTCTGAAGTTCGTATGGACGGAAGTTTGAGTATTTGTGTGCAAGCATTTACGATATTACTGATGGAGCGTTGTGATATTTTTGAAAGACAGTTGGCTGACATTGTTTTAGCGATTTCAAAAGTCAGTGATACGATGCTTGTGGCAATACCTATCTTGGAATTCATGTCTACCATAACTCATCTGCCATATTCATTCACAAATCTTAACCAGAAACAATTTTCTTACGTCTTTGCGACGTGCTTGCCCTACACATCTCCTGCTCGTTACGATCACTATGTTGTGTCACTCGCCCATCATATCATTGCCAGTTGGTTCTTGAAATCCCGACTTCAATGGCGCAAACAATATGCCGACTATATTATTGAGGGCATTGCGAAAAATATTGATAAATCGATGCAGGATGCAAAACACTTGCAACGGCAGACGCAAGACGATGCCAATAAAGGATTTCAACTTGTAAACGAAGATTCGGCTCACCGAAAGCGAAGTTCAAGTTTAACGGAGCAATCGAATCGTAGACGAGAAATAAACAATCCGCAAATAATGAAGATGAAGGCTCAAAGAGCTGCTCTGCATACACTGTCACCATCATTTGACATGCACAGCTTTCATATTGAATTGATTGAAACTTGCATAGATTTTATGACGCGTCACACGTATTCATTGTCTCTTGCATTGCCGAGGCGATTACCAAGTGCCAACTACCTCTTGCGTGGAGGCGGTCAGTCAAAGACATGGGTTGTCGGCCATGTAGTAATTACGATTACGACAAATGCTTGCATGGATAATCACGATTGGACAAGCTGCTCGTGTTTTTGTTCAGACTGGGCTGAAATCACCATTCGTCGACCAACCGGAATGCTTTCGTGGATGATGAAATTTCAAAATCAAGTAGGAGCGTTTGCAAATGAATTCTCATTTCACGATCTGAAAGGTCTTTTTACTGATTATGAACTCGATCCTGAAAATCCTAGTGGAGTACTCGTTAAGAAAAAGAATGAAGATTTCAAATCGGATGAGGCAGCCTTACTGATGGAAAAGTTGTCGATAGGAGATGATTTTAACAAAATTCCTTTGCAAGCAACTGCTAGCGATTCCGCGGTTTCGACAATAGTAACTCAGCCCATAAATATTCCCTCTAGTAAGCCTGAGACTGAGCAGAGTGCAGCGGAAGATGATGCTTCGTACTATGACGATGACGACTCTGACGATACGAAGAGAAATCCCGTGCGTAGAGTAAATTCATCACCAGAAATGAGATCAAATTGGAAACTTAATATGGCAAAACAGGCAGCTCGTAGTGAAAAAGACAGCAAATCTGCATCAAGTTCAACAGTTACTGATGACCAGGAGGAAAAAAGCGAAAGCGGAGAAATGCAACAGAAGAAAAAGTCTAGCTACTCGAAGGAAACTAAAGTCAGTTGCGAGGCTATTCCCGAGGAAATAAGCACTTTGGGTCAAAAAGAGGAATCAGCCGTTTTGAATGTGGATAAGGTTACTCGTCCTGTGCAGTTGCTATCGTCGATCTCAGCTCAGGAGCCTGCAAACGTAACTTCAATTCCAAAGAAGCAACATTCGGCTGATGACACCATACAGTTAAGAAGATCGGATACAATTTCCGTTAGTACGATTGCGCAGGCGAATTTAAGGAATCAGGAATGGACTTCGACGTCTATGTCATCAAGCAATTTGCCTCTATCGCCTCGTTATAAAGCTACAGTTAGCCGTCAAGTTAGTCATCAAGTTCCATTAGAGAGTGGAGGTGACGATGGCGGGTATCGTGCACGCTCAAAGACCATTTCAGTCATTGGAAGGAATAAAGAAGTTTTCGAAAACCCATCTCGAGCCGCTTCTGATTTTTCAACTTCAACGTCATCTATTGAGCAGACTCAGCCTGTCGCAACATCAGGAATCTGCCCAAGTTTTGTCTTTGTTCAGTTGTTCAACACTGGAAAAATGGAAATTGGAGCTGATAAACCGCTCCCCGTTAGCGACAAGCACATGGGAACATTAAACCTCCTGGATCTTATTCCTCCTTATGAAATTCATAAAATTGGAGTGATTTACGTCAAACCAGGACAAGCAAATAATGAAACTGAGATCCTGCGAAATACAAACGGAAGCTTGCGCTACATGCAATTTCTTCAAAATTTGGGCACTCTCATAGCGATCAAAGATGCTAAGGAGAAAAAACTCTTTGTGAACATGGAACCAAAGCGCGAGGGAAACTTCACTTATGTGTGGCATGATGATATCATTCAGATGACTTTTCACGTTGCAACACTGATGCCAACGCTTGAATCGGATCCTAACTGCAATGAAAAAAAGAAATATATTGGAAACGACTTTGCAACTATTGTTTATAACGAGAGCGGCGAAGATTATAATCTTAATACAATCAAAGGTCAATTTAATTACGCTTGTATTGTTGTACAACCTCTGGAGATGGGATCAAATTTGATATCTATTCGAGCTAAAGGTGATATCGAGGAATACTTTAAGCATCACGAACCAAAAATTATTTCTGATCGCGGTGCACCACTGCTCGCCCGTCAACTTGCACTTCACGCCAATATGGCCTCGCTGGTGTCAACTTCGCTGAAGAATCCAAAAATTCCGTATGCAAATAACTGGTTAGAGAGATTGCGCAAAATAAAGTTGCTTAAAAATCGCATTGCAAAGGAATTGGATCAAACTATTGTTCCCACGACAACAGCGTCATCAATAGCTACAACATCATTTTTAAAGGACGTTTTCACAAAATATACA
Protein: 1716 (aa)
MSKNLDKLKQFFRSNKVSGGQERVHVLTTELERELRKDNSLEKRLKLLKDLSDVVSTNRLEEFAVQKLWSLTNDLLEPNKEPYVREATLMFYTKLIQGQYRDLAIMRAHFFKLVQNHKISSDLPACLQMLKTLTENGRDIQNFEEEIGSFMLGWMDQIVEAQLTASYLDLFVNLIKYNTAYIDREVIIKVVQRVCNDICFKFLDDRETFLQCLNVIETVICYSVFPNEILSVCIIVLCRAVNFEMYVEPSYKIMRNLLGTQLGYASLLIMCNMLKEHAYYHDAYVLRGGVFHTNMNLWGGNNSSLQNGVKYSSVVLSSYCEVLKSRSIIVTYEVILSLQTLIVKCGSNLSEPSWDIIIETINRILDNIEYENLPDHSDIMTRLHAMFDSLETLIIQHECNVNVNVDRVYAVIERISNKRPESSVINLINHKASKLNTMSSGWVKNLNCFMERFYRNENSQSIRLATIDHLKEFINLNRTCYEEEILEKVVIVVFSDIAQEPDVKIRVSVCKLLLEICSHCDTKRCIELLDILEKVMNHPFDIYLLNSTALKSEHDFEDSIVVVNGMIDLFLEKLHQLPTSHAIKIYYILIGHLETHYQQPKVFEHATKMRYSIINWMLRVRANSSFQIGYPSPRLISENIKYSHYLAVEGEFQHPPPQTPNIQEIQNTGEEKQEGPFNFNTLTTLSIKRGCKIIVKCLDQEKDWHTVQLVLRELPKIMQNKTLIQGNDVDILARSLSELFRISYGKEKLMERFSTLNEQKDFRSLVMPAIASLITYNSFLSPLTKKKIVEILKSEVRMDGSLSICVQAFTILLMERCDIFERQLADIVLAISKVSDTMLVAIPILEFMSTITHLPYSFTNLNQKQFSYVFATCLPYTSPARYDHYVVSLAHHIIASWFLKSRLQWRKQYADYIIEGIAKNIDKSMQDAKHLQRQTQDDANKGFQLVNEDSAHRKRSSSLTEQSNRRREINNPQIMKMKAQRAALHTLSPSFDMHSFHIELIETCIDFMTRHTYSLSLALPRRLPSANYLLRGGGQSKTWVVGHVVITITTNACMDNHDWTSCSCFCSDWAEITIRRPTGMLSWMMKFQNQVGAFANEFSFHDLKGLFTDYELDPENPSGVLVKKKNEDFKSDEAALLMEKLSIGDDFNKIPLQATASDSAVSTIVTQPINIPSSKPETEQSAAEDDASYYDDDDSDDTKRNPVRRVNSSPEMRSNWKLNMAKQAARSEKDSKSASSSTVTDDQEEKSESGEMQQKKKSSYSKETKVSCEAIPEEISTLGQKEESAVLNVDKVTRPVQLLSSISAQEPANVTSIPKKQHSADDTIQLRRSDTISVSTIAQANLRNQEWTSTSMSSSNLPLSPRYKATVSRQVSHQVPLESGGDDGGYRARSKTISVIGRNKEVFENPSRAASDFSTSTSSIEQTQPVATSGICPSFVFVQLFNTGKMEIGADKPLPVSDKHMGTLNLLDLIPPYEIHKIGVIYVKPGQANNETEILRNTNGSLRYMQFLQNLGTLIAIKDAKEKKLFVNMEPKREGNFTYVWHDDIIQMTFHVATLMPTLESDPNCNEKKKYIGNDFATIVYNESGEDYNLNTIKGQFNYACIVVQPLEMGSNLISIRAKGDIEEYFKHHEPKIISDRGAPLLARQLALHANMASLVSTSLKNPKIPYANNWLERLRKIKLLKNRIAKELDQTIVPTTTASSIATTSFLKDVFTKYT
| Type | Start | End | Length |
| CDS |
26333 |
26527 |
195 |
| CDS |
26584 |
26754 |
171 |
| CDS |
26861 |
26975 |
115 |
| CDS |
27035 |
31447 |
4413 |
| CDS |
31520 |
31587 |
68 |
| CDS |
31640 |
31825 |
186 |
| intron |
26528 |
26583 |
56 |
| intron |
26755 |
26860 |
106 |
| intron |
26976 |
27034 |
59 |
| intron |
31448 |
31519 |
72 |
| intron |
31588 |
31639 |
52 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
EFR29842 |
hypothetical protein AND_00922 [Anopheles darlingi] |
0.0 |
| InterPro |
IPR018515 |
Tuberin-type domain |
|
| InterPro |
IPR003913 |
Tuberin |
|
| InterPro |
IPR011989 |
Armadillo-like helical |
|
| InterPro |
IPR016024 |
Armadillo-type fold |
|
| InterPro |
IPR000331 |
Rap/ran-GAP |
|
| InterPro |
IPR024584 |
Tuberin, N-terminal |
|
| Gene Ontology(BP) |
GO:0043547 |
positive regulation of GTPase activity |
|
| Gene Ontology(BP) |
GO:0051056 |
regulation of small GTPase mediated signal transduction |
|
| Gene Ontology(CC) |
GO:0005622 |
intracellular |
|
| Gene Ontology(MF) |
GO:0005488 |
binding |
|
| Gene Ontology(MF) |
GO:0005096 |
GTPase activator activity |
|
| Pfam |
PF11864.3 |
Domain of unknown function (DUF3384) |
1.3e-75 |
| Pfam |
PF03542.11 |
Tuberin |
7.8e-117 |
| Pfam |
PF02145.10 |
Rap/ran-GAP |
9.9e-38 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| B. mori |
BGIBMGA005686-TA |
| H. sapiens |
ENSP00000344383 |
| H. sapiens |
ENSP00000248099 |
| N. vitripennis |
NV10456-PA |
| M. musculus |
ENSMUSG00000002496 |
| H. melpomene |
HMEL013105-PA |
| H. sapiens |
ENSP00000219476 |
| H. sapiens |
ENSP00000371978 |
| D. plexippus |
DPOGS209357PA |
| A. aegypti |
AAEL007712 |
| S. invicta |
SI2.2.0_03091 |
| A. mellifera |
GB14209-PA |
| H. sapiens |
ENSP00000384468 |
| H. sapiens |
ENSP00000399232 |
| D. melanogaster |
FBgn0005198 |
| C. quinquefasciatus |
CPIJ007912 |
| S. invicta |
SI2.2.0_14221 |
| A. gambiae |
AGAP011123 |
| P. vanderplanki |
Pv.10269 |
| T. castaneum |
TC006755 |
| P. humanus |
PHUM422030-PA |
| S. invicta |
SI2.2.0_12588 |
| H. sapiens |
ENSP00000454487 |
| H. sapiens |
ENSP00000455817 |