MidgeBase gene description page [Pn.07930]

Outline

Link to gbrowse

Gene ID Pn.07930
Type Protein coding gene
Scaffold PnScaf7468
Start 14584
End 20067
Direction +

Sequence

Transcript: 2769 (bp)

 ATGTATCGAAATCTGATCAAAAGTGTTCAAACTCACAAGAAATTTGTCAAATTTGCCAATGCTTCATATCATAATGAGTCAACTTACTATGGCTATCGTCCGAAAGTCAAAATGGAGTGGAAACTTCCAGAAGTTCATGTACAAGCTCGAAAGATTAACCCAAATATTAATGCTTGGATCAATGCATATCGAATGCACGGTCATCGAATTTCGACAGTTGACCCTATCAAATGGCTTGATGGTAAAGAAGAAGTACCTGAGTTAGAAAATGTACGTTATGGACTTGAGGAATCACAAGAACTTTCAGGGCTCGAAGGACTCGTTTCGTTTATCGCTCCGGAAGTAAAAACTGTTAAAGATCTTAAAAGAAAGCTTATTGAAACCTACTGTGAAAACATTTCTGCAGAATTTTTGTACATAGAAAATGAGTTTGAACGAGAATGGTTTACCGAAAATTTTGAAAAAATATTAGATGAGAAGGCCTTTATCACCAATGAAGAAAAACGGGATTTTGCAACAACAATGCTTCAATACCAAGAGTTTGATAGATTTATGAATGCAAAGCTGCCAGCAATTAAGCGTTATGGAGGGGAAGGAGCTGAAGCAATGGTCGCATTTTTCATAACACTTCTTAAAAATGCAGCTCTCGATGATGTGTCAAATATTGTCCTCGGAATGCCGCACAGAGGGAAATTAAATGCTCTCGTGTCCCTTTTTAGACATCGACCAGCAAGAATATTTAGAAAATATAAGGGACTTCCAGAATTCAAAGACGACATCAAAGCTATGATGGACATCACAAATCATTTCAGCGTTTCCGAGGATTACGAATTTGATGGCAAAACTGTTCACCTTTCAATGCTTCCGAATCCATCGCATCTTGAAGCAGTTAACCCTGTGTCCATGGGAAAAACTCGATCTAAGCAGCAGAGTCTTAGGGATGGTGCATTTAACGATGACCAGCTCAAGCTTTTTGGTTCAGATGTGATAAACGTTCAATTGCATGGTGACGCAGCAATTTCAGGCCAAGGCGTCAACCAGGAGTGTGTCATGATGGCAAATACACCGAATTTTGATATAGGCGGCACCTTGCACTTGGTTATAAATAATCAAATTGGCTATACAACACCAGGCGACCGTGGTCGTGCCAGTCGATATTGCACTGACATTGCAAAATCAATTAATGCTCCAGTTATTCACGTGAACAGTGATGATCCTGAATTGGTGGGACTCGCAACAAAACTCGCTTTTAGATATCAAAGAATGTTTCGTAAAGACATTTTCATTGATTTTAACTGCTTCCGCAGAATGGGTCATAACGAAGTTGATGATCCAACCGTAACCAATCCTTGCATGTACAAATTAATAAGAGATAAACGAACTATTCCGGATATTTACGCGCAAAAATTAGTTGACGAAGGAGTTATGACAGAAAGTGAAATTAAAGCGATTTGTCAAAAACAATTTGATTACTATTCCTTGGAGATGCAGCAAGCAGAGTCATTTGTGCCAGAAGATTCATACTACTTCAAGAAACAATGGGAAGGCTTTGTACAGGCACCTAGTGACATTACCATCTGGGATACCGGTGTAAGCTGGGAACTACTTAGTTTCATTGGCCGAAGTTCAGTTTACTATCCTCCGAATTTCAATATCCACCCACATATCAAAAAAACATTTGTGAATGCCAGAATAAAAAGGCTTGCGGAGGGAAATTCAATCGATTGGGCCACAGCGGAAGCTCTCGCGTTCGGCAGTCTCATGTACCAAGGACATAATGTAAGATTGTCGGGCGAGGATGTTGGCCGTGGAACTTTTGCTCAGCGACATGCGATGCTAATTGATCAAGAGACAAATGAAGTCTGCGTGCCGTTGAATACATTAAAAGGTGGATTAGGTGGCAAATACGAGGTGGCCAACAGCATTTTATCAGAGGAAGCGGTACTAGGTTTTGAGTATGGAATGAGCATCGATAGCCCAAATAATCTCATAATTTGGGAAAGTCAATTTGGCGATTTTTACAACGGTGCGCAAATAATATTCGATCAATTTGTTGCAAGTGGTGAAACAAAATGGATGACGTCAAGTGGCCTTGTTATGCTACTTCCTCATGGAATGGATGGGATGGCATCTGAGCACTCCTCGTGCCGAATGGAAAGGTTTCTCCAAATGACAGATTCTAAAGAAACTACCCCTGATGGAGATGATGTAAACTTTAACGTAATCTTTCCCTCCACCCCAGCACAATATTTTCACGCTATTCGGCGGCAAATCATTAGAAATTTCCGAAAGCCCCTCGTGGTAGTCGGACCTAAAACTCTTCTGCGCATGTCAGAAGCTACATCTTCATTCCAAGATTTTCAACCAGGCACTCACTTTAAGAACGTGCTAGGTGATGATGTCGCAAACTCTAAGACCGTCAAAAGGATAATCTTTTGTACTGGAAAGCATTACTATGCACTAAATAATGAGAGAATCTCAAGGAATATAGAGGATGTGGCAATTATACGACTTGAATCTCTTTGCCCATTCCCTGTACACGATATTCAAGTTGAACTTGCTAAATATAAAAACTCTGCAATTTGCATTTGGAGTCAAGAAGAACATCGTAACATGGGAGCCTGGAATTTCATTCAACCTAGATTTGAAAACATGTGTGGAAGACGAATTAAGTACTCAGGAAGAAAAGAAGCAGCCACACCCGCAGTCGGAATTGGAAAAGTTCACGCTCAAGAAGCCATCTATGTTGCATCACATCCCTTTACGATG 

Protein: 923 (aa)

 MYRNLIKSVQTHKKFVKFANASYHNESTYYGYRPKVKMEWKLPEVHVQARKINPNINAWINAYRMHGHRISTVDPIKWLDGKEEVPELENVRYGLEESQELSGLEGLVSFIAPEVKTVKDLKRKLIETYCENISAEFLYIENEFEREWFTENFEKILDEKAFITNEEKRDFATTMLQYQEFDRFMNAKLPAIKRYGGEGAEAMVAFFITLLKNAALDDVSNIVLGMPHRGKLNALVSLFRHRPARIFRKYKGLPEFKDDIKAMMDITNHFSVSEDYEFDGKTVHLSMLPNPSHLEAVNPVSMGKTRSKQQSLRDGAFNDDQLKLFGSDVINVQLHGDAAISGQGVNQECVMMANTPNFDIGGTLHLVINNQIGYTTPGDRGRASRYCTDIAKSINAPVIHVNSDDPELVGLATKLAFRYQRMFRKDIFIDFNCFRRMGHNEVDDPTVTNPCMYKLIRDKRTIPDIYAQKLVDEGVMTESEIKAICQKQFDYYSLEMQQAESFVPEDSYYFKKQWEGFVQAPSDITIWDTGVSWELLSFIGRSSVYYPPNFNIHPHIKKTFVNARIKRLAEGNSIDWATAEALAFGSLMYQGHNVRLSGEDVGRGTFAQRHAMLIDQETNEVCVPLNTLKGGLGGKYEVANSILSEEAVLGFEYGMSIDSPNNLIIWESQFGDFYNGAQIIFDQFVASGETKWMTSSGLVMLLPHGMDGMASEHSSCRMERFLQMTDSKETTPDGDDVNFNVIFPSTPAQYFHAIRRQIIRNFRKPLVVVGPKTLLRMSEATSSFQDFQPGTHFKNVLGDDVANSKTVKRIIFCTGKHYYALNNERISRNIEDVAIIRLESLCPFPVHDIQVELAKYKNSAICIWSQEEHRNMGAWNFIQPRFENMCGRRIKYSGRKEAATPAVGIGKVHAQEAIYVASHPFTM 
Type Start End Length
CDS 14584 14707 124
CDS 15535 16221 687
CDS 16456 16742 287
CDS 17462 17742 281
CDS 17813 18083 271
CDS 18153 18570 418
CDS 18645 19271 627
CDS 19991 20064 74
intron 14708 15534 827
intron 16222 16455 234
intron 16743 17461 719
intron 17743 17812 70
intron 18084 18152 69
intron 18571 18644 74
intron 19272 19990 719

Auto annotation result

Program/Analysis Accession Description Score/Expectation
BLASTP/NCBI-nr XP_001650884 2-oxoglutarate dehydrogenase [Aedes aegypti] gb|EAT43084.1| 2-oxoglutarate dehydrogenase [Aedes aegypti] 0.0
InterPro IPR011603 2-oxoglutarate dehydrogenase, E1 component
InterPro IPR001017 Dehydrogenase, E1 component
InterPro IPR005475 Transketolase-like, pyrimidine-binding domain
Gene Ontology(BP) GO:0006099 tricarboxylic acid cycle
Gene Ontology(BP) GO:0008152 metabolic process
Gene Ontology(BP) GO:0055114 oxidation-reduction process
Gene Ontology(MF) GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity
Gene Ontology(MF) GO:0030976 thiamine pyrophosphate binding
Gene Ontology(MF) GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Pfam PF00676.15 Dehydrogenase E1 component 1.3e-37
Pfam PF02779.19 Transketolase, pyrimidine binding domain 4.8e-62
Pfam PF07535.7 DBF zinc finger 0.2
Pfam PF14401.1 RimK-like ATPgrasp N-terminal domain 0.076

Expression level (RPKM)

Paralog/Ortholog genes

Paralogous genes

Gene ID
Pn.08913
Pn.08912

Orthologous genes

Species Gene ID
A. aegypti AAEL005429
B. mori BGIBMGA006311-TA
D. melanogaster FBgn0039827
A. mellifera GB13923-PA
H. melpomene HMEL010125-PA
N. vitripennis NV12866-PA
H. sapiens ENSP00000263035
H. sapiens ENSP00000398576
A. aegypti AAEL006721
H. sapiens ENSP00000390240
C. quinquefasciatus CPIJ007338
T. castaneum TC008732
H. sapiens ENSP00000392878
S. invicta SI2.2.0_08248
H. sapiens ENSP00000222673
D. plexippus DPOGS208941PA
D. melanogaster FBgn0035240
H. sapiens ENSP00000363216
T. castaneum TC030624
P. vanderplanki Pv.00465
A. gambiae AGAP000551
M. musculus ENSMUSG00000021913
D. plexippus DPOGS202452PA
S. invicta SI2.2.0_11249
C. quinquefasciatus CPIJ017085
M. musculus ENSMUSG00000025815
P. humanus PHUM304130-PA
D. plexippus DPOGS210696PA
A. gambiae AGAP006366
A. mellifera GB12855-PA
P. humanus PHUM315960-PA
H. sapiens ENSP00000388183
H. sapiens ENSP00000414662
A. mellifera GB15468-PA
B. mori BGIBMGA002883-TA
P. vanderplanki Pv.13880
P. vanderplanki Pv.07252
B. mori BGIBMGA009974-TA
T. castaneum TC012622
P. humanus PHUM601630-PA
H. sapiens ENSP00000443821
H. sapiens ENSP00000401356
H. sapiens ENSP00000388084
D. melanogaster FBgn0010352
N. vitripennis NV17458-PA