MidgeBase gene description page [Pn.07753]
Outline
| Gene ID | Pn.07753 |
| Type | Protein coding gene |
| Scaffold | PnScaf7175 |
| Start | 38967 |
| End | 44999 |
| Direction | - |
Sequence
Transcript: 2796 (bp)
ATGATGGATCAAAATGGCTTGTATGCTGAAGAATATGGAGAAAACGGATATATGGAGCAAGAAGAGGAGTGGGAGAGAGAAGGCTTGCTAGATCCAGCATGGGAGAAACAACAAAAAAAGACCTTTACCGCTTGGTGCAACAGTCACTTAAGAAAGGCCGGAACTTCGATCGATAATATCGAGGATGACTTCCGCAATGGTCTCAAGTTGATGCTTCTCTTAGAAGTCATTTCTGGCGAGACGCTGCCAAAACCCGACCGCGGCAAGATGCGCTTTCACAAAATTGCAAATGTGAACAAAGCTCTTGACTTCATCGCGTCGAAGGGTGTCAAGCTCGTCTCAATTGGAGCAGAAGAAATTGTCGATGGAAACTTAAAGATGACTTTAGGTATGATTTGGACAATCATCTTGAGATTCGCCATCCAAGACATTTCCGTCGAGGAGATGACAGCTAAGGAAGGCTTATTGCTCTGGTGCCAACGCAAAACTGCTCCATACAAGAACGTCAACGTTCAAAACTTCCATCTCAGTTTCAAGGATGGTCTGGCCTTCTGTGCTCTCATCCATCGCCATCGTCCAGATTTGATTGACTACTCAAAATTGTCAAAGGACAATCCTTTGGAGAACTTGAACACTGCATTTGATGTTGCAGAGAAGTACTTGGATATTCCAAGAATGTTAGATCCTGATGATTTGATCAATACGCCTAAGCCGGATGAAAGAGCAATCATGACATACGTGTCATGCTATTATCATGCCTTCCAAGGCGCTCAACAGGTTCGCATTATATGCTTGTACTTACAAAACACTGCAATGCCCGATGAACGTGCAACAATGACCTATGTCTCATCTTACTATCATTGCTTTAGTGGCGCTCAAAAGGCGGAAACTGCAGCTAATCGCATCTGCAAGGTTCTCAAAGTCAACCAAGAAAATGAGAGACTCATGGAGGAATATGAACGTCTTGCATCCGATCTTCTCGAATGGATCCGTCGCACAATGCCGTGGTTAGCGTCCCGCCATTCCGACAGCACACTCGCTGGCGTCCAGAAGAAACTCGAGGAGTATCGCACTTACAGACGCAAGCACAAGCCACCACGTGTCGAGCAGAAGGCGAAGCTAGAAACCAATTTCAACACCCTTCAGACGAAGTTGCGTCTATCAAATAGACCGGCATACATGCCAACTGAGGGCAAGATGGTTTCGGACATCGCCAATGCCTGGAAGAACTTGGAACTGGCCGAGAAGGCCTTCGAAGAGTGGCTCTTGGCCGAGACCATGCGTTTGGAACGCCTGGAGCATTTGGCACAAAAGTTCAAGCATAAGGCCGACACGCACGAGGAATGGACTCGTGGTAAGGAGGAGATGCTCCAGTCTCAAGACTACCGTAGCTGCCGCTTGTACGAGCTGAAGGCTCTCAAGAAGAAGCACGAGGCCTTCGAGTCCGACTTGGCCGCCCACCAAGACCGCGTCGAACAGATTGCTGCCATCGCTCAAGAGCTCAACACATTGGAGTATCACGATTGCGTCACTGTCAATGCACGCTGCCAGCGCATTTGTGACCAATGGGATCGCTTGGGCGCCTTGACTCAACGCCGTCGTCAAGCGTTGGATGACTCTGAGAGAGTCCTCGAAAAGATTGACTTGCTGCACTTGGAATTCGCCAAGCGTGCTGCTCCATTCAACAACTGGTTGGACGGTGCTCGCGAGGACTTGGTTGACATGTTCATTGTCCATACAATGGAGGAGATTCAAGGTCTCATCACCGCCCACGATCAATTCAAGGCGACTTTGGGCGAGGCCGATAAGGAGTACAATCTCATTGTTGGCTTGGTCCGCGACGTCGAGGGCTTGGTCAATCAATACCAAATCGCAAACGGATTGGAGAATCCCTACACCACACTCACCGCAAGAGATTTGACATCGAAATGGGCCGATGTGAAGACACTCGTTCCCGCCCGTGATCAGACACTTGCCATGGAACTCAAGAAGCAACAGAACAATGAGATGTTGCGTCGCCAGTTCGCCGAGAAGGCCAACAACGTCGGCCCATGGATCGAGAAGCAAATGGACGCCGTCAGCGCCATCGGCATGTCGATCAGCGGCTCATTGGAGGAGCAATTGCACCGATTGAAGGAGTACGAGCAAGCCGTCTACGCCTACAAGCCTCACATTGAGGAGTTGGAGAAGATTCATCAGGCAGTACAAGAATCTATGATCTTTGAGAACCGCTACACGAACTACACAATGGAGACATTGCGCGTCGGCTGGGAGCAGCTCTTGACTTCAATCAACAGAAATATCAATGAGGTCGAGAACCAAATTCTCACACGCGACTCGAAGGGAATCACACAAGAGCAATTGACAGAATTCCGCTCAAGCTTCAACCACTTCGACAAGAACCGCACCGGTCGCTTAGCTCCCGACGAATTCAAATCGTGCTTGGTCTCGATTGGCTACTCCATCGGCAAGGACAGACAAGGAGAATTAGATTTCCAACGTATCTTGGCAGTCGTCGATCCAAACAGCACCGGCTTCGTACACTTTGACGCTTTCCTTGACTTTATGACACGCGAAAGCACCGACACCGACACCGCTGAACAAGTCATTGACTCATTCAGAATCTTGGCCTCCGACAAGCCGTACATTCTTCCCGATGAACTTCGACGCGAGTTGCCACCAGATCAAGCTGAGTACTGTATCCAAAGAATGCCACCATTCAAAGGGCCCGGTGCCGTGCCAGGTGCACTTGATTACATGTCATTCAGTACTGCTCTTTATGGCGAATCTGATCTG
Protein: 932 (aa)
MMDQNGLYAEEYGENGYMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTSIDNIEDDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYSKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQVRIICLYLQNTAMPDERATMTYVSSYYHCFSGAQKAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLASRHSDSTLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYMPTEGKMVSDIANAWKNLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADTHEEWTRGKEEMLQSQDYRSCRLYELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVTVNARCQRICDQWDRLGALTQRRRQALDDSERVLEKIDLLHLEFAKRAAPFNNWLDGAREDLVDMFIVHTMEEIQGLITAHDQFKATLGEADKEYNLIVGLVRDVEGLVNQYQIANGLENPYTTLTARDLTSKWADVKTLVPARDQTLAMELKKQQNNEMLRRQFAEKANNVGPWIEKQMDAVSAIGMSISGSLEEQLHRLKEYEQAVYAYKPHIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGITQEQLTEFRSSFNHFDKNRTGRLAPDEFKSCLVSIGYSIGKDRQGELDFQRILAVVDPNSTGFVHFDAFLDFMTRESTDTDTAEQVIDSFRILASDKPYILPDELRRELPPDQAEYCIQRMPPFKGPGAVPGALDYMSFSTALYGESDL
| Type | Start | End | Length |
| CDS |
38970 |
39125 |
156 |
| CDS |
39193 |
39522 |
330 |
| CDS |
39597 |
40224 |
628 |
| CDS |
40296 |
41002 |
707 |
| CDS |
41068 |
41160 |
93 |
| CDS |
41321 |
41406 |
86 |
| CDS |
41668 |
41772 |
105 |
| CDS |
41911 |
42021 |
111 |
| CDS |
42110 |
42152 |
43 |
| CDS |
42224 |
42478 |
255 |
| CDS |
42553 |
42714 |
162 |
| CDS |
44880 |
44999 |
120 |
| intron |
39126 |
39192 |
67 |
| intron |
39523 |
39596 |
74 |
| intron |
40225 |
40295 |
71 |
| intron |
41003 |
41067 |
65 |
| intron |
41161 |
41320 |
160 |
| intron |
41407 |
41667 |
261 |
| intron |
41773 |
41910 |
138 |
| intron |
42022 |
42109 |
88 |
| intron |
42153 |
42223 |
71 |
| intron |
42479 |
42552 |
74 |
| intron |
42715 |
44879 |
2165 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
P18091 |
RecName: Full=Alpha-actinin, sarcomeric; AltName: Full=F-actin cross-linking protein emb|CAA21121.1| EG:133E12.1 [Drosophila melanogaster] emb|CAA15689.1| EG:133E12.1 [Drosophila melanogaster] |
0.0 |
| InterPro |
IPR014837 |
EF-hand, Ca insensitive |
|
| InterPro |
IPR018247 |
EF-Hand 1, calcium-binding site |
|
| InterPro |
IPR002017 |
Spectrin repeat |
|
| InterPro |
IPR011992 |
EF-hand-like domain |
|
| InterPro |
IPR002048 |
Calcium-binding EF-hand |
|
| InterPro |
IPR001715 |
Calponin homology domain |
|
| InterPro |
IPR001589 |
Actinin-type, actin-binding, conserved site |
|
| InterPro |
IPR018249 |
EF-HAND 2 |
|
| InterPro |
IPR018159 |
Spectrin/alpha-actinin |
|
| Gene Ontology(MF) |
GO:0003779 |
actin binding |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0005509 |
calcium ion binding |
|
| Pfam |
PF00307.26 |
Calponin homology (CH) domain |
2.4e-40 |
| Pfam |
PF11971.3 |
CAMSAP CH domain |
1.7e-14 |
| Pfam |
PF08726.5 |
Ca2+ insensitive EF hand |
3.9e-26 |
| Pfam |
PF13499.1 |
EF-hand domain pair |
0.00011 |
| Pfam |
PF00036.27 |
EF hand |
4.1e-08 |
| Pfam |
PF00435.16 |
Spectrin repeat |
7.7e-66 |
| Pfam |
PF13833.1 |
EF-hand domain pair |
0.025 |
| Pfam |
PF13405.1 |
EF-hand domain |
3.8e-06 |
| Pfam |
PF09051.5 |
Stannin cytoplasmic |
0.14 |
| Pfam |
PF13202.1 |
EF hand |
0.034 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000438384 |
| H. sapiens |
ENSP00000422007 |
| H. sapiens |
ENSP00000414272 |
| P. vanderplanki |
Pv.02444 |
| H. sapiens |
ENSP00000252699 |
| N. vitripennis |
NV50254-PA |
| A. aegypti |
AAEL007306 |
| H. melpomene |
HMEL008833-PA |
| D. plexippus |
DPOGS206602PA |
| C. quinquefasciatus |
CPIJ019577 |
| M. musculus |
ENSMUSG00000006457 |
| T. castaneum |
TC007894 |
| A. gambiae |
AGAP001497 |
| P. humanus |
PHUM299510-PA |
| H. sapiens |
ENSP00000355537 |
| H. sapiens |
ENSP00000366035 |
| H. sapiens |
ENSP00000443495 |
| H. sapiens |
ENSP00000411187 |
| A. mellifera |
GB11028-PA |
| H. sapiens |
ENSP00000398393 |
| M. musculus |
ENSMUSG00000052374 |
| H. sapiens |
ENSP00000439497 |
| H. sapiens |
ENSP00000426797 |
| S. invicta |
SI2.2.0_01199 |
| D. melanogaster |
FBgn0000667 |
| M. musculus |
ENSMUSG00000015143 |
| H. sapiens |
ENSP00000193403 |
| H. sapiens |
ENSP00000377941 |
| H. sapiens |
ENSP00000439828 |