MidgeBase gene description page [Pn.07213]
Outline
| Gene ID | Pn.07213 |
| Type | Protein coding gene |
| Scaffold | PnScaf6516 |
| Start | 319 |
| End | 11191 |
| Direction | - |
Sequence
Transcript: 5802 (bp)
ATGAAATCACCAGAGATGCATCTATACACGAGACAGAGAAGATTTGCTTTGATTCTGATGAAGGCTGGCTTGAAGGCAGCTCTACGTGGCGCATTAATTAGTCGAGCCGAGACGCAAATCCTCATAGCATCCTTAGCATCCACGCCGCCCTTCTCGAGCGATCTAGAGGAGCTGCAGAACATCTTGCATTTCCCCGAGGAGGTGGCGTTGCGTCTAACCGATGCCGAATATCAGTTGTATTATCAGACTTCAGTTGCTGATTTTATTATCGAGTCAATTTATGATTTACAAGGGAAGGTCAACGATGAGCGCGTAAATTCACCAATAAGAAACCTTCGAAAACGCTTTGACGATGTCAGCTCGTGGACTACCTACATCGTTCTATCGCAACTGTTGCCGGACGAACGACGTGCGGCATTCGGATGCTTGTTACGTGTTGCAATATCTTGTTGGAATATTGGAAATTTTATTGGCGCAAAGGAAATCATCACGGGTCTTAGTGGGGAGTGGAGACCCAAAATCTATATATTTTCGGTGCGAATAGTGACGTATGAGAAATTGCGAGGAACGAAATCGAGCGCAGGGGTTTCAATCAGCCTTCGATTTCTTCAGAGCAAATCACTTTGGTCGTCAATTACGGAGAACAAGAGGATATCCTGCTACGACTTTCTGTGTTCCGCATTCGATTCAGCGGTCTACGAGAAAAATCTGTCCCGTGCCATAGAGATATCGACATGTCGCGTAATACCGTACTTTAAGTTTTATCTCGACAAATTAAAAATCGCCTTATCATCGTCAAAGTCATTCTCATTTACGTCGGGTTCAATCGAGGAGATTTGTGCGAAGCTTAAGAAACGTGAAAAGATTCCAGATATCGAGTGCTTGGAGCAAATGGAGATCATAAAGAGTGAAATTGACTTATTTTTAGAGCATCATCAAGCTCTGTGTCAACAAACATCGCCTAGTTTATACGATTATTTGAGACAAGCATCGAACACACCTAGACACTTGAACAATGAATTGAATCAAACACTACACGAGGTCGACGAGGACTACGAATTAGAAATTGGAAATTATAACCCAGTACAAACGTTATTTAATGATCATGGCATTAGCTTAATTTCATTATCGTCTACCGACTACAATAAAATAGATCATCATTTACTGCAAATACTACATCATGGAACAACCGCGGTTTTATGGGAACCTGATACGCAAACGGGCTCATCATATGTTTACTTTCGACTCGAACGATGCTGCTCGATTGTCTCGTGGCAACGACCGGCGTGGCGTCGCATCAAGTCTCAGATGGACTTCAACGTCGCAATCAATCCCGAGGAGAACGTCGTGCCGCGCACTGTCACCAAGCCCGTCTATAACATGAACGACATCGACGGCATCTTTCATACGCTCGACGAGGGCATCCTGGATCTGGCGACGGTCAAGGACATCTCGATGGGATCGAGAAACCAAGATTACAATCAGGATATTCTGGCCGCCGGCAGACGCTACGGACTGACGCACGTCGAGAGCTGTGTGTCCATTCTGTACGGGACTTCGCTGAACGAGAATCGAATTCTCTGCATCTTGTGCCCTCCGATGTTAGCTAGATTATGGTACGTTGGATTAACGTGTATGTTACGAGGTATCAGAAAGCAAATTAGTCTCATTGATCGATCAATGCTGTGGCTTAAGGAGCTCTACATCCAACTTTTCTACGAAAACGGTGGATGTGAGCCGCTGGCGTCTGATGCGATAAGAGCATTTGGCGGAACAGATTATTCATTCTTGTCGACGACAACCTCCACGCCCGACTCGATTCACAGCATAAAGAAGGATATCGTGCAGCAACAGCAGCAGACGACGTCGCAAGCGACAAATCAACAGTCGACACCCACGTCGTCGTCGTCGTCGATGACGAGCAACAACATGAAGAAGAAGAAATCTATGGTGAATTTATTTACATGCGGACAACAATCGCAGACTTCCCCCTCGACATCGTCATTAGCGAACAACGCAACAATCAATTCGACATCAATGCACAATCAACAGCACGAGCATCAGCAAGTGACTCCGGCAACGGCAAATCAACAGCACCCGTCGATGTCGACTCCTTCATCTCTTTGTGATACAACAACAATTGTCTCGTCTAAACATTATAACGCATTTAACAACATATCATTTGATACTAATTTAGATTTTCTATCGTTTGTCTCACTCTATCGATCATTTAGTTTAATTGCACGAAAAGATTTACGTGATATATTTGACCAATTATCAGTAACTAGGAAGAGTAAAATAACATTAAATAGTGATAAAAGCCGAAGTGCACCTGAACTATTCCACGAGAAACCTGAGAAAAGAAAAATAGGACTACTAACGCGCAACAACTCGCTCGACTTTGAGCTCTCGCAATCGAAATACTCGCAGAAGAAGCTCTTTCATACGCTCATAAGGAATTTCGGCTATTGCGGCAATTACAGCCCATTAACGGCCATGCAAATCTCATCGGGCAATCCATCAATGTCGAGCAATTCGCAAGTGATTACGCTCGATACGTTCAAGAAGTTCTTGGAGACGCGTCAGATGGAGTCGAAGAGCGATGGCGAGATTAAGATGATAATTGAGCGCCACGAGCCGGATCAGAATTTGCGCACGGAAAATTTACTCAGCTTCGAGGGCTTTGCGCGCTACTTGATGGACAAAGACAACTACGCGATGACAAAGACCGTGTGCCCCACGAAGATGGCCGACCTGATGAACATGAACCTGCCGCTCTCGCACTACTTCATCGCGACGTCGCACAACACGTACCTCACGGGACACCAGCTGAAGGGCGAGAGCTCGGTGGAGCTGTACAGCCAGGTACTGCTGACGGGGTGCCGGTGCGTCGAGCTGGACTGTTGGGACGGCGACGACGGCTATCCGATCATCTATCACGGACACACGTTCACGTCGAAAATTCCGTTTCGCGCTGTCGTCGATGCCATCAATAAGTCGGCTTTTGTCGCGAGTCCTTATCCCGTGATTTTGAGCATCGAAAATCACTGCTCGATGCAGCAGCAAATTCGAATGGCGCAAATTTTTCAGACCACATTCGGTGATAAATTGGTGACGAAATTTATGTTCGATATCGACTACACGGACGAGCCATATCTGCCGACACCCGAGCAGCTCAAATACAAAATTATTGTGAAGAATAAAAAGATATTAGTGGACGTTCCCGTTGGAATCAGCTCGCCGAGGAGCCCGTACATGCGGCACCAGAGCAATTTGAGTGGGCGTGCGAGTTCAATAATATCCAACAGCTCGGCCGGGTCGTTGAACGAGGACTTCGAGGACAGCGACTACGAGGACGATGACGACATCGACAACTTTGACGACAAGACGTACAACATTTGGGGCTCGTCCGCCGACGACAAATACACGCGTCACAGCATAACGTCGTTCACGGCGAACGTGCGGAAGCTGGAGATGGAGGAGCGCTCGAAGAAGCGCAGCAATCAGATCGCGCGCGAGCTCTCCGACCTCGTCACGTACGTGCAGGCGATAAAGTTTCGCGGCCTCAACCCGTGGATCCACTACAATCTCAACCAGCGCAACGGCACCTCAACGCCGTCGGCCAGCGGCGCTCTCTCGACCTCCTCCACCACCATCGCCCTCACCGGCAACGTGACGTCCACAACGACGTCGAGCGCCTCGAGCGTCGTCACGACCGGCTCGACCATCAAGATCTTCACGACGGGCGACACGAGCGCCGAGACGGAGTCGAACACGTCGGGCGAGCAGGAGACGCTCTCGTCGTCGGCGTCGGCGTCCACGCAATACGGCAGCGGCAACAACGTCACGACCGTGCACAAAAAGTACCCGCACGCGAACGTCAACCATCCGTGCTATCAGTGCGCGTCGATAAACGAGGCGAACGCGAAGAAGATTTGCCGGAAGCATCCGCTGGCGGTGATTGCACACACCGAGACGCAGCTCATCCGCTCCTATCCGGCCGGCCTCCGCATCGACTCGTCCAACTTCAATCCGGTGTTTTTCTGGAGCTTCGGCATGCAGATGGTCGCGCTCAACTACCAGACCGAGGACCTGCCCATGCACATCAACCGGGCGATGTTCGAGCAGTCGAACAACTACGGCTACGTCTGCAAGCCGAGCATCATGTGGAACCGCTCGCATCTGATGTACCGGCGCTTCAATCCGCTCGAGAAGGAGTTCGACGGCTTGCACACGACGCAAATTGTTATAAATATTGTCAACGGGCAGTATTTGAACCAAAATAACTTGTTATCTAGTCCCTACATTGAAATAGAAATAATTGGAATTCCAGGTGATTGTTGTAAACGTAAAACGAAAGCAATAATGCGCAACGCATTCAATCCGATTTGGAACGAGACGTTTTATTTTCGCGTCAACTTCATCGATCTCGCCTTCATTCGCTTCGCCGTCTACGACTCCGACGGCGGCTTCATGCTCGCCCAGCGCGTCATGTCCATCAAGTCGCTGCGCTCGGGCTACCGGCACGTGTGCCTGCGCTCCTCCACCAACCTCCTCCTCAACATGGCGTCGCTCTTCATTTACTCGCGCATCGAGGAGGAGACCATCGACAGCTGCTACGACGAGTCGCTGATGGACCGCGCCAAGGCCGCCACGCTCTCGATCATGGAGTCGAAGCTGCTGAACAACCAGCTCAACAGCGAGAACGACAAGGGCAAGCGCAAGACGTTCTTCCTCACCGTGTACGGCGTGATCCCGGACGAGCCCTACACCATCCTGAAGGTCATTCAGGAGAGCTCCACGAAGGACGTGCTGCAGCAGGCACTGATGAAGGGCGGCATCCCGCTCGAGAACCTCAACGACTTCGTGCTGGTCGAGGAGGTCTTTCCCTCGTGGGAGAAGAAGGACCGCGCGCAGCCGCCCAAGCAGCGAATGCTCGACGCCAACGAGAAGCCGCTGCTGTCGCAGGCGAAGTGGAAGGGCGAGGGCCGGTTTATTCTCAAGAAAATCGGCGACGATCCGTCGAGTCGTGCGTGGCTCAGCACCGTGCGGCGAGTCGGCGCCGCCCTCGACCGGCAGTCCGACTACATGACCACGGCCTTCGCGAAGGAGAACCTCAAGATTTCGCCGTCGAGCGGCACGTCGAACTCCGCGAGCGACATGGCGCTCATCGAGAATGTGGAGCACTTTGTCGTTTGCGTGTACAACGTCTCGCCCGACATTCCGTACGCGATGCTGCGAGTGCCGCTGAAGGCGACGGCACAGGACGTGCTGGCGCAGGCACTGCTGAAGGCGCGCCGCTTCGACAATCCCAACAACTTCGTGCTGCTCGAGGAGATCCAGCCGAACAACGCGAACACGCCCGTGCATCAGCGCATCATGCAGCAGGACGAGAATGTGTACAAGACGCAAGCAAACTGGAAGACGCTCGGCCGCTTCATCATCCAGGAGCGCCAGTCGACGCCGTCGATTCTGAGGAAGGTGAAGTCGGTGGACAAGGGCAAGGGCCTGAGCATATCGCGGCCCTCGAAGTTTCCCATCCAGTCGATGCTCAGCGACCCCACGACGTCGCGCATCAAGGCAAAGTCAGCGGAATCGCACTCCGAGCGCAAGACCAAGCACAACAAGTACAGCCCCGACCAGCTCGACTCGTACGGCTACTCATCGCACCACCATCATCACCACCGGTCGCACTACTCCGAGGGTGAGACGCTCAGCGAGGAGGAGTCGAAGGACGACTTTCTCTCAACAATCACGCGACTCAAACGAATGTCCATGAAGAAGATCAAGTCGTGGAAGAAT
Protein: 1934 (aa)
MKSPEMHLYTRQRRFALILMKAGLKAALRGALISRAETQILIASLASTPPFSSDLEELQNILHFPEEVALRLTDAEYQLYYQTSVADFIIESIYDLQGKVNDERVNSPIRNLRKRFDDVSSWTTYIVLSQLLPDERRAAFGCLLRVAISCWNIGNFIGAKEIITGLSGEWRPKIYIFSVRIVTYEKLRGTKSSAGVSISLRFLQSKSLWSSITENKRISCYDFLCSAFDSAVYEKNLSRAIEISTCRVIPYFKFYLDKLKIALSSSKSFSFTSGSIEEICAKLKKREKIPDIECLEQMEIIKSEIDLFLEHHQALCQQTSPSLYDYLRQASNTPRHLNNELNQTLHEVDEDYELEIGNYNPVQTLFNDHGISLISLSSTDYNKIDHHLLQILHHGTTAVLWEPDTQTGSSYVYFRLERCCSIVSWQRPAWRRIKSQMDFNVAINPEENVVPRTVTKPVYNMNDIDGIFHTLDEGILDLATVKDISMGSRNQDYNQDILAAGRRYGLTHVESCVSILYGTSLNENRILCILCPPMLARLWYVGLTCMLRGIRKQISLIDRSMLWLKELYIQLFYENGGCEPLASDAIRAFGGTDYSFLSTTTSTPDSIHSIKKDIVQQQQQTTSQATNQQSTPTSSSSSMTSNNMKKKKSMVNLFTCGQQSQTSPSTSSLANNATINSTSMHNQQHEHQQVTPATANQQHPSMSTPSSLCDTTTIVSSKHYNAFNNISFDTNLDFLSFVSLYRSFSLIARKDLRDIFDQLSVTRKSKITLNSDKSRSAPELFHEKPEKRKIGLLTRNNSLDFELSQSKYSQKKLFHTLIRNFGYCGNYSPLTAMQISSGNPSMSSNSQVITLDTFKKFLETRQMESKSDGEIKMIIERHEPDQNLRTENLLSFEGFARYLMDKDNYAMTKTVCPTKMADLMNMNLPLSHYFIATSHNTYLTGHQLKGESSVELYSQVLLTGCRCVELDCWDGDDGYPIIYHGHTFTSKIPFRAVVDAINKSAFVASPYPVILSIENHCSMQQQIRMAQIFQTTFGDKLVTKFMFDIDYTDEPYLPTPEQLKYKIIVKNKKILVDVPVGISSPRSPYMRHQSNLSGRASSIISNSSAGSLNEDFEDSDYEDDDDIDNFDDKTYNIWGSSADDKYTRHSITSFTANVRKLEMEERSKKRSNQIARELSDLVTYVQAIKFRGLNPWIHYNLNQRNGTSTPSASGALSTSSTTIALTGNVTSTTTSSASSVVTTGSTIKIFTTGDTSAETESNTSGEQETLSSSASASTQYGSGNNVTTVHKKYPHANVNHPCYQCASINEANAKKICRKHPLAVIAHTETQLIRSYPAGLRIDSSNFNPVFFWSFGMQMVALNYQTEDLPMHINRAMFEQSNNYGYVCKPSIMWNRSHLMYRRFNPLEKEFDGLHTTQIVINIVNGQYLNQNNLLSSPYIEIEIIGIPGDCCKRKTKAIMRNAFNPIWNETFYFRVNFIDLAFIRFAVYDSDGGFMLAQRVMSIKSLRSGYRHVCLRSSTNLLLNMASLFIYSRIEEETIDSCYDESLMDRAKAATLSIMESKLLNNQLNSENDKGKRKTFFLTVYGVIPDEPYTILKVIQESSTKDVLQQALMKGGIPLENLNDFVLVEEVFPSWEKKDRAQPPKQRMLDANEKPLLSQAKWKGEGRFILKKIGDDPSSRAWLSTVRRVGAALDRQSDYMTTAFAKENLKISPSSGTSNSASDMALIENVEHFVVCVYNVSPDIPYAMLRVPLKATAQDVLAQALLKARRFDNPNNFVLLEEIQPNNANTPVHQRIMQQDENVYKTQANWKTLGRFIIQERQSTPSILRKVKSVDKGKGLSISRPSKFPIQSMLSDPTTSRIKAKSAESHSERKTKHNKYSPDQLDSYGYSSHHHHHHRSHYSEGETLSEEESKDDFLSTITRLKRMSMKKIKSWKN
| Type | Start | End | Length |
| CDS |
322 |
2878 |
2557 |
| CDS |
3582 |
3736 |
155 |
| CDS |
4076 |
4537 |
462 |
| CDS |
4619 |
4875 |
257 |
| CDS |
4935 |
5071 |
137 |
| CDS |
5198 |
5670 |
473 |
| CDS |
5805 |
5955 |
151 |
| CDS |
6351 |
6486 |
136 |
| CDS |
6563 |
6866 |
304 |
| CDS |
7215 |
7401 |
187 |
| CDS |
7477 |
7613 |
137 |
| CDS |
7715 |
7958 |
244 |
| CDS |
8301 |
8402 |
102 |
| CDS |
8700 |
8953 |
254 |
| CDS |
9436 |
9569 |
134 |
| CDS |
9702 |
9750 |
49 |
| CDS |
11129 |
11191 |
63 |
| intron |
2879 |
3581 |
703 |
| intron |
3737 |
4075 |
339 |
| intron |
4538 |
4618 |
81 |
| intron |
4876 |
4934 |
59 |
| intron |
5072 |
5197 |
126 |
| intron |
5671 |
5804 |
134 |
| intron |
5956 |
6350 |
395 |
| intron |
6487 |
6562 |
76 |
| intron |
6867 |
7214 |
348 |
| intron |
7402 |
7476 |
75 |
| intron |
7614 |
7714 |
101 |
| intron |
7959 |
8300 |
342 |
| intron |
8403 |
8699 |
297 |
| intron |
8954 |
9435 |
482 |
| intron |
9570 |
9701 |
132 |
| intron |
9751 |
11128 |
1378 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001868806 |
phospholipase c epsilon [Culex quinquefasciatus] gb|EDS27728.1| phospholipase c epsilon [Culex quinquefasciatus] |
0.0 |
| InterPro |
IPR015359 |
Phospholipase C, phosphoinositol-specific, EF-hand-like |
|
| InterPro |
IPR000909 |
Phospholipase C, phosphatidylinositol-specific , X domain |
|
| InterPro |
IPR011992 |
EF-hand-like domain |
|
| InterPro |
IPR008973 |
C2 calcium/lipid-binding domain, CaLB |
|
| InterPro |
IPR001192 |
Phosphoinositide phospholipase C |
|
| InterPro |
IPR001711 |
Phospholipase C, phosphatidylinositol-specific, Y domain |
|
| InterPro |
IPR017946 |
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain |
|
| InterPro |
IPR018029 |
C2 membrane targeting protein |
|
| InterPro |
IPR023578 |
Ras guanine nucleotide exchange factor, domain |
|
| InterPro |
IPR001895 |
Guanine-nucleotide dissociation stimulator CDC25 |
|
| InterPro |
IPR000008 |
C2 calcium-dependent membrane targeting |
|
| InterPro |
IPR000159 |
Ras-association |
|
| Gene Ontology(BP) |
GO:0007165 |
signal transduction |
|
| Gene Ontology(BP) |
GO:0007264 |
small GTPase mediated signal transduction |
|
| Gene Ontology(BP) |
GO:0035556 |
intracellular signal transduction |
|
| Gene Ontology(BP) |
GO:0006629 |
lipid metabolic process |
|
| Gene Ontology(CC) |
GO:0005622 |
intracellular |
|
| Gene Ontology(MF) |
GO:0008081 |
phosphoric diester hydrolase activity |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0004435 |
phosphatidylinositol phospholipase C activity |
|
| Gene Ontology(MF) |
GO:0005509 |
calcium ion binding |
|
| Gene Ontology(MF) |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
| Gene Ontology(MF) |
GO:0004629 |
phospholipase C activity |
|
| Pfam |
PF00788.18 |
Ras association (RalGDS/AF-6) domain |
6.1e-30 |
| Pfam |
PF00387.14 |
Phosphatidylinositol-specific phospholipase C, Y domain |
3.7e-33 |
| Pfam |
PF00617.14 |
RasGEF domain |
2.4e-11 |
| Pfam |
PF00388.14 |
Phosphatidylinositol-specific phospholipase C, X domain |
9.6e-63 |
| Pfam |
PF00168.25 |
C2 domain |
2.2e-11 |
| Pfam |
PF09279.6 |
Phosphoinositide-specific phospholipase C, efhand-like |
3.7e-11 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| A. gambiae |
AGAP002529 |
| D. plexippus |
DPOGS215111PA |
| B. mori |
BGIBMGA009604-TA |
| A. aegypti |
AAEL008246 |
| B. mori |
BGIBMGA009601-TA |
| N. vitripennis |
NV15424-PA |
| H. sapiens |
ENSP00000360431 |
| T. castaneum |
TC000206 |
| H. sapiens |
ENSP00000260766 |
| C. quinquefasciatus |
CPIJ018676 |
| H. sapiens |
ENSP00000360426 |
| M. musculus |
ENSMUSG00000024998 |
| H. melpomene |
HMEL014221-PA |
| P. vanderplanki |
Pv.07207 |
| P. vanderplanki |
Pv.12763 |
| S. invicta |
SI2.2.0_08734 |
| H. sapiens |
ENSP00000360438 |
| A. mellifera |
GB14007-PA |
| T. castaneum |
TC000207 |