MidgeBase gene description page [Pn.06903]
Outline
| Gene ID | Pn.06903 |
| Type | Protein coding gene |
| Scaffold | PnScaf6089 |
| Start | 40937 |
| End | 45426 |
| Direction | - |
Sequence
Transcript: 2805 (bp)
ATGGCTGGAATATTGAACGAGAGTGACGAGGAAATCAATGAATTGAACCAATTACTGGACGATGAAATTGACGGAATAGAAGGCTCAATCGGAAACTTCACTCTAAATGGCGATCGTGCACCACCTCCTCCACCGCCGCCGGAAACCGAGTGGTACCACGGTAGACTGGATCGGTTTAGTGCGGAACAGCGACTCAAAGCTGCCTACAAACTGGGAAGCTACTTAGTGAGGGAAAGTGATCGTAAGCCTGGCAGTTATGTGCTTTCGTATTTAGGCAAAACTGGAATAAATCACTTCCGCATTGCTGCTGTATGCGGCGATTTTTACATTGGCGGTCGCCAATTCTTCTCGTTAAGTGACTTGGTTGCATACTACTCATGCAACGACTTGCTGAAACGAGAACGACTCATACATGCCATCGCTCCGCCGGAACCAGTTTCTGACACGCGACGTGTCGTCGCAATACTGCCATACACGAAGATGCCGGACACCGATGAGCTGAGCTTCCAAAAGGGCGACATTTTCTTCGTGCACAATGACATGGGCGACGGCTGGATTTGGACGACGAAGCACCGCACCGGTGAGCAGGGCATGATCTTTGCCGAGCTCGTCGAGGACCTCGATCCGGGAATCGATCCCAACACGGTGTTCTCATGGTTCCATCCGAACTGCACCAAAAACGAGGCCGTCGACATGCTCGTGAAAAACGGACCCGGCTCCTTTCTCGTGCGACCAAGCGACAACTCGCCGGGCGACTATTCGCTCTTCTTTCACATCAACAATCAAATTCAGAGATTTCGCATCGAGAAAAAGGGAGTCCGCTACCTCATGGGCGGCCGGACTTTCGAGTGCTTGGACGCAGTCATAAACCGCTACCGCAAGGAGCAAATTGTCGAGGGCCATACTCTCCAAAATCCCGTCTCGAACGGCACCAGTCAACCGGAATTCCACCAACAGTCGGCGGTGTCGGCTGCGGCCGAGAAGATTTATGCAACGCTGCGCGAGTGTCGTGACCAAAACATGATCAAGAAGATTAAGGGCATCAAGCAGCAAGGGTACTTGATGAAGCGCTCCGACAAGACCGGCAAGTGGAAGCAACTGTATTTTGCTCTCATCAACGAGGGCACCGAGACGCATTTGTTCTTTTACGACAGCCCCAAGAAGACGAAACCGAAGGGCCTCATCGACCTGTCGTGCGCCTATCTGTACCAAGTGCACGAGTCGCTGTGGGAGCGATCGAACTGCTTCCAACTCGTGGAGCGAGCACTGCCATGTCTGGCGACCATTTCGCACTTGTGCGACAAAAACACTGAATCATATCAGGAATGGATTACGGTGCTCAAGCAGCACTGTCGTGCGCAGTTCAGCCGGGCTCAGTCGAAGCTGCCGCGTTTACGCGAGCTGCGCTGCTTGAACCTGCAAGTTCTCGAAGCGCACCGTATTCCATTCAAGCTCGTTCCGCACTGCTACATTACAATTGCTCTCAATCAAATCAAGATCGCGAAGACAAAGGTCAAGTCGACGCCCGACCCAATCTTCGAGGAGGAATTCGTGATCGACGACCTACCGATAGATATTGCCACGCTCAACATGACGCTCGTGTCGCGAGCGAAGAGAAACAAAGACTCGGACGTCGCCGAGCTGACCATTGACTTGTCGAGTCTCAAGAACGGCGCCGAAACGGAAAACTGGTACGATCTGAACGGCATCACGCCCATCGGCGAGTGGGGCTCGTTGCGCTTAAGGATAAGATATATGGACGATCTAGTCATGCCCGCCGAAGAATACTCACCGCTGCAGGAGCTCCTGCTCGAAAATGAATTTCACTCGGTGCGTGCACTCGCCGACTTGTGCCACTCGAATCGCATACCGTTGGCGTCGTCGTTGCTGAAAATCTTCCGGCACGAGAAGAAGGAGTGCGAACTGATGAAGTCCCTGTGCCAAGCTGAAATTGCTCGCGAGAGCGACACGAGTACGCTGTTCCGTGCGACCTCTCTGGCGACGACGCTCATGGACATTTACATGAGATCCGAGTGCGGGCTATTTCTGCAGTCAGCGTTATCCGATACGATACAGAAGCTATTGGAGAGCAAGCAAAGTGCAGAATTGAACCCAACGAAAATGGAAGTTAACGATGACGCTTGCACAAACGCTGAATTTCTTCTGCTAGTCCTCGATCAAATTACTCAATCCATATTCACGTCGATCGATGCATGTCCGCGCGGCGTTCGGCACATTTGCAATTGCTTGCAAAAGACGGTCGTTGCAAAGTGGCCGGGCGAGCGGCTCGTTCGAACGCGCGTTGTCTCCGGCTTCATTTTCCTTCGCTTGCTGTGTCCCGCTCTGCTTAACCCGCGACAATTTGGCCTCGTTCAAGAGCAACCGTCACCGATGGCGACACGATCTCTCATCATGGTTGCGAAATGCCTTCAAAATTTAGCCAATCTCATCGAATTTGGCGGCAAAGGCGAATTGCCATCGTTTCATGAAAGCTATATGGAAGTCGTCAATCCATTCATACTGAAGAATAAAGAGCGAATGATTGTTTTCCTTGATCAACTCTCGAGCGTTAGCGATCCGTTTGTTCCACAGGGCGGGATAGACATTTCCGGAAACTCAATTGCCAACAACAGTTCCGATACAGGACGGGAACTGGCAACCTTGCATCACATTTGCGTGTCACATCTACCAGAACTCCAAAACATGTCGAAAGTAAACATGTCCATCAAGAAATTGGTGACGGTGACTGAAATGCTGTCGAAGCATAAACTGAAGTATTTGGAAATGATCAATGAAAGTGCACGT
Protein: 935 (aa)
MAGILNESDEEINELNQLLDDEIDGIEGSIGNFTLNGDRAPPPPPPPETEWYHGRLDRFSAEQRLKAAYKLGSYLVRESDRKPGSYVLSYLGKTGINHFRIAAVCGDFYIGGRQFFSLSDLVAYYSCNDLLKRERLIHAIAPPEPVSDTRRVVAILPYTKMPDTDELSFQKGDIFFVHNDMGDGWIWTTKHRTGEQGMIFAELVEDLDPGIDPNTVFSWFHPNCTKNEAVDMLVKNGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLQNPVSNGTSQPEFHQQSAVSAAAEKIYATLRECRDQNMIKKIKGIKQQGYLMKRSDKTGKWKQLYFALINEGTETHLFFYDSPKKTKPKGLIDLSCAYLYQVHESLWERSNCFQLVERALPCLATISHLCDKNTESYQEWITVLKQHCRAQFSRAQSKLPRLRELRCLNLQVLEAHRIPFKLVPHCYITIALNQIKIAKTKVKSTPDPIFEEEFVIDDLPIDIATLNMTLVSRAKRNKDSDVAELTIDLSSLKNGAETENWYDLNGITPIGEWGSLRLRIRYMDDLVMPAEEYSPLQELLLENEFHSVRALADLCHSNRIPLASSLLKIFRHEKKECELMKSLCQAEIARESDTSTLFRATSLATTLMDIYMRSECGLFLQSALSDTIQKLLESKQSAELNPTKMEVNDDACTNAEFLLLVLDQITQSIFTSIDACPRGVRHICNCLQKTVVAKWPGERLVRTRVVSGFIFLRLLCPALLNPRQFGLVQEQPSPMATRSLIMVAKCLQNLANLIEFGGKGELPSFHESYMEVVNPFILKNKERMIVFLDQLSSVSDPFVPQGGIDISGNSIANNSSDTGRELATLHHICVSHLPELQNMSKVNMSIKKLVTVTEMLSKHKLKYLEMINESAR
| Type | Start | End | Length |
| CDS |
40940 |
41100 |
161 |
| CDS |
41160 |
41316 |
157 |
| CDS |
41648 |
41668 |
21 |
| CDS |
41988 |
44154 |
2167 |
| CDS |
44494 |
44566 |
73 |
| CDS |
44828 |
44944 |
117 |
| CDS |
45318 |
45426 |
109 |
| intron |
41101 |
41159 |
59 |
| intron |
41317 |
41647 |
331 |
| intron |
41669 |
41987 |
319 |
| intron |
44155 |
44493 |
339 |
| intron |
44567 |
44827 |
261 |
| intron |
44945 |
45317 |
373 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001656445 |
ras gtpase activating protein [Aedes aegypti] gb|EAT48547.1| ras gtpase activating protein [Aedes aegypti] |
0.0 |
| InterPro |
IPR023152 |
Ras GTPase-activating protein, conserved site |
|
| InterPro |
IPR001452 |
Src homology-3 domain |
|
| InterPro |
IPR000980 |
SH2 domain |
|
| InterPro |
IPR001936 |
Ras GTPase-activating protein |
|
| InterPro |
IPR011993 |
Pleckstrin homology-like domain |
|
| InterPro |
IPR008973 |
C2 calcium/lipid-binding domain, CaLB |
|
| InterPro |
IPR000008 |
C2 calcium-dependent membrane targeting |
|
| InterPro |
IPR008936 |
Rho GTPase activation protein |
|
| InterPro |
IPR001849 |
Pleckstrin homology domain |
|
| Gene Ontology(BP) |
GO:0007165 |
signal transduction |
|
| Gene Ontology(BP) |
GO:0051056 |
regulation of small GTPase mediated signal transduction |
|
| Gene Ontology(CC) |
GO:0005622 |
intracellular |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0005543 |
phospholipid binding |
|
| Gene Ontology(MF) |
GO:0005096 |
GTPase activator activity |
|
| Pfam |
PF07653.12 |
Variant SH3 domain |
0.00023 |
| Pfam |
PF00017.19 |
SH2 domain |
6.7e-35 |
| Pfam |
PF00169.24 |
PH domain |
5.2e-10 |
| Pfam |
PF00616.14 |
GTPase-activator protein for Ras-like GTPase |
2.9e-39 |
| Pfam |
PF00018.23 |
SH3 domain |
2.2e-09 |
| Pfam |
PF00168.25 |
C2 domain |
0.00089 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| D. melanogaster |
FBgn0003969 |
| M. musculus |
ENSMUSG00000021549 |
| T. castaneum |
TC016087 |
| A. mellifera |
GB11775-PA |
| B. mori |
BGIBMGA001560-TA |
| H. sapiens |
ENSP00000422008 |
| A. gambiae |
AGAP002729 |
| A. aegypti |
AAEL000450 |
| D. plexippus |
DPOGS204820PA |
| C. quinquefasciatus |
CPIJ002855 |
| S. invicta |
SI2.2.0_01703 |
| H. sapiens |
ENSP00000420905 |
| P. humanus |
PHUM244140-PA |
| N. vitripennis |
NV16747-PA |
| H. melpomene |
HMEL016505-PA |
| H. sapiens |
ENSP00000274376 |
| H. sapiens |
ENSP00000423395 |
| H. sapiens |
ENSP00000411221 |
| P. vanderplanki |
Pv.14067 |