MidgeBase gene description page [Pn.06546]
Outline
| Gene ID | Pn.06546 |
| Type | Protein coding gene |
| Scaffold | PnScaf5796 |
| Start | 4382 |
| End | 14168 |
| Direction | + |
Sequence
Transcript: 2892 (bp)
ATGGGATCAACGACATCGAAGTCAAAGTCGACGACAATTTCGCCGCTTGTGACGACAAAGCGCGCCTCGAAGCGCATCCTCAAGCGAAACTCCGCCATTTATCCGACGACGCCGTCGCAGAACGTCACCAACGGCGGCAGCGTCACCGACACCAACGCGACGTCGGACGGCGTCGAAAACAACAACAACAATAGCAGCCACACGCCGTCGCAAGAGGACAGAGAGGTGGTCGTGATAAGAAACAAAAGCCACGCTCTAAACTCGAACGGCGACGTCTCGTCCACGCCGACGACGCCGAAGAACGCCAAAAAGGAGAAGAAGAAGAAAAAGGGCGGCGACGGTGGCGGCGGCGGCGTGAGTGGCGACGAGTCCGCACCGAGCTACCACCAGACCAACGTTTGCTACTACAAAGTCGAGAACGGGACGTTTCTGAAGCTGCCGAACGACACGAAGCACAAAAGCAACGACGGCTGCTACGTGAAGCTCTCGAACGGCAGCTTCCGTCATCTGATGGTGCCGGACGGCGCCGGCAGCCGGCCCGAAGTCAACTTCAAGCCCGACGGCGGCCCCGTGAACAAACGCGACGCGCGCCAGTCGATGCCGGTGCCGCCGAAAAGTAGCGCCATGGCAGCAGCCGGCGGAGGAGCGAACGAGGAGAGGAAGGAGGAGAAGAACCGAAAGGTCATGGTCACGATGATCGATGGCGGTTTGCCGGTGGTCGCCGTCAGCAAGCGCGACAAGACCGCCAATCTCGCCAAGAAGGAGAAGATCAAGAAAAAAGAAAAGAAGAAGAAAATGAGTGAATTCGACCGGACCGAGAACATAAGGCGATCGATTCGACGCCCGAAAAAGTCGCCAGCCCCGCTTCCGCCGGTGGACTCGCAGCGGCCCTCGCCCAGCGAGGATGTCTCGGCCATCATCAAGCGACTGCTGAACACGCGCCGAGACTTCGTGGCGACCTCGCCCGCAACTGTCGCTTCCCCACCGCAGCAACAGTCGCAGCAACAGTCACAGATGCCAAAGATCGTCGCCAGCACTCCGAAAAGCGAAAACGACTCGGCGCACAGCGCTCTGCTCGCAATTCAGCGGCACATCAATCAGATCGAGTTCAACCAGAAGATAAGTGAGCCGCAGCCGGCGCCATCGACGGCGGTGCCGCCAGCTGCGCGAAAAACGCGCTACGACGAAATGGAGTCGCTGCTCAACACGGGCATCAGCGACCTCGCGACAAACAAGCACGACACCGACGACGAGAGCGACGCGATTGAGTTTCAGCGCGGCGGCGGCACGCGCAGCTCGGTTCAGGGCGTTCCCGGTGCATCGGCCGAGGCACGCAAGGTGCTGAGGATGCCGCGACCCGTGGCACGCACTGCCAGCGACACAAAGCAACACGAGCTGCTGCGCAACATCTTCAAGCACTCGACGCCCACGCCGTCGAGGGAGAAGAAGGAGAGCGTTGATGATCGCACGAGCAAGGGCTCGCCGAACATGCAGATGCGCGTGAGCAACAGTCACAACCGGTGGCGTCCGGGCGAGGAGCAACAGTCGGGCGCGAACCACACGAGATGGCGTCCGGCAGAGGAACAAATCGGCAAGTATCGACTGCTCAAGACAATCGGCAAGGGAAACTTCGCCAAGGTGAAACTCGCCAAGCACGTGCCAACCGGCAAGGAGGTGGCCATCAAGATCATCGACAAGACACAACTCAATCCCACCAGCTTGCAGAAGCTCTTTCGCGAGGTGCGCATCATGAAGATGCTCGACCACCCCAACATCGTGAAGCTCTTTCAGGTCATACAGACGGACAAGACGCTCTACCTCGTCATGGAGTACGCGTCCGGCGGCGAGGTCTTTGACTATCTCGTCATGCACGGCCGCATGAAGGAGAAGGAGGCGCGCGCCAAGTTCCGACAAATCGTCTCGGCCGTACAGTATTTGCATCAGAAGCGCATCATTCATCGTGATCTTAAGGCAGAGAACCTTCTGCTCGACTCAGAAATGAACATAAAGATCGCCGACTTTGGCTTTAGTAATGAATTTACTCCCGGCAACAAGCTGGATACCTTCTGCGGGAGTCCGCCCTACGCTGCGCCCGAGCTCTTTCAGGGCAGAAAGTATGATGGTCCCGAGGTTGACGTGTGGTCACTCGGCGTGATTCTTTATACGCTGGTGAGCGGCTCGCTTCCATTCGACGGTACAACGTTACGTGAGCTGCGTGAACGCGTGTTACGCGGCAAGTATCGCATACCATTCTACATATCCACCGACTGCGAAAACTTACTGAGGAAGTTCCTCGTGCTGAACCCGGCGAAGCGTGCGAGCTTAGAGCAAATTATGAAGGATAAGTGGATGAACATGGGCTATGAGGATGACGAGCTGAAACCGTATGTCGAGCCACAGCCCGATCTGAACGATCAGAAACGGATAGAGTGCTTGGTGGCGCTGGGCTACAAGCGAGAGGACATTGAGGCGTCGCTATCCCAAACACGATACGATGATGTGCATGCAACTTATTTACTAATTAGTCGTAAAAATACAGATCCGGAGTCGGACGGCTCCCGATCAGGTTCATCTCTTTCGTTACGTAACCTAACGGGCGATGCTGCGCAGCAGGGCGCAAACAGTCAAGTGCAGTCGCCGACTCATCGTCGCGTCCATCGCAGCATCTCGGCGACCAGTACGAACCCGTCGCGACGCGCATCATCGGGCGGTGAGACATTGCGTGAGTTTCGATGGGCGCGCAGAAATTTGAAATTTTCTAATTTTATTCTTCTTGCGGATTCTTTTAGGAACGGCACAAGCAGTTCCGGCAACAAACGCCACCAACGGCACCACATCGACAGCGGCATCAAATGCCTCGTCCTCGTCGGCGGCGCCCGAGCGATCAACCAT
Protein: 964 (aa)
MGSTTSKSKSTTISPLVTTKRASKRILKRNSAIYPTTPSQNVTNGGSVTDTNATSDGVENNNNNSSHTPSQEDREVVVIRNKSHALNSNGDVSSTPTTPKNAKKEKKKKKGGDGGGGGVSGDESAPSYHQTNVCYYKVENGTFLKLPNDTKHKSNDGCYVKLSNGSFRHLMVPDGAGSRPEVNFKPDGGPVNKRDARQSMPVPPKSSAMAAAGGGANEERKEEKNRKVMVTMIDGGLPVVAVSKRDKTANLAKKEKIKKKEKKKKMSEFDRTENIRRSIRRPKKSPAPLPPVDSQRPSPSEDVSAIIKRLLNTRRDFVATSPATVASPPQQQSQQQSQMPKIVASTPKSENDSAHSALLAIQRHINQIEFNQKISEPQPAPSTAVPPAARKTRYDEMESLLNTGISDLATNKHDTDDESDAIEFQRGGGTRSSVQGVPGASAEARKVLRMPRPVARTASDTKQHELLRNIFKHSTPTPSREKKESVDDRTSKGSPNMQMRVSNSHNRWRPGEEQQSGANHTRWRPAEEQIGKYRLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPTSLQKLFREVRIMKMLDHPNIVKLFQVIQTDKTLYLVMEYASGGEVFDYLVMHGRMKEKEARAKFRQIVSAVQYLHQKRIIHRDLKAENLLLDSEMNIKIADFGFSNEFTPGNKLDTFCGSPPYAAPELFQGRKYDGPEVDVWSLGVILYTLVSGSLPFDGTTLRELRERVLRGKYRIPFYISTDCENLLRKFLVLNPAKRASLEQIMKDKWMNMGYEDDELKPYVEPQPDLNDQKRIECLVALGYKREDIEASLSQTRYDDVHATYLLISRKNTDPESDGSRSGSSLSLRNLTGDAAQQGANSQVQSPTHRRVHRSISATSTNPSRRASSGGETLREFRWARRNLKFSNFILLADSFRNGTSSSGNKRHQRHHIDSGIKCLVLVGGARAINH
| Type | Start | End | Length |
| CDS |
4382 |
5155 |
774 |
| CDS |
6695 |
7396 |
702 |
| CDS |
8098 |
8582 |
485 |
| CDS |
8859 |
9034 |
176 |
| CDS |
9099 |
9301 |
203 |
| CDS |
9358 |
9445 |
88 |
| CDS |
13406 |
13518 |
113 |
| CDS |
13741 |
14091 |
351 |
| intron |
5156 |
6694 |
1539 |
| intron |
7397 |
8097 |
701 |
| intron |
8583 |
8858 |
276 |
| intron |
9035 |
9098 |
64 |
| intron |
9302 |
9357 |
56 |
| intron |
9446 |
13405 |
3960 |
| intron |
13519 |
13740 |
222 |
| intron |
14092 |
14165 |
74 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001648114 |
map/microtubule affinity-regulating kinase 2,4 [Aedes aegypti] gb|EAT44694.1| map/microtubule affinity-regulating kinase 2,4 [Aedes aegypti] |
0.0 |
| InterPro |
IPR015940 |
Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote |
|
| InterPro |
IPR017441 |
Protein kinase, ATP binding site |
|
| InterPro |
IPR000719 |
Protein kinase, catalytic domain |
|
| InterPro |
IPR002290 |
Serine/threonine- / dual-specificity protein kinase, catalytic domain |
|
| InterPro |
IPR020635 |
Tyrosine-protein kinase, catalytic domain |
|
| InterPro |
IPR011009 |
Protein kinase-like domain |
|
| InterPro |
IPR008271 |
Serine/threonine-protein kinase, active site |
|
| Gene Ontology(BP) |
GO:0006468 |
protein phosphorylation |
|
| Gene Ontology(MF) |
GO:0004713 |
protein tyrosine kinase activity |
|
| Gene Ontology(MF) |
GO:0004674 |
protein serine/threonine kinase activity |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0004672 |
protein kinase activity |
|
| Gene Ontology(MF) |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
|
| Pfam |
PF00069.20 |
Protein kinase domain |
4.6e-79 |
| Pfam |
PF01171.15 |
PP-loop family |
0.0048 |
| Pfam |
PF06293.9 |
Lipopolysaccharide kinase (Kdo/WaaP) family |
0.0026 |
| Pfam |
PF01636.18 |
Phosphotransferase enzyme family |
0.092 |
| Pfam |
PF00627.26 |
UBA/TS-N domain |
0.16 |
| Pfam |
PF07714.12 |
Protein tyrosine kinase |
9e-47 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
| Gene ID |
| Pn.06356 |
| Pn.08830 |
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000300843 |
| H. sapiens |
ENSP00000425765 |
| H. sapiens |
ENSP00000423452 |
| H. sapiens |
ENSP00000421075 |
| H. sapiens |
ENSP00000386017 |
| H. sapiens |
ENSP00000385751 |
| A. gambiae |
AGAP012064 |
| M. musculus |
ENSMUSG00000030397 |
| A. mellifera |
GB15281-PA |
| H. sapiens |
ENSP00000367040 |
| H. sapiens |
ENSP00000367041 |
| B. mori |
BGIBMGA000136-TA |
| P. vanderplanki |
Pv.10790 |
| H. sapiens |
ENSP00000303698 |
| C. quinquefasciatus |
CPIJ010275 |
| N. vitripennis |
NV50087-PA |
| H. sapiens |
ENSP00000423974 |
| H. sapiens |
ENSP00000451623 |
| H. sapiens |
ENSP00000326632 |
| D. melanogaster |
FBgn0260934 |
| D. plexippus |
DPOGS205505PA |
| S. invicta |
SI2.2.0_11304 |
| A. aegypti |
AAEL003953 |
| P. vanderplanki |
Pv.03665 |
| P. humanus |
PHUM509230-PA |
| H. sapiens |
ENSP00000402104 |
| H. sapiens |
ENSP00000408092 |
| M. musculus |
ENSMUSG00000026620 |
| H. sapiens |
ENSP00000389184 |
| H. sapiens |
ENSP00000216288 |
| H. melpomene |
HMEL011289-PA |
| H. sapiens |
ENSP00000386128 |
| H. sapiens |
ENSP00000262891 |
| H. sapiens |
ENSP00000294247 |
| H. sapiens |
ENSP00000411397 |
| H. sapiens |
ENSP00000355091 |
| H. sapiens |
ENSP00000335347 |
| H. sapiens |
ENSP00000355885 |
| M. musculus |
ENSMUSG00000007411 |
| T. castaneum |
TC002567 |
| H. sapiens |
ENSP00000415494 |
| H. sapiens |
ENSP00000355884 |
| H. sapiens |
ENSP00000450772 |
| H. sapiens |
ENSP00000450460 |