MidgeBase gene description page [Pn.04947]
Outline
| Gene ID | Pn.04947 |
| Type | Protein coding gene |
| Scaffold | PnScaf4249 |
| Start | 30494 |
| End | 32994 |
| Direction | + |
Sequence
Transcript: 1443 (bp)
ATGGCAGAGAAAGCTGATATTGCATTGATTGGATTGGCCGTCATGGGCCAAAACTTAATCCTCAACATGGACTCGAAAGGCTTCAAAGTTTGTGCATTTAACCGCACGGTTGATAAGGTCAAGCATTTTTTGGAAAATGAGGCAAAGGGAACAAACATCATCGGCGCTACCTCAATGGAAGACATGGTCAGCAAGTTGAAGAGTCCACGACGTGTTATGCTCCTGGTCAAAGCTGGTAGTGCCGTTGACGATTTCATCAAGCAGCTCACGCCGTTGCTTTCACCGGGTGACATCATCATCGATGGCGGCAACTCCGAATATCAAGACACAGCCAGACGCGTCGAGGAGTGCAAGAAACACAAGCTCTTGTTTGTCGGCTCAGGCGTGAGCGGCGGCGAGGAGGGCGCCCGCTACGGACCTTCACTCATGCCCGGCGGAAACCCCGAGGCCTGGCCACACATCAAGGACATCTTCCAGTCGATCTGTGCACGCGCCGACAACGAGCCGTGCTGCGAGTGGGTCGGTGAAGGTGGCAGCGGGCACTTTGTCAAAATGGTGCACAACGGCATCGAGTACGGCGACATGCAGTTGATTTGCGAGGCCTACGATCTCATGAAGGCGATGGGCATGAGCCAGAAGGAAATGGCCGACGCCTTCACCGAGTGGAACAAGGGAGAGCTCGACTCCTTCCTAATCGAGATCACGAGCAGCATTCTCAACTACAAGGATAAGGACGGTTATTTGCTGGAACGCATTCGCGATACGGCCGGCCAGAAGGGCACGGGCAAGTGGACTGCAATCGCCGCCCTTCAGTACGGAGTGCCGGTCACTCTCATCGGAGAGGCCGTTTTCTCGCGCTGCCTTTCGGCACTCAAGAACGAGCGCGTTGCTGCCAGCAAAATGCTGCATGGACCGGACGGCAAGCCGATGGTGGCCAACAAGGCTGAGTTCCTCAACCACATCAAGAATGCTCTGTATTGCGCCAAGATCGTCTCGTACGCTCAGGGCTTCATGCTGATGCGCGAGGCAGCCAAGGAGAACGGCTGGCACTTGAACTACGGCGGCATCGCATTGATGTGGCGCGGAGGCTGCATCATTCGAAGCGTTTTCTTAGGAAATATCAAAGAGGCATTTACTCGCAACCCGCAGCTCTCGAACTTGCTGCTCGACGACTTCTTCAAGACTGCAATCACTAAGAACCAGCACTCGTGGAGGCAGGTTGTTTCGAGCGCAACTCTCTGGGGCATTCCGGTTCCGGCTCTTTCGGCTGCTCTTTCCTTCTTCGATGGCTATCGCTCTGAGCGACTTCCAGCCAATCTCTTGCAAGCCCAACGCGACTTTTTCGGTGCTCACACCTACGAGTTGCTGGGACAAGAGGGCAAATTCGTTCACACAAATTGGACCGGCACTGGCGGAAATGTCAGCTCCTCGTCATACAACGCA
Protein: 481 (aa)
MAEKADIALIGLAVMGQNLILNMDSKGFKVCAFNRTVDKVKHFLENEAKGTNIIGATSMEDMVSKLKSPRRVMLLVKAGSAVDDFIKQLTPLLSPGDIIIDGGNSEYQDTARRVEECKKHKLLFVGSGVSGGEEGARYGPSLMPGGNPEAWPHIKDIFQSICARADNEPCCEWVGEGGSGHFVKMVHNGIEYGDMQLICEAYDLMKAMGMSQKEMADAFTEWNKGELDSFLIEITSSILNYKDKDGYLLERIRDTAGQKGTGKWTAIAALQYGVPVTLIGEAVFSRCLSALKNERVAASKMLHGPDGKPMVANKAEFLNHIKNALYCAKIVSYAQGFMLMREAAKENGWHLNYGGIALMWRGGCIIRSVFLGNIKEAFTRNPQLSNLLLDDFFKTAITKNQHSWRQVVSSATLWGIPVPALSAALSFFDGYRSERLPANLLQAQRDFFGAHTYELLGQEGKFVHTNWTGTGGNVSSSSYNA
| Type | Start | End | Length |
| CDS |
30494 |
30501 |
8 |
| CDS |
30632 |
30740 |
109 |
| CDS |
31093 |
31207 |
115 |
| CDS |
31708 |
31994 |
287 |
| CDS |
32068 |
32991 |
924 |
| intron |
30502 |
30631 |
130 |
| intron |
30741 |
31092 |
352 |
| intron |
31208 |
31707 |
500 |
| intron |
31995 |
32067 |
73 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
P41570 |
RecName: Full=6-phosphogluconate dehydrogenase, decarboxylating gb|AAB29396.1| 6-phosphogluconate dehydrogenase [Ceratitis capitata] |
0.0 |
| InterPro |
IPR006115 |
6-phosphogluconate dehydrogenase, NADP-binding |
|
| InterPro |
IPR008927 |
6-phosphogluconate dehydrogenase, C-terminal-like |
|
| InterPro |
IPR013328 |
Dehydrogenase, multihelical |
|
| InterPro |
IPR006114 |
6-phosphogluconate dehydrogenase, C-terminal |
|
| InterPro |
IPR016040 |
NAD(P)-binding domain |
|
| InterPro |
IPR012284 |
Fibritin/6-phosphogluconate dehydrogenase, C-terminal extension |
|
| InterPro |
IPR006113 |
6-phosphogluconate dehydrogenase, decarboxylating |
|
| InterPro |
IPR006184 |
6-phosphogluconate-binding site |
|
| Gene Ontology(BP) |
GO:0006098 |
pentose-phosphate shunt |
|
| Gene Ontology(BP) |
GO:0055114 |
oxidation-reduction process |
|
| Gene Ontology(MF) |
GO:0050661 |
NADP binding |
|
| Gene Ontology(MF) |
GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
|
| Gene Ontology(MF) |
GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
|
| Gene Ontology(MF) |
GO:0000166 |
nucleotide binding |
|
| Gene Ontology(MF) |
GO:0050662 |
coenzyme binding |
|
| Gene Ontology(MF) |
GO:0016491 |
oxidoreductase activity |
|
| Pfam |
PF03807.12 |
NADP oxidoreductase coenzyme F420-dependent |
0.019 |
| Pfam |
PF00393.14 |
6-phosphogluconate dehydrogenase, C-terminal domain |
3.1e-134 |
| Pfam |
PF01488.15 |
Shikimate / quinate 5-dehydrogenase |
0.0028 |
| Pfam |
PF03446.10 |
NAD binding domain of 6-phosphogluconate dehydrogenase |
1.6e-50 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| A. aegypti |
AAEL005931 |
| B. mori |
BGIBMGA012298-TA |
| P. vanderplanki |
Pv.10218 |
| A. mellifera |
GB12949-PA |
| H. melpomene |
HMEL016639-PA |
| H. sapiens |
ENSP00000437822 |
| D. plexippus |
DPOGS203400PA |
| T. castaneum |
TC010448 |
| H. sapiens |
ENSP00000270776 |
| C. quinquefasciatus |
CPIJ001316 |
| D. melanogaster |
FBgn0004654 |
| H. sapiens |
ENSP00000442285 |
| M. musculus |
ENSMUSG00000028961 |
| N. vitripennis |
NV16426-PA |
| A. gambiae |
AGAP004197 |
| H. sapiens |
ENSP00000467362 |