MidgeBase gene description page [Pn.04917]
Outline
| Gene ID | Pn.04917 |
| Type | Protein coding gene |
| Scaffold | PnScaf4227 |
| Start | 6118 |
| End | 11095 |
| Direction | - |
Sequence
Transcript: 2310 (bp)
ATGGGACTTTCAACACAAGGAAAAAATATTCACGATGTAATTGCTTCGCGACAAGATTCCGAGATACGTTTGATAGAAGTGATGCGCAAATGTTTGTTGCTTAAAGTGAAATGTGATCGTGATTATGCATGTTCTATTCAAAATGTTTCACTTGTTGGTATGAAAATCGATCGGATAGATGATCTAAATGGAAATCAAATGTTTAGAACATGGAAGCGTTTTATGGAAGAATTAGAAAATCATTCGAAATCTATTCGGAAAAGGATGGAATGCCTTGAAAGCATATGCATCGATCGAATTTCAAATGTTTTAGCTGAAAAAAGAAGAATAAAGAAACAGTGTCAAGATGATCACGACAAAATATCGTCTAGACTTCTCCAGCTAACTGACGAAGTTGCAAAGAAGAAGACTGAATATCATAAGCAACTAGAATACTACAAGCAGATGAGATTACGATTCGAAGAGCATTATATCAAAGCTGGACGATCGGGGAAGAAATTAGATGATGTTCGTGAAAAATACCAAAAGGCTTGTAGAAAGCTGCATTTGATTCATAACGAATACGTCCTACTAATACATGAAGCAATTGAAGTTGAAAAAGATTATCGTTCGGATTTGTTTCCTGCGTTACTATCGAATCAAGATGTCTTGCAAAAGGACCTTAACGAAACCTGGAAAAGTATTTTAGAGGACGTTTCCAAACTACTCGATATATCAGCAACTGAAGAATTTTCAAAAATTCAAGAACAAATGAGTAACGGCCTGAAAAATTTAAAATTACTGTCTATCGATGACTTTAATGATGTGCTAGGAAAACATGTAGCATCTCCAATGATATTCCGCTTCGACGAAAGTTTGATAAATGGAAATAACGTTGGAAAACTTCTCCCAAATCAATTGACGGTTGATAATTTAACAATCGATTGGCTGAAACAGAAAATAATCGATTTTGAGCAGTCGATAAAAGACTGTCAAGAGGAGCAGCTAAAGCTTAAAGGAAATGATAATTTAATCGTCATCGATTTAAAGTTGAGGTCCTTGAAAAACGAAGAGAGGCAGTTAGGAAGAGTTTTGGAAATGATAAAATCATCTTTAAATGAAGTCTCACTGAATGAATTGCCAAGTGGTTGTGATGACGATGACTTGTCCCCAGCAGTAGAGAGTGAGGAAAAGTATAGGCAAAGCTCTCTTACAGTATCGACCAGCCGCCCATTGTACGAAGAGGAGTGGTTTCACGGAGTTCTTCCGCGTGAAGAAGTGGTTCGTCTCCTTAGAAATGATGGTGATTTTTTGGTGCGTGAAACGACGCGAAATGACGAAACTCAGATCGTCTTGAGTGTTTGTTGGAATGGGCATAAACATTTCATTGTACAAACAACAGCAGATGGTCATTATCGTTTTGAAGGTCCCGCATTTCCAAATATACAAGAACTTATTCTTCATCAATATCAATCTAATTCAGTAGTTACGAATCGAAGTGGAGCAATACTCAAAAACCCCATATTTAAAGAAAAATGGGAGCTGTCAAACGACGATGTTTTGCTCGTAGAAAAAATTGGAAGAGGCAATTTTGGTGATGTTTATAAAGCTAAATTGAAAAATACAAAGCAAGATGTTGCAGTTAAAACATGCAAAATGACATTGCCGGAGGAACAGAAGAAAAAGTTTCTACAAGAAGGGCGAATTCTGAAACAATATGATCATCCAAATATTGTAAAGCTAATTGGAATATGCGTTCAAAAGCAACCGATTATGATTGTAATGGAACTCGTAGAAGGCGGCTCCCTTTTGATGTTTCTTAGAAAAAACGCGCAAGTTTTAGAGCTTAAACAAATGCTTCGAATGTGCAGTGATGTTGCTGCAGGCATGCGGTATTTAGAATCAAAAAATTGTATCCACCGTGACTTAGCTGCCAGAAATTGCTTAATAGGATCAGAAAAAATTGTTAAAATTTCTGATTTCGGCATGTCAAGAGAAGAAGAAGAATACATTGTCTCTGACGGCATGAAGCAAATTCCGATTAAGTGGACAGCGCCCGAAGCTCTCAATTGGGGAAAATATAACTCGTTAACTGATGTATGGAGTTATGGAATCTTGATGTTTGAAATTTTTTCAAAAGGTGCAACACCCTATTCTGGATTTTCAAACTCAAAAGCTAGAGAGAAAATAGAGGAAGGATATAGGTTGCCAGCACCAGAGGGAACACCGATCAAAGTTTATGATCTCATGCTCAAATGTTGGAGTGAAAATCCAGAAGATCGACCGCACTTTAATGATATTTGCAATGAAATTTTACATCTTTTAAACCAA
Protein: 770 (aa)
MGLSTQGKNIHDVIASRQDSEIRLIEVMRKCLLLKVKCDRDYACSIQNVSLVGMKIDRIDDLNGNQMFRTWKRFMEELENHSKSIRKRMECLESICIDRISNVLAEKRRIKKQCQDDHDKISSRLLQLTDEVAKKKTEYHKQLEYYKQMRLRFEEHYIKAGRSGKKLDDVREKYQKACRKLHLIHNEYVLLIHEAIEVEKDYRSDLFPALLSNQDVLQKDLNETWKSILEDVSKLLDISATEEFSKIQEQMSNGLKNLKLLSIDDFNDVLGKHVASPMIFRFDESLINGNNVGKLLPNQLTVDNLTIDWLKQKIIDFEQSIKDCQEEQLKLKGNDNLIVIDLKLRSLKNEERQLGRVLEMIKSSLNEVSLNELPSGCDDDDLSPAVESEEKYRQSSLTVSTSRPLYEEEWFHGVLPREEVVRLLRNDGDFLVRETTRNDETQIVLSVCWNGHKHFIVQTTADGHYRFEGPAFPNIQELILHQYQSNSVVTNRSGAILKNPIFKEKWELSNDDVLLVEKIGRGNFGDVYKAKLKNTKQDVAVKTCKMTLPEEQKKKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVEGGSLLMFLRKNAQVLELKQMLRMCSDVAAGMRYLESKNCIHRDLAARNCLIGSEKIVKISDFGMSREEEEYIVSDGMKQIPIKWTAPEALNWGKYNSLTDVWSYGILMFEIFSKGATPYSGFSNSKAREKIEEGYRLPAPEGTPIKVYDLMLKCWSENPEDRPHFNDICNEILHLLNQ
| Type | Start | End | Length |
| CDS |
6121 |
6437 |
317 |
| CDS |
6620 |
6748 |
129 |
| CDS |
6805 |
6901 |
97 |
| CDS |
6970 |
7350 |
381 |
| CDS |
7412 |
7609 |
198 |
| CDS |
8620 |
8779 |
160 |
| CDS |
8872 |
9225 |
354 |
| CDS |
9351 |
9546 |
196 |
| CDS |
9996 |
10092 |
97 |
| CDS |
10149 |
10339 |
191 |
| CDS |
10906 |
11095 |
190 |
| intron |
6438 |
6619 |
182 |
| intron |
6749 |
6804 |
56 |
| intron |
6902 |
6969 |
68 |
| intron |
7351 |
7411 |
61 |
| intron |
7610 |
8619 |
1010 |
| intron |
8780 |
8871 |
92 |
| intron |
9226 |
9350 |
125 |
| intron |
9547 |
9995 |
449 |
| intron |
10093 |
10148 |
56 |
| intron |
10340 |
10905 |
566 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_003436548 |
AGAP003651-PB [Anopheles gambiae str. PEST] gb|EGK97090.1| AGAP003651-PB [Anopheles gambiae str. PEST] |
0.0 |
| InterPro |
IPR017441 |
Protein kinase, ATP binding site |
|
| InterPro |
IPR002290 |
Serine/threonine- / dual-specificity protein kinase, catalytic domain |
|
| InterPro |
IPR001245 |
Serine-threonine/tyrosine-protein kinase catalytic domain |
|
| InterPro |
IPR001060 |
Fps/Fes/Fer/CIP4 homology |
|
| InterPro |
IPR011009 |
Protein kinase-like domain |
|
| InterPro |
IPR000980 |
SH2 domain |
|
| InterPro |
IPR000719 |
Protein kinase, catalytic domain |
|
| InterPro |
IPR008266 |
Tyrosine-protein kinase, active site |
|
| InterPro |
IPR020635 |
Tyrosine-protein kinase, catalytic domain |
|
| Gene Ontology(BP) |
GO:0006468 |
protein phosphorylation |
|
| Gene Ontology(MF) |
GO:0004713 |
protein tyrosine kinase activity |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0004672 |
protein kinase activity |
|
| Gene Ontology(MF) |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
|
| Pfam |
PF00069.20 |
Protein kinase domain |
3.6e-52 |
| Pfam |
PF00611.18 |
Fes/CIP4, and EFC/F-BAR homology domain |
5.5e-05 |
| Pfam |
PF00017.19 |
SH2 domain |
3.5e-16 |
| Pfam |
PF10186.4 |
UV radiation resistance protein and autophagy-related subunit 14 |
0.085 |
| Pfam |
PF07714.12 |
Protein tyrosine kinase |
9.9e-97 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| A. gambiae |
AGAP003651 |
| P. vanderplanki |
Pv.05646 |
| A. aegypti |
AAEL014512 |
| H. sapiens |
ENSP00000377839 |
| H. sapiens |
ENSP00000400868 |
| H. sapiens |
ENSP00000414629 |
| A. mellifera |
GB14040-PA |
| N. vitripennis |
NV14304-PA |
| H. sapiens |
ENSP00000331504 |
| M. musculus |
ENSMUSG00000053158 |
| D. melanogaster |
FBgn0000723 |
| C. quinquefasciatus |
CPIJ005385 |
| M. musculus |
ENSMUSG00000000127 |
| P. humanus |
PHUM259640-PA |
| T. castaneum |
TC004367 |
| H. sapiens |
ENSP00000435811 |
| H. sapiens |
ENSP00000281092 |
| S. invicta |
SI2.2.0_02045 |
| D. plexippus |
DPOGS208227PA |
| H. sapiens |
ENSP00000442627 |
| H. sapiens |
ENSP00000409915 |
| H. sapiens |
ENSP00000377837 |
| H. sapiens |
ENSP00000394297 |
| B. mori |
BGIBMGA006417-TA |
| H. melpomene |
HMEL008372-PA |