MidgeBase gene description page [Pn.04810]
Outline
| Gene ID | Pn.04810 |
| Type | Protein coding gene |
| Scaffold | PnScaf4127 |
| Start | 10312 |
| End | 11817 |
| Direction | - |
Sequence
Transcript: 1065 (bp)
ATGCAGGCCACAAGGTTTCTGAAGAAATTTGTCACTCCAACTGGATGTGCTCGCAACTTTGCTTCGCAGTCGAAAAAAGTGACACTCATTCCCGGTGACGGCATAGGCCCAGAGATTTCTGCAGCCGTTCAAAAAATTTTCGCCGTAGCAAAAGTTCCAATCGAATGGGAAAGTGTTGATGTCACACCGGTTAGAAATCCAGATGGACGTTTTGGAATTCCGCAGGCTGCAATCGATTCTGTGAATCGCAACAAGGTCGGTTTGAAAGGACCTCTTATGACTCCCGTCGGGAAAGGCCATCGATCGCTGAATTTAGCTCTTAGAAAGGAATTTGATCTTTACGCCAACGTTCGTCCGTGCAGAAGCCTCGAGGGCTACAAGACGCTTTACGACGATGTTGATGTGGTCACCATTCGAGAAAACACCGAGGGCGAATATTCGGGAATTGAACACGAAATTGTCGACGGTGTTGTTCAAAGTATCAAACTCATCACCGAGGAGGCCTCAAGACGTGTCTCTGAATATGCCTTCCAATACGCAAAGGACAACCATCGATCAAAAGTGACTGTTGTGCACAAGGCCAACATCATGCGAATGTCGGACGGTCTTTTCTTGCGATGCTGCCGTGAAACTGCTGATAAGTTTCCAGAAATCAAATTCGAGGAGAGTTATCTTGACACGGTTTGCTTGAACATGGTACAAGATCCACGACGATATGATGTACTTGTCATGCCAAATTTATATGGTGATATTTTGTCGGATATGTGTGCTGGTCTCGTTGGTGGCTTAGGTCTCACTCCTTCGGGAAATATTGGTCTTGGTGGTGCACTCTTTGAAAGCGTTCACGGTACTGCTCCCGATATTGCCGGTAAAGATTTGGCAAATCCCACAGCTCTTCTTCTCTCTGCTGTCATGATGCTGCGCCACATGGAAATGAATGACAAAGCCGAGCGAATCCAGCAAGCTTGCTTCGAAACTATTAAGGAGGGCAAATTTCTTACTGGAGACTTGGGTGGAAAGGCCAAATGCTCCGAATTCACGAATGCCATTTGCGAGAAATTGGCT
Protein: 355 (aa)
MQATRFLKKFVTPTGCARNFASQSKKVTLIPGDGIGPEISAAVQKIFAVAKVPIEWESVDVTPVRNPDGRFGIPQAAIDSVNRNKVGLKGPLMTPVGKGHRSLNLALRKEFDLYANVRPCRSLEGYKTLYDDVDVVTIRENTEGEYSGIEHEIVDGVVQSIKLITEEASRRVSEYAFQYAKDNHRSKVTVVHKANIMRMSDGLFLRCCRETADKFPEIKFEESYLDTVCLNMVQDPRRYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNIGLGGALFESVHGTAPDIAGKDLANPTALLLSAVMMLRHMEMNDKAERIQQACFETIKEGKFLTGDLGGKAKCSEFTNAICEKLA
| Type | Start | End | Length |
| CDS |
10315 |
10789 |
475 |
| CDS |
10854 |
11413 |
560 |
| CDS |
11788 |
11817 |
30 |
| intron |
10790 |
10853 |
64 |
| intron |
11414 |
11787 |
374 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_312198 |
AGAP002728-PA [Anopheles gambiae str. PEST] gb|EAA08136.6| AGAP002728-PA [Anopheles gambiae str. PEST] |
0.0 |
| InterPro |
IPR001804 |
Isocitrate/isopropylmalate dehydrogenase |
|
| InterPro |
IPR004434 |
Isocitrate dehydrogenase NAD-dependent |
|
| InterPro |
IPR024084 |
Isopropylmalate dehydrogenase-like domain |
|
| InterPro |
IPR019818 |
Isocitrate/isopropylmalate dehydrogenase, conserved site |
|
| Gene Ontology(BP) |
GO:0006099 |
tricarboxylic acid cycle |
|
| Gene Ontology(BP) |
GO:0055114 |
oxidation-reduction process |
|
| Gene Ontology(MF) |
GO:0000287 |
magnesium ion binding |
|
| Gene Ontology(MF) |
GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
|
| Gene Ontology(MF) |
GO:0004449 |
isocitrate dehydrogenase (NAD+) activity |
|
| Gene Ontology(MF) |
GO:0051287 |
NAD binding |
|
| Pfam |
PF00180.15 |
Isocitrate/isopropylmalate dehydrogenase |
6.3e-105 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. melpomene |
HMEL007998-PA |
| A. gambiae |
AGAP002728 |
| S. invicta |
SI2.2.0_07766 |
| M. musculus |
ENSMUSG00000032279 |
| P. vanderplanki |
Pv.13571 |
| D. plexippus |
DPOGS201094PA |
| P. humanus |
PHUM417630-PA |
| N. vitripennis |
NV19148-PA |
| B. mori |
BGIBMGA007160-TA |
| A. aegypti |
AAEL000454 |
| D. melanogaster |
FBgn0027291 |
| A. mellifera |
GB19422-PA |
| H. sapiens |
ENSP00000453084 |
| H. sapiens |
ENSP00000299518 |
| C. quinquefasciatus |
CPIJ002859 |
| T. castaneum |
TC004962 |
| H. sapiens |
ENSP00000387506 |