MidgeBase gene description page [Pn.04508]
Outline
| Gene ID | Pn.04508 |
| Type | Protein coding gene |
| Scaffold | PnScaf3807 |
| Start | 25454 |
| End | 28880 |
| Direction | - |
Sequence
Transcript: 3276 (bp)
ATGGTGGAAAGTCCGTCGAAAGTCGAGGCTTTCAAGAAAGTAAAAATTTCGCTCTCCCCAAAAAAATTGACAAACGAAAATAATGGCAACTCAATAAATGCACCGATTAAAACTGAGGACGACGATGACGACTCCTGGTTTGCCAACATTGACGAAGATTATTACAAGGCACTTCTGGATAAAAAAAATCCAAAGCAAACACTCGATTTATCGGACTTCAAGAGGTGCAAAGTTCAATCAGTGGATGTGAATGCGAAGGCGTTTGAAAAGATCTTGAGTGTGCAAGAGAAAAAGTCGACAAAGATTGCAAAGTGCTGTCTAAAAGGCATCTGGTTTGACACACAAGTCTCGGAAAATGACGTAGTTTCAGTCAAAGGCACTTGGGATGCAGATCGCCAGATGTTTTTCGTCACCAACGCGAGCGGCATAGTTGTGACGAGCCCGGATCACCTCGTTTCAGGCACAACAATTGTCGGCTCCATGTTTTGCGCTCGAAAATCCGTTTTGCAGGAAAAATTCCGTGGCATCGACGACGGGCCTGATTCACTTATCATGCACATCGGTTCGATTGTTCACGAGATAATTCAGACAGTGATGAAATCGAATCTCACGACAGTCGTCGAAATAAGGCGAGCGACTAACGAGATTTTACGCCATCCGAACATCATTCAGCTGCTGTATTCGTGCCGAATCACGCTGAAAGACCTGCAGACTCAAGTTGAGCCGTTCATCGAGAGAATCCATCAATTCATGCAGCAATATGTATTGGGACATGTCGCCAATCAAACTCCATCGGATGCCAATTCCAACTCAAACAGCGATAAATCATTCAAGGGACGCATCGCCGAGGTCATAGATATCGAGGAGAATGTGTGGAGTCCGCATCTAGGGATGAAAGGAAAGATTGATGCAACCGTTGCGACTTATCCGACAAACAGTTTCATCAACTCGTCTCGCAGGCTCATGCCGATGGAGATAAAGACCGGTCGAGCGTCGCACTCATTCGAGCACAAGGGTCAATTATTAATTTATCAAATGATGTTGCAAGACATGGGGAAGCGCGTCGACTCGGGATTATTGCTTTACATTCGTGAGGGAATTATGAGTGAAATTCGCTCGACACGTCCCGAGCAGAGCGGTCTTGTCACGATGCGAAACAGGCTTGCGAGATATCTGAGCACCGAGATTGTGACGCGCGATAAATCAATCAACTTGCCCGAGCCAATTAAGCATCGCTCTGCATGCGAGTCGTGTGCCTACAACACGCTGTGCTGCGCATTTCTGAGGAAAGAATCGAATCGCGAACTCACCTCCGATCATCCCCTGCTGAAAGTTCAGGAGAGTCGTGCAGGCCACTTGACTGACGCTCATCTAGACTATTTCCTGCACTGGTGCCACTTGATTGCTCTCGAGCACAACGAGGTGCAGAAAAATTTCAAAGTCAAACATCTGTGGACGAGGACGGCCGACGAGAGAGCGGTCAAAGGAACAGCACTCGCAAATTTGATTATAAAAGACCTCGTTATGCCGCAGCACGACGAATTTATACACGCATTCGGAACGGCCGATGACTCTATCGATTTTTCGTCGAAGAACTTTGACATCGGCGACTACCTGATTGTCAGCACCGATAAGAGGTTCTCCATAACGGCTGGTCGTGTGACGGGCATCGATTTGCATCGCATCACTTTATCGCTCCCAAAGGACCTCAATCGGCAGTATGCGAGCGAAAAATTTCATCTCGACAAGTACGAGTCGCAATCGCAGACGATTTTCAACTTCACAAATGTTGGCGTGCTCCTCGAAAACGACACCGAAAGCGAGCGCGGCATTAATCGCTTGAGGAGTATCATTATCGACCGAGAGCCAGCTGTCTTCTCGAATTCTCTGCCGAAATCGATTCAACAGACAATCGACGAGATTTTGATGAAAATGAACTCGGTGCAGCGAACGGCGGTGCTTAAGGCGTTGACTTGCGAAAATTACATGCTAATCAAAGGTTTTCCCGGCACCGGCAAGTCTCAAACGCTCGTCAATCTCATCCACCTGCTGAGTGTGATGCGAAAGAAAATCTTAATTACGAGCCACACCAACTCCGCCGTCGACAACATATTGTTGCGCTTAAAGGAGCGTGGCCTCAAATTTCTGCGCCTAGGCTCCGTTTCGAGGACGCACCAGTCGCTGAGGGAGTTTTGCGAGTCGAAATTGACGGAGGCGTATAAAACGGTCGAGGAGCTGGAGGCCTTCTACGAGAAGTATCAAATTGTCGCAACGACGTGCCTGGGAGCGACTCACGCCATGCTGTCGAGGAGGCGCTTTGACTACTGTCTCGTCGACGAGGCAACGCAAATTTACCAGCCGACCGTCATTCGGCCGCTGCTCTCGGCCGACCGCTTCATTCTCGTCGGAGATCCGGAGCAGTTGGCGCCGCTCGTGCGTAGCAACGACGCTCGCTTGCTCGGCGCTAACGAGAGCCTTTTCGAGCGATTAGACAGCAAGGCGTCGACGTGCGTCCTCGGCCTGCAGTACCGCATGAACAAGACCATCACGAAGCTCGCGAATAATTTGACTTACGGCGGAGAACTCGAGTGCGCTGACGAGCGCGTCGAGAAGGCGACGATGGACGTTCCTTTGTTGTGCAAGCTGAAGGAGGCGTTTGCGAGCGAAAAGTGGCTCGCGAAAATCCTCACGCCGCATCTCGATCAGGCATGCGCTCTCATCAACACCGGTGACGTCTACGAGCGTGCGAGAAGCTTCGGTGACTCGCTCAACACGCCGCGCAACGAAAAGTCTCGGCTGTACGTGAACTACTGCGAAATTGCTATTGTCGTGCGCATTGTCGATCTGCTGATGGAGTGCGGCGTTCTGGGTGAATCAATCGGCATAATTGCTCCGTATCGTGACCAAGTGGAGGCACTTAAGGGCATTTTTAAGAGCGACTCGTATCGTTCGGTGGAGGTCAACACGGTTGACCAGTATCAGGGTCGCGACAAGCAAATCATCATTTACTCGTGCACTTTGTCGGAAACTGCGAGCGACAAGCCGAAGCCATCGTCCGAGGTGGAAATTCTCGAAGATCGCCGTCGTTTGACGGTCGCCATAACGAGAGCGAAGCACAAGCTCATCATGATCGGAGATGTCAATTGCCTCAACAAATACACGCCGTTTAGGGATTTGTTTAAGCACATGAGCGGAATGTCGAAGGTTCAGGTGCAGGACGAGAAATTTGGCTTCTCGTGGACTAGCATGCTCAGTAGTCTTCGGTCAAAATTAGGC
Protein: 1092 (aa)
MVESPSKVEAFKKVKISLSPKKLTNENNGNSINAPIKTEDDDDDSWFANIDEDYYKALLDKKNPKQTLDLSDFKRCKVQSVDVNAKAFEKILSVQEKKSTKIAKCCLKGIWFDTQVSENDVVSVKGTWDADRQMFFVTNASGIVVTSPDHLVSGTTIVGSMFCARKSVLQEKFRGIDDGPDSLIMHIGSIVHEIIQTVMKSNLTTVVEIRRATNEILRHPNIIQLLYSCRITLKDLQTQVEPFIERIHQFMQQYVLGHVANQTPSDANSNSNSDKSFKGRIAEVIDIEENVWSPHLGMKGKIDATVATYPTNSFINSSRRLMPMEIKTGRASHSFEHKGQLLIYQMMLQDMGKRVDSGLLLYIREGIMSEIRSTRPEQSGLVTMRNRLARYLSTEIVTRDKSINLPEPIKHRSACESCAYNTLCCAFLRKESNRELTSDHPLLKVQESRAGHLTDAHLDYFLHWCHLIALEHNEVQKNFKVKHLWTRTADERAVKGTALANLIIKDLVMPQHDEFIHAFGTADDSIDFSSKNFDIGDYLIVSTDKRFSITAGRVTGIDLHRITLSLPKDLNRQYASEKFHLDKYESQSQTIFNFTNVGVLLENDTESERGINRLRSIIIDREPAVFSNSLPKSIQQTIDEILMKMNSVQRTAVLKALTCENYMLIKGFPGTGKSQTLVNLIHLLSVMRKKILITSHTNSAVDNILLRLKERGLKFLRLGSVSRTHQSLREFCESKLTEAYKTVEELEAFYEKYQIVATTCLGATHAMLSRRRFDYCLVDEATQIYQPTVIRPLLSADRFILVGDPEQLAPLVRSNDARLLGANESLFERLDSKASTCVLGLQYRMNKTITKLANNLTYGGELECADERVEKATMDVPLLCKLKEAFASEKWLAKILTPHLDQACALINTGDVYERARSFGDSLNTPRNEKSRLYVNYCEIAIVVRIVDLLMECGVLGESIGIIAPYRDQVEALKGIFKSDSYRSVEVNTVDQYQGRDKQIIIYSCTLSETASDKPKPSSEVEILEDRRRLTVAITRAKHKLIMIGDVNCLNKYTPFRDLFKHMSGMSKVQVQDEKFGFSWTSMLSSLRSKLG
| Type | Start | End | Length |
| CDS |
25457 |
28180 |
2724 |
| CDS |
28254 |
28625 |
372 |
| CDS |
28701 |
28880 |
180 |
| intron |
28181 |
28253 |
73 |
| intron |
28626 |
28700 |
75 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001658902 |
DNA replication helicase dna2 [Aedes aegypti] gb|EAT48794.1| DNA replication helicase dna2 [Aedes aegypti] |
0.0 |
| InterPro |
IPR014808 |
DNA replication factor Dna2 |
|
| InterPro |
IPR022765 |
Dna2/Cas4, domain of unknown function DUF83 |
|
| Gene Ontology(BP) |
GO:0006260 |
DNA replication |
|
| Gene Ontology(MF) |
GO:0003677 |
DNA binding |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0004003 |
ATP-dependent DNA helicase activity |
|
| Pfam |
PF09848.4 |
Uncharacterized conserved protein (DUF2075) |
0.002 |
| Pfam |
PF01656.18 |
CobQ/CobB/MinD/ParA nucleotide binding domain |
0.0029 |
| Pfam |
PF08696.6 |
DNA replication factor Dna2 |
8.5e-50 |
| Pfam |
PF01443.13 |
Viral (Superfamily 1) RNA helicase |
1.5e-08 |
| Pfam |
PF13245.1 |
Part of AAA domain |
6.6e-09 |
| Pfam |
PF12705.2 |
PD-(D/E)XK nuclease superfamily |
4e-11 |
| Pfam |
PF00594.15 |
Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain |
0.32 |
| Pfam |
PF05127.9 |
Helicase |
4e-05 |
| Pfam |
PF13087.1 |
AAA domain |
2.8e-48 |
| Pfam |
PF13604.1 |
AAA domain |
3.2e-10 |
| Pfam |
PF01930.12 |
Domain of unknown function DUF83 |
3.8e-11 |
| Pfam |
PF13086.1 |
AAA domain |
5e-40 |
| Pfam |
PF13361.1 |
UvrD-like helicase C-terminal domain |
0.0018 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| P. vanderplanki |
Pv.14845 |
| P. vanderplanki |
Pv.06588 |
| H. sapiens |
ENSP00000351185 |
| H. sapiens |
ENSP00000389713 |
| H. sapiens |
ENSP00000382132 |
| A. mellifera |
GB19517-PA |
| C. quinquefasciatus |
CPIJ000737 |
| H. sapiens |
ENSP00000450393 |
| S. invicta |
SI2.2.0_05223 |
| A. gambiae |
AGAP004685 |
| D. melanogaster |
FBgn0030170 |
| D. plexippus |
DPOGS206898PA |
| N. vitripennis |
NV12363-PA |
| H. sapiens |
ENSP00000382133 |
| H. melpomene |
HMEL006856-PA |
| T. castaneum |
TC000140 |
| P. humanus |
PHUM444960-PA |
| H. sapiens |
ENSP00000450033 |
| A. aegypti |
AAEL000201 |
| M. musculus |
ENSMUSG00000036875 |