MidgeBase gene description page [Pn.03806]
Outline
| Gene ID | Pn.03806 |
| Type | Protein coding gene |
| Scaffold | PnScaf3122 |
| Start | 854 |
| End | 3675 |
| Direction | + |
Sequence
Transcript: 2667 (bp)
ATGAGTCGTGACGAAAGCATCGATTGGTTTCATGGCAGGATATCCAGAACAGATGCTGAAAACATTCTCCTTGAAGAATCTCAAAAGCTCGACAGCAATGAAAGTATTTTTCTCGTCCGGGAAAGTTCAACTTTAATTAACAATTACGTAGTGTCGGTTATTTATCGAAATGAATTCTTCCATTATCAAATACAAAGACATGGAGATGATTCATTCTTCTCAATTGATTCACAATTTATTCATCACGGATTGGACGATTTGATCGAACACTATAAGCACACGGAGTCGAATTTATGCACCAAGTTGGAGAAGTTTGCGAAGAAAGGTCCACCACCTCTAAAGTATTGTAAACTCGGCAAAGCAAACTTGCTTCATCGCGCAACAAAGCACAACAATCTGAATGTCGTCAAGGAAATCCTTGCGACTTCTTATCGCAATTTGGATGCTAAAGATGAGAATGGTTGTACTGCATTACATTTGGCTGCTTTGAACCGTGTCAGCCCTGAAATTATGAAACTGCTGATAGAGAATGGATGCGCTGTTACAAGTCGCGATTCAAGCGGAAACACAGCACTGCATTACGCTTGTCGTTTTCAGTGCAAGGAGATGGTAGAACTTCTCATAGACGCAAACAAGTCGTTGATTTACGCAAGAAACACATTTACACATGAAGTGCCATTACACGAGGCTGCCAAAATTGGAAACATCGAAATTGTGAAAATTCTGTTGCATCATAAGGCTGCTAGCATGCCTCGTTCGAAAAGTGGACGACTACCTAGTGCTTTTGCCAGGGATAATGGGCATATAGCAGTGGCAGAATATTTAGAGAAGTATTTACCGACATGCAATACATTCAGTCATAAGTGGCATCACGGAACTTTGAATCGTGAAATGGCTCGTACACTCTTGCTCAAGAAAAGAAATGAACTTTATGAGAAATATAGAGAAGATTATGCACAAGAGGAGAATGTATATGTTAACGACAACAAAGAAATTAATGATTTAATTTGTGGCCTTTTTCTTGTAAGATCTTCAGAACGCAATTCAGGCCTTGACGTCATAACAATGCTGCATGATGATGATGAGCTAAAGAATATAAGGAACTATGTCATTCAAAAGTCTGACAGCTCGACTCATTTTTTGTACATTGACGATGGACCGTTCTTTACTTCTTTGGAGCATTTGATAAGCTACTACATGACACATCCCGACGGTTTGCCTGCAAAACTCACCCAATATGTTTCGCCAATTGTTCGTCCTCCAGTTCCCACTCTTCAAATAAAACCAAAAGCAATAGCTCAGTCATCGTCAACAATCAGCACAAGTGCCAGTACATCTACCACGACAGTCCACTCACCGGAAAATGCTAGCAATAATTCAATGATTGCAGATGCTGGTCAGAGCAAATTATCAAAGCCTTCCGTGTTCTCGACTCTCTTCAAGAAAAAGAAACACTCTCTTCCAACTTCACTTTCCAAAGAGGACAAGCCTCAATTGGATCTATCCATGGATACTTTCAACAAGTCGCTCTCCTTTTCAACCAACTTTCTCGACAATCGAGCAGAAAGCTATGATGTGCCACCGAAAAGACCTCCAGCAGACAACCAGGAACAGTTTACTGAAAGCGATAAATATTTGCATAACAATCAATCACCCAACCAAGAGGCAGTGTATTTTGTAGATCCGCCTAAAAGTGCACGTTCCGAGTGGAACCAACTTGATCCAGAGCTTTATGACACACAAAAGAACTTTTTGCTCGAAATAAGTCGCACATCGGGTGCCAACTACTACGTCTCAAAAGACGATCTTCATCACGAACGTGAAATCGGCTCGGGGGAGTTTGGAAATGTACTAAGAGGAATATATAAGCTGTCAAATGGCAAAAAGATTTGGGTTGCTATTAAAACTTTGCACGAAAGACATTACGAGGAGAATTTGCCAGAGTTTTTGAAAGAAGCGTCGGTGATGATTAAACTGGATAATCCATATATTGTTAAACTAATTGGCATCAGCAAGGGGCCGCCAATTGGAATTGTGCAGGAGCTGTGCAGCCTCGGTTCACTTGCTGATTATTTGATCGAGAACAAAAACGAAATCGATAATAATTCGTTTGATTTGTGGGCTTCGCAAATTGCACAAGGAATGGAATATTTAGAATCAAGAAGATTCGTTCATCGTGACCTGGCTGCTCGCAATATTTTGCTTGTGTCAAAACAGCACTGTAAAATTAGCGACTTTGGTCTTTCGCGTGCAATCGGAATTGATAAAGACTTTTATCAATCAAGTACAGGTGGACGATGGCCTTTAAAATGGTATGCGCCAGAGAGTTTTTGCGGGAAGTTTTCTCACTCAAGTGATGTTTGGAGCTTTGGTATCACGCTTTGGGAAATCTATTCAAAAGGCGACGTTCCGTATGGAGATTTATCTGGAGGTGAAGTTAATGAGCTAATCGAGAAAGGTCATCGCTTGGCAAAACCCGATTGCTGCCCTCAGGATGTTTATAGCCTTATGCTTGACTGTTGGCAATATCGTGATCGTCTTCGACCCAACTTTCAATTTCTTGCCAAATTTTTCGTAAATCGTCTCTCCGCTGACGATAAAATTTCTGAAAATCAGAAACCTGAAGATCCAAACGAAACTGAAAAATTGACAAATACAGTGTATGTT
Protein: 889 (aa)
MSRDESIDWFHGRISRTDAENILLEESQKLDSNESIFLVRESSTLINNYVVSVIYRNEFFHYQIQRHGDDSFFSIDSQFIHHGLDDLIEHYKHTESNLCTKLEKFAKKGPPPLKYCKLGKANLLHRATKHNNLNVVKEILATSYRNLDAKDENGCTALHLAALNRVSPEIMKLLIENGCAVTSRDSSGNTALHYACRFQCKEMVELLIDANKSLIYARNTFTHEVPLHEAAKIGNIEIVKILLHHKAASMPRSKSGRLPSAFARDNGHIAVAEYLEKYLPTCNTFSHKWHHGTLNREMARTLLLKKRNELYEKYREDYAQEENVYVNDNKEINDLICGLFLVRSSERNSGLDVITMLHDDDELKNIRNYVIQKSDSSTHFLYIDDGPFFTSLEHLISYYMTHPDGLPAKLTQYVSPIVRPPVPTLQIKPKAIAQSSSTISTSASTSTTTVHSPENASNNSMIADAGQSKLSKPSVFSTLFKKKKHSLPTSLSKEDKPQLDLSMDTFNKSLSFSTNFLDNRAESYDVPPKRPPADNQEQFTESDKYLHNNQSPNQEAVYFVDPPKSARSEWNQLDPELYDTQKNFLLEISRTSGANYYVSKDDLHHEREIGSGEFGNVLRGIYKLSNGKKIWVAIKTLHERHYEENLPEFLKEASVMIKLDNPYIVKLIGISKGPPIGIVQELCSLGSLADYLIENKNEIDNNSFDLWASQIAQGMEYLESRRFVHRDLAARNILLVSKQHCKISDFGLSRAIGIDKDFYQSSTGGRWPLKWYAPESFCGKFSHSSDVWSFGITLWEIYSKGDVPYGDLSGGEVNELIEKGHRLAKPDCCPQDVYSLMLDCWQYRDRLRPNFQFLAKFFVNRLSADDKISENQKPEDPNETEKLTNTVYV
| Type | Start | End | Length |
| CDS |
854 |
929 |
76 |
| CDS |
1014 |
1193 |
180 |
| CDS |
1262 |
3672 |
2411 |
| intron |
930 |
1013 |
84 |
| intron |
1194 |
1261 |
68 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001653430 |
tyrosine-protein kinase shark [Aedes aegypti] gb|EAT39464.1| tyrosine-protein kinase shark [Aedes aegypti] |
1e-168 |
| InterPro |
IPR017441 |
Protein kinase, ATP binding site |
|
| InterPro |
IPR002290 |
Serine/threonine- / dual-specificity protein kinase, catalytic domain |
|
| InterPro |
IPR001245 |
Serine-threonine/tyrosine-protein kinase catalytic domain |
|
| InterPro |
IPR011009 |
Protein kinase-like domain |
|
| InterPro |
IPR000980 |
SH2 domain |
|
| InterPro |
IPR000719 |
Protein kinase, catalytic domain |
|
| InterPro |
IPR020683 |
Ankyrin repeat-containing domain |
|
| InterPro |
IPR008266 |
Tyrosine-protein kinase, active site |
|
| InterPro |
IPR020635 |
Tyrosine-protein kinase, catalytic domain |
|
| InterPro |
IPR002110 |
Ankyrin repeat |
|
| Gene Ontology(BP) |
GO:0006468 |
protein phosphorylation |
|
| Gene Ontology(MF) |
GO:0004713 |
protein tyrosine kinase activity |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0004672 |
protein kinase activity |
|
| Gene Ontology(MF) |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
|
| Pfam |
PF12796.2 |
Ankyrin repeats (3 copies) |
1.8e-26 |
| Pfam |
PF13857.1 |
Ankyrin repeats (many copies) |
9.6e-18 |
| Pfam |
PF00017.19 |
SH2 domain |
1e-23 |
| Pfam |
PF07714.12 |
Protein tyrosine kinase |
3.2e-83 |
| Pfam |
PF13606.1 |
Ankyrin repeat |
3.8e-18 |
| Pfam |
PF00069.20 |
Protein kinase domain |
2.4e-41 |
| Pfam |
PF06293.9 |
Lipopolysaccharide kinase (Kdo/WaaP) family |
0.042 |
| Pfam |
PF13637.1 |
Ankyrin repeats (many copies) |
1.1e-20 |
| Pfam |
PF00023.25 |
Ankyrin repeat |
1.7e-22 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| M. musculus |
ENSMUSG00000021457 |
| N. vitripennis |
NV17869-PA |
| H. sapiens |
ENSP00000264972 |
| P. vanderplanki |
Pv.11658 |
| A. aegypti |
AAEL008732 |
| T. castaneum |
TC004153 |
| H. sapiens |
ENSP00000400475 |
| B. mori |
BGIBMGA003647-TA |
| D. plexippus |
DPOGS215770PA |
| H. sapiens |
ENSP00000411141 |
| C. quinquefasciatus |
CPIJ011800 |
| H. sapiens |
ENSP00000364898 |
| H. sapiens |
ENSP00000364899 |
| H. sapiens |
ENSP00000364904 |
| A. gambiae |
AGAP010710 |
| P. humanus |
PHUM506570-PA |
| H. melpomene |
HMEL014103-PA |
| D. melanogaster |
FBgn0015295 |
| H. sapiens |
ENSP00000364907 |
| M. musculus |
ENSMUSG00000026117 |