MidgeBase gene description page [Pn.03361]
Outline
| Gene ID | Pn.03361 |
| Type | Protein coding gene |
| Scaffold | PnScaf2789 |
| Start | 2707 |
| End | 10438 |
| Direction | - |
Sequence
Transcript: 4359 (bp)
ATGCTCTTAAACACGCATCTCATTAGAAAAGCACCGTCGGCGTACTCGGATGGCGTGTACGGCATGGCCGGCCCCAATCGTCCTTCGCCGCGGAAGCTCAGCCGACTTTTCATGCGCGGCGAGGATGGCCTGAGCTCGATGGAGAACCGGACAGCTCTGCTGGCCTTCTTCGGACAGGTGGTGACCAACGAAATCGTGATGGCTTCCGAGTCCGGATGTCCCATCGAGATGCACCGCATCGAAGTGGAGAAGTGCGACGAGATGTACGACAAAGAGTGCCGCGGCGACCGCTACATTCCCTTTCATCGCGCCATGTACGATCGGAAGACTGGTCAGAGCCCGAATGCGCCGCGCGAACAAATAAATCAAATGACGGCGTGGATCGACGGGAGCTTCATTTACAGCACATCCGAAGCTTGGCTCAACGCAATGCGATCGTTTCAAAATGGATCGCTTCTGACTGATAAGAGCGGTAGCATGCCCGTCAAAAACACGATGCGGGTGCCGCTTTTTAACAATCCCGTGCCGCACGTCATGCGCGCTCTCAGCCCCGAGCGCCTTTATCTTCTGGGCGATCCGCGAACGAACCAAAACCCGGCCGTGCTGACGTTCGCCATCCTCCTCATGCGTTGGCATAACGTGCAGGCACAAGAAGTCAAACGGCTCCATCCGGACTGGAGCGACGAGGAGATTTTCCAGCGCGCGCGCCGACAGGTCATTGCCAGCTTGCAGAGCATTTTCGTGTACGAGTACCTGCCAGCGTTTCTGGGCGGAGTGACGCTCGAGCCTTACACGGGCTACAAGCAAGACATTCATCCCGGCATCTCGCACATGTTTCAAGCCGCCGCGTTTCGCTTTGGACACTCACTCATTCCGCCCGGCATCATGAAGAGAGACGGCAAATGTAATTACAAGTACACGCGAATGGGATCGCCTGCCATTCGACTCTGCTCCACCTGGTGGGACTCGAGCGACATATTTGAAGAGTCGAGCATCGAGGAGTTTCTCATGGGCATGAGCTCGCAGCTGGCCGAGAGAGAGGACCCGTTTCTGTGCTCCGACGTGCGTGACAAGCTGTTTGGACCGATGGAGTTTACGCGCAGAGACCTCGGCGCGCTCAACATCATGCGCGGCCGCGACAACGGACTCGCTGACTTCAACACAGCACGCGCCGCTTACAAGCTCCCACGCTACGAAAACTGGAAAGACATCAACCCGGAGCTGTTCGAGAAGCGTCCCGAGCTCCTGCAGATCCTCATCTCGGCCTACAAGGGCCGCCTCGACAACGTGGACGCCTACATTGGTGGCATGCTCGAGTCGGACGGCAAGCCGGGCGAGCTGTTTACAAACGTGATTCTCGACCAATTCACGCGCATCCGCGACGCCGACCGCTACTGGTTCGAGAACGAAGACAACGGCATCTTCACGCGCGAGGAGATCGAGAAGTTCCGCAGCATTCGCCTCTACGACATCATCGTCAACAGCACAAGTATCGAGCCGGGCCAGATCCAGCGCAATGTTTTCCAGTTCGTCGACGGCGACCCGTGCCCGCAGCCCGAGCAGCTGAACGCGTCGCTGCTGGAGCCGTGCAGCCACATCGAGGGCTACGACTACTTCTCGGGCTCGGAGCTCGCCTACATCTACGCGTGCGTCTTCCTCGGCTTCGTGCCCATCCTGTGCGCCACCGCCGGCTACTGCGTGGTGAAGCTCCAGAACAGCCGTCGACGTCGGCTGAAGGTGAAGCAGGAGACGATGCGCTCGAAGAGCGGCAAGCAGACGGTCGACAAGATGATTGCGCGCGAGTGGCTGCACGCGAACCACAAGCGCCTCGTGACGGTGAAGTTCGGCCCCGAGTCGGCGATCTACACGGTGGACAGGAAGGGCGAGAAGCTGAGGACGTTCAACCTGAAGAACACGGACACCATTCAGGTGGAGTTGAGCGTCGAGAGCTACACGAACAAGCGGCCGCTCGCGCTCCTCCGCATCCACAACGACCACGACCTCGTGCTGGAGCTGGAGACGATCGGAGCGCGCCGGAAGTTCGTCAAGAAGCTCGAGGACTTCCTCATCCTGCACAAGAAGGAGATGTCGATCAACGAGCAGAACCGCGAGCTCATGCTGGCCAAGGCGGAGACGCGCGAGCGCCGCCAGAAGAAACTCGAGCACTTCTTCCGCGAGGCGTATGCGCTGACCTTCGGTCTGCGACCGGGCGAGAGACGCCGTCGCTCGGACGCCTCCAGCGACGGCGAAGTGATGACCGTCATGCGAACCAGCCTCTCGAAGTCGGAGTTCGCGGCCGCTCTCGGCATGAAGCCCGACGCCATGTTCGTGCGGAAGATGTTCAACATCGTCGACAAGGACCAGGACGGCCGCATCTCCTTCCAGGAGTTCCTCGAGACGGTGGTGCTGTTCTCACGCGGCAAGACCGAGGACAAGCTGCGCATCATCTTCGACATGTGCGACAACGACCGCAACGGCGTCATCGACAAGTCCGAGTTCGGCGAGATGATGCGGTCGCTGGTGGAGATTGCGCGAACGACCAGCCTCACCGACGACCAGGTCACGGAGCTGATTGACGGCATGTTCTCGGACTGCGGGCTCGAGCACAAAAATCACCTCACCTACAAGGACTTCAAGGAGATGATGAAGGAGTACAAGGGCGAGTTTGTCGCCATCGGACTCGACTGCAAGGGCGCCAAGCAGAACTTCCTCGACACGTCCACCAACATCGCGCGCATGACGTCGTTCGCGATCGAGCCGACCGAGGGCGAGAAGCACTGGATTCTCGAGAAGTGGGACACCTACACGACCTTCTTGGAGGAGAACCGGCAGAACATCTTCTATCTCTTTCTCTTCTATGTCGTCACCATTGCGCTCTTCGTCGAGCGCTTCATTCACTACTCATTTATGGCTGAACACACTGACTTGCGACACATAATGGGCGTAGGTATTGCGATTACGCGAGGTTCTGCCGCTGCTCTCTCCTTCTGCTACTCCCTCCTCCTGCTGACAATGTCAAGGAACTTCCTCACGAAGCTCAAGGAGTTTCCCATCCAGCAGTATATTCCGCTCGACTCGCACATTCAGTTCCACAAAATCGCCGCTTGCACTGCTCTCTTCTTCTCGCTCCTCCACACCGTCGGCCACATCGTCAACTTCTACCACGTCTCGACGCAGTCGCATGAAAATCTGAGATGCCTCACGCGCGAAGTGCACTTTGCGTCGGACTACAAGCCCGACATCACGTTCTGGCTGTTCAAGACGCTGACCGGTACGACTGGCGTGGCGCTCTTTGTCATCATGTGCATCATCTTCGCCTTCGCCCATCCGACCATCAGAAAGCGCGCCTACAAGTTCTTCTGGCACACGCACTCGCTCTACATCCTGCTCTACATTCTCTCGCTGCTGCACGGTCTCGCAAGAATCTCCGGCGCGCCTCGCTTCTGGATTTTCTTCATCGGTCCCGCGATCATCTTCGTCATCGACAAGGTGGTTTCATTGCGCACGAAATACATGGCGCTCGATGTTATTGACGTCGAGTTGCTGCCGTCTGACGTCATAAAAATCAAGTTTTATCGACCGCCGAATTTGAAGTATTTGTCGGGACAATGGGTGCGGTTTTCGTGCACTGCCATCAAACCCGAGGAGATGCATAGCTTTACGCTAACGTCTGCACCGCACGAGAACTTTTTGAGCTGCCACATTAAGGCGCAGGGACCGTGGACGTGGAAGTTGCGCAACTACTTCGATCCGTGCAACTACAATCCCGACGATCAGCCGAGAATCCGAATCGAGGGACCTTACGGCGGCGGAAATCAAGATTGGTACAAGTTCGAGGTCGCTGTCATGGTTGGCGGTGGCATTGGCGTAACGCCGTATGCGAGCATCTTGAATGACTTGGTCTTCGGCACGAGCACAAACAGATACTCGGGAGTTGCCTGCAAGAAGGTCTACTTCCTCTGGATTTGTCCATCACACAAGCACTTCGAGTGGTTCATCGACGTGCTGCGCGATGTCGAGAAGAAGGACGTGACGAATGTCTTGGAAATACACATTTTCATCACGCAATTCTTCCACAAGTTCGATTTGAGAACGACCATGTTGTACATTTGCGAGAATCACTTCCAGCGGCTCGCAAAGACGTCAATGTTCACGGGACTGAAGGCCGTAAATCACTTCGGTCGTCCCGATATGTCTAGCTTCTTAAAGTTCGTTCAGAAGAAGCACTCGTATGTGTCAAAGATTGGCGTATTCTCATGCGGTCCTAGGCCGCTCACAAAGAGCGTCATGTCGGCATGCGATGAGGTCAACAAGGGACGCAAACTTCCATACTTTATTCACCACTTTGAGAACTTTGGT
Protein: 1453 (aa)
MLLNTHLIRKAPSAYSDGVYGMAGPNRPSPRKLSRLFMRGEDGLSSMENRTALLAFFGQVVTNEIVMASESGCPIEMHRIEVEKCDEMYDKECRGDRYIPFHRAMYDRKTGQSPNAPREQINQMTAWIDGSFIYSTSEAWLNAMRSFQNGSLLTDKSGSMPVKNTMRVPLFNNPVPHVMRALSPERLYLLGDPRTNQNPAVLTFAILLMRWHNVQAQEVKRLHPDWSDEEIFQRARRQVIASLQSIFVYEYLPAFLGGVTLEPYTGYKQDIHPGISHMFQAAAFRFGHSLIPPGIMKRDGKCNYKYTRMGSPAIRLCSTWWDSSDIFEESSIEEFLMGMSSQLAEREDPFLCSDVRDKLFGPMEFTRRDLGALNIMRGRDNGLADFNTARAAYKLPRYENWKDINPELFEKRPELLQILISAYKGRLDNVDAYIGGMLESDGKPGELFTNVILDQFTRIRDADRYWFENEDNGIFTREEIEKFRSIRLYDIIVNSTSIEPGQIQRNVFQFVDGDPCPQPEQLNASLLEPCSHIEGYDYFSGSELAYIYACVFLGFVPILCATAGYCVVKLQNSRRRRLKVKQETMRSKSGKQTVDKMIAREWLHANHKRLVTVKFGPESAIYTVDRKGEKLRTFNLKNTDTIQVELSVESYTNKRPLALLRIHNDHDLVLELETIGARRKFVKKLEDFLILHKKEMSINEQNRELMLAKAETRERRQKKLEHFFREAYALTFGLRPGERRRRSDASSDGEVMTVMRTSLSKSEFAAALGMKPDAMFVRKMFNIVDKDQDGRISFQEFLETVVLFSRGKTEDKLRIIFDMCDNDRNGVIDKSEFGEMMRSLVEIARTTSLTDDQVTELIDGMFSDCGLEHKNHLTYKDFKEMMKEYKGEFVAIGLDCKGAKQNFLDTSTNIARMTSFAIEPTEGEKHWILEKWDTYTTFLEENRQNIFYLFLFYVVTIALFVERFIHYSFMAEHTDLRHIMGVGIAITRGSAAALSFCYSLLLLTMSRNFLTKLKEFPIQQYIPLDSHIQFHKIAACTALFFSLLHTVGHIVNFYHVSTQSHENLRCLTREVHFASDYKPDITFWLFKTLTGTTGVALFVIMCIIFAFAHPTIRKRAYKFFWHTHSLYILLYILSLLHGLARISGAPRFWIFFIGPAIIFVIDKVVSLRTKYMALDVIDVELLPSDVIKIKFYRPPNLKYLSGQWVRFSCTAIKPEEMHSFTLTSAPHENFLSCHIKAQGPWTWKLRNYFDPCNYNPDDQPRIRIEGPYGGGNQDWYKFEVAVMVGGGIGVTPYASILNDLVFGTSTNRYSGVACKKVYFLWICPSHKHFEWFIDVLRDVEKKDVTNVLEIHIFITQFFHKFDLRTTMLYICENHFQRLAKTSMFTGLKAVNHFGRPDMSSFLKFVQKKHSYVSKIGVFSCGPRPLTKSVMSACDEVNKGRKLPYFIHHFENFG
| Type | Start | End | Length |
| CDS |
2710 |
2835 |
126 |
| CDS |
2935 |
3063 |
129 |
| CDS |
3128 |
3363 |
236 |
| CDS |
3739 |
4710 |
972 |
| CDS |
5056 |
6979 |
1924 |
| CDS |
7502 |
7908 |
407 |
| CDS |
8004 |
8208 |
205 |
| CDS |
8590 |
8939 |
350 |
| CDS |
10429 |
10438 |
10 |
| intron |
2836 |
2934 |
99 |
| intron |
3064 |
3127 |
64 |
| intron |
3364 |
3738 |
375 |
| intron |
4711 |
5055 |
345 |
| intron |
6980 |
7501 |
522 |
| intron |
7909 |
8003 |
95 |
| intron |
8209 |
8589 |
381 |
| intron |
8940 |
10428 |
1489 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001658452 |
dual oxidase 1 [Aedes aegypti] gb|EAT40728.1| dual oxidase 1 [Aedes aegypti] |
0.0 |
| InterPro |
IPR017927 |
Ferredoxin reductase-type FAD-binding domain |
|
| InterPro |
IPR002007 |
Haem peroxidase, animal |
|
| InterPro |
IPR018247 |
EF-Hand 1, calcium-binding site |
|
| InterPro |
IPR011992 |
EF-hand-like domain |
|
| InterPro |
IPR002048 |
Calcium-binding EF-hand |
|
| InterPro |
IPR018248 |
EF-hand |
|
| InterPro |
IPR013130 |
Ferric reductase transmembrane component-like domain |
|
| InterPro |
IPR010255 |
Haem peroxidase |
|
| InterPro |
IPR013121 |
Ferric reductase, NAD binding |
|
| InterPro |
IPR019791 |
Haem peroxidase, animal, subgroup |
|
| InterPro |
IPR018249 |
EF-HAND 2 |
|
| InterPro |
IPR013112 |
FAD-binding 8 |
|
| InterPro |
IPR017938 |
Riboflavin synthase-like beta-barrel |
|
| Gene Ontology(BP) |
GO:0006979 |
response to oxidative stress |
|
| Gene Ontology(BP) |
GO:0055114 |
oxidation-reduction process |
|
| Gene Ontology(MF) |
GO:0020037 |
heme binding |
|
| Gene Ontology(MF) |
GO:0004601 |
peroxidase activity |
|
| Gene Ontology(MF) |
GO:0005509 |
calcium ion binding |
|
| Gene Ontology(MF) |
GO:0016491 |
oxidoreductase activity |
|
| Pfam |
PF08022.7 |
FAD-binding domain |
5.2e-19 |
| Pfam |
PF01794.14 |
Ferric reductase like transmembrane component |
3.5e-16 |
| Pfam |
PF12763.2 |
Cytoskeletal-regulatory complex EF hand |
0.0059 |
| Pfam |
PF10591.4 |
Secreted protein acidic and rich in cysteine Ca binding region |
0.0097 |
| Pfam |
PF13499.1 |
EF-hand domain pair |
8.7e-10 |
| Pfam |
PF03098.10 |
Animal haem peroxidase |
5e-132 |
| Pfam |
PF08030.7 |
Ferric reductase NAD binding domain |
5.5e-25 |
| Pfam |
PF00036.27 |
EF hand |
7.4e-14 |
| Pfam |
PF00175.16 |
Oxidoreductase NAD-binding domain |
0.03 |
| Pfam |
PF09069.6 |
EF-hand |
0.049 |
| Pfam |
PF00970.19 |
Oxidoreductase FAD-binding domain |
0.046 |
| Pfam |
PF13833.1 |
EF-hand domain pair |
9.8e-10 |
| Pfam |
PF13405.1 |
EF-hand domain |
3.7e-10 |
| Pfam |
PF13202.1 |
EF hand |
2.2e-09 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| M. musculus |
ENSMUSG00000068452 |
| H. sapiens |
ENSP00000400283 |
| B. mori |
BGIBMGA005478-TA |
| S. invicta |
SI2.2.0_02883 |
| H. sapiens |
ENSP00000317997 |
| M. musculus |
ENSMUSG00000033268 |
| H. melpomene |
HMEL017581-PA |
| A. gambiae |
AGAP009978 |
| H. sapiens |
ENSP00000454065 |
| N. vitripennis |
NV11842-PA |
| T. castaneum |
TC002498 |
| S. invicta |
SI2.2.0_15117 |
| P. humanus |
PHUM454140-PA |
| T. castaneum |
TC004592 |
| A. mellifera |
GB13459-PA |
| D. melanogaster |
FBgn0031464 |
| D. plexippus |
DPOGS207783PA |
| H. sapiens |
ENSP00000373691 |
| P. vanderplanki |
Pv.08799 |
| A. aegypti |
AAEL007563 |
| H. sapiens |
ENSP00000373689 |
| C. quinquefasciatus |
CPIJ003117 |
| H. sapiens |
ENSP00000452623 |