MidgeBase gene description page [Pn.02862]
Outline
| Gene ID | Pn.02862 |
| Type | Protein coding gene |
| Scaffold | PnScaf2465 |
| Start | 16021 |
| End | 19649 |
| Direction | - |
Sequence
Transcript: 1953 (bp)
ATGTGTGGTATTTCGGATGAGCTGGGCTGCCATCACACGAGCACCTGCACGGAGGCGACGCGCGGTGGCTGTGAGCACCACTGCACGAATCTCACAGAAAGTGGATACATTTGCAGCTGTTTCCAGGGCTACATCATTGACGCGACCAACAAGAAGAAGTGCGTCGACGTAGACGAGTGTGCGACTGGAACGAGCATGTGCTCGCAGATTTGTAATAATCTCAACGGCACATACGCGTGCGCTTGCAATAATGGTTTCAAGCTTGCCGACGGCGCAGCCGGAATATGCAAAGCCGAAAAAGATGAGACAACCGTCATCTTCACAACGGGTACAAATATCAGAGCATTCAATCTGAAGGAGAACAAGGAGTTTGATGTGATCGCCTCAGAAAAGCGAATCGAGTCGATTGACTATGACCCTAGAAAACAGATGGTATTTTGGGCGGACAGCAATGATCGCACTATCAAGCGCTCGTATATGGTCAATGCGATGGACGGGCAGGCAAAGGTTGGCTTCGCACAGGATCTCAATATGAAGGGAAATTCAAAGCCGACGGCTGTGGCAGTCGACTGGATCGCCGAGAACTTGTATTGGACTGAAACGGACCGAACTGGAAGCAAGCCGCGTGGCCGAGTGATGGTGGCAAAAACTGACGGTCGTTATCGTCGTGCGTTGGTTAACAATGGTCTCGAAATTCCAACGGCGATTGCGGTAGATCCGCAATTGGGGCGACTTTATTGGTCAGACGCGGGCTCGGCGCCGAAAATCGAAGTCTCGTGGATGGATGGCAGCCGAAGAAAGCCATTAATTGTGGACGGAATTAGACACCCGGCTGGCGTGACCATTGACTACGATCAGGAGCACCGAATCTATTGGGTTGATACGAAATTGAATATGATCGAATCAGTAAAGCCGGACGGAACGCTGAGAAAGGTGGTGGCGCGGGGCGAGCAACTTCGCCATCCAATTTCACTAGATATTTTTGAGTCGAATCTATATTGGGTTTCACGCGATACCGGCGATCTCATCAAGCAGGACAAATTTGGTCGAGGCGTACAGGTTGTCATACAGCGTGACATAGTAAATCCTGCCGGTGTCAAAATTTATCACGAAAACCGTTACAATACGTCACTAAAGAATCCATGCTTCAAGAGCACGTGTTCGCACCTATGTCTTCTCGTGCCAGGCGGATGGCGTTGCGCTTGTCCCGACAACTCTGTTCAACCGCAAAACCATCGAAGCACAGCTGAGGTCATTTGTGATGCAGTCGCTGAAAGAGAGAGACCATTGCCGAGAGTATGCAAATGCCAAAATGGTGGTTTCTGCAAGGAGGATGACAGTGGCGAGGTCATATGCGACTGTCAGCCGGACTTCCTCGGCAAGCACTGTGAGAAGTTCACGGGAGTGTCGCATACTGTAGGAGGAAACTCGACTGCTGCTGTTCTTATACCAATTCTAATTCTAGCACTCATGGGTGCTGCGGTGGGTTCATGGTTTGTCATCAAGAAAAGACCATTTGGAAAGGCAACGCTGGGATTGTCATCGTCACAAAGTGTGTCCTTCCGACACGGCACCAACGTGGAGTTCAACTCTCCGGGATTCTCAGCAGGTTCGCCCACATCACCGTCGCTTGCGACCGACCAAATCCCACCAATGGATTCTTATAATCTGGAAACATTGAGTAACAAGAATCGAGACTTCTCGAATCCCATGTATGACGCCGTGCAGTCAGACACACACATGTCACGAATATACGATGTGCCACCAGCAGAAACAAACCCAAAAGATCCAAATGCACCAATGGAGCCGGGATCAGCAATAATTGCTCCCAGTAGCATAGTTCATCGAACATCACCACAATTACAAATAAGGAAGCCTCGGGAGCTAGATCCTTCTGCTGAGGACACGGGCAAAGATACACAAGCCCTCGTGGAAGAAGACAAATCCGAATGC
Protein: 651 (aa)
MCGISDELGCHHTSTCTEATRGGCEHHCTNLTESGYICSCFQGYIIDATNKKKCVDVDECATGTSMCSQICNNLNGTYACACNNGFKLADGAAGICKAEKDETTVIFTTGTNIRAFNLKENKEFDVIASEKRIESIDYDPRKQMVFWADSNDRTIKRSYMVNAMDGQAKVGFAQDLNMKGNSKPTAVAVDWIAENLYWTETDRTGSKPRGRVMVAKTDGRYRRALVNNGLEIPTAIAVDPQLGRLYWSDAGSAPKIEVSWMDGSRRKPLIVDGIRHPAGVTIDYDQEHRIYWVDTKLNMIESVKPDGTLRKVVARGEQLRHPISLDIFESNLYWVSRDTGDLIKQDKFGRGVQVVIQRDIVNPAGVKIYHENRYNTSLKNPCFKSTCSHLCLLVPGGWRCACPDNSVQPQNHRSTAEVICDAVAERERPLPRVCKCQNGGFCKEDDSGEVICDCQPDFLGKHCEKFTGVSHTVGGNSTAAVLIPILILALMGAAVGSWFVIKKRPFGKATLGLSSSQSVSFRHGTNVEFNSPGFSAGSPTSPSLATDQIPPMDSYNLETLSNKNRDFSNPMYDAVQSDTHMSRIYDVPPAETNPKDPNAPMEPGSAIIAPSSIVHRTSPQLQIRKPRELDPSAEDTGKDTQALVEEDKSEC
| Type | Start | End | Length |
| CDS |
16024 |
16232 |
209 |
| CDS |
17258 |
17484 |
227 |
| CDS |
17560 |
17809 |
250 |
| CDS |
18258 |
19512 |
1255 |
| CDS |
19638 |
19649 |
12 |
| intron |
16233 |
17257 |
1025 |
| intron |
17485 |
17559 |
75 |
| intron |
17810 |
18257 |
448 |
| intron |
19513 |
19637 |
125 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001660469 |
low-density lipoprotein receptor (ldl) [Aedes aegypti] gb|EAT38205.1| low-density lipoprotein receptor (ldl) [Aedes aegypti] |
0.0 |
| InterPro |
IPR000033 |
LDLR class B repeat |
|
| InterPro |
IPR018097 |
EGF-like calcium-binding, conserved site |
|
| InterPro |
IPR001881 |
EGF-like calcium-binding |
|
| InterPro |
IPR006210 |
Epidermal growth factor-like |
|
| InterPro |
IPR000742 |
Epidermal growth factor-like domain |
|
| InterPro |
IPR009030 |
Growth factor, receptor |
|
| InterPro |
IPR011042 |
Six-bladed beta-propeller, TolB-like |
|
| InterPro |
IPR013032 |
EGF-like, conserved site |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0005509 |
calcium ion binding |
|
| Pfam |
PF12662.2 |
Complement Clr-like EGF-like |
7.4e-07 |
| Pfam |
PF00058.12 |
Low-density lipoprotein receptor repeat class B |
3e-25 |
| Pfam |
PF00008.22 |
EGF-like domain |
9.3e-07 |
| Pfam |
PF08450.7 |
SMP-30/Gluconolaconase/LRE-like region |
0.012 |
| Pfam |
PF07645.10 |
Calcium-binding EGF domain |
1.5e-08 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
| Gene ID |
| Pn.04154 |
| Pn.13045 |
| Pn.05082 |
| Pn.12040 |
| Pn.06251 |
| Pn.03056 |
Orthologous genes
| Species |
Gene ID |
| T. castaneum |
TC007146 |
| P. humanus |
PHUM038270-PA |
| A. gambiae |
AGAP000331 |
| S. invicta |
SI2.2.0_80786 |
| T. castaneum |
TC004042 |
| P. vanderplanki |
Pv.04554 |
| M. musculus |
ENSMUSG00000027070 |
| H. sapiens |
ENSP00000436652 |
| D. melanogaster |
FBgn0004649 |
| M. musculus |
ENSMUSG00000024913 |
| C. quinquefasciatus |
CPIJ020278 |
| H. sapiens |
ENSP00000294304 |
| H. sapiens |
ENSP00000261349 |
| B. mori |
BGIBMGA001048-TA |
| D. melanogaster |
FBgn0030706 |
| H. sapiens |
ENSP00000445083 |
| D. plexippus |
DPOGS211883PA |
| P. humanus |
PHUM449100-PA |
| P. vanderplanki |
Pv.13645 |
| H. melpomene |
HMEL010093-PA |
| N. vitripennis |
NV12504-PA |
| C. quinquefasciatus |
CPIJ000808 |
| H. sapiens |
ENSP00000243077 |
| A. gambiae |
AGAP000427 |
| A. aegypti |
AAEL009806 |
| H. sapiens |
ENSP00000393859 |
| T. castaneum |
TC004414 |
| T. castaneum |
TC004260 |
| N. vitripennis |
NV13371-PA |
| H. sapiens |
ENSP00000367888 |
| T. castaneum |
TC009548 |
| S. invicta |
SI2.2.0_04586 |
| M. musculus |
ENSMUSG00000030201 |
| A. mellifera |
GB16571-PA |
| H. sapiens |
ENSP00000374135 |
| A. aegypti |
AAEL014222 |
| P. vanderplanki |
Pv.08374 |
| H. sapiens |
ENSP00000451737 |
| P. humanus |
PHUM507180-PA |
| B. mori |
BGIBMGA001256-TA |
| H. melpomene |
HMEL005758-PA |
| B. mori |
BGIBMGA011982-TA |
| H. melpomene |
HMEL016558-PA |
| P. vanderplanki |
Pv.06511 |
| T. castaneum |
TC008596 |
| D. plexippus |
DPOGS200714PA |
| D. melanogaster |
FBgn0053087 |
| T. castaneum |
TC008151 |
| H. sapiens |
ENSP00000409813 |
| A. aegypti |
AAEL010712 |
| H. melpomene |
HMEL005166-PA |
| H. sapiens |
ENSP00000451449 |
| H. sapiens |
ENSP00000341264 |
| D. plexippus |
DPOGS203530PA |
| A. aegypti |
AAEL009869 |
| B. mori |
BGIBMGA014161-TA |
| N. vitripennis |
NV50398-PA |
| A. aegypti |
AAEL007041 |
| B. mori |
BGIBMGA009172-TA |
| A. mellifera |
GB12775-PA |
| D. plexippus |
DPOGS210344PA |
| M. musculus |
ENSMUSG00000027253 |
| C. quinquefasciatus |
CPIJ014519 |
| H. sapiens |
ENSP00000442472 |
| M. musculus |
ENSMUSG00000049252 |
| C. quinquefasciatus |
CPIJ017507 |
| P. humanus |
PHUM470230-PA |
| D. plexippus |
DPOGS216174PA |
| D. melanogaster |
FBgn0261260 |
| D. melanogaster |
FBgn0000119 |
| H. sapiens |
ENSP00000415052 |
| C. quinquefasciatus |
CPIJ004220 |
| H. sapiens |
ENSP00000413239 |
| P. humanus |
PHUM086410-PA |
| N. vitripennis |
NV14309-PA |
| H. sapiens |
ENSP00000263816 |
| A. mellifera |
GB11226-PA |
| S. invicta |
SI2.2.0_16473 |
| A. gambiae |
AGAP012372 |
| A. aegypti |
AAEL007657 |
| D. plexippus |
DPOGS203529PA |
| H. melpomene |
HMEL006767-PA |
| A. gambiae |
AGAP000037 |
| A. gambiae |
AGAP011770 |