MidgeBase gene description page [Pn.02465]
Outline
| Gene ID | Pn.02465 |
| Type | Protein coding gene |
| Scaffold | PnScaf2073 |
| Start | 5370 |
| End | 9717 |
| Direction | + |
Sequence
Transcript: 2565 (bp)
ATGAACAATGAGATTTGCATGCTACCAGTATTTTATTGGCCTCTTCAGATGAGAGCCGTTTCGAGTCCTTCGCTAACAGAAAACCCCGTAGAAACCTCACCCTCGTGCACTGCGTCGCCAAAGCCGTTCTCGGGCAAGCCAAACGAGCCGAACGGTCACATACAGAATCACACTGAGCTTAGTGATCGAAATCAAACAGCATCCACCGGCGTTCTGCAAAAGTTCAAGAAGACGTTTTCGAATTTCAAGCACGGCAAGGCCGTAGCAGTCAACGAGGAGCAAAGCGATGCCAAACACCATCGATTCGGACCATTAGTGTGGCGAACGAGCAAGGAGCGGCGAAAGACCAAAACTCATCGACGAGACAAGTGCAATTCGGGCGACTCGGGCATTCAAGTTGAGCTGGAGAACGACGAAAATTTGCCGGAAAATGTGTCACCGCAACAGATGGATATTTCGCCGCAGCTGAAGGGCAGCAGCAGCAGCAACAGTGCCAAAGTAAGACGTGCCAATAGCGCAAAAGTTTCAACCACAACAAAGTCAGCGAAAAACAGCTCGGACGCGAAGAGCGCGGGAAAGTCGAAGCGCTCGCTCAGTCAGCCATCGGATCTGGACGTGATCGTCTGCGAGAGCAAGATGATGGACAACCTGGACGACATCAAGCACATCGATGACGACGACGACGCCTCCTCCGACACGGACAGTCTCAGCTCCGCCAATCACGAGCTAGACGACGAGGACGCGCACAGAGGTGGCGCGGTGGTTTATGCCGAGGTGCTCTACCAGTTTAGGGCAGGCGGACCGTGCGAGTTGTCGCTCGAGAAGGGCGCACTCGTCGAGGTGATAAAGCGCGAGAGTGGGCCGTGGTGGTGGGGCCGAATAAAGTACGACGGCCTAACAAACGAGAGCGAGGCGGAGACGAGTCAGGGATGGTTTCCGAAGGACTTCGTCAAGCTACTGCCGAGCTACGCGAACCGCAAGTATTTTCAGCACCAATCGTCAAACGACTGTGATATCAACGCCACACTCCCGCCATCTGCCGCCGCAGCGCCAACCATCTCATCTAGTCAATCGAACAGCGAACTCATGCGAGACAACGTCATCAAGGAGCTCCTCGAGACGGAAATTAATTACGTCAAGCTGCTGAATTCCCTTGTCAATGGATTCATCAAGGAAATGAAGGAGCGCACCGATGTCTTCTCGCAGGACAGCATTTTCCTCATGTTCTCGAATATCGAGCAGATTTACCGCTTCCAGCAGAACTTCCTCGAGGCGCTGCGCATCGCCATCCCGAACGGACGAATCGCAGAAGTCTTCTTGGACTTTCAGTCCGCTTTCATGGTCTACTCGCAGTACTGCAACTCATATCCGAGGGCCCTCATGGAACTCGAGAACTTTTCGAACAATAAGGAGGCGGCCGGCATTCTAGAGAGCTGCCGCACTGCACAAAACCTCCCCGAGTTACCGCTGTCGGCGCACTTGCTGGCGCCAATTCAGAGAATTTGTCGATATCCGCTGCACTTAAGCGAGCTGGTGAAGCACTCGAAGACCCGCAAGGAAATCCTGCTGAAGACGGACGTGCAGTCGCTGAGTCGGAACGACTTCGAGACAATCGACTGCAAGGAGATGTTCGATCTCGCGCTGAACGCAATGAAACGCGTCACCGAGATGGTGAACGAGGGCAAACGTCACAGCGAGTATCTGTCGCGGATGCAGGCACGTTTCGAGAACTTCCAAGGGCCATCGATAAACCTGCACAGCACGCGGCTCTTCCTTCAGACGGACGCGATCCGAGTGTCGCCGAATCTGTGGAACAACACGTACACGCTCTTCCTCTTCGACCGGCAGCTCATCTACTGCAAGAAGGACCTGCTAAAGCGCACCAGCTACATCTACAAGGGCCGAATCTTCCTCGACAATTGCCGCATCCTCAACCTCCCCGACGGCCGCATGTTCGGCGTCAATCTCAAGAACGCCCTGCGCATCTTCTGCGAGGCACGCGGCAAGTGGTTCGACTTCTGCTTCCGCTCAAGCTCGAGCAAGACGCGCTTCCTCAACACACTCTCGGCCGAGCGACAGTTCTGCGGCTCGAGCCTCTTCGTGTCGGAGATCGCTTCGGGCTTGGACGACGAGAACTTGTCGGACGACGTGAACGCACTCGTGCAGGACTACGACGAGCGCGCCATCGATGTCGAGCAGGCGCTTCTAGCGAACGGAAACAATTCGGCGGCGGCCGAGTCGCCGTTGAAGCAGCAAAAGTTCAGCGACTCGCTGCCGAAGAAGTCGCGCAAGTTGTCGAAGGAAGCGGCGCCCTCGCAAATCATCATCGACTACAACCCGGCGGCGACTTCGTCGTCCAGCAGGCGTCGCCTCGGCAACTGGTTCCGGAAGTCAAAGAGCACCAACAGCACACCGTCACAGAGTCCCACGCACCATCCGCTGGTCGCGACCGCAACCGTGCCATCGATCGTGAACCACTCCGACAGCAACTCCTCGTCGCAGAGCTCGCCCGTCAACTATCCGCGGCCGAAGTTTAAGGAGGCCGCCAGCGTCGGCGGATCGTCC
Protein: 855 (aa)
MNNEICMLPVFYWPLQMRAVSSPSLTENPVETSPSCTASPKPFSGKPNEPNGHIQNHTELSDRNQTASTGVLQKFKKTFSNFKHGKAVAVNEEQSDAKHHRFGPLVWRTSKERRKTKTHRRDKCNSGDSGIQVELENDENLPENVSPQQMDISPQLKGSSSSNSAKVRRANSAKVSTTTKSAKNSSDAKSAGKSKRSLSQPSDLDVIVCESKMMDNLDDIKHIDDDDDASSDTDSLSSANHELDDEDAHRGGAVVYAEVLYQFRAGGPCELSLEKGALVEVIKRESGPWWWGRIKYDGLTNESEAETSQGWFPKDFVKLLPSYANRKYFQHQSSNDCDINATLPPSAAAAPTISSSQSNSELMRDNVIKELLETEINYVKLLNSLVNGFIKEMKERTDVFSQDSIFLMFSNIEQIYRFQQNFLEALRIAIPNGRIAEVFLDFQSAFMVYSQYCNSYPRALMELENFSNNKEAAGILESCRTAQNLPELPLSAHLLAPIQRICRYPLHLSELVKHSKTRKEILLKTDVQSLSRNDFETIDCKEMFDLALNAMKRVTEMVNEGKRHSEYLSRMQARFENFQGPSINLHSTRLFLQTDAIRVSPNLWNNTYTLFLFDRQLIYCKKDLLKRTSYIYKGRIFLDNCRILNLPDGRMFGVNLKNALRIFCEARGKWFDFCFRSSSSKTRFLNTLSAERQFCGSSLFVSEIASGLDDENLSDDVNALVQDYDERAIDVEQALLANGNNSAAAESPLKQQKFSDSLPKKSRKLSKEAAPSQIIIDYNPAATSSSSRRRLGNWFRKSKSTNSTPSQSPTHHPLVATATVPSIVNHSDSNSSSQSSPVNYPRPKFKEAASVGGSS
| Type | Start | End | Length |
| CDS |
5370 |
5408 |
39 |
| CDS |
6100 |
6259 |
160 |
| CDS |
6329 |
6431 |
103 |
| CDS |
6966 |
7113 |
148 |
| CDS |
7191 |
7903 |
713 |
| CDS |
7975 |
8244 |
270 |
| CDS |
8583 |
9714 |
1132 |
| intron |
5409 |
6099 |
691 |
| intron |
6260 |
6328 |
69 |
| intron |
6432 |
6965 |
534 |
| intron |
7114 |
7190 |
77 |
| intron |
7904 |
7974 |
71 |
| intron |
8245 |
8582 |
338 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001663446 |
rho guanine exchange factor [Aedes aegypti] gb|EAT34485.1| rho guanine exchange factor [Aedes aegypti] |
0.0 |
| InterPro |
IPR001452 |
Src homology-3 domain |
|
| InterPro |
IPR011993 |
Pleckstrin homology-like domain |
|
| InterPro |
IPR000219 |
Dbl homology (DH) domain |
|
| InterPro |
IPR001849 |
Pleckstrin homology domain |
|
| Gene Ontology(BP) |
GO:0035023 |
regulation of Rho protein signal transduction |
|
| Gene Ontology(CC) |
GO:0005622 |
intracellular |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0005543 |
phospholipid binding |
|
| Gene Ontology(MF) |
GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
|
| Pfam |
PF00621.15 |
RhoGEF domain |
3.4e-38 |
| Pfam |
PF07653.12 |
Variant SH3 domain |
8.2e-05 |
| Pfam |
PF00018.23 |
SH3 domain |
6.9e-07 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| M. musculus |
ENSMUSG00000021990 |
| H. sapiens |
ENSP00000371542 |
| H. sapiens |
ENSP00000348017 |
| D. melanogaster |
FBgn0264707 |
| H. sapiens |
ENSP00000371527 |
| H. sapiens |
ENSP00000364006 |
| P. vanderplanki |
Pv.02905 |
| H. sapiens |
ENSP00000364012 |
| H. sapiens |
ENSP00000386471 |
| A. mellifera |
GB13057-PA |
| P. humanus |
PHUM269380-PA |
| A. gambiae |
AGAP006382 |
| A. aegypti |
AAEL013280 |
| H. sapiens |
ENSP00000399994 |
| H. sapiens |
ENSP00000316845 |
| H. sapiens |
ENSP00000387285 |
| M. musculus |
ENSMUSG00000025656 |
| H. sapiens |
ENSP00000401605 |
| T. castaneum |
TC004065 |
| H. sapiens |
ENSP00000398560 |
| H. sapiens |
ENSP00000343631 |
| H. sapiens |
ENSP00000253401 |
| H. sapiens |
ENSP00000371576 |
| H. sapiens |
ENSP00000382830 |
| C. quinquefasciatus |
CPIJ004982 |
| H. sapiens |
ENSP00000432267 |
| H. sapiens |
ENSP00000364004 |
| H. sapiens |
ENSP00000432301 |
| S. invicta |
SI2.2.0_80505 |
| H. sapiens |
ENSP00000376680 |