MidgeBase gene description page [Pn.02250]
Outline
| Gene ID | Pn.02250 |
| Type | Protein coding gene |
| Scaffold | PnScaf1903 |
| Start | 72184 |
| End | 74602 |
| Direction | + |
Sequence
Transcript: 1641 (bp)
ATGCAGATAGGATTACCGACCAATGTGGTTCGAGGATTGCATGTGAGCAAAAACCAGGTAACAGGCGATTTGGAAGGATTGCCAAAGCAATGGCAGAAACTACTCAAGACGGCGATAACGAAAGATGAGCAAAATGAAAATCCCGACGCAGCCTATCAAGCGGTGAAATTTTACAACTACTCAATAAAAAAGAAAGACAACATCGAGCCATTCAAGCCGTTTTACACCGAAGCCGTATTCAACGAGGAGTCCGAGGAAATCGAGGATTTTCTGAAGAGCAATGAACACAACTCGGGTGACTCGTTCCGTGACGAAGAGAGAAGCAGCAATGAGGATAATAGCTTGACAACGACAGAACCGCCGACGGTCTACGACCCCGAGCTTCCGCCCGATCTACCGCCACCGCTGCCGGAGAAAACGCCGAGCAGGGCTGTTTCGGTCAAGCCACCGATCGGGCCCAAGCCCAGCATTAAGAAGCCGGCTCGCAATTTTCCACTCAAGAAAACACCGCATGGACCCATGCAAGATTTAAGAGACATCGATAAGGAAGTGAATGATAATAATATCGATTATACGAAATCAACGACATATGCCAAAAATCATGACTTATCAGCGCTCAACGATAACGACTTCCCCAATAACAATGAAACGTTCATAGTTGTGCCGGATAATAATAATAAGGATAATAGCGAGAAGGAGGAGGAGACGCCGACTTTGCGAACAAAGAAACCCGCGCGCGTTACGATGACGGACGAGCAAGTGTATGCGGAGCTGAGGAGCATATGCAACATGTCAGATCCGTTGGAGAAGTATAAACAAACGAAGGAAGTCGGCAAGGGAGCGAGCGGAGTTGTGTTCATAGCCCAAGAATTAGGAACAGATAAACAAGTTGCCATCAAAACAATTGATCTTAAGAATCAGTCTTCCAAAGAGCTCATTCTGAATGAGATTCGAGTACTGAAGGATTTCAATCACAGGAACTTAGTCAATTTCCTCGATGCCTACTTTCTCGAGGAGAAGGATCATTTGTGGGTCGTGCTAGAGTACATGAACGGAGGCCCACTAACTGATGTTGTCACAGAAACAGTCATGAACGAGCGTCAAATTTCTGCAGTTTGTCGCGAGGTGCTCAATGCAATAAGTTTCCTTCACCAGAAGGGAATCATCCATCGAGACATTAAGTCGGACAACGTGCTGTTGGGTCTCGATGGAAAAGTGAAAGTAACGGATTTCGGATTTTGTGCAAATATCGAGGAGCATGAGAAGCGCGAAACAATGGTCGGAACACCTTACTGGATGGCGCCCGAGGTCGTGACGCGAAAACAATACGGAAAGAAGGTTGACGTCTGGTCGCTCGGAATTATGGCAATAGAAATGATCGAGGGCCAGCCACCATATTTGAATCAAGCGCCACTGCGTGCTCTTTATCTAATCGCAGCGAACGGAAGACCGGAAATCAAGTCATGGGAGAAGCTATCTGAACCGCTGAAAGATTTCCTCAACTGCTGTCTAGAAGTTGAGGTTGATAAGCGAGCATCGGCTCGCGAGTTATTGGATCATCCTTTCCTAAAGGATTGTGCCGAGCTTAAAAGTTTAACGCCACTTATTCGCGCCGCGAGACGAATTTTAAACAGGGACAAG
Protein: 547 (aa)
MQIGLPTNVVRGLHVSKNQVTGDLEGLPKQWQKLLKTAITKDEQNENPDAAYQAVKFYNYSIKKKDNIEPFKPFYTEAVFNEESEEIEDFLKSNEHNSGDSFRDEERSSNEDNSLTTTEPPTVYDPELPPDLPPPLPEKTPSRAVSVKPPIGPKPSIKKPARNFPLKKTPHGPMQDLRDIDKEVNDNNIDYTKSTTYAKNHDLSALNDNDFPNNNETFIVVPDNNNKDNSEKEEETPTLRTKKPARVTMTDEQVYAELRSICNMSDPLEKYKQTKEVGKGASGVVFIAQELGTDKQVAIKTIDLKNQSSKELILNEIRVLKDFNHRNLVNFLDAYFLEEKDHLWVVLEYMNGGPLTDVVTETVMNERQISAVCREVLNAISFLHQKGIIHRDIKSDNVLLGLDGKVKVTDFGFCANIEEHEKRETMVGTPYWMAPEVVTRKQYGKKVDVWSLGIMAIEMIEGQPPYLNQAPLRALYLIAANGRPEIKSWEKLSEPLKDFLNCCLEVEVDKRASARELLDHPFLKDCAELKSLTPLIRAARRILNRDK
| Type | Start | End | Length |
| CDS |
72184 |
72334 |
151 |
| CDS |
72595 |
73498 |
904 |
| CDS |
73686 |
73755 |
70 |
| CDS |
73927 |
74099 |
173 |
| CDS |
74195 |
74268 |
74 |
| CDS |
74331 |
74599 |
269 |
| intron |
72335 |
72594 |
260 |
| intron |
73499 |
73685 |
187 |
| intron |
73756 |
73926 |
171 |
| intron |
74100 |
74194 |
95 |
| intron |
74269 |
74330 |
62 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001656999 |
P21-activated kinase, pak [Aedes aegypti] gb|EAT48491.1| P21-activated kinase, pak [Aedes aegypti] |
0.0 |
| InterPro |
IPR017441 |
Protein kinase, ATP binding site |
|
| InterPro |
IPR000719 |
Protein kinase, catalytic domain |
|
| InterPro |
IPR002290 |
Serine/threonine- / dual-specificity protein kinase, catalytic domain |
|
| InterPro |
IPR000095 |
PAK-box/P21-Rho-binding |
|
| InterPro |
IPR020635 |
Tyrosine-protein kinase, catalytic domain |
|
| InterPro |
IPR008271 |
Serine/threonine-protein kinase, active site |
|
| InterPro |
IPR011009 |
Protein kinase-like domain |
|
| Gene Ontology(BP) |
GO:0006468 |
protein phosphorylation |
|
| Gene Ontology(MF) |
GO:0004713 |
protein tyrosine kinase activity |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0004674 |
protein serine/threonine kinase activity |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0004672 |
protein kinase activity |
|
| Gene Ontology(MF) |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
|
| Pfam |
PF00069.20 |
Protein kinase domain |
1.2e-71 |
| Pfam |
PF06293.9 |
Lipopolysaccharide kinase (Kdo/WaaP) family |
0.049 |
| Pfam |
PF00786.23 |
P21-Rho-binding domain |
7.5e-15 |
| Pfam |
PF01636.18 |
Phosphotransferase enzyme family |
0.00094 |
| Pfam |
PF07714.12 |
Protein tyrosine kinase |
1.1e-48 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000429113 |
| P. vanderplanki |
Pv.12373 |
| H. sapiens |
ENSP00000262836 |
| B. mori |
BGIBMGA010956-TA |
| N. vitripennis |
NV15829-PA |
| A. gambiae |
AGAP001790 |
| H. sapiens |
ENSP00000410853 |
| D. melanogaster |
FBgn0044826 |
| M. musculus |
ENSMUSG00000022781 |
| D. melanogaster |
FBgn0014001 |
| P. vanderplanki |
Pv.05345 |
| B. mori |
BGIBMGA007577-TA |
| H. sapiens |
ENSP00000431541 |
| D. plexippus |
DPOGS203416PA |
| H. sapiens |
ENSP00000433211 |
| H. sapiens |
ENSP00000433423 |
| H. melpomene |
HMEL003627-PA |
| H. sapiens |
ENSP00000389172 |
| N. vitripennis |
NV18586-PA |
| H. sapiens |
ENSP00000428921 |
| C. quinquefasciatus |
CPIJ006042 |
| D. plexippus |
DPOGS204301PA |
| H. melpomene |
HMEL015167-PA |
| A. gambiae |
AGAP002986 |
| P. humanus |
PHUM373950-PA |
| H. sapiens |
ENSP00000314067 |
| H. sapiens |
ENSP00000361077 |
| S. invicta |
SI2.2.0_10373 |
| A. aegypti |
AAEL000489 |
| M. musculus |
ENSMUSG00000030774 |
| H. sapiens |
ENSP00000348696 |
| A. aegypti |
AAEL002594 |
| H. sapiens |
ENSP00000278568 |
| H. sapiens |
ENSP00000353864 |
| H. sapiens |
ENSP00000361080 |
| A. mellifera |
GB13173-PA |
| T. castaneum |
TC010914 |
| H. sapiens |
ENSP00000401982 |
| T. castaneum |
TC002075 |
| A. mellifera |
GB18379-PA |
| P. humanus |
PHUM310720-PA |