MidgeBase gene description page [Pn.01868]
Outline
| Gene ID | Pn.01868 |
| Type | Protein coding gene |
| Scaffold | PnScaf1640 |
| Start | 9293 |
| End | 13035 |
| Direction | + |
Sequence
Transcript: 1587 (bp)
ATGAATGTACATAAACGATGCGAGGAGAGCGTACCAAATTTATGTGGATGCGATCACACGGAGCGTCGTGGAAGAATCAACCTAAACATCACTTGCGTTGCCAATAAATTATCGATAGAAGTTAAGGAAGGACGTAATCTCATTCCCATGGACCCGAACGGCTTGAGCGATCCTTACGTGAAGATAAAGCTCATCCCCGACTCGGACTCGGTCAAGAAGAAAACGAAAACCATAAAGGCGACACTCAATCCGGTGTGGAATGAAACACTTGTGTTCGATTTAAAGCCAGAGGACAAAGATCGACGCATCTTGATAGAGGTCTGGGATTGGGATAGAACAAGTCGCAATGACTTTATGGGCTCGCTATCGTTCGGCATAAGCGAGATTATAAAGATGCCGGCAAAGGGATGGTTCAAACTGTTAACAGCCGAGGAAGGTGAATTCTACAATGTGCCAGTGCCGAGCGAGGACGGACCCGATTTGGCCCAATTAAAGATACAAATGCGCAAAACTTCCATCACAAAAAAGGCGCCCGTCATTACCGATAAGGATGTGCCACACAACATGGGCAAGAAGGACGTCATCCGAGCGACGGACTTCAACTTCCTCATGGTCCTCGGCAAGGGCTCCTTTGGCAAGGTGATGCTCGCCGAACGCAAGGGCACCGACGAGCTCTACGCCATCAAGATCCTCAAGAAGGACATCATCATTCAGGACGATGACGTCGAGTGCACGATGGTCGAGAAGCGCGTGCTGGCGCAGTCGGGAAAGCCGCCCTTCCTCGTCCAGCTGCACTCATGCTTCCAGACCATGGACCGCTTGTACTTTGTCATGGAGTACGTAAATGGCGGCGATTTAATGTTTCAAATTCAACAGTGTGGCAAATTCAAGGAACCTGTTGCTGTATTCTATGCAGCCGAAATCGCCATCGGATTGTTCTTCTTGCACACGTGCGGAATCATTTATCGTGATTTGAAGCTGGATAACGTGCTGCTCGACCAAGATGGCCACATCAAAATAGCCGATTTCGGAATGTGCAAGGAGAACATCACGAACGATAAGACAACAAAGACCTTCTGCGGAACGCCCGATTACATTGCCCCAGAAATCATCCTGTACCAGCCGTACGGAAAGAGCGTGGACTGGTGGGCATATGGTGTGCTTCTGTACGAGATGCTCGTCGGACAGCCGCCCTTCGATGGCGAAGATGAGGAGGAGCTGTTTGCTGCCATCACGGACCACAACGTGTCGTATCCGAAAGGTCTGAGTAAAGAGGCGAAGGACGTTTGCAAAGGGTTCTTGACAAAGAATCCGCAAAAGCGATTGGGTTGTGGCGCAAACGGAGAGGACGATGTCAGAAATCACAGCTTCTTCCGTCGCATCGATTGGGAGAAAATCGAGAACCGTGAAGTTCAACCGCCCTTCAAACCGAAAATTAAACATCGCAAGGACGTCTCGAACTTTGATCGCCAATTTACTTCAGAAAAGACGGATCTGACGCCAACCGACAAATTGTTCATGATGAATTTGGATCAAACGGAATTCAACGGATTTTCCTATTTGAATCCCGAATTTGTTCAGCATATT
Protein: 529 (aa)
MNVHKRCEESVPNLCGCDHTERRGRINLNITCVANKLSIEVKEGRNLIPMDPNGLSDPYVKIKLIPDSDSVKKKTKTIKATLNPVWNETLVFDLKPEDKDRRILIEVWDWDRTSRNDFMGSLSFGISEIIKMPAKGWFKLLTAEEGEFYNVPVPSEDGPDLAQLKIQMRKTSITKKAPVITDKDVPHNMGKKDVIRATDFNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDIIIQDDDVECTMVEKRVLAQSGKPPFLVQLHSCFQTMDRLYFVMEYVNGGDLMFQIQQCGKFKEPVAVFYAAEIAIGLFFLHTCGIIYRDLKLDNVLLDQDGHIKIADFGMCKENITNDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKGLSKEAKDVCKGFLTKNPQKRLGCGANGEDDVRNHSFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDRQFTSEKTDLTPTDKLFMMNLDQTEFNGFSYLNPEFVQHI
| Type | Start | End | Length |
| CDS |
9293 |
9413 |
121 |
| CDS |
9619 |
9628 |
10 |
| CDS |
9927 |
10070 |
144 |
| CDS |
10177 |
10219 |
43 |
| CDS |
10666 |
10704 |
39 |
| CDS |
10884 |
11363 |
480 |
| CDS |
11465 |
11532 |
68 |
| CDS |
11981 |
12096 |
116 |
| CDS |
12172 |
12255 |
84 |
| CDS |
12346 |
12536 |
191 |
| CDS |
12618 |
12758 |
141 |
| CDS |
12883 |
13032 |
150 |
| intron |
9414 |
9618 |
205 |
| intron |
9629 |
9926 |
298 |
| intron |
10071 |
10176 |
106 |
| intron |
10220 |
10665 |
446 |
| intron |
10705 |
10883 |
179 |
| intron |
11364 |
11464 |
101 |
| intron |
11533 |
11980 |
448 |
| intron |
12097 |
12171 |
75 |
| intron |
12256 |
12345 |
90 |
| intron |
12537 |
12617 |
81 |
| intron |
12759 |
12882 |
124 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001652409 |
protein kinase c [Aedes aegypti] gb|EAT47787.1| protein kinase c [Aedes aegypti] |
0.0 |
| InterPro |
IPR017441 |
Protein kinase, ATP binding site |
|
| InterPro |
IPR002290 |
Serine/threonine- / dual-specificity protein kinase, catalytic domain |
|
| InterPro |
IPR008973 |
C2 calcium/lipid-binding domain, CaLB |
|
| InterPro |
IPR017892 |
Protein kinase, C-terminal |
|
| InterPro |
IPR011009 |
Protein kinase-like domain |
|
| InterPro |
IPR008271 |
Serine/threonine-protein kinase, active site |
|
| InterPro |
IPR000961 |
AGC-kinase, C-terminal |
|
| InterPro |
IPR000719 |
Protein kinase, catalytic domain |
|
| InterPro |
IPR018029 |
C2 membrane targeting protein |
|
| InterPro |
IPR020477 |
C2 domain |
|
| InterPro |
IPR020635 |
Tyrosine-protein kinase, catalytic domain |
|
| InterPro |
IPR000008 |
C2 calcium-dependent membrane targeting |
|
| Gene Ontology(BP) |
GO:0006468 |
protein phosphorylation |
|
| Gene Ontology(MF) |
GO:0004713 |
protein tyrosine kinase activity |
|
| Gene Ontology(MF) |
GO:0005515 |
protein binding |
|
| Gene Ontology(MF) |
GO:0004674 |
protein serine/threonine kinase activity |
|
| Gene Ontology(MF) |
GO:0005524 |
ATP binding |
|
| Gene Ontology(MF) |
GO:0004672 |
protein kinase activity |
|
| Gene Ontology(MF) |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
|
| Pfam |
PF00069.20 |
Protein kinase domain |
7.6e-67 |
| Pfam |
PF06293.9 |
Lipopolysaccharide kinase (Kdo/WaaP) family |
0.17 |
| Pfam |
PF00130.17 |
Phorbol esters/diacylglycerol binding domain (C1 domain) |
0.15 |
| Pfam |
PF00433.19 |
Protein kinase C terminal domain |
8.9e-10 |
| Pfam |
PF07714.12 |
Protein tyrosine kinase |
3.8e-39 |
| Pfam |
PF00168.25 |
C2 domain |
1.4e-26 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
| Gene ID |
| Pn.08943 |
| Pn.16318 |
Orthologous genes
| Species |
Gene ID |
| H. sapiens |
ENSP00000408695 |
| H. sapiens |
ENSP00000263431 |
| A. aegypti |
AAEL000810 |
| M. musculus |
ENSMUSG00000021108 |
| H. sapiens |
ENSP00000318315 |
| H. melpomene |
HMEL004485-PA |
| C. quinquefasciatus |
CPIJ005701 |
| B. mori |
BGIBMGA000779-TA |
| H. sapiens |
ENSP00000380363 |
| H. sapiens |
ENSP00000438090 |
| T. castaneum |
TC008637 |
| H. melpomene |
HMEL012606-PA |
| D. melanogaster |
FBgn0004784 |
| H. sapiens |
ENSP00000440541 |
| P. humanus |
PHUM544690-PA |
| H. sapiens |
ENSP00000378217 |
| D. plexippus |
DPOGS206317PA |
| H. sapiens |
ENSP00000263125 |
| N. vitripennis |
NV12122-PA |
| A. aegypti |
AAEL009466 |
| A. gambiae |
AGAP012252 |
| M. musculus |
ENSMUSG00000021948 |
| S. invicta |
SI2.2.0_10533 |
| M. musculus |
ENSMUSG00000026778 |
| D. melanogaster |
FBgn0003091 |
| D. plexippus |
DPOGS212831PA |
| C. quinquefasciatus |
CPIJ019407 |
| S. invicta |
SI2.2.0_80358 |
| T. castaneum |
TC012107 |
| A. gambiae |
AGAP000418 |
| H. sapiens |
ENSP00000441752 |
| D. melanogaster |
FBgn0259680 |
| A. gambiae |
AGAP002748 |
| S. invicta |
SI2.2.0_08258 |
| H. sapiens |
ENSP00000450981 |
| H. melpomene |
HMEL009727-PA |
| B. mori |
BGIBMGA014073-TA |
| H. sapiens |
ENSP00000329127 |
| A. mellifera |
GB17972-PA |
| B. mori |
BGIBMGA014132-TA |
| H. sapiens |
ENSP00000331602 |
| P. humanus |
PHUM528520-PA |
| H. sapiens |
ENSP00000306124 |
| H. sapiens |
ENSP00000462087 |
| N. vitripennis |
NV14251-PA |
| P. humanus |
PHUM513980-PA |
| P. vanderplanki |
Pv.01860 |
| P. vanderplanki |
Pv.08166 |
| H. sapiens |
ENSP00000305355 |
| C. quinquefasciatus |
CPIJ020037 |
| T. castaneum |
TC008638 |
| N. vitripennis |
NV16050-PA |
| A. aegypti |
AAEL001108 |
| A. mellifera |
GB13673-PA |
| M. musculus |
ENSMUSG00000078816 |
| M. musculus |
ENSMUSG00000050965 |
| P. vanderplanki |
Pv.07869 |
| H. sapiens |
ENSP00000380361 |
| M. musculus |
ENSMUSG00000045038 |
| D. plexippus |
DPOGS207594PA |
| H. sapiens |
ENSP00000443493 |
| M. musculus |
ENSMUSG00000052889 |
| T. castaneum |
TC003019 |
| D. melanogaster |
FBgn0003093 |