MidgeBase gene description page [Pn.01673]
Outline
| Gene ID | Pn.01673 |
| Type | Protein coding gene |
| Scaffold | PnScaf1507 |
| Start | 38425 |
| End | 42012 |
| Direction | + |
Sequence
Transcript: 2829 (bp)
ATGAAAGTGAAGAAAATTGCTTTACTATTTCTCGCGTTTGCAATCGGCAGCGTTGAGTTGAGAACTCCGTCATACCTCGCGCGAAAGCTTAACCTCCAAGAATCCGGCTTAAATGCCGCTAAGCAATCCTCCTACGTGACTCAAGCCGACGCCATCAGCTATCGTTTGCCAAACAACACGCGTCCATTACATTATGACATTCATGTGACAACTCACATCCACGAGGAAAAATTTGAATTTAGCGGTCATGTGATTGTGGAATTCAGAGTTCTCAGCGCGCCACTCAATGAGATCACGCTTCACATGAAAGGCTTGGAGAATCTGAAAGTGAATTTGTGGAACTCGAGTCTCATTGAGAGCGATGTGCATTACGATCACGATGAGGTCACTGACTTTCTCACAGTCAAGCCGAGGAGCGATTTGGCGCTCAATGGAACCTACAAGCTCGAATTCACGTACGACGGCGAGTTGAGAGACGACAACCTCGGCTTCTACCGATCCTCGTATCTCGACGAGAATGACAAGACAGTTTGGCTGGCGACCACACAGTTCGAAAATGTGGAAGCTCGAAGCGCCTTCCCATGTTACGATGAGACACACATTCGAACACGTTTTAAGCTCATGATAACGTACGGAGCGAATTACACGGCTGTCGCCAATATGCCGGCCGTTAACACCGCTCCATCTGCTGAGCTCGACGGCTATTTGACGACGGAGTTCGAGGAGGCCCCAGAAATCCACACATATCTGATTGCCTTCATTATCTCGGACTTTAAGTATGTGGCGCGAGAAAACCAGCGAGCATATGCAAAACCAGGCGCAGTCGACAAGGGCGAGGCTGATCTCGCCCTTAAATATGGCCTGGAAATCATCCCCCGGTTTGAGGAGTATTTGGGCGTCGATTATTTTGTTCCCAAAATGGATCAGTTTGCGCTGCCCGACTTTGACGCCGGCGCCATGGAGAACTTTGGGCTTGTGACGTACAGAGAGGAGTATTTGCTGCACAACAGCTCCATCGACACGACGCAGCAGAAAGAAAATGTTTTGACAATCGTCAGTCATGAGTTCGCCACACATTTTATTGCAGGCGACTTGGTTGGACCCGAGTGGTGGAGTGTTTTGTGGCTAAACGAAGGTTTCGCGACTCTTTACGAGTTTTATCTCGTCAGTCTGATTTACGACAACGATCGCTTGATGGACTCGTTTATATTGAACGCAGTGCATCCCGCACTTGAGTACGATGGAGATGACGTCCGTCCGATGACTCACTATGTCGAGAGCCCGGAAAATATTGACGACCTTTTCGACTACATCGCCTACGAAAAGGCTGGAAGTGTGCTGCGCATGATGCAGAACACGGTCGGTGACGACGTTTGGAGGAAGGGCCTGAACTACTATCTCAAGGACCGCTCGCTGAAGGCGGCCAACCCAGACGATCTCCATCGAAACCTTCAACTCGCACTCAACGAACACGGTCTCGAAGATCTTGACATTGCAAAAATCATGTTATCATGGGAGACACAATCAGGTTATCCGGTCGTTAAAGTCACAAAAAATGCTGACAACATTACGTTCACTCAGGAGCGCTTTCTGTACAAAGAGACGGCCGACTCCTCGCTCTGGTATGTGCCAATCAACTTCGTCACTGCATCGGACCCGGTCGTCATCACCACCAAGCCCGACCTGTGGCTGAACAGAGAAAAATCGACGACGGTGTTGAGGAGAGACGCGACGAGGAATTGGAGCGAAGACGATTGGATTATCGCGAACCTACAGCAGGGCTACTACTATCGTGTGAACTACGACGACGAGCTGTGGCAACTGATCATTGAGCAACTCGACGCGTGTCACACGAAAATTGACTTGCGCAGCCGCGGTCAGCTTATTGACGACTCGCTGAACTTGGCGCGCGCTGGAAAAGTCTCTTACGACATCGCGCTCAGTGTCATAAGGCATCTCAAGCGAGAGACCGACTATTTACCATGGGCGGCGGCAAACGGCGACTTGCTCCTTATCAATCGCTGGCTGAGCGGCCTCCCGATGCACGAAAAGTACCGAAAATTCGTTCTGAACCTCGTTAAGCCATTGTACGAGCACGTGGGCTTCGAAATTATGCCGAACGAGCACAAATTTAACCGCTACTCGCGCAGACTCGCAATCAATCTCGCGTGCCAATTTGGCCACGAGTCGTGCGTCGCGACCGCAAAAGACAAATTGGGCGACGCGAACATCCATCCGGACATGCAGGAAGCTATTTACGCGAACGGCCTGCGAGAGGCCAACGAAACCACGTATAACGGGACGATCGAGCTGATGCTGAATTTGAAGTACCAAGCGCAGAGAACGCTGCTGATTCGAGCACTTGCCGGTGCGCAGAACGAGGCGAACTTGATGAGGCTCCTGATGTTGGCGGTGTCGTCGGACGAGCCGAGAATTCGACTGCAAGAGCGCTACAGAATCTTCAGCTCGTGGACGAATGCAGGCAGTGTCGGCGTGAAGGTGGCCATTGAGTTTGTTCGCGAAAAATACGAGGACATCAACAAAATCTCGTCGTCACTCGTGCGCTCGATTCTCAACAATGCCGCTTCTTACATCTCGGCCGATGATCTTGCGACACAATTTACCGAGCTACTTGATTTCTTGATAGACAAAAAAGTGATTGAGGAGAGCCACAAAAGTGACTATCTCAGCACGGTGAATGCCACGAAGACGTGGCAAGATAAAAATGTTAAAGTTATTGAAGAGTGGCTCGACCGTAATGGAGCAAGTTCAATCATCATCTCAACGACGCTCGTCTTTGTATTTTCCGCAGTAATGAAACTCTTTTTC
Protein: 943 (aa)
MKVKKIALLFLAFAIGSVELRTPSYLARKLNLQESGLNAAKQSSYVTQADAISYRLPNNTRPLHYDIHVTTHIHEEKFEFSGHVIVEFRVLSAPLNEITLHMKGLENLKVNLWNSSLIESDVHYDHDEVTDFLTVKPRSDLALNGTYKLEFTYDGELRDDNLGFYRSSYLDENDKTVWLATTQFENVEARSAFPCYDETHIRTRFKLMITYGANYTAVANMPAVNTAPSAELDGYLTTEFEEAPEIHTYLIAFIISDFKYVARENQRAYAKPGAVDKGEADLALKYGLEIIPRFEEYLGVDYFVPKMDQFALPDFDAGAMENFGLVTYREEYLLHNSSIDTTQQKENVLTIVSHEFATHFIAGDLVGPEWWSVLWLNEGFATLYEFYLVSLIYDNDRLMDSFILNAVHPALEYDGDDVRPMTHYVESPENIDDLFDYIAYEKAGSVLRMMQNTVGDDVWRKGLNYYLKDRSLKAANPDDLHRNLQLALNEHGLEDLDIAKIMLSWETQSGYPVVKVTKNADNITFTQERFLYKETADSSLWYVPINFVTASDPVVITTKPDLWLNREKSTTVLRRDATRNWSEDDWIIANLQQGYYYRVNYDDELWQLIIEQLDACHTKIDLRSRGQLIDDSLNLARAGKVSYDIALSVIRHLKRETDYLPWAAANGDLLLINRWLSGLPMHEKYRKFVLNLVKPLYEHVGFEIMPNEHKFNRYSRRLAINLACQFGHESCVATAKDKLGDANIHPDMQEAIYANGLREANETTYNGTIELMLNLKYQAQRTLLIRALAGAQNEANLMRLLMLAVSSDEPRIRLQERYRIFSSWTNAGSVGVKVAIEFVREKYEDINKISSSLVRSILNNAASYISADDLATQFTELLDFLIDKKVIEESHKSDYLSTVNATKTWQDKNVKVIEEWLDRNGASSIIISTTLVFVFSAVMKLFF
| Type | Start | End | Length |
| CDS |
38425 |
39008 |
584 |
| CDS |
39090 |
39462 |
373 |
| CDS |
39519 |
39632 |
114 |
| CDS |
39757 |
39820 |
64 |
| CDS |
39896 |
40087 |
192 |
| CDS |
40218 |
40882 |
665 |
| CDS |
41173 |
42009 |
837 |
| intron |
39009 |
39089 |
81 |
| intron |
39463 |
39518 |
56 |
| intron |
39633 |
39756 |
124 |
| intron |
39821 |
39895 |
75 |
| intron |
40088 |
40217 |
130 |
| intron |
40883 |
41172 |
290 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001662888 |
protease m1 zinc metalloprotease [Aedes aegypti] gb|EAT35030.1| protease m1 zinc metalloprotease [Aedes aegypti] |
1e-177 |
| InterPro |
IPR001930 |
Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase |
|
| InterPro |
IPR014782 |
Peptidase M1, membrane alanine aminopeptidase, N-terminal |
|
| InterPro |
IPR015569 |
Peptidase M1, aminopeptidase N |
|
| InterPro |
IPR024571 |
Domain of unknown function DUF3358 |
|
| Gene Ontology(BP) |
GO:0006508 |
proteolysis |
|
| Gene Ontology(MF) |
GO:0008237 |
metallopeptidase activity |
|
| Gene Ontology(MF) |
GO:0008270 |
zinc ion binding |
|
| Pfam |
PF11838.3 |
Domain of unknown function (DUF3358) |
2.8e-28 |
| Pfam |
PF01433.15 |
Peptidase family M1 |
1.5e-100 |
| Pfam |
PF00335.15 |
Tetraspanin family |
0.22 |
| Pfam |
PF13485.1 |
Peptidase MA superfamily |
1.3e-13 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
| Gene ID |
| Pn.12206 |
| Pn.14973 |
| Pn.15310 |
| Pn.12462 |
| Pn.15342 |
| Pn.15343 |
| Pn.05520 |
| Pn.04002 |
| Pn.16153 |
| Pn.02786 |
| Pn.02787 |
Orthologous genes
| Species |
Gene ID |
| P. vanderplanki |
Pv.00665 |
| D. melanogaster |
FBgn0038136 |
| D. melanogaster |
FBgn0052473 |
| A. mellifera |
GB14689-PA |
| A. aegypti |
AAEL008155 |
| A. mellifera |
GB14456-PA |
| A. gambiae |
AGAP012984 |
| N. vitripennis |
NV15818-PA |
| A. aegypti |
AAEL011292 |
| C. quinquefasciatus |
CPIJ801487 |
| H. sapiens |
ENSP00000414374 |
| C. quinquefasciatus |
CPIJ008387 |
| A. gambiae |
AGAP002508 |
| M. musculus |
ENSMUSG00000023845 |
| M. musculus |
ENSMUSG00000021583 |
| A. mellifera |
GB17753-PA |
| N. vitripennis |
NV13692-PA |
| A. aegypti |
AAEL012779 |
| H. sapiens |
ENSP00000369235 |
| S. invicta |
SI2.2.0_03105 |
| A. aegypti |
AAEL015248 |
| P. vanderplanki |
Pv.14161 |
| P. vanderplanki |
Pv.00340 |
| P. humanus |
PHUM128360-PA |
| H. sapiens |
ENSP00000421849 |
| A. gambiae |
AGAP000885 |
| D. melanogaster |
FBgn0051445 |
| H. sapiens |
ENSP00000265162 |
| S. invicta |
SI2.2.0_00152 |
| M. musculus |
ENSMUSG00000050663 |
| H. sapiens |
ENSP00000231368 |
| P. vanderplanki |
Pv.11102 |
| P. vanderplanki |
Pv.05976 |
| D. melanogaster |
FBgn0046253 |
| N. vitripennis |
NV10584-PA |
| D. plexippus |
DPOGS200549PA |
| N. vitripennis |
NV10583-PA |
| S. invicta |
SI2.2.0_00292 |
| D. melanogaster |
FBgn0051233 |
| H. sapiens |
ENSP00000400376 |
| B. mori |
BGIBMGA010763-TA |
| N. vitripennis |
NV12289-PA |
| A. aegypti |
AAEL005806 |
| T. castaneum |
TC004952 |
| T. castaneum |
TC004557 |
| A. aegypti |
AAEL011291 |
| T. castaneum |
TC001362 |
| S. invicta |
SI2.2.0_05573 |
| P. vanderplanki |
Pv.11596 |
| A. aegypti |
AAEL007201 |
| B. mori |
BGIBMGA008066-TA |
| D. plexippus |
DPOGS208533PA |
| H. sapiens |
ENSP00000296754 |
| H. melpomene |
HMEL015730-PA |
| P. vanderplanki |
Pv.09750 |
| C. quinquefasciatus |
CPIJ011103 |
| A. aegypti |
AAEL008162 |
| A. aegypti |
AAEL012783 |
| H. sapiens |
ENSP00000423604 |
| H. melpomene |
HMEL016873-PA |
| A. gambiae |
AGAP013150 |
| P. humanus |
PHUM411940-PA |
| S. invicta |
SI2.2.0_01532 |
| D. plexippus |
DPOGS209792PA |
| T. castaneum |
TC004641 |
| C. quinquefasciatus |
CPIJ801489 |
| T. castaneum |
TC004830 |
| H. sapiens |
ENSP00000350541 |
| D. melanogaster |
FBgn0038135 |
| C. quinquefasciatus |
CPIJ801488 |
| H. sapiens |
ENSP00000300060 |
| D. melanogaster |
FBgn0039640 |
| P. humanus |
PHUM412200-PA |
| M. musculus |
ENSMUSG00000028024 |
| S. invicta |
SI2.2.0_04503 |
| D. plexippus |
DPOGS209834PA |
| P. vanderplanki |
Pv.00339 |
| P. vanderplanki |
Pv.00666 |
| C. quinquefasciatus |
CPIJ008388 |
| D. melanogaster |
FBgn0263236 |
| A. gambiae |
AGAP001881 |
| H. sapiens |
ENSP00000261180 |
| A. mellifera |
GB11149-PA |
| A. mellifera |
GB18549-PA |
| D. melanogaster |
FBgn0015541 |
| H. sapiens |
ENSP00000406304 |
| M. musculus |
ENSMUSG00000024481 |
| B. mori |
BGIBMGA010764-TA |
| N. vitripennis |
NV12290-PA |
| B. mori |
BGIBMGA008017-TA |
| A. gambiae |
AGAP004809 |
| H. sapiens |
ENSP00000421175 |
| A. aegypti |
AAEL008158 |
| D. plexippus |
DPOGS200548PA |
| N. vitripennis |
NV16959-PA |
| A. mellifera |
GB16506-PA |
| P. vanderplanki |
Pv.01088 |
| C. quinquefasciatus |
CPIJ004060 |
| C. quinquefasciatus |
CPIJ012471 |
| A. mellifera |
GB10441-PA |
| B. mori |
BGIBMGA010679-TA |
| P. humanus |
PHUM411950-PA |
| S. invicta |
SI2.2.0_80061 |
| N. vitripennis |
NV14979-PA |
| A. gambiae |
AGAP013001 |
| H. melpomene |
HMEL004822-PA |
| H. melpomene |
HMEL004351-PA |
| H. melpomene |
HMEL008414-PA |
| H. sapiens |
ENSP00000379117 |
| D. melanogaster |
FBgn0039656 |
| T. castaneum |
TC016254 |
| P. humanus |
PHUM512710-PA |
| A. aegypti |
AAEL012099 |
| A. aegypti |
AAEL008163 |
| A. gambiae |
AGAP013155 |
| P. vanderplanki |
Pv.00663 |
| M. musculus |
ENSMUSG00000039062 |
| C. quinquefasciatus |
CPIJ006295 |
| P. vanderplanki |
Pv.14573 |
| D. melanogaster |
FBgn0051343 |
| A. gambiae |
AGAP003077 |
| H. sapiens |
ENSP00000425758 |
| A. aegypti |
AAEL012217 |
| D. melanogaster |
FBgn0030223 |
| A. aegypti |
AAEL012778 |
| A. aegypti |
AAEL009108 |
| P. vanderplanki |
Pv.11953 |
| N. vitripennis |
NV15249-PA |
| C. quinquefasciatus |
CPIJ014660 |