MidgeBase gene description page [Pn.01050]
Outline
| Gene ID | Pn.01050 |
| Type | Protein coding gene |
| Scaffold | PnScaf1040 |
| Start | 28728 |
| End | 30879 |
| Direction | + |
Sequence
Transcript: 1968 (bp)
ATGGCGTGCCCATTCGTTCAAAGGAAGCCAGTCGATTCATTCAAGCGACAGCAATCAACGGTTGCTGACTTTGATCTCACCCAGGACGACAACTCTCTGACACTGAAGCACATCAACAGTGCTCTGCAGCTTTTGACTGCACCCAGCAACGAAGCCATCAATGAAGCACTCTTCTCGCTCACCGAGAAGCACAGCGAAAAATTTCCCGGGCTAGCAAAACTCGCCGATGAAAAAAAGAACATTTCGTCATTTCCGAATTATGACTACTTGGCTGACATACAAACGGCATTAATGGAACTTGATGAGGGAACGGCAATCGATATCCTAATTTTATTGGGCGAGGAATTAATTGAACAAAATTGTAAAGGAATTATCGAGCGAGCTTTTATGAGTCTCGGTGGAAGTATGAAGGAGTTCTTCTCGAGTCTCGACGGCGTCTATGATGTATTGAAGTTGCAAGAGGAAGACTTGACTGATGCGGGTTTCATCTGTGCATCGGAGAATGAGCTCATTTTTACATCGGAACGTGCGTGTGTCGCATATGTTTTGCTTGGAATTCTCAAGCGATTATCGAAGAAACTCTATGGAGAACACTGTGAAATTAATATGGAAATCATTGAAGGGAGTATTCAACGTTTTCGTTATCTCTTCCGAATCTTGGACGAGAAAAAACCCGAGGTTCAAGTACGTGAACTTTCCTCAGATCCAAAGGACTTGCAGATGAAAAATTCGACTTTTTGCAAAATGTTCCCTTGGCACTTCATTATCGACGAGAATTTAAATTTGTTGCAAATCGGAGAGGCTTTCAGTAAGCTCTTCAAGAGCTACTTGAACACAACCCGAGCAGTCACCAACTTTTTCCGCTTTAAACGTCCAGTTGGTCTGAAGCTTGAATTCAGTGAAATAGCGAAGCGAACAAACACACCGTTTCTGTTGTCACTTCGCTCTCCACGACCCGATTTCGTTGCCAAGGGTCTCGAAATTAAGGGTCAAATGGTCCTCTGCAAGAATGCAAAAAAAAATACTCTCATGTTCCTCGGCTCGCCATTTATAGACGGTCTAGAAGGACTAACTTGCAACGGACTTTTCTTGTCCGATATTCCAATTTTCGATGCGACAAGAGAGGTCATTCTCGTCGGTGAGCAAGCGCGTGCTCAAGACGGTCTTAAGCTTCGCATGGCCAAGTTGAAGAAGGAGGTCGAAGAGGGTCACGAAGCTGTATCGGAAGAGAGAAAGAAAAATGTTTCTTTACTTCAGCTCATTTTCCCCGATGAAATTGCAGAAAAGCTATGGCTAGGCAAGCCAGTCGACGCCCAAACGTTCGAAAATGTTACTATGCTCTTCTCCGACATTGTCGGTTTCACAGGAATTTGCTCCACCGCAACTCCACTTCAGGTCATCTCCATGCTAGAGAGCCTTTACAAGGTGTTTGACGAGTACTGTGGCATATTTGATGTATACAAAATCGAGACCGTAGGCGACGCATACTGCTTGGCAACAGGTTTGGAGGGTAGAAACAAAAACAGCCTTTACAACGCTTCGAAAGTCGCATTAATGGCCATGAAGATGATTGAAACCTGCTCGAAGCATGTCACTCATTCTGGAAAGAATATTCAGATGAGAATTGGCTTACACACGGCAGTTTGTCTCGGTGGAGTTGTTGGTCGGAAGATGCCACGCTTCTGTTTGATGGGTCACTCGGTCACCATCGCTAATAAGTTCGAATCGGGCAGCGAAGCTGGAAAAATTAATATTTCAAGCAAGACTAAAGAAGCTCTCCAAATGGTACCCGAATTCCAATTTGAATTTACCGAGCGCGACCCGTCCTGTTTGCCTAAAGAGTACCAAGCAGCTCCGGGTGAAACCTGTTATTTTTTGGATGGTTTCACTCACACAGCCATTGACAAAAATGCAGAGGTTAATGCACATATTGACGCCGCCATTAAGCAAATTCAATCAGAATCAAAT
Protein: 656 (aa)
MACPFVQRKPVDSFKRQQSTVADFDLTQDDNSLTLKHINSALQLLTAPSNEAINEALFSLTEKHSEKFPGLAKLADEKKNISSFPNYDYLADIQTALMELDEGTAIDILILLGEELIEQNCKGIIERAFMSLGGSMKEFFSSLDGVYDVLKLQEEDLTDAGFICASENELIFTSERACVAYVLLGILKRLSKKLYGEHCEINMEIIEGSIQRFRYLFRILDEKKPEVQVRELSSDPKDLQMKNSTFCKMFPWHFIIDENLNLLQIGEAFSKLFKSYLNTTRAVTNFFRFKRPVGLKLEFSEIAKRTNTPFLLSLRSPRPDFVAKGLEIKGQMVLCKNAKKNTLMFLGSPFIDGLEGLTCNGLFLSDIPIFDATREVILVGEQARAQDGLKLRMAKLKKEVEEGHEAVSEERKKNVSLLQLIFPDEIAEKLWLGKPVDAQTFENVTMLFSDIVGFTGICSTATPLQVISMLESLYKVFDEYCGIFDVYKIETVGDAYCLATGLEGRNKNSLYNASKVALMAMKMIETCSKHVTHSGKNIQMRIGLHTAVCLGGVVGRKMPRFCLMGHSVTIANKFESGSEAGKINISSKTKEALQMVPEFQFEFTERDPSCLPKEYQAAPGETCYFLDGFTHTAIDKNAEVNAHIDAAIKQIQSESN
| Type | Start | End | Length |
| CDS |
28728 |
28948 |
221 |
| CDS |
29017 |
30567 |
1551 |
| CDS |
30625 |
30692 |
68 |
| CDS |
30749 |
30876 |
128 |
| intron |
28949 |
29016 |
68 |
| intron |
30568 |
30624 |
57 |
| intron |
30693 |
30748 |
56 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001659294 |
guanylatte cyclase alpha 1 subunit [Aedes aegypti] gb|EAT47419.1| guanylatte cyclase alpha 1 subunit [Aedes aegypti] |
0.0 |
| InterPro |
IPR011644 |
Heme-NO binding |
|
| InterPro |
IPR001054 |
Adenylyl cyclase class-3/4/guanylyl cyclase |
|
| InterPro |
IPR024096 |
NO signalling/Golgi transport ligand-binding domain |
|
| InterPro |
IPR011645 |
Haem NO binding associated |
|
| Gene Ontology(BP) |
GO:0006182 |
cGMP biosynthetic process |
|
| Gene Ontology(BP) |
GO:0009190 |
cyclic nucleotide biosynthetic process |
|
| Gene Ontology(BP) |
GO:0035556 |
intracellular signal transduction |
|
| Gene Ontology(MF) |
GO:0020037 |
heme binding |
|
| Gene Ontology(MF) |
GO:0016849 |
phosphorus-oxygen lyase activity |
|
| Gene Ontology(MF) |
GO:0004383 |
guanylate cyclase activity |
|
| Pfam |
PF07700.10 |
Heme NO binding |
8.9e-08 |
| Pfam |
PF07701.9 |
Heme NO binding associated |
8.4e-54 |
| Pfam |
PF00211.15 |
Adenylate and Guanylate cyclase catalytic domain |
7.5e-51 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| C. quinquefasciatus |
CPIJ010180 |
| H. sapiens |
ENSP00000426968 |
| M. musculus |
ENSMUSG00000041624 |
| P. humanus |
PHUM588150-PA |
| H. sapiens |
ENSP00000426040 |
| H. melpomene |
HMEL004463-PA |
| A. gambiae |
AGAP000280 |
| H. sapiens |
ENSP00000421493 |
| H. sapiens |
ENSP00000344874 |
| H. sapiens |
ENSP00000377418 |
| N. vitripennis |
NV15836-PA |
| H. sapiens |
ENSP00000431245 |
| S. invicta |
SI2.2.0_08279 |
| A. aegypti |
AAEL001457 |
| B. mori |
BGIBMGA009300-TA |
| D. plexippus |
DPOGS215506PA |
| H. sapiens |
ENSP00000296518 |
| P. vanderplanki |
Pv.10317 |
| D. melanogaster |
FBgn0013972 |
| M. musculus |
ENSMUSG00000033910 |
| H. sapiens |
ENSP00000424361 |
| A. mellifera |
GB19367-PA |
| T. castaneum |
TC008018 |
| H. sapiens |
ENSP00000282249 |
| H. sapiens |
ENSP00000412201 |