MidgeBase gene description page [Pn.00761]
Outline
| Gene ID | Pn.00761 |
| Type | Protein coding gene |
| Scaffold | PnScaf791 |
| Start | 62078 |
| End | 64957 |
| Direction | + |
Sequence
Transcript: 2592 (bp)
ATGCCTCACGAACTGCTCACGAAAATCAAATCTTATCGCTCAACAATTGTTGAAGCAGTTCAGTGGACATTCGATGAGATCAATAGTGAGTCAGGCGAGCTGCACCACTTGGCCGCGTTCTTGGCTGACAAGAAGATCGAGCTGGTCATCAATCTCCCAATGCGAGGAGGCGGTGCGCGAAGAGTCTCGTCGTTCATGACGCACGGCTACCGAACACGCCGCTTAGCCGTCGACTACTCGATTCCGCTAGTGACCGACGTGAAGTGCACGAAGCTTCTGGTCGAGGCGATGCGACTTTCGGGACGCGCACCACCCATGAAAACGCACACCGACTGCATGACCAGCCGTCAAATGATTAAACTTCCTGGCTTTATCGATGTGCACGTGCATTTGCGCGAACCGGGAGCAACGCACAAGGAGGACTTCGCGTCGGGAACGTCAGCAGCATTGGCCGGCGGAATAACGCTCGTCTGCGCCATGCCAAACACAAACCCGGCCATCGTCAACCAGCAGACCTTCACGCTCTTCAAAGAGTGCGCGAAAGTCGGCGCTCGCTGCGACTACGCTCTCTTTGTCGGCGCCTCATCCGACAACTACCATCAGATTTGCGAGCTCGCGCCCGAGGCTGCGGCCCTCAAAATGTACTTAAACGAGACATTCACGACGCTGAAGCTCAATGACATGACCGTGTGGGAAAAACACTTGAGCAATTGGCCCAAGCATGCGCCATTGTGTGTGCACGCGGAGAGGCAAGCCACAGCTGCAATTATTCTGCTCGCGAACCTCATCGATCGTCCGATTCACGTGTGCCATGTGGCACGAAAGGAGGAGATTTTGATCATCAAGGCGGCCAAGGAGCGCGGCATGAAGATCACGTGCGAGGTCTGCCCGCACCACCTGTTTTTGTCTACGAAAGACTTGGGACGCATCGGAGGCGGTCGCGGCGAAGTTCGGCCGATCTTGTGCTCGCCCGAGGACCAGCAAGCGCTGTGGGACAACATGGACATCATCGACTGCTTCGCCACCGATCACGCGCCGCACACAATCGAAGAAAAGGACAGCGAGAAGCCGCCGCCAGGCTTCCCCGGTTTGGAGACGATTCTGCCGCTTCTCCTCACGGCAGTCAACGACGGCCGTCTCACGATGGACGATTTGATCAACAAGTTCTACAAGAACCCGCGAAAAATCTTCAACCTGCCCGAGCAGCATAACACCTACGTCGAGGTCGACATGGACGAGGAGTGGGTCATTCCGAACGAGCTGAGACACTCGAAGGCGCGTTGGACGCCGTTTGCCGGCATGAAGGTCAAGGGCTGCGTGTCGCGCGTCGTTTTGCGCGGCGAGGTCGCTTTCGTCGATGGCGAGGTTTTGGTCGAGCCGGGCTTCGGCCAGAACGTCCGTCAGTGGCGAAACCGAGTGATCGACGACGAGAAGTTGCTGAACGGATCGACCGAGAGAATCAACAGCTCGTTCGAGCACCTGGACGAGGAGCTGCAGGTGAAAATCCCCGACTCTACGACCTCGAAGTTGCCGAGCTACTACTCGGCTCTATCGCCGCTGCCGCGTTCGCGCCTTGACTCGGCCGGCAGCCAGCTCTACCGCGAATATTTCCCGGAAACTTTCGGCCGCTCCTATTCGAAGGCGATGACCGGCAAGAGCATTCTGAGCGTCGACATGTTCACGACGAAGGACCAGCTGCGCGACATCTTCGATCTCGCCAAATACTTCAAGGCGAGCATCCAGAAGAAGGGCCTGCTCGACGAGGTCCTCCGCGGCAAGGTGATGGCGTCGTGCTTCTACGAGGTCTCGACGCGAACGTGCTGCAGCTTCGCTGCCGCTATGCAGCGCCTCGGCGGCCGCGTCATCTACATGGACGAGACGAGTTCGTCGGTGAAGAAGGGCGAGACCTTGGAGGACTCGATCGCCGTCATGTCCGGCTACTCGGACGTCGTCGTCTTGCGTCATCCGGAGGTCGGAGCGATGGCACGTGCAGCGGACGTGTCGCAGAAACCGATCATAAATGCGGGCGACGGAGTCGGCGAGCATCCGACGCAAGCCCTTCTCGACGTCTTCACGATTCGCGAGGAGTTCGGCACCGTCAAGGGCCTCACCATCACGATGGTCGGCGACCTGAAGCACGGCCGCACAGTCCACTCGCTCGCGTGTCTGCTGACACTCTACGACGTGACAATCAACTACGTTTGTCCCGCTGCGCTGACAATGCCCGAAAAGGTCATCAAATTCGTCGCCTCGAAAGGAATTTCGCAGAACTTTTACAGTTCCCTTGACGAGGCGCTGCCGGAGACAGACGTTCTGTATATGACGCGCATTCAGAAAGAGCGCTTCGCGAGCGAGGAGGAATACAAGAGCACTTGCGGTCTGTACGTGGTTACGCCGAAACTGATGACACGCGCAAAGTCTAAAATGATTGTTATGCACCCGTTGCCGAGAGTTGATGAGATCGACAAGGCGTTCGACAATGACAAACGCGCCGCTTACTTTAGACAAGCCGAGTACGGAATGTACGTTCGCATGAGTATTCTCGCGATGGTGCTCGGTTTTGAGGGCATTCCGCAGAAAGCGGTGAGGAAA
Protein: 864 (aa)
MPHELLTKIKSYRSTIVEAVQWTFDEINSESGELHHLAAFLADKKIELVINLPMRGGGARRVSSFMTHGYRTRRLAVDYSIPLVTDVKCTKLLVEAMRLSGRAPPMKTHTDCMTSRQMIKLPGFIDVHVHLREPGATHKEDFASGTSAALAGGITLVCAMPNTNPAIVNQQTFTLFKECAKVGARCDYALFVGASSDNYHQICELAPEAAALKMYLNETFTTLKLNDMTVWEKHLSNWPKHAPLCVHAERQATAAIILLANLIDRPIHVCHVARKEEILIIKAAKERGMKITCEVCPHHLFLSTKDLGRIGGGRGEVRPILCSPEDQQALWDNMDIIDCFATDHAPHTIEEKDSEKPPPGFPGLETILPLLLTAVNDGRLTMDDLINKFYKNPRKIFNLPEQHNTYVEVDMDEEWVIPNELRHSKARWTPFAGMKVKGCVSRVVLRGEVAFVDGEVLVEPGFGQNVRQWRNRVIDDEKLLNGSTERINSSFEHLDEELQVKIPDSTTSKLPSYYSALSPLPRSRLDSAGSQLYREYFPETFGRSYSKAMTGKSILSVDMFTTKDQLRDIFDLAKYFKASIQKKGLLDEVLRGKVMASCFYEVSTRTCCSFAAAMQRLGGRVIYMDETSSSVKKGETLEDSIAVMSGYSDVVVLRHPEVGAMARAADVSQKPIINAGDGVGEHPTQALLDVFTIREEFGTVKGLTITMVGDLKHGRTVHSLACLLTLYDVTINYVCPAALTMPEKVIKFVASKGISQNFYSSLDEALPETDVLYMTRIQKERFASEEEYKSTCGLYVVTPKLMTRAKSKMIVMHPLPRVDEIDKAFDNDKRAAYFRQAEYGMYVRMSILAMVLGFEGIPQKAVRK
| Type | Start | End | Length |
| CDS |
62078 |
62125 |
48 |
| CDS |
62330 |
62463 |
134 |
| CDS |
62545 |
64954 |
2410 |
| intron |
62126 |
62329 |
204 |
| intron |
62464 |
62544 |
81 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_001660111 |
carbamoyl-phosphate synthase large chain [Aedes aegypti] gb|EAT38648.1| carbamoyl-phosphate synthase large chain [Aedes aegypti] |
0.0 |
| InterPro |
IPR006132 |
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding |
|
| InterPro |
IPR006680 |
Amidohydrolase 1 |
|
| InterPro |
IPR006131 |
Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain |
|
| InterPro |
IPR011607 |
Methylglyoxal synthase-like domain |
|
| InterPro |
IPR011059 |
Metal-dependent hydrolase, composite domain |
|
| InterPro |
IPR006130 |
Aspartate/ornithine carbamoyltransferase |
|
| InterPro |
IPR002195 |
Dihydroorotase, conserved site |
|
| InterPro |
IPR002082 |
Aspartate carbamoyltransferase, eukaryotic |
|
| Gene Ontology(BP) |
GO:0006520 |
cellular amino acid metabolic process |
|
| Gene Ontology(BP) |
GO:0006207 |
'de novo' pyrimidine base biosynthetic process |
|
| Gene Ontology(MF) |
GO:0016812 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
|
| Gene Ontology(MF) |
GO:0016787 |
hydrolase activity |
|
| Gene Ontology(MF) |
GO:0016597 |
amino acid binding |
|
| Gene Ontology(MF) |
GO:0016743 |
carboxyl- or carbamoyltransferase activity |
|
| Gene Ontology(MF) |
GO:0004070 |
aspartate carbamoyltransferase activity |
|
| Gene Ontology(MF) |
GO:0016810 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
|
| Pfam |
PF02729.16 |
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain |
1.4e-42 |
| Pfam |
PF13147.1 |
Amidohydrolase |
1.4e-13 |
| Pfam |
PF07969.6 |
Amidohydrolase family |
0.13 |
| Pfam |
PF00185.19 |
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain |
1.6e-40 |
| Pfam |
PF01979.15 |
Amidohydrolase family |
5.3e-12 |
| Pfam |
PF00252.13 |
Ribosomal protein L16p/L10e |
0.041 |
| Pfam |
PF13594.1 |
Amidohydrolase |
6.7e-06 |
| Pfam |
PF02142.17 |
MGS-like domain |
4.6e-07 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| A. gambiae |
AGAP000300 |
| A. mellifera |
GB16437-PA |
| P. vanderplanki |
Pv.15659 |
| H. melpomene |
HMEL012118-PA |
| P. humanus |
PHUM000420-PA |
| M. musculus |
ENSMUSG00000025991 |
| D. melanogaster |
FBgn0003189 |
| T. castaneum |
TC012392 |
| M. musculus |
ENSMUSG00000013629 |
| H. sapiens |
ENSP00000264705 |
| H. sapiens |
ENSP00000384510 |
| A. aegypti |
AAEL009475 |
| P. vanderplanki |
Pv.15661 |
| C. quinquefasciatus |
CPIJ007153 |
| H. sapiens |
ENSP00000406136 |
| S. invicta |
SI2.2.0_08333 |
| H. sapiens |
ENSP00000233072 |
| D. plexippus |
DPOGS205071PA |
| B. mori |
BGIBMGA006816-TA |
| A. aegypti |
AAEL009490 |
| H. sapiens |
ENSP00000402608 |
| N. vitripennis |
NV12337-PA |
| S. invicta |
SI2.2.0_03623 |