MidgeBase gene description page [Pn.00704]
Outline
| Gene ID | Pn.00704 |
| Type | Protein coding gene |
| Scaffold | PnScaf749 |
| Start | 27117 |
| End | 30109 |
| Direction | + |
Sequence
Transcript: 1323 (bp)
ATGGCATTTGCACTAAGTAAAATTGCTAAATGCATCAACAAAAATGCGTTTGTCACGCCATTGTCATCGGCCATGTCCTCAAAGAATTATTCTAGCGGCAGCCGCGTAGAAGTAGCTAAACCTGTTGTTGAAATGGACGGCGATGAAATGACTCGCATCATCTGGCAATTCATTAAGGATAAATTGATCTTCCCTTATGTCAAAGTTGAGTGCTTGTATTACGACTTGGGACTGCCATATCGCGATCAAACAGATGACCAAGTGACAATCGATGCAGCTCACGCAATTTTGAAGCACAATGTCGGCATCAAATGCGCGACAATCACACCCGACGAGCAGCGCGTTGAAGAGTTCAAGCTGAAAAAGATGTGGCTTTCACCAAACGGTACGATTAGAAACATTCTCGGCGGAACAGTGTTCAGAGAACCGATTCTGTGCAGCAATATCCCGCGTCTTGTTCCTGGCTGGACAAATCCAATTGTCATCGGTCGTCATGCTTTCGGCGATCAGTATCGAGCAAAGGATTTGGTGATTTCAAAGCCTGGCAAAGTTTCACTCAAATTTGTCGGAGACGATGGCAAAGTTGAGGAGACTGAGGTTTTCCACTTCAAGAATGGCGGTGTTATGCTCGGCATGTACAACACCGACGACAGCATCGCAGCCTTCGCTCACTCGTCATTCCAAGTCGCTCTTCAGAAGGGCTGGCCTCTTTACATGTCGACCAAGAACACCATTTTGAAGAAGTACGACGGCCGCTTCAAGGACATCTTCCAAGAAATCTTTGAGAAACACTACGAGAAACAATTCAACGATGCGAAAATTTGGTACGAGCATCGATTAATTGACGACATGGTCGCACAAGCTTTGAAGTCATCAGGAAAATTCGTTTGGGCCTGCAAGAACTACGACGGTGACGTTCAGTCGGACATTGTTGCTCAGGGTTATGGCTCACTTGGATTGATGACTTCAGTGCTCATGTGCCCTGATGGAAAAACGATTGAAGCTGAGGCTGCTCATGGTACTGTCACCAGACATTACAGACAGCATCAACAAGGTAAGCCCACCAGCACAAACCCAATCGCATCAATTTTCGCATGGACCAGAGGATTCGAACATCGTGCAAAGTTGGACAACAACCCAGACCTCGCACGTTTTGCTCAATCGCTTGAGAAGTCGTGCATCGACACGGTTGAGTCTGGAAAGATGACAAAGGACTTGGCCGGTTGCATTCACGGATTGAGTAATGTCAAGGAGGGCATGTACTTGAACACAGAGGACTTCTTAGAGGCCATTGCTGAACAGTTGAACCGCTCGTGGAAGAAG
Protein: 441 (aa)
MAFALSKIAKCINKNAFVTPLSSAMSSKNYSSGSRVEVAKPVVEMDGDEMTRIIWQFIKDKLIFPYVKVECLYYDLGLPYRDQTDDQVTIDAAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCSNIPRLVPGWTNPIVIGRHAFGDQYRAKDLVISKPGKVSLKFVGDDGKVEETEVFHFKNGGVMLGMYNTDDSIAAFAHSSFQVALQKGWPLYMSTKNTILKKYDGRFKDIFQEIFEKHYEKQFNDAKIWYEHRLIDDMVAQALKSSGKFVWACKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGFEHRAKLDNNPDLARFAQSLEKSCIDTVESGKMTKDLAGCIHGLSNVKEGMYLNTEDFLEAIAEQLNRSWKK
| Type | Start | End | Length |
| CDS |
27117 |
27204 |
88 |
| CDS |
28683 |
28750 |
68 |
| CDS |
28870 |
29052 |
183 |
| CDS |
29123 |
30106 |
984 |
| intron |
27205 |
28682 |
1478 |
| intron |
28751 |
28869 |
119 |
| intron |
29053 |
29122 |
70 |
Auto annotation result
| Program/Analysis | Accession | Description | Score/Expectation |
| BLASTP/NCBI-nr |
XP_312860 |
AGAP003168-PA [Anopheles gambiae str. PEST] gb|EAA08466.6| AGAP003168-PA [Anopheles gambiae str. PEST] |
0.0 |
| InterPro |
IPR004790 |
Isocitrate dehydrogenase NADP-dependent, eukaryotic-type |
|
| InterPro |
IPR024084 |
Isopropylmalate dehydrogenase-like domain |
|
| InterPro |
IPR019818 |
Isocitrate/isopropylmalate dehydrogenase, conserved site |
|
| Gene Ontology(BP) |
GO:0006102 |
isocitrate metabolic process |
|
| Gene Ontology(BP) |
GO:0055114 |
oxidation-reduction process |
|
| Gene Ontology(MF) |
GO:0004450 |
isocitrate dehydrogenase (NADP+) activity |
|
| Gene Ontology(MF) |
GO:0000287 |
magnesium ion binding |
|
| Gene Ontology(MF) |
GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
|
| Gene Ontology(MF) |
GO:0051287 |
NAD binding |
|
| Pfam |
PF00180.15 |
Isocitrate/isopropylmalate dehydrogenase |
2.7e-77 |
| Pfam |
PF03971.9 |
Monomeric isocitrate dehydrogenase |
0.0077 |
Expression level (RPKM)
Paralog/Ortholog genes
Paralogous genes
Orthologous genes
| Species |
Gene ID |
| B. mori |
BGIBMGA007586-TA |
| H. sapiens |
ENSP00000410513 |
| H. sapiens |
ENSP00000438457 |
| P. humanus |
PHUM450200-PA |
| A. mellifera |
GB14517-PA |
| H. melpomene |
HMEL003005-PA |
| T. castaneum |
TC011647 |
| D. plexippus |
DPOGS212995PA |
| A. gambiae |
AGAP006660 |
| H. sapiens |
ENSP00000260985 |
| D. plexippus |
DPOGS204316PA |
| P. humanus |
PHUM098590-PA |
| B. mori |
BGIBMGA006907-TA |
| H. sapiens |
ENSP00000331897 |
| H. sapiens |
ENSP00000446147 |
| A. aegypti |
AAEL000746 |
| M. musculus |
ENSMUSG00000025950 |
| P. vanderplanki |
Pv.04634 |
| C. quinquefasciatus |
CPIJ000337 |
| D. melanogaster |
FBgn0001248 |
| H. sapiens |
ENSP00000390265 |
| H. melpomene |
HMEL015140-PA |
| A. aegypti |
AAEL012614 |
| N. vitripennis |
NV11525-PA |
| S. invicta |
SI2.2.0_10465 |
| C. quinquefasciatus |
CPIJ003304 |
| A. gambiae |
AGAP003168 |
| T. castaneum |
TC014590 |