MidgeBase gene description page [Pn.00703]

Outline

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Gene ID Pn.00703
Type Protein coding gene
Scaffold PnScaf749
Start 20806
End 24141
Direction -

Sequence

Transcript: 3201 (bp)

 ATGTCACAAGGTGTTCTTAGATTGTGCACATTAGGCGGGGAGCATTTACTACGAATTCCAAAGCCGCTTCACCCAGCACGTCTATTTTCTGGAACCGTAAAACTCTTGAACAAAGATGGAAAACCGGTCGAGGCTATTCGCGGCATTCCCTATAAGAAACTCACCATCGGTGTTCCAAAGGAGAGATGGGCAAATGAGAAAAGAGTGGCAATGTCACCTGCAGCCACTGCGGCATTAGTCAAAAAGGGCTTCACCGTTCAGATTGAAAAGGGCGCGGGAGAAGAGGCAAAGTTCAGAGATCAAGATTTTACAGATGCCGGTGCAAAAATCGTCGATGGAAACAAGGCTTGGGACTCAGATATTTTACTTAAAATTCGTCAACCAACAGAGCAAGAGATCCCTCTTTTGAGAGAAAACTCTACGCTCATTTCATTCCTCTATCCAGGTCAGAATAAAGATCTTTTAAATGAGTTGGCGAAGAAGAAGATTAATGCATTTGCCATGGATTGTGTTCCTCGTATTTCTCGTGCGCAAGTGTTTGATGCGCTAAGCTCAATGGCTAACATTGCCGGTTACCGAGCCGTCATCGAAGCTGCCAATCACTTCCCTCGTTTCTTCACTGGCCAGATTACAGCAGCTGGTAAAGTTCCTCCTGCCAAAATTCTTGTAATTGGTGCTGGCGTCGCTGGTTTAGCCGCATGCGGTCAAGCTAAGAACATGGGTGCTATTGTGCGTGCTTTTGATACACGTGCCGCAGCAAAAGAGCAAGTTGAATCGATGGGAGCAGAGTTCTTGACAATCAACATTCAAGAAGATGGCTCAACGGCTGGAGGCTACTCAAAAGAGATGAGCAAGGAATTCATCGATGCCGAGATGGCGTTGTTCGCAAAACAATGCAAGGAGGTCGATGTCATCATAACCACTGCCCTGATTCCAGGAAAGAAGGCTCCGATTTTAATCAAGGAAGAGCACATCAAGTCAATGAAGCCCGGCAGCGTTGTCGTTGACTTGGCTGCCGAAGCTGGTGGAAACATCGAAACCATCGAACCCGGCAAAATTGTCACCAAGCACGGAGTTGTTCACATCGGTCTTACGGATTTACCTTCACGATTGCCGACGCAAGCCTCGACTTTGTATGCCAACAACATTTCAAAACTTCTCCTTTCAATGGGCGAGAAGGATCACTTTGATATTAACATGAAGGACGACGTGGTTCGCGGCAGCATCGTGGCACACAATGGGGAAGTAACGTGGCCACCACCCGTCATTTCAGTCTCCGCTCAACCCCAGCAAGCTCCTGCCAAGAAGGAAGGACAGGCAATTGTTCAAGCCACACCGCCGAATCCCTTCAGAGACACAATGACGAGTGCTCTCACCTACACTACTGGCCTCGGCACACTAATCACTCTCGGTGCCGTTTCACCGAATCCAGCATTTACTACTATGATGTCGACCTTTGCGCTTTCGGGCATCGTCGGCTATCACACTGTTTGGGGTGTCATTCCTGCCCTCCACTCGCCGCTCATGTCGTGCACAAATGCCATTTCGGGAATAACAGCGGTCGGCGGTCTTTTGCTCATGGGTGGAGGATATTTTCCCACAAACTCAATTGAGGTGCTATCAGCGGGAGCTGCACTTATTTCGTTTGTCAACATTTTCGGAGGATTCTTAGTCACACAGCGCATGTTGGACATGTTCAAGCGTCCAACAGATCCACCAGAATACAACTACCTGTACGGTATTCCCGCGGCAGTCTTCTTGGGTGGCTATGGACTTTCGGCATTGAATGGACTCGCCGAAGTCAATCAAATCGCCTACCTTGCCTCCTCTTTGTGCTGCGTCGGTGCATTGAGCGGTTTGTCATCGCAAAAGACTGCACGCTTGGGAAATGCGCTCGGTATCATCGGTGTTACTGGTGGCATTGCTGCCACATTAGGAATTCTGGCGCCTACCCCTGAGGTTCTTGCTCAAATGGCTGGATGTGCTGGTATCGGAGGACTCCTTGGAACTGTCATTGCGAAGAGAATTCAAATTACCGACTTGCCCCAATTGGTTGCCGGATTCCACTCACTTGTCGGTCTCGCTGCTGTACTCACTTGCGTTGCTACATACATGCACGACTTCCCGAACTTGGCAACCGATCCGGCAGCAAATGTTTTGCGCACAGCTTTATTCCTCGGAACATACATTGGTGGTGTGACTTTCTCGGGATCACTTGTAGCCTATGGAAAACTTCAAGGCGTTTTGAACTCTGCTCCACTACTTTTACCCGGTCGCCACTTTATTAATGGTGGTCTTTTGGCTGGAAACGCTGCAGCAATGGCCGCTTTCTTTATGGACCCAACAATGATCGGTGGCTTGTCGTGTCTCGGAGCCACTGCCGCACTATCGACGGTTATGGGAGTAACACTAACAGCAGCTATCGGAGGTGCAGACATGCCTGTAGTTATTACCGTTTTGAACTCGTATTCAGGATGGGCATTGTGCGCCGAAGGTTTCATGTTGAACAATAACTTGATGACCATCGTCGGTGCACTCATCGGAAGCTCTGGTGCAATTCTTTCTTACATCATGTGCAAAGCTATGAATCGCTCGCTGCCAAATGTCATTCTCGGAGGATATGGAACGTCGAGCACTGGAGGCGGAAAACCACAAGAAATTGTCGGCACACACACAGAAGTGTCGGTTGAAGGCACGGTGGACATGATCAAGAACGCAAAGAACATCATCATCACTCCAGGCTACGGTCTCTGTGTCGCAAAGGCTCAATATCCGATCGCTGAGATGGTTGAAATTTTGAAGAAGAGAGGAAAGAACGTCCGTTTCGGTATTCATCCAGTTGCTGGCCGCATGCCTGGTCAATTGAACGTGTTGTTGGCCGAAGCCGGTGTGAGCTATGATGACGTACTGGAAATGGAAGAGATCAATGATGACTTTGGAGAAACTGATTTGGTTTTGGTTATTGGTGCTAACGATACAGTCAACAGCGCGGCCGAGGATGATCCAAACTCAATTATTGCAGGAATGCCTGTTTTGAAAGTATGGAAAGCCGATCAAGTCGTAGTCATGAAGCGTTCACTTGGTGTTGGATATGCTGCCGTCGACAACCCTATCTTCTACAAGCCAAACACAGCAATGTTGCTTGGAGATGCCAAGAAAACATGTGATGCACTCCTGGCTAAGATCAAAGAAGACGAAGCT 

Protein: 1067 (aa)

 MSQGVLRLCTLGGEHLLRIPKPLHPARLFSGTVKLLNKDGKPVEAIRGIPYKKLTIGVPKERWANEKRVAMSPAATAALVKKGFTVQIEKGAGEEAKFRDQDFTDAGAKIVDGNKAWDSDILLKIRQPTEQEIPLLRENSTLISFLYPGQNKDLLNELAKKKINAFAMDCVPRISRAQVFDALSSMANIAGYRAVIEAANHFPRFFTGQITAAGKVPPAKILVIGAGVAGLAACGQAKNMGAIVRAFDTRAAAKEQVESMGAEFLTINIQEDGSTAGGYSKEMSKEFIDAEMALFAKQCKEVDVIITTALIPGKKAPILIKEEHIKSMKPGSVVVDLAAEAGGNIETIEPGKIVTKHGVVHIGLTDLPSRLPTQASTLYANNISKLLLSMGEKDHFDINMKDDVVRGSIVAHNGEVTWPPPVISVSAQPQQAPAKKEGQAIVQATPPNPFRDTMTSALTYTTGLGTLITLGAVSPNPAFTTMMSTFALSGIVGYHTVWGVIPALHSPLMSCTNAISGITAVGGLLLMGGGYFPTNSIEVLSAGAALISFVNIFGGFLVTQRMLDMFKRPTDPPEYNYLYGIPAAVFLGGYGLSALNGLAEVNQIAYLASSLCCVGALSGLSSQKTARLGNALGIIGVTGGIAATLGILAPTPEVLAQMAGCAGIGGLLGTVIAKRIQITDLPQLVAGFHSLVGLAAVLTCVATYMHDFPNLATDPAANVLRTALFLGTYIGGVTFSGSLVAYGKLQGVLNSAPLLLPGRHFINGGLLAGNAAAMAAFFMDPTMIGGLSCLGATAALSTVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFMLNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSTGGGKPQEIVGTHTEVSVEGTVDMIKNAKNIIITPGYGLCVAKAQYPIAEMVEILKKRGKNVRFGIHPVAGRMPGQLNVLLAEAGVSYDDVLEMEEINDDFGETDLVLVIGANDTVNSAAEDDPNSIIAGMPVLKVWKADQVVVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALLAKIKEDEA 
Type Start End Length
CDS 20809 20987 179
CDS 21059 21463 405
CDS 21525 24141 2617
intron 20988 21058 71
intron 21464 21524 61

Auto annotation result

Program/Analysis Accession Description Score/Expectation
BLASTP/NCBI-nr XP_312859 AGAP003167-PA [Anopheles gambiae str. PEST] gb|EAA08455.4| AGAP003167-PA [Anopheles gambiae str. PEST] 0.0
InterPro IPR004571 NAD(P) transhydrogenase, alpha subunit
InterPro IPR007698 Alanine dehydrogenase/PNT, NAD(H)-binding domain
InterPro IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal
InterPro IPR012136 NADP transhydrogenase, beta subunit
InterPro IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal
Gene Ontology(BP) GO:0015992 proton transport
Gene Ontology(BP) GO:0055114 oxidation-reduction process
Gene Ontology(CC) GO:0016021 integral to membrane
Gene Ontology(MF) GO:0050661 NADP binding
Gene Ontology(MF) GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity
Pfam PF00205.17 Thiamine pyrophosphate enzyme, central domain 0.18
Pfam PF10606.4 Homer-binding domain of metabotropic glutamate receptor 0.034
Pfam PF13450.1 NAD(P)-binding Rossmann-like domain 0.032
Pfam PF00107.21 Zinc-binding dehydrogenase 0.0011
Pfam PF05222.10 Alanine dehydrogenase/PNT, N-terminal domain 8.6e-47
Pfam PF01134.17 Glucose inhibited division protein A 0.022
Pfam PF02826.14 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 0.00014
Pfam PF02233.11 NAD(P) transhydrogenase beta subunit 1.7e-203
Pfam PF01262.16 Alanine dehydrogenase/PNT, C-terminal domain 6.6e-55
Pfam PF12769.2 Domain of unknown function (DUF3814) 6.9e-31

Expression level (RPKM)

Paralog/Ortholog genes

Paralogous genes

Gene ID

Orthologous genes

Species Gene ID
H. melpomene HMEL015141-PA
H. sapiens ENSP00000264663
A. aegypti AAEL012616
M. musculus ENSMUSG00000025453
A. gambiae AGAP003167
H. sapiens ENSP00000426343
H. sapiens ENSP00000343873
C. quinquefasciatus CPIJ003305
P. humanus PHUM394600-PA
B. mori BGIBMGA007502-TA
P. vanderplanki Pv.14705
D. plexippus DPOGS204223PA
T. castaneum TC013213